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A UWB/IMU-Assisted Fingerprinting Localization Framework with Low Human Efforts

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China Communications 2024年第6期21卷 40-52页

With the rapid development of smart phone,the location-based services(LBS)have received great attention in the past *** to the widespread use of WiFi and Bluetooth devices,Received Signal Strength Indication(RSSI)fingerprintbased localization method has obtained much development in both academia and *** this work,we introduce an efficient way to reduce the labor-intensive site survey process,which uses an UWB/IMU-assisted fingerprint construction(UAFC)and localization framework based on the principle of Automatic radio map generation scheme(ARMGS)is proposed to replace the traditional manual *** be specific,UWB devices are employed to estimate the coordinates when the collector is moved in a reference point(RP).An anchor self-localization method is investigated to further reduce manual measurement work in a wide and complex environment,which is also a grueling,time-consuming process that is lead to artificial ***,the measurements of IMU are incorporated into the UWB localization algorithm and improve the label accuracy in *** addition,the weighted k-nearest neighbor(WKNN)algorithm is applied to online localization ***,filed experiments are carried out and the results confirm the effectiveness of the proposed approach.

关键词： indoor localization machine learning ultra wideband WiFi fingerprint

Surfactant-assisted crystallization of lysozyme and its mechanism

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Particuology 2024年第7期90卷 199-208页

作者： Yujie Song Rongfei Ren Min Su Zhihan Liang qi hao School of Chemical Engineering Hebei University of TechnologyTianjin 300130China

Surfactants were used to assist in the crystallization of *** types of surfactants with different structures(sodium dodecyl sulfate,cetyltrimethylammonium bromide,or betaine hydrochloride[BH])were *** study indicated that three surfactants were all capable of shortening the crystallization induction time of lysozyme,with BH inducing the shortest crystallization induction time(t=1 min)and the largest crystal size(37μm).The molecular interactions among each of the three surfactants aforementioned and lysozyme were also investigated by *** was found that hydrogen bonding dominantly acted between the carboxyl structure of the surfactant BH and the lysozyme,which produced the most favorable conformation for the self-assembly of lysozyme(promote lysozyme orderly aggregation and shorten the crystallization induction time).On this basis,the mechanism of surfactant-promoted lysozyme crystallization was proposed.

关键词： Protein Crystallization Surfactant Lysozyme Molecular interaction Mechanism

Optimization on crystallization process of the magnetic core lysozyme

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Particuology 2024年第4期87卷 106-113页

作者： Lixia Hou Chunxiao Qu Min Su Zhihan Liang qi hao School of Chemical Engineering Hebei University of TechnologyTianjin300130China

The continuous growth of the biomedical market highlights the significance of improvement in the ef-ficiency of batch production for protein drug ***,we investigated the effect of polymer-modified Fe_(3)O_(4) nanoparticles on lysozyme(Lys)crystallization at different conditions,using function-alized Fe_(3)O_(4) magnetic nanoparticles(Polymer C@Fe_(3)O_(4))as nucleation *** study revealed that the surface charge density of Polymer C@Fe_(3)O_(4) was highest at a modification mass ratio of Fe_(3)O_(4) to Polymer C is 8∶*** ratio facilitates the augmentation of electrostatic interaction and the promotion of *** adding 15%of the PolymerC@Fe_(3)O_(4) prepared from Fe_(3)O_(4) with an average particle size of 150 nm,the magnetic core lysozyme(M-Lys)crystals with an average particle size of 11.08μm,narrow size distribution,and regular morphology were obtained in a yield of 82.42%within 60 min.

关键词： Protein Crystallization Magnetic particle Lysozyme

Evaluation of lightning-induced overvoltage on a 10 kV distribution line based on electromagnetic return-stroke model using finite-difference time-domain

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High Voltage 2024年第2期9卷 356-366页

作者： Pan duan Lianfang Zhang Xiaogang Huang Jian Sun Yue qi qing Yang School of Automation Chongqing University of Posts and TelecommunicationsChongqingChina Chongqing Power Co Tongnan BurChongqingChina China Southern Power Grid Science Research Institute GuangzhouChina State Key Laboratory of Power Transmission Equipment&System Security and New Technology Chongqing UniversityChongqingChina

Accurate simulation of lightning-induced overvoltage for overhead distribution lines is helpful to prevent lightning trip *** electromagnetic return-stroke model was used to represent lightning and then a 3D finite-difference time-domain(FDTD)method was adopted to simulate the lightning-induced overvoltage on a distribution line without a field-line coupling *** lightning-induced overvoltage behave for different ground conductivity and varying distance between the distribution line and the lightning channel was *** results showed that the overvoltage waveforms at the centre point of the line corresponding to lightning strikes on the lossy ground and an ideal ground(σ=∞)were similar;however,the peak amplitudes of the waveform were affected by soil conductivity at a close *** relationship between magnitude of the overvoltage and distance can be described by a second-order exponential decay ***,the overvoltage calculated using the proposed model was compared with those obtained based on Agrawal's model and measurements made using the newly developed intelligent insulator on *** these comparisons,it could be concluded that the FDTD method with the electromagnetic return-stroke model produces reasonably accurate results of the attenuated oscillation waveform,which can better reproduce the overvoltage on operational distribution lines.

关键词： lightning distribution return

Efficient Direct Decomposition of NO over La_(0.8)A_(0.2)NiO_(3)(A=K, Ba, Y) Catalysts under Microwave Irradiation

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Journal of Wuhan University of Technology(Materials Science) 2024年第1期39卷 17-23页

作者：王浩 Zhao Zijian duan Xinghui ZHOU Shijia School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430070China

La_(0.8)A_(0.2)NiO_(3) (A=K,Ba,Y) catalysts supported on the microwave-absorbing ceramic heating carrier were prepared by the sol-gel *** crystalline phase and the catalytic activity of the La_(0.8)A_(0.2)NiO_(3)catalysts were characterized by XRD and H_(2) temperature-programmed reduction (TPR).The effects of reaction temperature,oxygen concentration,and gas flow rate on the direct decomposition of nitric oxide over the synthesized catalysts were studied under microwave irradiation (2.45 GHz).The XRD results indicated that the La_(0.8)A_(0.2)NiO_(3) catalysts formed an ABO_(3) perovskite structure,and the H_(2)-TPR results revealed that the relative reducibility of the catalysts increased in the order of La_(0.8)K_(0.2)NiO_(3)>La_(0.8)Ba_(0.2)NiO_(3)>La_(0.8)Y_(0.2)Ni O_(3).Under microwave irradiation,the highest NO conversion amounted to 98.9%,which was obtained with the La_(0.8)K_(0.2)NiO_(3) catalyst at 400℃.The oxygen concentration did not inhibit the NO decomposition on the La_(0.8)A_(0.2)NiO_(3) catalysts,thus the N_(2) selectivity exceeded 99.8%under excess oxygen at 550℃.The NOconversion of the La_(0.8)A_(0.2)NiO_(3) catalysts decreased linearly with the increase in the gas flow rate.

关键词： microwave catalysis direct decomposition of NO microwave-absorbing heating ceramics perovskite catalyst

Frontiers and future perspectives of neuroimmunology

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Fundamental Research 2024年第2期4卷 206-217页

作者： Hai qi Shumin duan Yanying Xu Hongliang Zhang School of Medicine Tsinghua UniversityBeijing 100084China Faculty of Medicine and Pharmaceutical Sciences Zhejiang UniversityHangzhou 310014China Department of Life Sciences National Natural Science Foundation of ChinaBeijing 100085China

Neuroimmunology is an interdisciplinary branch of biomedical science that emerges from the intersection of studies on the nervous system and the immune *** complex interplay between the two systems has long been *** efforts directed at the underlying functional interface and associated pathophysiology,however,have garnered attention only in recent *** this narrative review,we highlight significant advances in research on neuroimmune interplay and modulation.A particular focus is on early-and middle-career neuroimmunologists in China and their achievements in frontier areas of"neuroimmune interface","neuro-endocrine-immune network and modulation","neuroimmune interactions in diseases","meningeal lymphatic and glymphatic systems in health and disease",and"tools and methodologies in neuroimmunology research".Key scientific questions and future directions for potential breakthroughs in neuroimmunology research are proposed.

关键词： Neuroimmunology Neuroimmune interplay Neuro-endocrine-immune network Basic research Key scientific questions

Water modeling on fluid flow and mixing phenomena in a BOF steelmaking converter

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Journal of Iron and Steel Research International 2024年第3期31卷 595-607页

作者： Xin-yu Cai hao-jian duan Ding-han Li Anjun Xu Li-feng Zhang School of Metallurgical and Ecological Engineering University of Science and Technology Beijing(USTB)Beijing 100083China School of Mechanical and Materials Engineering North China University of TechnologyBeijing 100144China

A 1∶8 physical water model was constructed to investigate the fluid flow and mixing phenomena in the basic oxygen furnace(BOF)*** particle image velocimetry was employed to measure the velocity distribution of the bath and the high-speed camera was applied to capture the cavity shape in the combined blowing BOF *** mixing time for varied operating conditions was measured by the stimulus-response *** cavity depth increased with the decrease in the lance height and the increase in the top gas flow rate while the bottom blowing gas had little influence on the cavity *** minimum cavity depth was obtained under the condition of a 69.8 m^(3)/h top gas flow rate,a 287.5 mm lance height and a 0.93 m^(3)/h bottom blowing gas flow rate,which was 161.2 *** mixing time decreased as the lance height decreased and the top blowing gas flow rate *** mixing time was first decreased and then increased with the increase in the bottom gas flow *** the condition of 69.8 m^(3)/h gas flow rate of top blowing,the 287.5 mm lance height and the 0.93 m^(3)/h gas flow rate of bottom blowing,the mixing time in the converter was 48.65 *** empirical formula between the stirring power and the mixing time in the converter was calculated.

关键词： Water model Fluid flow Particle image velocimetry Mixing time BOF converter

Multifaceted functions of Drp1 in hypoxia/ischemia- induced mitochondrial quality imbalance: from regulatory mechanism to targeted therapeutic strategy

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Military Medical Research 2024年第4期11卷 589-615页

作者： Shuai hao He Huang Rui-Yan Ma Xue Zeng Chen-Yang duan Department of Anesthesiology the Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China Research Institute of General Surgery Jinling HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210002China Department of Cardiovascular Surgery Xinqiao HospitalArmy Medical UniversityChongqing 400037China Institute for Brain Science and Disease Chongqing Medical UniversityChongqing 400010China

Hypoxic-ischemic injury is a common pathological dysfunction in clinical *** are sensitive organelles that are readily damaged following ischemia and ***-related protein 1(Drp1)regulates mitochondrial quality and cellular functions via its oligomeric changes and multiple modifications,which plays a role in mediating the induction of multiple organ damage during hypoxic-ischemic ***,there is active controversy and gaps in knowledge regarding the modification,protein interaction,and functions of Drp1,which both hinder and promote development of Drp1 as a novel therapeutic ***,we summarize recent findings on the oligomeric changes,modification types,and protein interactions of Drp1 in various hypoxic-ischemic diseases,as well as the Drp1-mediated regulation of mitochondrial quality and cell functions following ischemia and ***,potential clinical translation prospects for targeting Drp1 are *** review provides new ideas and targets for proactive interventions on multiple organ damage induced by various hypoxic-ischemic diseases.

关键词： Dynamin-related protein 1(Drp1) Hypoxic-ischemic injury Mitochondrial quality imbalance Cell dysfunction Organ damage

Visualizing Wallerian degeneration in the corticospinal tract after sensorimotor cortex ischemia in mice

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Neural Regeneration Research 2024年第3期19卷 636-641页

作者： Jiao Mu Liufang hao Zijue Wang Xuyang Fu Yusen Li Fei hao Hongmei duan Zhaoyang Yang Xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina

Stroke can cause Wallerian degeneration in regions outside of the brain,particularly in the corticospinal *** investigate the fate of major glial cells and axons within affected areas of the corticospinal tract following stroke,we induced photochemical infarction of the sensorimotor cortex leading to Wallerian degeneration along the full extent of the corticospinal *** first used a routine,sensitive marker of axonal injury,amyloid precursor protein,to examine Wallerian degeneration of the corticospinal *** antibody to amyloid precursor protein mapped exclusively to proximal axonal segments within the ischemic cortex,with no positive signal in distal parts of the corticospinal tract,at all time *** improve visualization of Wallerian degeneration,we next utilized an orthograde virus that expresses green fluorescent protein to label the corticospinal tract and then quantitatively evaluated green fluorescent protein-expressing *** this approach,we found that axonal degeneration began on day 3 post-stroke and was almost complete by 7 days after *** addition,microglia mobilized and activated early,from day 7 after stroke,but did not maintain a phagocytic state over ***,astrocytes showed relatively delayed mobilization and a moderate response to Wallerian ***,no anterograde degeneration of spinal anterior horn cells was observed in response to Wallerian degeneration of the corticospinal *** conclusion,our data provide evidence for dynamic,pathogenic spatiotemporal changes in major cellular components of the corticospinal tract during Wallerian degeneration.

关键词： corticospinal tract green fluorescent protein microglia spinal anterior horn cells stroke virus trace Wallerian degeneration