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Radial artery pseudoaneurysm diagnosed by pointof-care ultrasound five days after transradial catheterization: A case report

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World Journal of Emergency Medicine 2018年第3期9卷 223-226页

作者： Stephen Alerhand Donald Apakama Adam Nevel Bret P.nelson Emergency Medicine Department Icahn School of Medicine at Mount Sinai

Dear editor,Radial artery pseudoaneurysm from arterial wall disruption is an extremely rare complication of arterial *** prior case reports describe this complication occurring from continuous blood pressure monitoring or serial blood-gas analysis requiring extended *** increasing use of radial artery access for coronary angiography and percutaneous coronary intervention(PCI)introduces another susceptible patient population.[1–4]We report a case of a 57-year-old female with right radial artery pseudoaneurysm,diagnosed by bedside ultrasound(US)in the emergency department(ED)five days after transradial cardiac catheterization.

关键词： point-of-care Radial artery pseudoaneurysm

Limitation and challenges in using pancreatic cancer-derived organoids as a preclinical tool

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Cancer Communications 2022年第10期42卷 1028-1031页

作者： Nicolas A.Fraunhoffer Analía Meilerman Abuelafia nelson Dusetti Juan Iovanna Cancer Research Center of Marseille InsermPaoli-Calmettes InstitutAix-Marseille UniversityScientific and Technological Park of LuminyMarseille 13288France Buenos Aires University Center for Pharmacological and Botanical StudiesFaculty of MedicineNational Council for Scientific and Technical ResearchBuenos Aires C1121ABGArgentina

Dear Editor,Pancreatic ductal adenocarcinoma(PDAC)is a dismal disease with a fast evolution and unpredictable treatment ***,FOLFIRINOX[1]and gemcitabine[2]are the preferred treatments with a response rate of 33%and 11%,*** poor patient response has been associated with an inefficient/non-personalized treatment ***,developing a rapid and efficient preclinical tool to test tumor drug sensitivity for each patient is hugely *** patient-derived organoid(PDO)appears to be a promising tool for developing individualized treatments for patients with *** PDO-based platforms are in development worldwide as a guide to optimize therapy by directing tailored treatments.A critical point to consider PDO as promising is that it must represent the great clinical heterogeneity of PDAC as much as ***,PDO has displayed histological features that mimic the PDAC phe*** characteristics make PDO an interesting option to obtaining reliable chemo-response profiles at a reasonable timeframe for most PDAC patients.

关键词： clinical patients treatment

CdS magic-size clusters exhibiting one sharp ultraviolet absorption singlet peaking at 361 nm

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Nano Research 2019年第6期12卷 1437-1444页

作者： Junbin Tang Juan Hui Meng Zhang Hongsong Fan nelson Rowell Wen Huang Yingnan Jiang Xiaoqin Chen Kui Yu Institute of Atomic and Molecular Physics Sichuan UniversityChengdu 610065China Engineering Research Center in Biomaterials Sichuan UniversityChengdu 610065China Metrology Research Centre National Research Council of CanadaOttawaOntario KIA 0R6Canada Laboratory of Ethnopharmacology West China School of MedicineSichuan UniversityChengdu 610065China Jilin Ginseng Academy Changchun University of Chinese MedicineChangchun 130117China State Key Laboratory of Polymer Materials Engineering Sichuan UniversityChengdu 610065China

We report,for the first time,the synthesis of CdS magic-size clusters (MSCs) which exhibit a single sharp absorption peaking at ~ 361 nm,along with sharp band edge photoemission at ~ 377 nm and broad trap emission peaking at ~ 490 *** MSCs are produced in a singleensemble form without the contamination of conventional quantum dots (QDs) and/or other-bandgap *** are denoted as *** present the details of several controlled syntheses done in oleylamine (OLA),using C,d(NO3)2 or C,d(OAc)2 as a C,d source and thioacetamide (TAA) or elementary sulfur (S) as a S source.A high synthetic reproducibility of the reaction of Cd(NO3)2 and TAA to single-ensemble MSC-361 is achieved,the product of which is not contaminated by other bandgap clusters and/or *** some cases,the reaction product exhibits an additional absorption peak at ~ 322 *** demonstrate that the two peaks,at 361 and 322 nm,do not evolve ***,the 322 nm peak is not a higher order electronic transition of MSC-361,but due to the presence of another ensemble,namely *** present study suggests that there is an outstanding need for the development of a physical model to narrow the knowledge gap regarding the electronic structure in these colloidal semiconductor CdS MSCs.

关键词： colloidal semiconductor CdS magic-size clusters (MSCs) MSC-361 quantum dots (QDs) electronic structures

STUDY ON INHIBITION OF PANCREATIC EXOCRINE SECRETION BY SOMATOSTATIN IN RATS

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Chinese Medical Sciences Journal 1996年第3期11卷 166-169页

作者：何晓东 M.T.nelson H.Debas GastrointestinalResearchLaboratory DepartmentofSurgeryandPhysiologyUniversityofCafiforniaSchoolofMedicineSanFranciscoCalifornia

We used a potent and specific monoclonal antibody to somatostatin to test the physiologic inhibitory role of the tetradecapeptide somatostatin on pancreatic *** immunoneutralization increased both the total amylase and volume of pancreatic ***-A receptor antagonism abolished the stimulatory effect of somatostatin *** conclude that somatostatin tonically inhibits pancreatic secretion in fasted rats via inhibition of the release or action of ***,the source of these peptides is likely islet delta cells and intrapancreatic neurons,respectively.

关键词： amylase pancreas somatostatin

Deep learning ferroelectric polarization distributions from STEM data via with and without atom finding

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npj Computational Materials 2021年第1期7卷 1342-1352页

作者： Christopher T.nelson Ayana Ghosh Mark Oxley Xiaohang Zhang Maxim Ziatdinov Ichiro Takeuchi Sergei V.Kalinin Center for Nanophase Materials Sciences Oak Ridge National LaboratoryOak RidgeTNUSA Computational Sciences and Engineering Division Oak Ridge National LaboratoryOak RidgeTNUSA Department of Materials Science and Engineering University of MarylandCollege ParkMDUSA

Over the last decade,scanning transmission electron microscopy(STEM)has emerged as a powerful tool for probing atomic structures of complex materials with picometer precision,opening the pathway toward exploring ferroelectric,ferroelastic,and chemical phenomena on the atomic *** to date extracting a polarization signal from lattice coupled distortions in STEM imaging rely on discovery of atomic positions from intensity maxima/minima and subsequent calculation of polarization and other order parameter fields from the atomic ***,we explore the feasibility of polarization mapping directly from the analysis of STEM images using deep convolutional neural networks(DCNNs).In this approach,the DCNN is trained on the labeled part of the image(i.e.,for human labelling),and the trained network is subsequently applied to other *** explore the effects of the choice of the descriptors(centered on atomic columns and grid-based),the effects of observational bias,and whether the network trained on one composition can be applied to a different *** analysis demonstrates the tremendous potential of the DCNN for the analysis of high-resolution STEM imaging and spectral data and highlights the associated limitations.

关键词： Deep network ferroelectric

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系统性轻链淀粉样变:有望被治愈

Science Bulletin 2023年第22期68卷 2678-2681页

作者：刘扬 nelson Leung 路瑾 Peking University People’s Hospital Peking University Institute of HematologyNational Clinical Research Center for Hematologic DiseaseBeijing 100044China Division on Nephrology and Hypertension Division of HematologyMayo ClinicRochester MN 55905USA

Systemic light chain(AL)amyloidosis is a rare protein misfolding and deposition *** clonal plasma cells in the bone marrow of AL amyloidosis patients secrete an abnormal immunoglobulin or its fragment,which is deposited in various organs and leads to organ *** incidence in the USA is 8-14/million[1],whereas the incidence in China is undetermined.

关键词：淀粉样变 organs amyloid

Jump further,leap higher,and consolidate stronger:A brief review of the long-term partnership between Kunming Institute of Zoology(KIZ)and the Chinese University of Hong Kong(CUHK)in bioresources and molecular research

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Zoological Research 2023年第3期44卷 556-558页

作者： nelson Tang Yong-Tang Zheng Hui Zhao Wai-Yee Chan Yong-Gang Yao KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases The Chinese University of Hong KongHong Kong SARChina KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650204China

The molecular etiologies of many prevalent diseases stem from genetic variations that arise during evolution and natural selection,as well as from environmental *** study of genetic diversity in human populations and analysis of molecular evolution in primates and other animal species can provide important insights regarding the pathogenesis of common diseases in both human and animal populations.

关键词： molecular evolution solid

Sensing grain and seed moisture and density from dielectric properties

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International Journal of Agricultural and Biological Engineering 2011年第1期4卷 75-81页

作者： Stuart O.nelson D.Sc.Samir Trabelsi U.S.Department of Agriculture Agricultural Research ServiceRussell Research CenterAthensGeorgiaU.S.A.

The importance of moisture measurement in grain and seed is discussed,and a brief history of the development of moisture sensing instruments,based on sensing of dielectric properties of these materials,is *** are presented graphically on the permittivities or dielectric properties of grain and seed showing their variation with frequency,moisture content,temperature,and bulk density,and references are cited for further *** recent developments on microwave measurements for moisture content and bulk density sensing are briefly described,and numerous studies are cited providing sources of information on these newer techniques.

关键词： sensing dielectric properties moisture content density permittivity cereal grain oilseed

The Cloud Model for Climate Change

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International Journal of Geosciences 2024年第5期15卷 366-395页

作者： Michael nelson David B. nelson Retired Pleasanton CA USA

In 1995, the Intergovernmental Panel on Climate Change (IPCC) released a thermodynamic model based on the Greenhouse Effect, aiming to forecast global temperatures. This study delves into the intricacies of that model. Some interesting observations are revealed. The IPCC model equated average temperatures with average energy fluxes, which can cause significant errors. The model assumed that all energy fluxes remained constant, and the Earth emitted infrared radiation as if it were a blackbody. Neither of those conditions exists. The IPCC’s definition of Climate Change only includes events caused by human actions, excluding most causes. Satellite data aimed at the tops of clouds may have inferred a high Greenhouse Gas absorption flux. The model showed more energy coming from the atmosphere than absorbed from the sun, which may have caused a violation of the First and Second Laws of Thermodynamics. There were unexpectedly large gaps in the satellite data that aligned with various absorption bands of Greenhouse Gases, possibly caused by photon scattering associated with re-emissions. Based on science, we developed a cloud-based climate model that complied with the Radiation Laws and the First and Second Laws of Thermodynamics. The Cloud Model showed that 81.3% of the outgoing reflected and infrared radiation was applicable to the clouds and water vapor. In comparison, the involvement of CO2 was only 0.04%, making it too minuscule to measure reliably.

关键词： Climate Change Greenhouse Gas CO2 Clouds Model Thermodynamics