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STUDY ON INHIBITION OF PANCREATIC EXOCRINE SECRETION BY SOMATOSTATIN IN RATS

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Chinese Medical Sciences Journal 1996年第3期11卷 166-169页

作者：何晓东 M.T.nelson H.Debas GastrointestinalResearchLaboratory DepartmentofSurgeryandPhysiologyUniversityofCafiforniaSchoolofMedicineSanFranciscoCalifornia

We used a potent and specific monoclonal antibody to somatostatin to test the physiologic inhibitory role of the tetradecapeptide somatostatin on pancreatic *** immunoneutralization increased both the total amylase and volume of pancreatic ***-A receptor antagonism abolished the stimulatory effect of somatostatin *** conclude that somatostatin tonically inhibits pancreatic secretion in fasted rats via inhibition of the release or action of ***,the source of these peptides is likely islet delta cells and intrapancreatic neurons,respectively.

关键词： amylase pancreas somatostatin

Jump further,leap higher,and consolidate stronger:A brief review of the long-term partnership between Kunming Institute of Zoology(KIZ)and the Chinese University of Hong Kong(CUHK)in bioresources and molecular research

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Zoological Research 2023年第3期44卷 556-558页

作者： nelson Tang Yong-Tang Zheng Hui Zhao Wai-Yee Chan Yong-Gang Yao KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases The Chinese University of Hong KongHong Kong SARChina KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650204China

The molecular etiologies of many prevalent diseases stem from genetic variations that arise during evolution and natural selection,as well as from environmental *** study of genetic diversity in human populations and analysis of molecular evolution in primates and other animal species can provide important insights regarding the pathogenesis of common diseases in both human and animal populations.

关键词： molecular evolution solid

Deep learning ferroelectric polarization distributions from STEM data via with and without atom finding

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npj Computational Materials 2021年第1期7卷 1342-1352页

作者： Christopher T.nelson Ayana Ghosh Mark Oxley Xiaohang Zhang Maxim Ziatdinov Ichiro Takeuchi Sergei V.Kalinin Center for Nanophase Materials Sciences Oak Ridge National LaboratoryOak RidgeTNUSA Computational Sciences and Engineering Division Oak Ridge National LaboratoryOak RidgeTNUSA Department of Materials Science and Engineering University of MarylandCollege ParkMDUSA

Over the last decade,scanning transmission electron microscopy(STEM)has emerged as a powerful tool for probing atomic structures of complex materials with picometer precision,opening the pathway toward exploring ferroelectric,ferroelastic,and chemical phenomena on the atomic *** to date extracting a polarization signal from lattice coupled distortions in STEM imaging rely on discovery of atomic positions from intensity maxima/minima and subsequent calculation of polarization and other order parameter fields from the atomic ***,we explore the feasibility of polarization mapping directly from the analysis of STEM images using deep convolutional neural networks(DCNNs).In this approach,the DCNN is trained on the labeled part of the image(i.e.,for human labelling),and the trained network is subsequently applied to other *** explore the effects of the choice of the descriptors(centered on atomic columns and grid-based),the effects of observational bias,and whether the network trained on one composition can be applied to a different *** analysis demonstrates the tremendous potential of the DCNN for the analysis of high-resolution STEM imaging and spectral data and highlights the associated limitations.

关键词： Deep network ferroelectric

Sensing grain and seed moisture and density from dielectric properties

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International Journal of Agricultural and Biological Engineering 2011年第1期4卷 75-81页

作者： Stuart O.nelson D.Sc.Samir Trabelsi U.S.Department of Agriculture Agricultural Research ServiceRussell Research CenterAthensGeorgiaU.S.A.

The importance of moisture measurement in grain and seed is discussed,and a brief history of the development of moisture sensing instruments,based on sensing of dielectric properties of these materials,is *** are presented graphically on the permittivities or dielectric properties of grain and seed showing their variation with frequency,moisture content,temperature,and bulk density,and references are cited for further *** recent developments on microwave measurements for moisture content and bulk density sensing are briefly described,and numerous studies are cited providing sources of information on these newer techniques.

关键词： sensing dielectric properties moisture content density permittivity cereal grain oilseed

The Cloud Model for Climate Change

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International Journal of Geosciences 2024年第5期15卷 366-395页

作者： Michael nelson David B. nelson Retired Pleasanton CA USA

In 1995, the Intergovernmental Panel on Climate Change (IPCC) released a thermodynamic model based on the Greenhouse Effect, aiming to forecast global temperatures. This study delves into the intricacies of that model. Some interesting observations are revealed. The IPCC model equated average temperatures with average energy fluxes, which can cause significant errors. The model assumed that all energy fluxes remained constant, and the Earth emitted infrared radiation as if it were a blackbody. Neither of those conditions exists. The IPCC’s definition of Climate Change only includes events caused by human actions, excluding most causes. Satellite data aimed at the tops of clouds may have inferred a high Greenhouse Gas absorption flux. The model showed more energy coming from the atmosphere than absorbed from the sun, which may have caused a violation of the First and Second Laws of Thermodynamics. There were unexpectedly large gaps in the satellite data that aligned with various absorption bands of Greenhouse Gases, possibly caused by photon scattering associated with re-emissions. Based on science, we developed a cloud-based climate model that complied with the Radiation Laws and the First and Second Laws of Thermodynamics. The Cloud Model showed that 81.3% of the outgoing reflected and infrared radiation was applicable to the clouds and water vapor. In comparison, the involvement of CO2 was only 0.04%, making it too minuscule to measure reliably.

关键词： Climate Change Greenhouse Gas CO2 Clouds Model Thermodynamics

Decoupling CO₂ from Climate Change

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International Journal of Geosciences 2024年第3期15卷 246-269页

作者： Michael nelson David B. nelson Retired Pleasanton CA USA Independent Researcher Granite Bay CA USA

This study determines if there is a correlation between rising carbon dioxide levels and global warming. Historical data were reviewed from three different time periods spanning 500 million years. It showed that the curves and trends were too dissimilar to establish a connection. Observations from CO2/temp ratios showed that the CO2 and the temperature moved in opposite directions 42% of the time. Many ratios displayed zero or near zero values, reflecting a lack of response. As much as 87% of the ratios revealed negative or near zero values, which strongly negate a correlation. The infrared spectra showed the Greenhouse Gases had an exceptionally low absorption band between 11.67 μm to 9.1 μm, which is a zone called the infrared atmospheric window. Most of the Greenhouse Gases absorb little infrared inside that zone. And that zone is where the Earth’s surface emits almost all infrared radiation. Even with minimal absorbance, water vapor captures the most infrared radiation. It absorbs 84 times more than CO2, 407 thousand times more than methane, 452 thousand times more than ozone and 2.3 million times more than nitrous oxide. The Intergovernmental Panel on Climate Change (IPCC) and the United States EPA excluded water vapor because it was not associated with man-made activities. They reported that water vapor and clouds were simply feedback mechanisms from CO2. Clouds reflect radiation from the sun. The Northern Hemisphere is 2.7°F warmer than the Southern Hemisphere because of clouds. The world cloud cover has gone down 4.1% from 1982 to 2018. Calculations show that this could be responsible for 2.4°F of the 2.7°F. The research shows that most of the recent increase in temperature (89.9%) is because of fewer clouds.

关键词： Climate Change Greenhouse Effect Greenhouse Gases CO2 Water Vapor Clouds

Corrigendum to Mercury photoreduction and photooxidation in lakes:effects of filtration and dissolved organic carbon *** of Environmental Sciences 68(2018)151-159

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Journal of Environmental Sciences 2021年第5期33卷 347-350页

作者： nelson J.O'Driscol Emma Vost Erin Mann Sara Klapstein Robert Tordon Matthew Lukeman Department o f Earth&Environmental Science.Acadia University WolfuilleNova ScotiaCanada B4P 2R62 Environment Canada DartmouthNova Scotia Department of Chemistry Acadia UniversityWolfuilleNova ScotiaCanada B4P 2R6

"Filtered(0.2μm)and unfiltered samples were analyzed for gross photoreduction,gross photooxidation,and net reduction rates of mercury using pseudo first-order curves.

关键词： lakes Mercury dissolved

Reconstructing the phytogeny of new world monkeys(platyrrhini):evidence from multiple non-coding loci

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Current Zoology 2019年第5期65卷 579-588页

作者： Xiaoping WANG Burton K.LIM nelson TING Jingyang HU Yunpeng LIANG Christian ROOS Li YU State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan Yunnan UniversityKunmingChina School of Life Sciences Yunnan UniversityKunmingChina epartm ent of Natural History Royal Ontario MuseumTorontoONCanada Department of Anthropology and Institute of Ecology and Evolution University of OregonEugeneOregonUSA State Key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of SciencesKunmingChina Kunming College of Life Science University of Chinese Academy of SciencesKunmingChina Gene Bank of Primates and Primate Genetics Laboratory German Primate CenterLeibniz Institute for Primate ResearchKellnerwegGottingenGermany

Among mammalian phylogenies,those characterized by rapid radiations are particularly *** New World monkeys(NWMs,Platyrrhini)comprise 3 families and 7 subfamilies,which radiated within a relatively short time ***,their phylogenetic relationships are still largely *** the present study,56 nuclear non-coding loci,including 33 introns(INs)and 23 intergenic regions(IGs),from 20 NWM individuals representing 18 species were used to investigate phylogenetic relationships among families and *** the 56 loci,43 have not been used in previous NWM *** applied concatenation and coalescence tree-inference methods,and a recently proposed question-specific approach to address NWM *** results indicate incongruence between concatenation and coalescence methods for the IN and IG ***,a consensus was reached with a single tree topology from all analyses of combined INs and IGs as well as all analyses of question-specific loci using both concatenation and coalescence methods,albeit with varying degrees of statistical *** detail,our results indicated the sister-group relationships between the families Atelidae and Pitheciidae,and between the subfamilies Aotinae and Callithrichinae among *** study provides insights into the disputed phylogenetic relationships among NWM families and subfamilies from the perspective of multiple non-coding loci and various tree-inference ***,the present phylogenetic framework needs further evaluation by adding more independent sequence data and a deeper taxonomic ***,our work has important implications for phylogenetic studies dealing with rapid radiations.

关键词： coalescence concatenation non-coding nuclear genes primates phylogenetics

Analysis of geo-spatiotemporal data using machine learning algorithms and reliability enhancement for urbanization decision support

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International Journal of Digital Earth 2020年第12期13卷 1717-1732页

作者： Kwame O.Hackman Xuecao Li Daniel Asenso-Gyambibi Emmanuella A.Asamoah Isaac.D.nelson Data Management Department WASCAL Competence CenterOuagadougouBurkina Faso Department of Geological and Atmospheric Sciences Iowa State UniversityAmesUSA Department of Environmental Management University of Energy and Natural ResourcesSunyaniGhana Building and Road Research Institute(BRRI) Council for Scientific and Industrial Research(CSIR)KumasiGhana

We present systematic analyses of the temporal dynamics of the growth of Kumasi,the fastest growing city in Ghana using 20-year Landsat timeseries data from 2000 to 2020(with 1986 Landsat image as a baseline).Two classification algorithms–random forest(RF)and support vector machines(SVM)–were used to produce binary(built-up/non-built up)maps for all years within the temporal *** further implemented an anomaly detection and temporal consistency algorithm followed by a changing logic to correct the classification anomalies due to image contamination from the cloud and other *** mean overall accuracies obtained for RF and SVM were 94.9%(kappa=0.90)and 95.5%(kappa=0.91),*** results reveal that the mean builtup area percentages of the metropolis are approximately 74,65,47,and 23 for the years 2020,2010,2000,and 1986,respectively,representing a mean annual change of 3.5%over the 34 *** the present lack of labeled data in Ghana for in-depth analyses of the evolution of land use,we believe that this study serves as an initial attempt to a better understanding of the effects of increasing anthropogenic activities due to urbanization,on human and environment health.

关键词： Urbanization Kumasi support vector machine random forest Landsat