系统性轻链淀粉样变:有望被治愈

作     者：刘扬 Nelson Leung 路瑾 Yang Liu;Nelson Leung;Jin Lu

作者机构：Peking University People’s HospitalPeking University Institute of HematologyNational Clinical Research Center for Hematologic DiseaseBeijing 100044China Division on Nephrology and HypertensionDivision of HematologyMayo ClinicRochester MN 55905USA 

出 版 物：《Science Bulletin》 (科学通报（英文版）)

年 卷 期：2023年第68卷第22期

页      面：2678-2681页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：淀粉样变 organs amyloid 

摘      要：Systemic light chain(AL)amyloidosis is a rare protein misfolding and deposition *** clonal plasma cells in the bone marrow of AL amyloidosis patients secrete an abnormal immunoglobulin or its fragment,which is deposited in various organs and leads to organ *** incidence in the USA is 8-14/million[1],whereas the incidence in China is undetermined.