The role of retinoic acid in the commitment to meiosis
作者机构:School of Molecular Biosciences and Center for Reproductive BiologyWashington State UniversityPullmanWA 99164USA
出 版 物:《Asian Journal of Andrology》 (亚洲男性学杂志(英文版))
年 卷 期:2021年第23卷第6期
页 面:549-554页
核心收录:
学科分类:0710[理学-生物学] 07[理学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 090102[农学-作物遗传育种]
基 金:This work is supported by the National Institutes of Health(R01 HD10808 awarded to MDG)
主 题:meiosis retinoic acid spermatogenesis testis
摘 要:Male meiosis is a complex process whereby spermatocytes undergo cell division to form haploid *** review focuses on the role of retinoic acid(RA)in meiosis,as well as several processes regulated by RA before cell entry into meiosis that are critical for proper meiotic entry and ***,we discuss RA metabolism in the testis as well as the roles of stimulated by retinoic acid gene 8(STRA8)and MEIOSIN,which are responsive to RA and are critical for *** assert that transcriptional regulation in the spermatogonia is critical for successful meiosis.