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Chinese Science Bulletin 2008年第S1期53卷 87-94页

作者： XiaoSi Tian Cheng Zhu XinWang Xu ChunMei Ma ZhiBin Sun qian yin Qing Zhu Wei Shi Nanjing Univ Sch Geog and Oceanog Sci Nanjing 210093 Peoples R China.

The oxygen and carbon isotopic ratios in human and animal tooth enamel were measured to reconstruct the subsistence patterns on Zhongba Site between 2400 and 4200 *** results indicate that human consumed chiefly C4 resources,such as millet,and the C3 plants,such as rice and wheat,constituted only a small fraction of the human diets,normally no more than 15%.There are significant differences in food sources between human and pig,and the percentages of C3 plants in pig diets were higher than those in human *** theδ13C values of pig partially overlap those of human,demonstrating some similarities in their food *** differences in water sources between human and pig are *** are significant differences in food and water sources between cattle and deer. This indicates that the two kinds of mammals subsisted in different *** theirδ13C values also partially overlap each other,suggesting some similarities in their food *** are both signifi- cant differences in meanδ13C andδ18O values between the omnivores,human and pig and the herbi- vores,cattle and deer,implying significant differences in food and water sources between the two *** the period the dietary habits of human had not changed,but the pig breeding strategies had changed,from breeding in house to breeding in confinement,and the proportion of C3 plants in pig food increased with *** scope of human migration had been considerably large by the Warring States because of the development of productive forces.

关键词： Zhongxian County in Chongqing City Zhongba Site tooth enamel δ13C δ18O C3 plants C4 plants palaeodiet reconstruction

Mechanical properties and microstructure of rolled and electrodeposited thin copper foil

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Rare Metals 2016年第12期35卷 909-914页

作者： Xiang-qian yin Li-Jun Peng Saif Kayani Lei Cheng Jian-Wei Wang Wei Xiao Li-Gen Wang Guo-Jie Huang State Key Laboratory of Nonferrous Metals & Processes General Research Institute for Nonferrous Metals Metal Materials Division Korea Institute of Materials Science

Commercial grade rolled and electrodeposited copper foils from Japan and China were selected, and their mechanical properties and microstructure were investigated. It was observed that there are notable differences in fracture strength, elongation at break and hydrophilicity between rol- led and electrodeposited copper foils. The rolled copper foils have higher tensile strength, lower ductility and larger static contact angle than electrodeposited copper foils. The rolled copper foils contain a [^-fiber texture, and the electrodeposited copper foils have random crystalline orientations. It was also observed that the rolled foils have packed grains, and elec- trodeposited foils have equiaxial grains. The uniform fine grain size and a few substructures of Japanese electrode- posited foils are major reasons for their higher elongation.

关键词： Copper foil Rolling Electrodepositing Texture Substructure

HIV Cure and HIV Reservoirs

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Biomedical and Environmental Sciences 2014年第6期27卷 478-480页

作者： yin qian qian Shao Yi Ming MA Li ying State Key Laboratory for Infection Disease Prevention and Control National Center for AIDS/STD Control and Prevention (NCAIDS) Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseas Chinese Center for Disease Control and Prevention (China-CDC)

The success of combined antiretroviral therapy （cART） has dramatically improved the clinical outcomes of HIV infection and made HIV infection a chronic disease. Nonetheless, cART alone cannot eliminate viral reservoirs and fully recover patients＇ health, so the patients have to receive this treatment for lifetime. Therefore, researchers have focused their efforts on the cure for HIV infection. In recent years, some intriguing and inspiring cases indicated that the cure of HIV infection （HIV cure） or durable alleviation of HIV infection may not be a dream any more. ＇Berlin Patient＇＇Mississippi Baby＇, and probably ＇Long Beach Baby＇ have brought great hope to the HIV cure. Many scientists believe that the HIV cure is just a question of time.

关键词： HIV Cure and HIV Reservoirs ZFN

Improving interface adhesion in TiNi wire/shape memory epoxy composites using carbon nanotubes

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Rare Metals 2021年第4期40卷 934-938页

作者： Xue Feng Li-Min Zhao Xu-Jun Mi Guo-Jie Huang Hao-Feng Xie Xiang-qian yin Li-Jun Peng Zhen Yang State Key Laboratory of Nonferrous Metals and Process General Research Institute for Nonferrous MetalsBeijing 100088China College of Materials Science and Engineering Liaocheng UniversityLiaocheng 252059China

In order to increase both the interfacial strength and interphase region strength between TiNi wires and shape memory epoxy,a novel interface structure including aminated CNTs was *** morphology shows that after electroplating and etching,continuous and homogeneous concave-convex layers form on the surface of astreated TiNi wires,meanwhile aminated CNTs were planted on the surface which could react with shape memory epoxy at the interface *** interfacial shear strength increases first with the CNT content rising but then a dramatic drop happens,and the maximum is obtained at CNT content of 0.6 g·L^(-1),which is about twice the result of acid etching TiNi wires.

关键词： Interfacial strength Interface structure Carbon nanotube Shape memory material Composite

成年小鼠心肌细胞腺病毒转染及缺氧/复氧诱导损伤模型的建立

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中国实验动物学报 2024年第4期32卷 435-443页

作者：李笑汝姚新叶刘佳张小玉张依曼来宝长马强王一东田红燕殷倩西安交通大学第一附属医院周围血管科西安710061 西安交通大学心血管研究中心西安710061 西安交通大学第一附属医院心血管内科西安710061

目的采用非Langendorff方法分离成年小鼠心肌细胞(adult mouse cardiomyocytes, AMCMs),并建立腺病毒转染及缺氧/复氧诱导细胞损伤模型,为应用AMCMs进行心肌缺血体外实验的研究提供便捷、实用、可操作性强的系统方法。方法应用非Lange... 详细信息

目的采用非Langendorff方法分离成年小鼠心肌细胞(adult mouse cardiomyocytes, AMCMs),并建立腺病毒转染及缺氧/复氧诱导细胞损伤模型,为应用AMCMs进行心肌缺血体外实验的研究提供便捷、实用、可操作性强的系统方法。方法应用非Langendorff方法分离AMCMs,观察贴壁后2、24、48及72 h细胞的形态,计算存活率,并应用α-actinin免疫荧光染色观察AMCMs完整性;应用腺病毒转染AMCMs,观察并统计转染36、48 h后的转染效率;通过缺氧45 min/复氧24 h,进行碘化丙啶(propidium iodide, PI)染色,统计PI阳性细胞率以明确缺氧/复氧损伤模型的建立。结果与AMCMs贴壁后2 h相比,贴壁后24和48 h的细胞存活率无显著下降,贴壁后72 h的细胞存活率显著下降;AMCMs细胞结构完整,可进行腺病毒转染,36和48 h转染效率分别可达82.07%±0.60%和82.84%±1.18%;缺氧/复氧诱导AMCMs可成功建立细胞损伤模型,PI染色阳性细胞达42.28%±3.10%。结论本研究应用非Langendorff方法分离培养的AMCMs,细胞存活率高,并建立腺病毒转染和缺氧/复氧诱导细胞损伤模型,为体外建立AMCMs基因修饰、缺氧/复氧损伤模型提供了简单易行的系统方法。

关键词： AMCMs提取腺病毒转染缺氧/复氧

新型缓释载体材料在草地贪夜蛾引诱剂中的应用

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环境昆虫学报 2024年第1期46卷 236-242页

作者：李红卫钱寅杰于艳雪赵雪晴谌爱东程志强翟俊峰中国检验检疫科学研究院植物检验与检疫研究所北京100176 吉林农业大学植物保护学院长春130118 云南省农业科学院农业环境资源研究所昆明650205

比较不同草地贪夜蛾引诱剂的田间诱集效果差异,筛选出长持效期引诱剂使用的缓释载体材料,为草地贪夜蛾的长期种群监测提供重要的理论依据。本研究首先将新型材料海藻酸钙/聚己内酯微球作为缓释载体应用于草地贪夜蛾引诱剂1,对其结构性... 详细信息

比较不同草地贪夜蛾引诱剂的田间诱集效果差异,筛选出长持效期引诱剂使用的缓释载体材料,为草地贪夜蛾的长期种群监测提供重要的理论依据。本研究首先将新型材料海藻酸钙/聚己内酯微球作为缓释载体应用于草地贪夜蛾引诱剂1,对其结构性能进行相关分析;通过田间诱集试验比较引诱剂1、引诱剂2、引诱剂3、引诱剂4、引诱剂5等五种不同草地贪夜蛾引诱剂的田间持续监测诱集效果;利用气相色谱仪定量比较两种诱集效果不同载体材料的引诱剂1(最优)、引诱剂2(最差)中所含性信息素组分的缓释能力。结果表明:新型材料海藻酸钙/聚己内酯微球的蛙卵状球形结可使草地贪夜蛾引诱剂1中信息素组分缓慢释放,室内静置2个月后该载体基本结构保持稳定;五种不同草地贪夜蛾引诱剂的持续诱捕能力对比为:引诱剂1>引诱剂5>引诱剂4>引诱剂3>引诱剂2,引诱剂1使用80 d仍然具有很强的引诱效果;通过对比诱集持续效果最优及最差的2种引诱剂1、引诱剂2所用载体的缓释性能,发现田间诱集持续效果最好的引诱剂1对草地贪夜蛾性信息素组分的缓释效果显著优于引诱剂2。海藻酸钙/聚己内酯微球作为载体材料可使草地贪夜蛾引诱剂的诱集持效期达80 d以上,可实现对草地贪夜蛾危害周期全覆盖,为持续开展草地贪夜蛾种群监测奠定了重要理论基础。

关键词：海藻酸钙/聚己内酯微球引诱剂缓释草地贪夜蛾

The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke

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Neuroscience Bulletin 2023年第9期39卷 1375-1395页

作者： Yuxing Zhang Xin Zhao Chun Guo ying Zhang Fukang Zeng qian yin Zhong Li Le Shao Desheng Zhou Lijuan Liu Department of Neurology The First Hospital of Hunan University of Chinese MedicineChangsha410007China Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases Changsha410208China Hunan University of Chinese Medicine Changsha410006China Laboratory of Prevention and Transformation of Major Diseases in Internal Medicine of Traditional Chinese Medicine Changsha410007China

Ischemic stroke is a major public health problem *** the circadian clock is involved in the process of ischemic stroke,the exact mechanism of the circadian clock in regulating angiogenesis after cerebral infarction remains *** the present study,we determined that environmental circadian disruption(ECD)increased the stroke severity and impaired angiogenesis in the rat middle cerebral artery occlusion model,by measuring the infarct volume,neurological tests,and angiogenesis-related *** further report that Bmal1 plays an irreplaceable role in *** of Bmal1 promoted tube-forming,migration,and wound healing,and upregulated the vascular endothelial growth factor(VEGF)and Notch pathway protein *** promoting effect was reversed by the Notch pathway inhibitor DAPT,according to the results of angiogenesis capacity and VEGF pathway protein *** conclusion,our study reveals the intervention of ECD in angiogenesis in ischemic stroke and further identifies the exact mechanism by which Bmal1 regulates angiogenesis through the VEGF-Notch1 pathway.

关键词： Circadian clock Ischemic stroke Angiogenesis VEGF Notch pathway

Research on Fiber Optic Surface Plasmon R ***:A Review

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Photonic Sensors 2024年第2期14卷 1-30页

作者： Qi WANG Dianyun ZHANG Yizhuo qian Xiangyu yin Lei WANG Shushuai ZHANG Yuyang WANG State Key Laboratory of Synthetical Automation for Process Industries Northeastern UniversityShenyang 110819China College of Information Science and Engineering Northeastern UniversiyShenyang 110819China Hebei Key Laboratory of Micro-Nano Precision Optical Sensing and Measurement Technology Qinhuangdao 066004China State Key Laboratory of Chemo/Biosensing and Chemometrics Hunan UniversityChangsha 410082China

Due to the benefits of the high sensitivity,real-time response,no labeling requirement,and good selectivity,fiber optic sensors based on surface plasmon resonance(SPR)have gained popularity in biochemical sensing in recent *** current research on such sensors is hot in enhancing sensitivity,improving detection accuracy,and achieving the detection of biochemical *** goal of this work is to present a thorough overview of recent developments in the optical fiber SPR biosensor ***,it explores the basic principles and sensing structures of optical fiber SPR biosensors,focusing on four ***,this paper introduces three fiber optic surface plasmon biosensors:SPR,localized surface plasmon resonance(LSPR),and long-range surface plasmon resonance(LRSPR).Each concept is explained from the perspective of the basic principles of fiber optic SPR ***,a classification of fiber optic SPR biosensors in health monitoring,food safety,environmental monitoring,marine detection,and other applications is introduced and ***,this paper summarizes the current research directions of SPR ***,it provides a prospective outlook on how fiber optic SPR sensors will develop in the future.

关键词： Surface plasmon resonance biosensors optical fiber sensors sensitivity

Study on City Environment,Safety and Health from the Viewpoint of Ecological Risks

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Agricultural Science & Technology 2011年第1期12卷 74-76页

作者： yin qian-liang School of Tourist and Urban Management Jiangxi University of Finance and EconomicsNanchang 330032

Urban ecological risk analysis is a relatively new study *** industrial modernization and urbanization have significantly improved the living standards of the ***,as environmental,safety and health issues are causing widespread concern,these problems have potential serious threat on ecosystems and human *** how to solve many problems arising from city has become a key to sustainable development of human *** present article analyzed the major problems that the city confronts and pointed out the main measures from the aspects of urban environment,safety and health.

关键词： Urban environment Urban safety Healthy city Risk

Effect of the potential function and strain rate on mechanical behavior of the single crystal Ni-based alloys:A molecular dynamics study

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Chinese Physics B 2021年第8期30卷 206-210页

作者： qian yin Ye-Da Lian Rong-Hai Wu Li-qiang Gao Shu-Qun Chen Zhi-Xun Wen School of Mechanics Civil Engineering and ArchitectureNorthwestern Polytechnical UniversityXi'an 710129China Key Laboratory of Advanced Functional Materials Education Ministry of ChinaBeijing University of TechnologyBeijing 100124China

Molecular dynamics has been widely used to study the fundamental mechanism of Ni-based ***,the effect of the potential function and strain rate on mechanical behavior has rarely been mentioned in the previous molecular dynamics *** the present work,we show that the potential function of molecular dynamics can dramatically influence the simulation results of single crystal Ni-based *** microstructure and mechanical behavior of single crystal Ni-based superalloys under four commonly used potential functions are systematically compared.A most suitable potential function for the mechanical deformation is critically selected,and based on it,the role of strain rate on the mechanical deformation is investigated.

关键词： defects intermetallic alloys and compounds microstructure simulation and modeling