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Nano Research 2024年第6期17卷 5604-5613页

作者： Huijun Kong Zhongqian Song meichun ding Changxiang Shao Jiahui Yu Baolei Wang Weiyan Li Chenwei Li Li Niu School of Chemistry and Pharmaceutical Engineering Shandong First Medical University and Shandong Academy of Medical SciencesJinan 250117China College of Artificial Intelligence and Big Data for Medical Sciences Shandong First Medical University and Shandong Academy of Medical SciencesJinan 250117China School of Chemical Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China

The issue of sensitivity attenuation in high-pressure region has been a persistent concern for pressure-sensitive electronic *** order to tackle such trade-off between sensitivity and linear range,herein,a hybrid piezoresistive-supercapacitive(HRSC)strategy is proposed via introducing a piezoresistive porous aerogel layer between the charge collecting electrodes and iontronic films of the pressure ***,the HRSC-induced impedance regulation and supercapacitive behavior contribute to significant mitigation in sensitivity attenuation,achieving high sensitivity across wide linear range(44.58 kPa^(−1)from 0 to 3 kPa and 23.6 kPa^(−1)from 3 to 12 kPa).The HRSC pressure sensor exhibits a low detection limit of 1 Pa,fast responsiveness(~130 ms),and excellent cycling stability,allowing to detect tiny pressure of air flow,finger bending,and human ***,the HRSC sensor exhibits exceptional perception capabilities for proximity and temperature,broadening its application scenarios in prosthetic perception and electronic *** proposed HRSC strategy may boost the ongoing research on structural design of high-performance and multimodal electronic sensors.

关键词： multimodal sensor pressure sensor high sensitivity MXene/poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)aerogel structural design

Highly efficient three-dimensional solar evaporator for zero liquid discharge desalination of high-salinity brine

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Carbon Energy 2024年第9期6卷 52-65页

作者： meichun ding Demin Zhao Panpan Feng Baolei Wang Zhenying Duan Rui Wei Yuxi Zhao Chen-Yang Liu Chenwei Li School of Chemistry and Pharmaceutical Engineering Shandong First Medical University&Shandong Academy of Medical SciencesJinanChina Medical Science and Technology Innovation Center Shandong First Medical University&Shandong Academy of Medical SciencesJinanChina Institut de Chimie Radicalaire Aix Marseille UniverisityMarseilleFrance CAS Key Laboratory of Engineering Plastics CAS Research/Education Center for Excellence in Molecular SciencesInstitute of Chemistrythe Chinese Academy of SciencesBeijingChina

Solar-driven interfacial evaporation is a promising technology for freshwater production from seawater,but salt accumulation on the evaporator surface hinders its performance and *** this study,we report a simple and green strategy to fabricate a three-dimensional porous graphene spiral roll(3GSR)that enables highly efficient solar evaporation,salt collection,and water production from near-saturated brine with zero liquid discharge(ZLD).The 3GSR design facilitates energy recovery,radial brine transport,and directional salt crystallization,thereby resulting in an ultrahigh evaporation rate of 9.05 kg m^(-2) h^(-1)6 in 25 wt%brine under 1-sun illumina-tion for 48 h ***,the directional salt crystallization on its outer surface not only enlarges the evaporation area but also achieves an ultrahigh salt collection rate of 2.92 kg m^(-2) h^(-1),thus enabling ZLD ***,3GSR exhibits a record-high water production rate of 3.14 kg m^(-2) h^(-1) in an outdoor *** innovative solution offers a highly efficient and continuous solar desalination method for water production and ZLD brine treatment,which has great implications for addressing global water scarcity and environmental issues arising from brine disposal.

关键词： graphene aerogels graphene composites solar desalination solar-driven interfacial evaporation

Preparation and Characterization of Nanocrystalline Cellulose/Poly(lactic acid) Composite Membranes

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Paper And Biomaterials 2017年第3期2卷 28-34页

作者： meichun ding ChenWei Li FuShan Chen College of Chemistry and Molecular Engineering Qingdao University of Science and TechnologyState Key Laboratory Base of Eco-chemical Engineering College of Materials Science and Engineering Laboratory of Fiber Materials and Modern TextileQingdao University

Nanocrystalline cellulose(NCC)/poly(lactic acid)(PLLA) composite membranes were prepared by the solution casting *** and chemical modifications were performed to improve the compatibility of NCC and *** results indicated that the NCC dispersibility of the composite membranes with chemical modification were superior to that of the composite membranes with physical ***,the chemical modification NCC not only had a large effect on the nucleation and growth of the crystals,but also affected the crystal forms of *** was because chemical reactions took place between the silicone of silane coupling agent(KH-570) and the hydroxyl groups of NCC during *** chemical modification NCC could be dispersed stably in the PLLA matrix,and it played the role of a nucleating agent.

关键词： NCC PLLA composite membranes modification

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GP分布模型与股票收益率分析

北京大学学报（自然科学版） 2000年第3期36卷 295-306页

作者：潘家柱丁美春北京大学数学学院金融数学系北京100871 北京大学数学学院概率统计系北京100871

讨论了GP分布模型的某些性质 ,利用此模型对上证指数、深证指数和 2家公司股票价格的收益率进行分析 ,给出股票指数和价格极值波动程度的量化指标和风险值 (VaR)的估计值。

关键词： GP分布收益率尾指数风险值证券市场股票

自我能力评估结合导师制带教模式在手术室新护士培养中的应用效果

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中西医结合护理（中英文） 2024年第5期10卷 186-188页

作者：赵云李梅春李静李娜丁璐蚌埠医学院第一附属医院安徽蚌埠233004

目的考察自我能力评估结合导师制带教模式在新护士培养中的应用效果。方法以2022年6~9月在蚌埠医学院第一附属医院手术室实习的63名新护士为对象开展研究,将其按照不同的培养方式进行分组,分别为对照组(31名)和观察组(32名)。对照组实... 详细信息

目的考察自我能力评估结合导师制带教模式在新护士培养中的应用效果。方法以2022年6~9月在蚌埠医学院第一附属医院手术室实习的63名新护士为对象开展研究,将其按照不同的培养方式进行分组,分别为对照组(31名)和观察组(32名)。对照组实施常规教学带教模式,观察组给予自我能力评估结合导师制带教模式。对2组的理论知识和临床实践操作成绩,以及人文关怀能力、评判性思维能力、职业认同感、护士核心能力和手术操作技能合格率进行比较。结果培养结束后,观察组的理论知识和临床实践操作成绩均高于对照组(P均<0.05)。培养后1个月和3个月,2组的人文关怀能力评价量表、中文版评判性思维量表(CTDI-CV)、职业认同感和护士核心能力评分与同组培养前相比均提高(P均<0.05);观察组的评分均高于同期对照组(P均<0.05)。观察组新护士的手术配合度、手术器械摆放和设备操作规范合格率均高于对照组(P均<0.05)。结论自我能力评估结合导师制带教模式可有效提高手术室新护士的理论知识和实践操作成绩,增强其人文关怀能力和护士核心能力,培养其职业认同感和批判性思维能力,且手术操作技能合格率更高。

关键词：新护士培养手术室导师制带教模式自我能力评估人文关怀能力

Fusobacterium nucleatum enhances the efficacy of PD-L1 blockade in colorectal cancer

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Signal Transduction and Targeted Therapy 2021年第12期6卷 3730-3739页

作者： Yaohui Gao Dexi Bi Ruting Xie Man Li Jing Guo Hu Liu Xianling Guo Juemin Fang Tingting ding Huiyuan Zhu Yuan Cao meichun Xing Jiayi Zheng Qing Xu Qian Xu Qing Wei Huanlong Qin Department of Pathology Shanghai Tenth People’s Hospital Affiliated to Tongji University200072 ShanghaiChina Department of Oncology Shanghai Tenth People’s Hospital Affiliated to Tongji University200072 ShanghaiChina Department of Gastrointestinal Surgery Shanghai Tenth People’s Hospital Affiliated to Tongji University200072 ShanghaiChina

Given that only a subset of patients with colorectal cancer(CRC)benefit from immune checkpoint therapy,efforts are ongoing to identify markers that predict immunotherapeutic *** evidence suggests that microbes influence the efficacy of cancer *** nucleatum induces different immune responses in CRC with different microsatellite-instability(MSI)***,we investigated the effect of *** on anti-PD-L1 therapy in *** found that high *** levels correlate with improved therapeutic responses to PD-1 blockade in patients with ***,*** enhanced the antitumor effects of PD-L1 blockade on CRC in mice and prolonged *** *** supplementation with immunotherapy rescued the therapeutic effects of PD-L1 ***,*** induced PD-L1 expression by activating STING signaling and increased the accumulation of interferon-gamma(IFN-γ)^(+)CD8^(+)tumor-infiltrating lymphocytes(TILs)during treatment with PD-L1 blockade,thereby augmenting tumor sensitivity to PD-L1 ***,patient-derived organoid models demonstrated that increased *** levels correlated with an improved therapeutic response to PD-L1 *** findings suggest that *** may modulate immune checkpoint therapy for CRC.

关键词： colorectal cancer interferon

新冠肺炎疫情防控背景下消毒产品监管法规概述

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中国洗涤用品工业 2020年第3期 90-94页

作者：丁春超思美春广州立白企业集团有限公司技术法规部广东广州510370 广州超威生物科技有限公司广东广州510370

消毒产品是防控传染病的重要物资之一,在我国消毒产品是由国家及地方卫生健康委员会监管的特殊产品,在监管过程中涉及到大量的法律、法规和标准要求,本文在新冠病毒疫情防控背景下,对消毒产品法规进行了整体梳理与综述,以期对行业同仁... 详细信息

消毒产品是防控传染病的重要物资之一,在我国消毒产品是由国家及地方卫生健康委员会监管的特殊产品,在监管过程中涉及到大量的法律、法规和标准要求,本文在新冠病毒疫情防控背景下,对消毒产品法规进行了整体梳理与综述,以期对行业同仁有所参考和借鉴。

关键词：消毒产品监管法规卫生许可证安全评价标签说明书

氢化物-原子荧光法测定食品容器及包装材料用聚酯树脂及其成型品中的微量锑

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广东微量元素科学 2011年第8期18卷 61-65页

作者：陈美春林舒忆丁枫芸杭州市质量技术监督检测院浙江杭州310019

为建立简便、快速、高效测定食品包装材料中微量锑的方法,样品用4%乙酸处理后,利用氢化物-原子荧光法检测食品包装材料中的微量锑。结果表明,锑质量浓度在0～20μg/L范围内呈现良好的线性,回归方程为y=87.284 C-17.440,相关系数r=0.999... 详细信息

为建立简便、快速、高效测定食品包装材料中微量锑的方法,样品用4%乙酸处理后,利用氢化物-原子荧光法检测食品包装材料中的微量锑。结果表明,锑质量浓度在0～20μg/L范围内呈现良好的线性,回归方程为y=87.284 C-17.440,相关系数r=0.999 9,检出限为0.028 4μg/L,相对标准偏差RSD为0.86%～4.04%,回收率91.5%～98.5%。该法具有快捷、灵敏度高、精密度好等优点。

关键词：锑氢化物-原子荧光法食品包装材料

Correction To: Fusobacterium nucleatum enhances the efficacy of PD-L1 blockade in colorectal cancer

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Signal Transduction and Targeted Therapy 2022年第1期7卷 333-333页

作者： Yaohui Gao Dexi Bi Ruting Xie Man Li Jing Guo Hu Liu Xianling Guo Juemin Fang Tingting ding Huiyuan Zhu Yuan Cao meichun Xing Jiayi Zheng Qing Xu Qian Xu Qing Wei Huanlong Qin Department of Pathology Shanghai Tenth People’s Hospital Affiliated to Tongji University 200072 Shanghai China Department of Oncology Shanghai Tenth People’s Hospital Affiliated to Tongji University 200072 Shanghai China Department of Gastrointestinal Surgery Shanghai Tenth People’s Hospital Affiliated to Tongji University 200072 Shanghai China

Correction to:Signal Transduction and Targeted Therapy https://***/10.1038/S41392-021-00795-x,published online 19 November 2021 In this article^(1) Qing Wei should have been denoted as a corresponding author along wit... 详细信息

关键词： colorectal process. removed

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在校护生人文关怀能力及影响因素调查

护理实践与研究 2022年第20期19卷 3034-3038页

作者：丁云霞席文娟徐叶果谭美春江西科技学院江西省南昌市330098

目的调查南昌市“护理专业大学生”(简称护生)人文关怀能力水平,分析其影响因素,为高校开展针对性的护理人文关怀教育提供参考。方法2021年6月对南昌市438名护生人文关怀能力水平进行问卷调查,对不同特征护生人文关怀能力进行比较和相... 详细信息

目的调查南昌市“护理专业大学生”(简称护生)人文关怀能力水平,分析其影响因素,为高校开展针对性的护理人文关怀教育提供参考。方法2021年6月对南昌市438名护生人文关怀能力水平进行问卷调查,对不同特征护生人文关怀能力进行比较和相关因素分析。结果护生人文关怀能力总分为173.46±19.24分。护生人文关怀知识主要来源为在校人文课程,且其学历层次、专业选择原因、专业喜爱度、人文相关概念认知、对今后发展的重要影响是人文关怀能力的主要影响因素(P<0.05)。结论护生人文关怀能力亟待提升,高校开展护理人文关怀教育需在丰富人文课程内容、教学方式、教学方法的基础上,分阶段循序渐进,多方位多措施并举进行改革。

关键词：护理专业大学生人文关怀能力影响因素人文关怀教育人文知识