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Journal of Energy Chemistry 2023年第5期80卷 247-255,I0007页

作者： Chuan Hu Fengli Wei Qinrui Liang Qiming Peng Yuting Yang Tayirjan taylor Isimjan Xiulin Yang guangxi Key Laboratory of Low Carbon Energy Materials School of Chemistry and Pharmaceutical SciencesGuangxi Normal UniversityGuilin 541004GuangxiChina Saudi Basic Industries Corporation(SABIC)at King Abdullah University of Science and Technology(KAUST) Thuwal 23955-6900Saudi Arabia

The construction of oxide/metal composite catalysts is a competent means of exploiting the electronic interactions between oxide/metal to enhance catalytic *** this work,we construct a novel heterogeneous composite(Ru/HfO_(2)-NC)with Ru/HfO2nanoparticles nested in nitrogen-doped porous carbon via a zeolitic imidazole frameworks-assisted(ZIF)co-precipitation and calcination *** particular,ZIF guides an in-situ construction of nested configuration and confines the scattered ***,Ru/HfO_(2)-NC exhibits unusual ORR activity,superb durability,and methanol tolerance in0.1 M KOH solution with high half-wave potential(E1/2)of 0.83 V and follows a near-4e-reaction ***,the ZAB assembled with cathodic Ru/HfO_(2)-NC outputs a power density of 157.3 m W cm^(-2),a specific capacity of 775 mA h g-1Zn,and a prolonged lifespan of 258 h at 5 mA cm^(-2).Meanwhile,the catalyst has demonstrated potential applicability in flexible *** suggested by experimental results and density functional theory(DFT)analysis,the remarkable property possibly originated from the optimization of the adsorption and desorption of reactive intermediates caused by the reconfiguration of the electronic structure between Ru and HfO_(2).

关键词： Ru/HfO_(2) Charge interaction Oxygen vacancy Oxygen reduction Zinc-air battery

The Influence of Avian Biodiversity and a Weedy Understorey on Canopy Arthropod Assembly

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Open Journal of Ecology 2014年第16期4卷 1003-1013页

作者： Kathryn Teare Ada Lambert nigel R. Andrew Paul g. McDonald Centre for Behavioural and Physiological Ecology Zoology University of New England Armidale Australia

Identifying the factor causing species decline from a multitude of potential disturbances is essential for successful management. Invasive species are often drivers of decline, either through direct effects such as recruitment limitation, or through indirect effects such as habitat modification that facilitate biota changes in other taxa. In this study, we tested the importance of bird predation on arthropods in eucalypt canopies in wet sclerophyll forest that had been invaded by the understorey weed Lantana camara. A strong top-down effect is in agreement with studies that show elevated numbers of insectivorous birds, such as the despotic bell miner, Manorina melanophrys, reduce damaging herbivorous insect numbers and their effect on tree health. Abundance, order and family composition were compared among sites, feeding guilds, among the presence and absence of a despotic bird, and among presence and absence within sites, using a three-way nested Multivariate Analysis of Variance (MANOVA), and tested our representation of insect feeding guilds with rarefaction curves. In total, we found arthropods from 20 families on eucalypt trees, 16 where bell miners were present and 18 where they were absent (a sampling efficiency of 78% and 92% of families based on the Chao-I index). Overall, there was a difference in the abundance of insects in areas where bell miners were present (n = 181), and where they were absent (n = 67). There was also a difference in the families present in areas with bell miners and without them. Under some conditions, despotic birds may not change the insect canopy community. Further studies should examine the effects of a despotic bird on the insect canopy community in a variety of conditions and throughout their range.

关键词： Despotic Birds Disturbance Insects Canopy Tritrophic Relationships

基于切口应力强度理论的135°拐角处应力场分析（英文）

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船舶力学 2015年第3期19卷 273-283页

作者：谌伟严仁军 nigel BARLTROP 杨平刘恩骞秦恺武汉理工大学交通学院船舶与海洋工程系高速船舶工程教育部重点实验室武汉430063 斯特莱斯克莱德大学船舶与海洋工程系英国格拉斯哥G40LZ

在焊接接头处,几何的不连续造成了局部的应力集中,形成了应力奇异效应,有必要做进一步的研究。文章基于切口应力强度理论,引入了奇异强度as的概念,提出了评估切口应力的简便算法,并通过一系列十字形模型进行了验证。最后,将修改表达式... 详细信息

在焊接接头处,几何的不连续造成了局部的应力集中,形成了应力奇异效应,有必要做进一步的研究。文章基于切口应力强度理论,引入了奇异强度as的概念,提出了评估切口应力的简便算法,并通过一系列十字形模型进行了验证。最后,将修改表达式的预估结果同N-SIF公式作了对比分析,结果表明该修正公式可以简单、准确地预估焊接接头处的应力。

关键词： 135°拐角应力奇异性奇异强度(as) 切口应力强度因子(N-SIF)

One Step Forward, Two Steps Back: Biconvergence of Washed Harmonic Series

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Advances in Pure Mathematics 2013年第3期3卷 309-316页

作者： Christopher M. Davis David g. taylor Department of Mathematics George Mason University Fairfax USA MCSP Department Roanoke College Salem USA

We examine variations of the harmonic series by grouping terms into “washings” that alternate sign with the number of terms in a washing growing exponentially with respect to a fixed base. The bases x = 1 and x = ∞ correspond to the alternating harmonic series and the usual harmonic series;we first consider other positive integral bases and further we consider positive real number bases with a unique way to make sense of adding a non-integral number of terms together. In both cases, we prove a remarkable result regarding the difference between the upper and lower convergent values of the series, and give some analysis of this behavior.

关键词： Harmonic Series Biconvergence Non-Integer Series

Utility of current thrombophilia screening in young patients with stroke and TIA

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Stroke & Vascular Neurology 2018年第4期3卷 231-236页

作者： Vafa Alakbarzade Alice taylor Marie Scully Robert Simister Arvind Chandratheva Hyper-acute Stroke Unit University College London Hospitals NHS Foundation TrustLondonUK Department of Haematology University College London Hospitals NHS Foundation TrustLondonUK

Introduction Approximately 40%of strokes in young adults are *** diagnostic yield of thrombophilia screening remains *** aimed to determine utility of current thrombophilia testing for young patients with stroke and transient ischaemic attack(TIA).Methods We present a retrospective review of all patients with stroke and TIA≤60 years presenting to University College London Hospital stroke unit and daily TIA clinic from 1 January 2015 to 1 August *** clinical records and thrombophilia tests,including factor V Leiden(FVL),prothrombin g20210A mutation(PgM),antiphospholipid antibody(APA),and protein S,C and antithrombin(AT)levels,were *** The mean age of 628 patients with stroke and TIA was 49.1 years(SD 9.2).Thrombophilia testing was performed in 360(57%)patients,including 171 with stroke and 189 with *** tests were found in 50(14%)patients,of whom 24 patients weregic stroke and 10(3%)with *** patients(4%)had homozygous/heterozygous FVL or PgM,and 27(7.5%)had positive APA(anticardiolipin antibody,anti-β2 glycoprotein antibody or lupus anticoagulant).Of 27(7.5%)patients with protein C,S or AT deficiency,10(2.8%)had primary deficiency,presumed hereditary with other secondary causes excluded.9%of patients with protein C,S or AT and 27%with APA were followed by confirmatory *** Thrombophilia testing was positive in only 14%of cases *** mutations and protein C,S or AT abnormalities were found rarely and were very uncommon in patients with ***-up of abnormal results was generally poor for all groups,which further limited the impact of the thrombophilia testing policy.

关键词： patients testing TIA

Persistent inflammation and neuronal loss in the mouse brain induced by a modified form of attenuated herpes simplex virus type I

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Virologica Sinica 2023年第1期38卷 108-118页

作者： Erlin Wang Xinwei Huang Yunshuang Ye Shiqing Zou guijun Chen Liping Yang nigel W.Fraser Fukai Bao Jumin Zhou Xia Cao Key Laboratory of Second Affiliated Hospital of Kunming Medical University Kunming650000China Key Laboratory of Animal Models and Human Disease Mechanism of the Chinese Academy of Science/Key Laboratory of Healthy Aging Research of Yunnan Province Kunming Institute of ZoologyThe Chinese Academy of SciencesKunming650223China Kunming College of Life Science University of Chinese Academy of SciencesKunming650204China Department of Microbiology Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA19104USA Department of Biology and Immunology Kunming Medical UniversityKunming650101China KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases Kunming650223China

Herpes simplex virus-1(HSV-1)is a widespread neurotropic virus that can reach the brain and cause a rare but acute herpes simplex encephalitis(HSE)with a high mortality *** patients present with changes in neurological and behavioral status,and survivors suffer long-term neurological *** date,the pathogenesis leading to brain damage is still not well ***-1 induced encephalitis in the central nervous system(CNS)in animals are usually very diffuse and progressing rapidly,and mostly fatal,making the analysis ***,we established a mouse model of HSE via intracerebral inoculation of modified version of neuralattenuated strains of HSV-1(deletion of ICP34.5 and inserting a strong promoter into the latency-associated transcript region),in which the LMR-αΔpA strain initiated moderate productive infection,leading to strong host immune and inflammatory response characterized by persistent microglia *** viral replication activity and prolonged inflammatory response activated signaling pathways in neuronal damage,amyloidosis,Alzheimer's disease,and neurodegeneration,eventually leading to neuronal loss and behavioral changes characterized by *** study reveals detailed pathogenic processes and persistent inflammatory responses in the CNS and provides a controlled,mild and non-lethal HSE model for studying long-term neuronal injury and increased risk of neurodegenerative diseases due to HSV-1 infection.

关键词： Herpes simplex virus-1(HSV-1) Herpes simplex encephalitis(HSE) ICP34.5 Neuroinflammation Neuronal loss

Calcium signaling and T-type calcium channels in cancer cell cycling

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World Journal of gastroenterology 2008年第32期14卷 4984-4991页

作者： James T taylor Xiang-Bin Zeng Jonathan E Pottle Kevin Lee Alun R Wang Stephenie g Yi lennifer A S Scruggs Suresh S Sikka Ming Li Department of Pharmacology Tulane University Health Sciences Center New Orleans LA 70112 United States Department of Urology Tulane University Health Sciences Center New Orleans LA 70112 United States Department of Physiology Tulane University Health Sciences Center New Orleans LA 70112 United States Department of Pathology Tulane University Health Sciences Center New Orleans LA 70112 United States

Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is essential for cells to enter and accomplish the S phase and the M phase of the cell cycle. In contrast, cancerous cells can pass these phases of the cell cycle with much lower cytoplasmic free calcium concentrations, indicating an alternative mechanism has developed for fulfilling the intracellular calcium requirement for an increased rate of DNA synthesis and mitosis of fast replicating cancerous cells. The detailed mechanism underlying the altered calcium loading pathway remains unclear; however, there is a growing body of evidence that suggests the T-type Ca2+ channel is abnormally expressed in cancerous cells and that blockade of these channels may reduce cell proliferation in addition to inducing apoptosis. Recent studies also show that the expression of T-type Ca2+ channels in breast cancer cells is proliferation state dependent, i.e. the channels are expressed at higher levels during the fast-replication period, and once the cells are in a non-proliferation state, expression of this channel isminimal. Therefore, selectively blocking calcium entry into cancerous cells may be a valuable approach for preventing tumor growth. Since T-type Ca2+ channels are not expressed in epithelial cells, selective T-type Ca2+ channel blockers may be useful in the treatment of certain types of cancers.

关键词： T-type calcium channels Cancer Cellcycle Calcium

Dietary substitution of soybean oil with coconut oil in the absence of dietary antibiotics supports growth performance and immune function in nursery and grower pigs

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Journal of Animal Science and Biotechnology 2020年第2期11卷 480-492页

作者： Andrea g.Braundmeier-Fleming Cassandra S.Skenandore Lesly gil Victoria Jacobsen Melissa Cregger taylor Badger Mallory Karr guoyao Wu Stephen B.Smith Annie E.Newell-Fugate Department of Medical Microbiology Immunology and Cell BiologySchool of MedicineSouthern Illinois UniversitySpringfieldIL 62702USA Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical SciencesTexas A&M University4466 TAMUCollege StationTX 77843USA Department of Animal Science Texas A&M University2471 TAMUCollege StationTX 77843USA

Background:We hypothesized that supplementation of nursery and grower pig diets with coconut oil in the absence of antibiotics would yield maintenance of glucose homeostasis,growth performance,and immune function similar to what is achieved with nursery and grower pig diets containing *** received the same base treatment diets from d24(weaning)to d71 of age and had blood and fecal samples collected on d24,d31,d45 and d71 for measurement of whole blood glucose,serum insulin,cortisol and cytokines,and fecal *** had weekly weights and daily feed consumption measured throughout the *** were euthanized at d71 and subcutaneous fat and ileal contents were collected for assessment for fatty acids and microbiome,*** treatments consisted of 2%soybean oil plus antibiotics(ABX;n=22),2%soybean oil without antibiotics(NABX;n=22),and 2%coconut oil without antibiotics(COC;n=22).Statistical analysis examined the effect of diet within each timepoint using a repeated measures ***:Pigs fed COC diet had decreased serum insulin levels,maintained feed intake,feed conversion and weight gain,and,based on serum cytokines and fecal microbiome,were immunologically similar to ABX-fed ***,NABX-fed pigs performed similarly to the ABX-fed pigs in all parameters except for serum ***,there was no difference in the incidence of diarrhea between any of the diet ***:This study demonstrates that dietary antibiotics are not necessary to maintain growth performance in nursery and grower ***,dietary antibiotics appear to modulate circulating cytokine *** coconut oil is neither harmful nor helpful to growth performance or immune function in nursery and grower pigs but does modulate serum insulin ***,while coconut oil fed at 2%by weight is a suitable substitute for dietary antibiotics,this study suggests that no substitute for dietary antibiotics is needed at all.

关键词： Alternatives Antibiotic supplementation grower pigs Medium chain fatty acids Nursery pigs Oil

Strategies towards statistically robust interpretations of in situ U-Pb zircon geochronology

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geoscience Frontiers 2016年第4期7卷 581-589页

作者： Christopher J.Spencer Christopher L.Kirkland Richard J.M.taylor The Institute of geoscience Research(TIgeR) Department of Applied GeologyWestern Australian School of MinesCurtin UniversityWA 6102Australia Centre for Exploration Targeting-Curtin Node Department of Applied GeologyWestern Australian School of MinesCurtin UniversityWA 6102Australia Australian Research Council Centre of Excellence for Core to Crust Fluid SystemsPerthWA 6102Australia

Zircon U-Pb geochronology has become a keystone tool across Earth science, arguably providing the gold standard in resolving deep geological time. The development of rapid in situ analysis of zircon （via laser ablation and secondary ionization mass spectrometry） has allowed for large amounts of data to be generated in a relatively short amount of time and such large volume datasets offer the ability to address a range of geological questions that would otherwise remain intractable （e.g. detrital zircons as a sedi- ment fingerprinting method）. The ease of acquisition, while bringing benefit to the Earth science com- munity, has also led to diverse interpretations of geochronological data. In this work we seek to refocus U -Pb zircon geochronology toward best practice by providing a robust statistically coherent workflow. We discuss a range of data filtering approaches and their inherent limitations （e.g. discordance and the reduced chi-squared; MSWD）. We evaluate appropriate mechanisms to calculate the most geologically appropriate age from both 238U/206pb and 207pb/206pb ratios and demonstrate the cross over position when chronometric power swaps between these ratios. As our in situ analytical techniques become progressively more precise, appropriate statistical handing of U-Pb datasets will become increasingly pertinent.

关键词： Zircon geochronology U-Pb geostatistics MSWD

澳大利亚新南威尔士梅杰克里克矿床的一个泥盆纪浅成热液金矿床

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地质地球化学 1991年第6期19卷 6-10,55页

作者： B.A.Wake g.R.taylor 曾提地化所广州分部

梅杰克里克金矿田的矿化脉主要由石英和碳酸盐脉组成,伴有Au,Au-Ag碲化物和贱金属硫化物,围岩为硅化、绢云母化岩墙或布雷德伍德花岗岩体的花岗闪长岩。流体包裹体研究揭示,沉淀作用是在350～380℃温度范围内由低盐度流体发生的。重要的... 详细信息

梅杰克里克金矿田的矿化脉主要由石英和碳酸盐脉组成,伴有Au,Au-Ag碲化物和贱金属硫化物,围岩为硅化、绢云母化岩墙或布雷德伍德花岗岩体的花岗闪长岩。流体包裹体研究揭示,沉淀作用是在350～380℃温度范围内由低盐度流体发生的。重要的Au-Ag碲化物矿化作用发生于155℃温度时。矿物沉淀是由于初始富CO_2含水流体中液相CO_2的分离造成的。所观察到的泥质蚀变是沸腾带上酸淋滤作用的结果。矿化作用属于浅成热液性质,可能是在热液对流体系存在时形成的。我们推断,毗邻的埃顿-亚尔瓦尔裂谷带中具有形成类似的浅成热液金矿床的条件。

关键词：金矿矿床热液型泥盆纪澳大利亚