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Fra.lty a.d ca.diova.cula. disea.e： potentia. role of ga.t speed in surgica. risk stra.ifica.ion in older a.ults

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Journa. of Geria.ric Ca.diology 2015年第1期12卷 44-56页

作者： michael a. Chen Ha.borview Medica. Center University of Washington School of Medicine 325 9th Avenue Box 359748 Seattle WA 98104 USA

Fra.lty is a.sta.e of la.e life decline a.d vulnera.ility, typified by physica. wea.ness a.d decrea.ed physiologic reserve. The epidemiology a.d pa.hophysiology of fra.lty sha.e fea.ures with those of ca.diova.cula. disea.e. Ga.t speed ca. be used a. a.mea.ure of fra.lty a.d is a.powerful predictor of morta.ity. a.va.cing a.e is a.potent risk fa.tor for ca.diova.cula. disea.e a.d ha. been a.socia.ed with a. increa.ed risk of a.verse outcomes. Older a.ults comprise a.proxima.ely ha.f of ca.dia. surgery pa.ients, a.d a.count for nea.ly 80% of the ma.or complica.ions a.d dea.hs following surgery. The a.ility of tra.itiona. risk models to predict morta.ity a.d ma.or morbidity in older pa.ients being considered for ca.dia. surgery ma. improve if fra.lty, a. mea.ured by ga.t speed, is included in their a.sessment. It is possible tha. in the future fra.lty a.sessment ma. a.sist in choosing a.ong thera.ies （e.g., surgica. vs. percuta.eous a.rtic va.ve repla.ement for pa.ients with a.rtic stenosis）.

关键词： Ca.dia. surgery Fra.lty Ga.t speed Risk scores Risk stra.ifica.ion

Effect of 5-a.a.2’-deoxycytidine on immune-a.socia.ed proteins in exosomes from hepa.oma

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World Journa. of Ga.troenterology 2010年第19期16卷 2371-2377页

作者： Ga.-Wa.Sa.ren Depa.tment of Histology a.d Embryology Inner Mongolia Medical College Hohhot 010010 Inner Mon-golia Autonomous Region China

a.M: To study the effect of 5-a.a.2’-deoxycytidine (5-a.a.CdR) on hea. shock protein 70 (HSP70), huma. leucocyte a.tigen-Ⅰ (Hla.Ⅰ) a.d NY-ESO-1 proteins in exosomes produced by hepa.oma.cells, HepG2 a.d Hep3B. METHODS: Exosomes derived from HepG2 a.d Hep3B cells trea.ed with or without 5-a.a.CdR were isola.ed a.d purified by ultra.iltra.ion centrifuga.ion a.d sucrose gra.ient ultra.entrifuga.ion. The number of exosomes wa. counted under electron microscope. Concentra.ion of proteins in exosomes wa. mea.ured by bicinchoninic a.id protein a.sa.. Expression of HSP70, Hla.Ⅰ a.d NY-ESO-1 proteins in exosomes wa. detected by Western blotting a.d immunoelectron microscopy. mRNa.expression of p53 gene wa. detected by reverse tra.scription polymera.e cha.n ***: The mRNa.expression of p53 gene wa. increa.ed in both hepa.oma.cell lines a.ter trea.ment with 5-a.a.CdR. The number of exosomes a.d the concentra.ion of tota. proteins in exosomes were increa.ed signifi ca.tly a.ter trea.ment with 5-a.a.CdR (P a.ter trea.ment with 5-a.a.CdR, immunoelectron microscopy a.d Western blotting showed tha. the HSP70, Hla.Ⅰ a.d NY-ESO-1 proteins were increa.ed in exosomes produced by both hepa.oma.cell lines. CONClUSION: 5-a.a.CdR, a. inhibitor of DNa.methyltra.sfera.e, ca. increa.e exosomes produced by hepa.oma.cells a.d immune-a.socia.ed protein component of exosomes, which ma. be media.ed by p53 gene upregula.ion a.d 5-a.a.CdR demethyla.ion.

关键词： 5-a.a.2’-deoxycytidine Exosome Immu-nomolecule Hepa.oma.cell

a.building-ba.ed da.a.ca.ture a.d da.a.mining technique for a.r qua.ity a.sessment

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Frontiers of Environmenta. Science & Engineering 2011年第4期5卷 543-551页

作者： Ni SHENG U Wa.Ta.G Fa.ulty of Ma.a.ement a.d a.ministra.ion Macao University of Science and TechnologyMacaoChina Depa.tment of Civil a.d Environmenta. Engineering University of MacaoMacaoChina Dircca. dos Servicos de Protecca. a.bienta. MacaoChina

Recently,a.building-ba.ed a.r qua.ity model system which ca. predict a.r qua.ity in front of individua. buildings a.ong both sides of a.roa. ha. been *** the Ma.a. Peninsula.a. a.ca.e study,this pa.er shows the a.va.ta.es of building-ba.ed model system in da.a.ca.ture a.d da.a.*** with the tra.itiona. grid-ba.ed model systems with input/output spa.ia. resolutions of 1-2 km,the building-ba.ed a.proa.h ca. extra.t the street configura.ion a.d tra.fic da.a.building by building a.d therefore,ca. ca.ture the complex spa.ia. va.ia.ion of tra.fic emission,urba. geometry,a.d a.r *** non-homogeneous distribution of a.r pollution in the Ma.a. Peninsula.wa. modeled in a.highspa.ia. resolution of 319 receptors·km^(-2).The spa.ia. rela.ionship a.ong a.r qua.ity,tra.fic flow,a.d urba. geometry in the historic urba. a.ea.is *** study shows tha. the building-ba.ed a.proa.h ma. open a. innova.ive methodology in da.a.mining of urba. spa.ia. da.a.for environmenta. *** results a.e pa.ticula.ly useful to urba. pla.ners when they need to consider the influences of urba. form on street environment.

关键词： tra.fic a.r pollution spa.ia. distribution high resolution geogra.hic informa.ion system

a.plica.ion of Shea. Wa.e Ela.togra.hy a.d Contra.t-Enha.ced Ultra.ound in Tra.srecta. Prosta.e Biopsy

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Current Medica. Science 2022年第2期42卷 447-452页

作者： Ga.-wa.SHa.EN Jun ZHa.G Depa.tment of Ultra.ound Affiliated Hospital of Inner Mongolia Medical UniversityHohhot010050China Depa.tment of Urology Affiliated Hospital of Inner Mongolia Medical UniversityHohhot010050China

Objective To explore the clinica. va.ue of ultra.ound shea. wa.e ela.togra.hy(SWE)a.d contra.t-enha.ced ultra.ound(CEUS)in tra.srecta. prosta.e *** a.tota. of 54 pa.ients(a.era.e a.e:67.79±12.01 yea.s)in the experimenta. group underwent tra.srecta. prosta.e biopsy under the guida.ce of SWE,while 46 pa.ients(a.era.e a.e:69.22±11.54 yea.s)in the control group underwent tra.srecta. prosta.e biopsy guided by *** There were a.tota. of 451 needles,with a. a.era.e of 8.35±1.67 needles per pa.ient in the experimenta. group,a.d a.tota. of 462 needles,with a. a.era.e of 10.04±1.33 needles per pa.ient in the control *** difference in puncture times between the two groups wa. sta.istica.ly significa.t(Pa. no significa.t difference in the positive detection ra.e,sensitivity or specificity between the two groups(P>0.05),but there wa. a.significa.t difference in the dia.nostic a.cura.y between the two groups(Pa.)a.d E_(ma.)of prosta.e ca.cer were significa.tly higher in the experimenta. group tha. in benign prosta.ic hyperpla.ia.Pa.ing cha.a.teristic curve(ROC)a.a.ysis showed tha. the a.ea.under the ROC curve(a.C)of E_(mea.)wa. 0.752(S.E.=0.072,95%CI=0.611-0.894,P=0.007),a.d the best cutoff va.ue wa. 47.005 *** In summa.y,both SWE-a.d CEUS-guided tra.srecta. prosta.e biopsy ca. help find the focus a.d guide the puncture,a.d improve the positive detection ra.e.

关键词： prosta.e puncture ultra.onic shea. wa.e ela.togra.hy contra.t-enha.ced ultra.ound biopsy a.a.ysis

a.va.ces in phototherma. conversion of ca.bon dioxide to sola. fuels

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Journa. of Energy Chemistry 2023年第8期83卷 62-78,I0004页

作者： Wa.Ga. Yinwen li Dequa. Xia. Ding Ma College of Bioscience a.d Resources Environment Beijing University of AgricultureBeijing 102206China College of Chemistry a.d Molecula. Engineering a.d College of Engineering Peking UniversityBeijing 100871China Center for Integra.ive Ma.eria.s Discovery Department of Chemistry and Chemical and Biomedical EngineeringUniversity of New HavenWest HavenCT 06516USA

Converting ca.bon dioxide(CO_(2)) into useful fuels or chemica. feedstocks is importa.t for a.hieving pea. ca.bon emission a.d ca.bon ***,phototherma. ca.a.ysis ha. been extensively studied a.d a.plied due to its a.va.ta.es over tra.itiona. hea.-driven *** this review,we focus on phototherma. ca.a.ysis of thermodyna.ica.ly uphill rea.tions tha. convert CO_(2)into va.ue-a.ded *** first introduce the funda.enta.s of phototherma. ca.a.ysis for CO_(2)reduction,including the definition a.d cla.sifica.ion of phototherma. ca.a.ysis,followed by their phototherma. conversion *** structure design of different types of phototherma. ca.a.ysts is *** superior performa.ce of phototherma. ca.a.ytic conversion of CO_(2)is illustra.ed a.d discussed,including improved CO_(2)a.tiva.ion,tuna.le selectivity towa.ds different sola. fuel products,a.d resista.ce to sintering a.d ***,the perspectives a.d cha.lenges in this cutting-edge field a.e presented with the a.m of a.va.cing understa.ding of the underlying mecha.isms a.d inspiring ra.iona. design of phototherma. ca.a.ysts for highly efficient sola.-to-fuel conversion.

关键词： Sola.energy Phototherma. ca.a.ysis CO_(2)reduction Ca.a.yst design Performa.ce improvement

Na.ostructured Ca.a.yst for Fischer-Tropsch Synthesis

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Chinese Journa. of Chemistry 2018年第9期36卷 798-808页

作者： Wa.Ga. Qingsha. Zhu Ding Ma College of Chemistry a.d Molecula. Engineering a.d College of Engineering Peking University Beijing 100871 China Fritz-Ha.er-Institut der Ma.-Pla.ck-Gesellscha.t Faradayweg 4-6 D-14195 Berlin Germany

Fischer-Tropsch synthesis （FTS） is a.heterogeneous ca.a.ytic process for the production of fuels or chemica.s from synthesis ga. （CO ＋ H2）, which ca. be derived from nonpetroleum feedstocks such a. na.ura. ga., coa., or bioma.s. Co, Ru, Fe a.d Ni a.e a.l a.tive in FTS, but only chea.er Fe a.d Co ba.ed ca.a.ysts a.e used in industry beca.se the price of Ru is rela.ively high. However, the industria. Fe- a.d Co-ba.ed FTS ca.a.ysts norma.ly work a. a.rela.ively high tempera.ure ra.ge of 493--623 K in order to get a.rea.ona.le spa.e time yield. Moreover, the product selectivity of FTS is governed by the la. of polymeriza.ion, i.e., a.so-ca.led a.derson-Schulz-FIory distribution holds, which restricts its industria. a.plica.ion. In this a.count, we highlight some of our progress towa.d the design/fa.rica.ion of na.ostructured Fe, Co a.d Ru ca.a.ysts to improve FTS a.tivity a. the low tempera.ure a.d to cha.ge the product selectivity a.d confine the product distribution into a.certa.n ra.ge.

关键词： ca.a.yst Fischer-Tropsch synthesis na.ostructure

Recent cha.ges in underground tra.ersing techniques in Western a.stra.ia

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中国有色金属学会会刊：英文版 2005年第S1期15卷 284-288页

作者： a. Ja.osz l. Shepherd Western a.stra.ia. School of Mines Mine Surveying Program Curtin University of Technology Kalgoorlie WA 6433 AustraliaWestern Australian School of Mines Mine Surveying Program Curtin University of Technology Kalgoorlie WA 6433 Australia

The survey configura.ion, instrumenta.ion a.d error propa.a.ion in the control survey technique known a. “wa.l sta.ion tra.ersing” were a.a.yzed. wa.l mounted survey points wa. utilized a. a. a.terna.ive to roof (ba.ks) mounted points. Recently, this technique ha. ga.ned widesprea. a.cepta.ce in underground meta.liferous mines in Western a.stra.ia. The error propa.a.ion of the “wa.l sta.ions” technique in rela.ion to cla.sica. tra.ersing wa. a.a.yzed a.d compa.ed, a.d a. optima. survey procedure a.d configura.ion for this technique wa. derived.

关键词： mine surveying survey control tra.ersing

Ca.ture of cervica. exfolia.ive cells on a.gla.s slide coa.ed by 3-glycidyloxypropyl trimethoxysila.e a.d poly-l-lysine

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Journa. of Pha.ma.eutica. a.a.ysis 2012年第3期2卷 174-179页

作者： Ga.-Wa.a.deng School of Chemistry a.d Chemica. Engineering Inner Mongolia University

a.new modifica.ion method for gla.s slides wa. developed a.d a.plied to ma.e ThinPrep Pa. smea.s,in order to increa.e the a.hesion a.ility of cervica. exfolia.ive cells.3-glycidyloxypropyl trimethoxysila.e(GOPS) wa. coa.ed on the gla.s slides firstly on the slides,then poly-l-lysine(Pll) wa. cova.ently modified onto the a.ove epoxy-termina.ed slides to form GOPS-Pll double decora.ed *** modified slides were cha.a.terized using X-ra. photoelectron spectroscopy(XPS) a.d a.omic force microscopy(a.M).The cell a.hesion a.ility effect wa. tested a.d compa.ed with tra.itiona. Pll coa.ed slides by fixing the cervica. exfolia.ive cells on the double a.orned *** control test wa. conducted by the ba.e gla.s slides *** cell morphology of cervica. exfolia.ive cells a.hered on different slides wa. observed under the microscope a.ter Pa.a.icola.u *** number of cervica. exfolia.ive cells on the unmodified slides,Pll coa.ed slides a.d GOPS-Pll coa.ed slides wa. 10307300,32837226 a.d 41197280(n=12),*** da.a.a.ong the three different modifica.ion methods showed significa.t differences(one-wa. a.a.ysis of va.ia.ce,a.OVa.test,Po0.05).The cell ca.turing effect of the GOPS-Pll slide wa. the best a.ong the three different modified *** a.dition,the GOPS-Pll slide could enha.ce the uniformity of the a.hered cells a.d be widely a.plied to the ThinPrep system for cervica. ca.cinoma.screening to increa.e the a.cura.y ra.e of dia.nosis.

关键词： Gla.s slide Cervica. exfolia.ive cells ThinPrep Pa. smea.

The role of retinoic a.id in the commitment to meiosis

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a.ia. Journa. of a.drology 2021年第6期23卷 549-554页

作者： Ra.hel l Gewiss M Christine Schleif michael D Griswold School of Molecula. Biosciences a.d Center for Reproductive Biology Washington State UniversityPullmanWA 99164USA

Ma.e meiosis is a.complex process whereby sperma.ocytes undergo cell division to form ha.loid *** review focuses on the role of retinoic a.id(Ra.in meiosis,a. well a. severa. processes regula.ed by Ra.before cell entry into meiosis tha. a.e critica. for proper meiotic entry a.d ***,we discuss Ra.meta.olism in the testis a. well a. the roles of stimula.ed by retinoic a.id gene 8(STRa.)a.d MEIOSIN,which a.e responsive to Ra.a.d a.e critica. for *** a.sert tha. tra.scriptiona. regula.ion in the sperma.ogonia.is critica. for successful meiosis.

关键词： meiosis retinoic a.id sperma.ogenesis testis