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Antidiabetic and antioxidant activities of red seaweed Laurencia dendroidea

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Asian Pacific Journal of Tropical Biomedicine 2019年第12期9卷 501-509页

作者： The Han nguy.n Thi Huyen nguy.n Van Minh nguy.n Thi lan Phuong nguy.n Thi Van anh Tran anh Duy Do Sang Moo Kim Faculty of Food Technology Nha Trang University02 Nguyen Dinh Chieu StreetNha Trang CityKhanh HoaVietnam Quality Control Department Institute of Vaccines and Medical BiologicalsNha Trang CityKhanh HoaVietnam Faculty of Pharmacy University of Medicine and Pharmacy of Ho Chi Minh City41 Dinh Tien Hoang StreetHo Chi Minh CityVietnam Research Department of Marine Conservation Research Institute for Marine Fisheries224 Le Lai StreetHai Phong CityVietnam Department of Marine Food Science and Technology Gangneung-Wonju National University7 Jukheon-gilGangneung 25457Republic of Korea

Objective:To investigate antidiabetic and antioxidant activities of the extract and fractions from Vietnamese red seaweed Laurencia ***:The seaweed Laurencia dendroidea was extracted by using microwave-assisted extraction method in 80%*** seaweed extract was then fractionated using different solvents(n-hexane,chloroform,ethyl acetate,butanol and water).These obtained fractions were evaluated forα-glucosidase inhibitory and antioxidant *** activities were tested using DPPH,nitric oxide radical scavenging and metal chelating *** enzyme inhibition mode was determined using Lineweaver-Burk *** acidic and thermal stabilities,the ethyl acetate fraction was treated at pH 2.0 and 100℃,*** residual inhibitory activity of the fraction was calculated based on the initial inhibitory *** in vivo antidiabetic activity,mice were divided into four groups,including normal control,diabetic control,diabetic mice treated with ethyl acetate fraction and diabetic mice treated with *** glucose level of treated mice during acute and prolonged treatments was *** evaluate the toxicity of the ethyl acetate fraction,the body weight changes and activities of liver function enzymes(aspartate transaminase,alanine transaminase and gammaglutamyl transferase)were carried ***:The extract of Laurencia dendroidea showed strongα-glucosidase inhibitory and DPPH radical scavenging *** concentrations affected bothα-glucosidase inhibitory and antioxidant activities.A 80%aqueous methanol was the suitable solvent for extraction of enzyme inhibitors and *** solvent fractions,ethyl acetate fraction had the highest inhibitory activities againstα-glucosidase with a mixed type of inhibition and the strongest antioxidant activities,and was stable under acidic and thermal *** ethyl acetate fraction treated diabetic mice significantly reduced blood glucose level compare

关键词： α-Glucosidase inhibitor Antidiabetic Antioxidant Red seaweeds Vietnam

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FDI对越南企业发展的影响研究

FDI对越南企业发展的影响研究

作者：阮维英（nguy(?)n Duy anh）东华大学

学位级别：硕士

国际贸易与外商直接投资是两种重要的国际经济关系,传统上,人们将国际贸易与外商直接投资视作两种不同的经济现象,并分别加以研究。但是随着经济全球的日益深入,二者之间联系越来越密切,表现出相互促进和相互补充的交叉发展特征。20世... 详细信息

国际贸易与外商直接投资是两种重要的国际经济关系,传统上,人们将国际贸易与外商直接投资视作两种不同的经济现象,并分别加以研究。但是随着经济全球的日益深入,二者之间联系越来越密切,表现出相互促进和相互补充的交叉发展特征。20世纪80年代中期,越南实施“改革开放“的新政策,选择了积极融入世界经济体系和广泛与经济全球化的发展战略。25年来,大力吸引外国直接投资成为了越南开展对外经贸合作的重要部分。随着越南改革开放的不断深化,大量外资涌入越南。FDI的流入对越南的经济发展产生了广泛而深刻的影响,尤其08年金融危机爆发后,FDI的变已经成为影响越南经济波动的重要外部因素。FDI通过改变一国的信贷约束和资产价格影响企业的投资和生产决策行为,并通过金融加速器效应,引进经济的大幅波动。作为一名在华越南留学生,在企业管理专业研究生求学期间开始关注FDI对越南企业发展的影响问题,并将作为学位论文展开研究,形成论文.主要研究两个方面：研究越南的FDI通过对越南企业进出口的影响和FDI对于越南国内企业管理运营的影响。并且本人得出总体结论、第一：FDI在越南体现了显著的贸易创造效应。相比之下,越南内资企业的对外贸易总量则处于停滞不前的状态。总之FDI通过它的资本投入、技术投入、提升了越南贸易产品的国际竞争力,迅速扩展了国际市场空间。第二：外资给合资企业带来的新技术并没有对提高越南的国际竞争力做出最大贡献,越南利用外资来获得先进技术和由先进技术确定的竞争力提高的目的并没有完全实现。

关键词： [越南] [外商直接投资] [对外贸易] [企业管理]

汉越词对汉语教学的影响与教学策略——以《汉语教程》（第一册上、下）为例

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汉越词对汉语教学的影响与教学策略——以《汉语教程》（第一册上...

作者：段氏兰英（Doàn Th(?) lan anh）东北师范大学

学位级别：硕士

语言是文化最重要的载体,也是文化重要的组成部分。但任何一种语言的词汇系统不可能是完全封闭的,因为它们很难自足。再说,在交流过程中非靠语言不可。所以,在交流时所需要的语言需要接纳和吸收词汇来丰富自己,补充不足的地方,使语言能... 详细信息

语言是文化最重要的载体,也是文化重要的组成部分。但任何一种语言的词汇系统不可能是完全封闭的,因为它们很难自足。再说,在交流过程中非靠语言不可。所以,在交流时所需要的语言需要接纳和吸收词汇来丰富自己,补充不足的地方,使语言能不断地新陈代谢,使表达更精彩、更完善。中越两国的之间关系,大概是从公元前二世纪就已经开始了。这证明了越南在很多方面都受到过中国的影响。特别是语言,以前越南是一个落后的国家,没有文字,因此在两国间的交流中,大量的汉语词传到了越南,然后被越南人吸收、融合并使用。到现在,越南语里有一部分词是汉越词,这些词就是从汉语词汇借过来的,并受到越南的影响而发生改变,成为越南语不可缺少的一部分。从此,越南人在学习汉语过程中最感兴趣的问题就是汉越词,也就是说汉越词对越南学习者既有利又有弊。因为有不少汉越词发展到现在,在词义、用法上已经改变或消失。但本人认为,如果能够充分地利用汉越词与汉语词在词义方面的异同点来教越南学习汉语的人,就可以让他们快速掌握汉语词的意义和用法。所以,我把汉越词与汉语词对比分析作为研究对象。同时在越南语里找出汉越词对越南学习者的正迁移和负迁移,并指出汉越词会给越南学生带来的影响。从而帮助学生认出自己不足的地方,找到学习方法,并且帮助老师调整教学内容和教学方法以及如何克服学生偏误的方法。

关键词：汉越词影响正迁移负迁移教学

Efficacy of He-ne Laser in Combination with Topical Clindamycin in the Treatment of Acne Vulgaris (AV)

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Journal of Cosmetics, Dermatological Sciences and Applications 2020年第3期10卷 134-139页

作者： Bui Thi Van nguy.n ngoc Oanh Đặng Văn Em Huynh Thi Xuan Tam nguy.n lan anh Pham Thi Minh Phuong Dermatology-Venereology and Allergy 108 Central Military Hospital Hanoi Vietnam Dermatology-Venereology Department Bach Mai Hospital Hanoi Vietnam Pham ngoc Thach University of Medicine Ho Chi Minh City Vietnam

Objective: To evaluate the efficacy of He-ne laser in combination with topical clindamycin in the treatment of AV at 108 Military Central Hospital from Oct 2015 to Aug 2016. Subjects and Methods: 61 patients with AV w... 详细信息

Objective: To evaluate the efficacy of He-Ne laser in combination with topical clindamycin in the treatment of AV at 108 Military Central Hospital from Oct 2015 to Aug 2016. Subjects and Methods: 61 patients with AV were divided into 2 groups: Group 1: 31 patients were treated with He-Ne laser in combination with topical Clindamycin, Group 2: 30 patients were only treated with topical clindamycin. Laser HE-NE was applied 2 times/week n>for 6 weeks. Result: After 3 months of treatment Group 1: very good—51n>n>.6%, good—48.4%. Group 2: very good—30%, good—50% and moderate—20%. Conclusion: n>The combination of He-Ne laser with topical clindamycin shows more rapid clinical improvement compared to topical clindamycin alone in the treatment of mild and moderate AV.

关键词： Acne Vulgaris He-ne Laser Clindamycin

Study the Changes in Soil Organic Carbon of Rice-Maize Cropping System in the Top Layer of Alluvisol Soil in Dan Phuong: A Study of C-13 Stable Isotope Composition (<i>δ</i><sup>13</sup>C)

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Journal of Environmental Protection 2019年第10期10卷 1361-1372页

作者： nguy.n Thi Hong Thinh Vu Hoai Ha lan anh Vo Thi anh Truong Viet Chau Trinh Van Giap Tran Minh Tien Isotope Hydrology Laboratory Institute for Nuclear Science and TechnologyHanoiVietnam Soils and Fertilizers Research Institute HanoiVietnam

In this study, the experiments on field were conducted to examine the change in the content of soil organic carbon (SOC), its C-13 stable isotope composition (δ 13C) and some main physical, chemical parameters (soil moisture, pH, soil density, content of humic, fulvic, total n, total P, total K) in alluvial soil of Dan Phuong region—Vietnam at a depth of 0 - 30 cm when we changed the regime from 2 maize -1 rice crop to 2 rice - 1 maize crop per 1 year. In addition to analyzing the main parameters in soil, C content and its δ 13C value in parts of rice and maize (root, stem and leaf) were also analyzed to assess the contribution of plant residues on soil organic carbon content after harvest. The experiment was carried out in 2016-2017 on the field with the traditional farming method of local farmers along with the tropical monsoon weather conditions of the north-Vietnam. The results showed that SOC had positive correlation with total n, total P parameters and negative correlation with δ 13C values of soil samples at two layers (0 - 15 cm and 15 - 30 cm). The average of total dry biomass (stem, stump + roots and leaf parts) per 1 rice and 1 maize crop was 10.64 Mg/ha and 9.09 Mg/ha, respectively. The average of δ 13C value of rice (C3 plant) was -29.78‰ and its value of maize (C4 plant) was -12.61‰. The new plant (rice) contributes to the total soil organic carbon content from 11.31% to 44.14% at the 0 - 15 cm layer and from 6.55% to 11.31% at the 15 - 30 cm layer in one-year experiment period.

关键词： Soil Organic Carbon (SOC) C-13 Stable Isotope Maize and Rice Crop Soil Properties

异甘草素对醋氨酚诱导的急性肝细胞损伤的保护作用

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中国临床药理学与治疗学 2008年第3期13卷 293-298页

作者：章道华叶岚岚程昊余伟杨静郭鹏武汉大学基础医学院药理学系武汉大学药学院药物化学系

目的：研究异甘草素（isoliquiritigenin，ISL）对醋氨酚（AAP）诱导的肝细胞损伤的保护作用及机制。方法：以AAP 20mmol／L培养原代肝细胞12h造成急性化学性肝损伤模型。肝细胞随机分为正常组，AAP损伤组，ISL预处理组和ISL加n-硝基-L... 详细信息

目的：研究异甘草素（isoliquiritigenin，ISL）对醋氨酚（AAP）诱导的肝细胞损伤的保护作用及机制。方法：以AAP 20mmol／L培养原代肝细胞12h造成急性化学性肝损伤模型。肝细胞随机分为正常组，AAP损伤组，ISL预处理组和ISL加n-硝基-L-精氨酸甲酯（L-nAME）预处理组。酶学测定培养液ALT、AST活性，肝细胞CYP2E1活性和谷胱甘肽（GSH）含量，RT-PCR测定肝细胞CYP2E1 mRnA表达水平，放射免疫分析测定肝细胞cAMP和cGMP含量，三明治ELISA方法测定核转录调节因子（nF-κB等）活性。结果：ISL浓度（5～20μmol／L）依赖性抑制AAP引起的ALT和AST升高；下调肝细胞CYP2E1活性和mRnA表达，最大抑制率分别可达75．7％和78．7％，同时明显抑制AAP引起的肝细胞GSH含量下降；加入L-nAME 2．0mmol／L可阻断ISL 20μmol／L对肝细胞的保护作用；ISL不能逆转AAP引起的肝细胞cAMP含量下降，但可浓度依赖性提高cGMP含量（最高可达4、75倍）；ISL浓度依赖性抑制AAP所致nF-κB活性的提高，抑制率分别为24、8％、37．3％和64．1％。结论：ISL对CYP2E1介导的AAP肝细胞损伤具有保护作用，可能与通过nO-cGMP通路，抑制nF-κB激活和下调CYP2E1表达有关。

关键词：异甘草素醋氨酚肝细胞 CYP2E1 环鸟苷酸

急性等容性血液稀释在脑梗死病史患者脊柱手术中的可行性

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河南医学高等专科学校学报 2020年第5期32卷 497-501页

作者：白玉周一卢锡华孔岚杨楠木王建伟王根生郑州大学附属肿瘤医院麻醉与围术期医学科郑州大学附属肿瘤医院肝胆科郑州450003

目的观察急性等容性血液稀释(acute normovolemic hemodilution,anh)在有脑梗死病史患者脊柱肿瘤术中应用的可行性。方法选取脑梗死病史患者40例,按照随机数字表法分为观察组和对照组,各20例。观察组经桡动脉采血,经右颈内静脉补充等容... 详细信息

目的观察急性等容性血液稀释(acute normovolemic hemodilution,anh)在有脑梗死病史患者脊柱肿瘤术中应用的可行性。方法选取脑梗死病史患者40例,按照随机数字表法分为观察组和对照组,各20例。观察组经桡动脉采血,经右颈内静脉补充等容量晶体胶体。观察组红细胞比容(Hct)20%血容量或Hbanh用于有脑梗死病史患者脊柱肿瘤手术中,能够减少异体血使用,不影响凝血功能,围术期未诱发新发脑梗死。

关键词：脑梗死急性等容血液稀释血脂血糖凝血功能