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Anti-Phase Relationship Between the East Asian Winter Monsoon and Summer Monsoon During the Holocene?

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Journal of Ocean University of China 2017年第2期16卷 175-183页

作者： ge qian XUE Zuo YAO Zhigang ZANG Zhengchen CHU Fengyou Second Institute of Oceanography State Oceanic AdministrationHangzhou 310012P.R.China Key Laboratory of Submarine geosciences State Oceanic AdministrationHangzhou 310012P.R.China Department of Oceanography and Coastal Sciences Louisiana State UniversityBaton RougeLA 70803USA Center for Computation and Technology Louisiana State UniversityBaton RougeLA 70803USA Coastal Studies Institute Louisiana State UniversityBaton RougeLA 70803USA Key Laboratory of Physical Oceanography Ocean University of ChinaQingdao 266100P.R.China

The relationship between the East Asian winter monsoon(EAWM) and East Asian summer monsoon(EASM) during the Holocene is complicated and remains *** this study,analysis of grain size and benthic foraminiferal oxygen isotope,as well as accelerator mass spectrometry ^(14)C dating was performed on a sediment core retrieved from the newly revealed muddy deposit on the northern South China Sea continental *** history of the EAWM and EASM were reconstructed for the last 8200 a *** analysis in conjunction with previously published paleo-climate proxies revealed that the relationship between the EAWM and EASM during the Holocene is more complex than a simple and strict anti-phase one-both negative and positive correlations were *** EAWM and EASM are negatively correlated around 7500,4800,4200,3200,and 300 a BP(cooling periods),while positively correlated around 7100,3700,and 2100 a BP(warm periods).In particular,both the EAWM and EASM intensified during the three positive correlation ***,we also found that the relationship between these two sub-monsoons is anti-phase during the final phase of particularly hot periods like Holocene Optimum and Medieval warm *** possible impact from variations of solar irradiance on the relationship between the EAWM and EASM was also discussed.

关键词： grain size oxygen isotope South China Sea East Asian winter monsoon East Asian summer monsoon Holocene

Linking Monsoon Activity with River-Derived Sediments Deposition in the Northern South China Sea

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Journal of Ocean University of China 2019年第5期18卷 1098-1104页

作者： ge qian XU Dong YE Liming YANG Kehong YAO Zhigang Key Laboratory of Submarine geosciences State Oceanic AdministrationHangzhou 310012China Second Institute of Oceanography Ministry of Natural ResourcesHangzhou 310012China Key Laboratory of Physical Oceanography Ocean University of ChinaQingdao 266100China

The history of the East Asian monsoon(EAM)since Last Glacial Maximum is reconstructed based on records in a sediment core retrieved from the northern South China *** provenance of organic carbon and the EAM’s evolution are investigated using combined organic carbon,grain size,and AMS 14 C dating *** to the strong winter monsoon,the marine organic matter was dominated in the sediments,andδ13 C of organic matter was high during the last glacial *** the Holocene,the primary productivity decreased and the dilution effect of riverine inorganic clastics ***,the total organic carbon contents andδ13 C values decreased,and terrestrial organic matter content increased in the core *** 4μm grain size fraction,as the environmental sensitive grain size component,is determined to reconstruct the paleoclimatic *** the last glacial period,the contents of 4μm grain size component were mainly controlled by the sea level *** the Holocene,the influence of the sea level changes weakened and the roles of current system and provenance *** correlation between the EAM and solar insolation forcing is also discussed in this paper.

关键词： organic carbon grain size sea level current system South China Sea East Asian monsoon

Effect of Fumed SiO_2 on Pore Formation Mechanism and Various Performances of β-iPP Microporous Membrane Used for Lithium-ion Battery Separator

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Chinese Journal of Polymer Science 2018年第4期36卷 536-545页

作者： Lei Ding Guan Xu qian ge Tong Wu Feng Yang Ming Xiang State Key Laboratory of Polymer Materials Engineering Polymer Research Institute of Sichuan University

In this work, four samples containing different contents of fumed SiO_2 were prepared to improve the pore size distribution and various properties of b nucleated isotatic polypropylene（b-i PP） biaxial membrane used for lithium-ion battery separator. The wide-angle X-ray diffraction（WAXD） and differential scanning calorimetry（DSC） results show that the fumed SiO_2 promotes the formation of b-crystal slightly and narrows down the thickness distribution of b-lamellae; meanwhile, evenly distributed SiO_2 within b-i PP can be inspected by scanning electron microscopy（SEM）. Moreover, further detailed characterization of morphological evolutions during biaxial stretching by tensile testing and SEM manifests that SiO_2 can strengthen b-i PP and make the samples deform more homogeneously, resulting in a gradually elaborate and finer oriented microfibril structure after longitudinal stretching, in which more uniform defects distribute between fibrils and restrain the formation of coarse fibrils effectively. Therefore, more superior microporous structure emerges with the addition of SiO_2, accompanied by narrower pore size distribution and better connectivity between microvoids, which is confirmed by mercury porosimeter and diminished Gurley value. Moreover, the lower thermal shrinkage, decreased shrinkage rate and suppressed porosity reduction indicate that fumed SiO_2 improves thermal and dimensional stability of membrane dramatically. Furthermore, due to the excellent wettability of SiO_2 with electrolyte, the microporous membranes doped with SiO_2 have higher electrolyte uptake, even after heat treatment at elevated temperature.

关键词： β Nucleated polypropylene Fumed SiO2 Microporous membrane Pore size distribution Thermal stability and wettability

Dispersal of the Zhujiang River(Pearl River) derived sediment in the Holocene

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Acta Oceanologica Sinica 2014年第8期33卷 1-9页

作者： ge qian LIU J.P. XUE Zuo CHU Fengyou Key Laboratory of Submarine geosciences State Oceanic AdministrationSecond Institute of OceanographyState Oceanic Administration Department of Marine Earth and Atmospheric SciencesNorth Carolina State UniversityRaleighNC 27695USA

High-resolution Chirp profiling and coring reveals an elongated （ca. 400 km） Holocene Zhujiang River （Pearl River）-derived mud area （maximum thickness 〉 20 m） extending from the Zhujiang River Delta, southwest-ward off the Guangdong coast, to the Leizhou Peninsula. Two depo-centers, one proximal and one distal, are identified. On the continental shelf off the west Guangdong Province, the mud is deposited in water depth shallower than 50 m; while to the southeast of the Zhujiang River Estuary, the mud area can extend to the -120 m isobath. A combined analysis with the stratigraphic sequences of other muddy deposits in the West-ern Pacific marginal seas （mainly Changjiang （Yangtze） and Huanghe （Yellow） Rivers derived） indicates that the initiation of the Zhujiang River muddy deposit can be further divided into two stages： Stage 1 is before the mid-Holocene sea-level highstand （ca. 7.0 cal. ka BP）, the proximal mud was mostly deposited after 9.0 cal. ka BP, when the sea-level rose slowly after the Meltwater Pulse -1C; Stage 2, after the mid-Holocene sea-level highstand, clinoform developed on the continental shelf off the west Guangdong Province, extending ca. 400 km from the Zhujiang River Estuary. The proximal clinoform thins offshore, from ca. 10 m thickness around 5-10 m water depth to less than 1-2 m around 20-30 m water depth. In addition, we also find a de-veloped distal clinoform in the east of the Leizhou Peninsula.

关键词： South China Sea Zhujiang River mud clinoform

genome-wide interrogation of transfer RNA-derived small RNAs in a mouse model of traumatic brain injury

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Neural Regeneration Research 2022年第2期17卷 386-394页

作者： Xiao-Jian Xu Meng-Shi Yang Bin Zhang qian-qian ge Fei Niu Jin-qian Dong Yuan Zhuang Bai-Yun Liu Beijing Key Laboratory of Central Nervous System Injury Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Beijing Key Laboratory of Central Nervous System Injury and Department of Neurosurgery Beijing Neurosurgical Institute and Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Nerve Injury and Repair Center of Beijing Institute for Brain Disorders BeijingChina China National Clinical Research Center for Neurological Diseases BeijingChina

Transfer RNA(t RNA)-derived small RNAs(ts RNAs) are a recently established family of regulatory small non-coding RNAs that modulate diverse biological processes. Growing evidence indicates that ts RNAs are involved in neurological disorders and play a role in the pathogenesis of neurodegenerative disease. However, whether ts RNAs are involved in traumatic brain injury-induced secondary injury remains poorly understood. In this study, a mouse controlled cortical impact model of traumatic brain injury was established, and integrated ts RNA and messenger RNA(m RNA) transcriptome sequencing were used. The results revealed that 103 ts RNAs were differentially expressed in the mouse model of traumatic brain injury at 72 hours, of which 56 ts RNAs were upregulated and 47 ts RNAs were downregulated. Based on micro RNA-like seed matching and Pearson correlation analysis, 57 differentially expressed ts RNA-m RNA interaction pairs were identified, including 29 ts RNAs and 26 m RNAs. Moreover, gene Ontology annotation of target genes revealed that the significantly enriched terms were primarily associated with inflammation and synaptic function. Collectively, our findings suggest that ts RNAs may be associated with traumatic brain injury-induced secondary brain injury, and are thus a potential therapeutic target for traumatic brain injury. The study was approved by the Beijing Neurosurgical Institute Animal Care and Use Committee(approval No. 20190411) on April 11, 2019.

关键词： gene set enrichment analysis inflammation integrated analysis neurodegenerative disease next-generation sequencing secondary injury synaptic function transfer RNA-derived small RNAs transfer RNAs traumatic brain injury

Climate Projections of Spatial Variations in Coastal Storm Surges Along the Gulf of Mexico and *** Coast

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Journal of Ocean University of China 2017年第1期16卷 1-7页

作者： YAO Zhigang XUE Zuo HE Ruoying BAO Xianwen XIE Jun ge qian Key Laboratory of Physical Oceanography Ocean University of ChinaQingdao 266100P.R.China Department of Marine Earth and Atmospheric SciencesNorth Carolina State UniversityRaleighNC 27695USA Department of Oceanography and Coastal Sciences Louisiana State UniversityBaton Rouge 70803USA Center for Computation and Technology Louisiana State UniversityBaton Rouge 70803USA Coastal Studies Institute Louisiana State UniversityBaton Rouge 70803USA College of Oceanic and Atmospheric Sciences Ocean University of ChinaQingdao 266100P.R.China Second Institute of Oceanography State Oceanic AdministrationHangzhou 310012P.R.China

Using statistically downscaled atmospheric forcing, we performed a numerical investigation to evaluate future climate's impact on storm surges along the Gulf of Mexico and U.S. east coast. The focus is on the impact of climatic changes in wind pattern and surface pressure while neglecting sea level rise and other factors. We adapted the regional ocean model system(ROMS) to the study region with a mesh grid size of 7–10 km in horizontal and 18 vertical layers. The model was validated by a hindcast of the coastal sea levels in the winter of 2008. Model's robustness was confirmed by the good agreement between model-simulated and observed sea levels at 37 tidal gages. Two 10-year forecasts, one for the IPCC Pre-Industry(PI) and the other for the A1 FI scenario, were conducted. The differences in model-simulated surge heights under the two climate scenarios were analyzed. We identified three types of responses in extreme surge heights to future climate: a clear decrease in Middle Atlantic Bight, an increase in the western Gulf of Mexico, and non-significant response for the remaining area. Such spatial pattern is also consistent with previous projections of sea surface winds and ocean wave heights.

关键词： storm surge sea surface winds climate change regional ocean

Neutrophil-derived interleukin-17A participates in neuroinflammation induced by traumatic brain injury

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Neural Regeneration Research 2023年第5期18卷 1046-1051页

作者： Xiao-Jian Xu qian-qian ge Meng-Shi Yang Yuan Zhuang Bin Zhang Jin-qian Dong Fei Niu Hao Li Bai-Yun Liu Beijing Key Laboratory of Central Nervous System Injury Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Beijing Key Laboratory of Central Nervous System Injury and Department of Neurosurgery Beijing Neurosurgical Institute and Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Nerve Injury and Repair Center of Beijing Institute for Brain Disorders BeijingChina China National Clinical Research Center for Neurological Diseases BeijingChina

After brain injury, infiltration and abnormal activation of neutrophils damages brain tissue and worsens inflammation, but the mediators that connect activated neutrophils with neuroinflammation have not yet been fully clarified. To identify regulators of neutrophil-mediated neuroinflammation after traumatic brain injury, a mouse model of traumatic brain injury was established by controlled cortical impact. At 7 days post-injury(sub-acute phase), genome-wide transcriptomic data showed that interleukin 17 A-associated signaling pathways were markedly upregulated, suggesting that interleukin 17 A may be involved in neuroinflammation. Double immunofluorescence staining showed that interleukin 17 A was largely secreted by neutrophils rather than by glial cells and neurons. Furthermore, nuclear factor-kappaB and Stat3, both of which are important effectors in interleukin 17 A-mediated proinflammatory responses, were significantly activated. Collectively, our findings suggest that neutrophil-derived interleukin 17 A participates in neutrophil-mediated neuroinflammation during the subacute phase of traumatic brain injury. Therefore, interleukin 17 A may be a promising therapeutic target for traumatic brain injury.

关键词： immune infiltration innate immunity interleukin-17A neurodegenerative disease neuroinflammation neutrophils secondary brain injury transcription factor transcriptome traumatic brain injury

A STUDY ON THE ENSEMBLE FORECAST REAL-TIME CORRECTION METHOD

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Journal of Tropical Meteorology 2018年第1期24卷 42-48页

作者： GUO Rong QI Liang-bo ge qian-qian WENG Yong-yuan Shanghai Central Meteorological Observatory Shanghai 200030 China Shanghai Typhoon Institute of CMA Shanghai 200030 China Zhejiang University of Finance&Economics Hangzhou 300016 China Shanghai Meteorological Bureau Shanghai 200030 China

Using real-time correction technology for typhoons, this paper discusses real-time correction for forecasting the track of four typhoons during 2009 and 2010 in Japan, Beijing, Guangzhou, and Shanghai. It was determined that the short-time forecast effect was better than the original objective mode. By selecting four types of integration schemes after multiple mode path integration for those four objective modes, the forecast effect of the multi-mode path integration is better, on average, than any single model. Moreover, multi-mode ensemble forecasting has obvious advantages during the initial 36 h.

关键词： typhoon path real-time correction ensemble forecast track errors

Tandem Mass Tag-based proteomics analysis reveals the vital role of inflammation in traumatic brain injury in a mouse model

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Neural Regeneration Research 2023年第1期18卷 155-161页

作者： Jin-qian Dong qian-qian ge Sheng-Hua Lu Meng-Shi Yang Yuan Zhuang Bin Zhang Fei Niu Xiao-Jian Xu Bai-Yun Liu Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory of Central Nervous System Injury Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Center for Nerve Injury and Repair Beijing Institute of Brain DisordersBeijingChina China National Clinical Research Center for Neurological Diseases BeijingChina

Proteomics is a powerful tool that can be used to elucidate the underlying mechanisms of diseases and identify new ***,it may also be helpful for understanding the detailed pathological mechanism of traumatic brain injury(TBI).In this study,we performed Tandem Mass Tag-based quantitative analysis of cortical proteome profiles in a mouse model of *** results showed that there were 302 differentially expressed proteins in TBI mice compared with normal mice 7 days after *** Ontology and Kyoto Encyclopedia of genes and genomes pathway analyses showed that these differentially expressed proteins were predominantly involved in inflammatory responses,including complement and coagulation cascades,as well as chemokine signaling *** transcription factor analysis revealed that the inflammation-related transcription factors NF-κB1,RelA,IRF1,STAT1,and Spi1 play pivotal roles in the secondary injury that occurs after TBI,which further corroborates the functional enrichment for inflammatory *** results suggest that inflammation-related proteins and inflammatory responses are promising targets for the treatment of TBI.

关键词： bioinformatics complement cascade mass spectrometry neuroinflammation proteomics secondary injury subacute phase tandem mass tag transcription factor traumatic brain injury