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Analysis of Pedestrian Facilities in CBD Area of Pabna Municipality, Bangladesh

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Journal of Civil Engineering and Architecture 2017年第11期11卷 1025-1037页

作者： md. saiful islam md. Sohel Rana Department of Urban and Regional Planning Pabna University of Science and Technology Pabna 6600 Bangladesh

Pabna is one the most densely populated town with poor transport infrastructure in Bangladesh. Here huge pedestriangathers in roads and intersections in CBD （Central Business District） area mainly for commercial and business purposes. At present,pedestrian facilities are one of the greatest challenges in terms of traffic and safety for the urban dwellers. The footpath, zebra rossing,road intersection, walkways, parking and other facilities are the major part of road transportation system as well as pedestrianfacilities and people have to pass walking distance to reach their destinations, before and after use of transport mode. For instance,this paper tries to emphasize the problems of pedestrian facilities and to explore the qualitative level of comfort for the pedestrians ofthree selected intersections namely Traffic More, Indra More and Nimtola More in CBD area of Pabna Municipality through primaryand secondary data. However, about 60% trips are making on foot every day, but the pedestrians are facing many problems whileusing the walkways. Pedestrian crossing behaviors were also observed by using pedestrian volume survey and the survey exploresthat pedestrian crossing rate at these intersections is about 5,000 to 7,000 per hour at a peak period and average 15% to 25% illegalcrossing occurs at those intersections. The physical observation and data from the questionnaire survey also indicate that informalbusiness on the footpath, illegal parking, illegal vendor on walkways, physical obstacle, poor lighting facilities and geometricproblem of the road intersection makes uncomfortable situations for the pedestrian day by day.

关键词： Pedestrian facilities, traffic congestion, pedestrian crossing, CBD area, traffic volumes.

Prevalence and Characterization of Pathogens Responsible for Enteric Fever and Assessment of Their Antibiotic Susceptibility Pattern in Bangladesh

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Pharmacology & Pharmacy 2024年第9期15卷 303-313页

作者： Saima Mollick md. Jabir Hasnain md. saiful islam Tumpa Dasgupta Pharmaceutical Sciences Research Division BCSIR Laboratories Dhaka Bangladesh Council of Scientific and Industrial Research (BCSIR) Dhaka Bangladesh Directorate General of Drug Administration Dhaka Bangladesh Department of Clinical Pharmacy and Pharmacology Faculty of Pharmacy University of Dhaka Dhaka Bangladesh

In Bangladesh, Enteric fever is a persistent health issue throughout the year, occasionally reaching epidemic levels. The growing antibiotic resistance makes treatment increasingly challenging. Therefore, studying the antibiotic resistance patterns within the population is crucial to ensure a more effective treatment strategy. This study was designed to determine the prevalence, antimicrobial susceptibility profile, and factors associated with Salmonella spp. infections among clinically suspected Enteric fever patients in Bangladesh. This study also aimed to investigate whether there has been a re-emergence in the susceptibility of bacterial strains to conventional drugs. Data were collected from February 2024 to July 2024, from patients suspected Enteric fever (fever less than seven days duration) in a Private Diagnostic Center of Bangladesh. A total of 195 blood samples were cultured, where 53.85% came out positive, among which 79.05% Salmonella typhi and 20.95% Salmonella paratyphi A were found. Prevalence of Typhoid fever was observed high among the school-going age group (0 - 15 years) patients. Both these organisms were susceptible to ceftazidime, cefixime, ceftriaxone and cefepime but resistant to nalidixic acid, ciprofloxacin and levofloxacin. Nalidixic Acid is resistant to all S. paratyphi A and sensitive to few S. typhi. Ciprofloxacin and levofloxacin showed delayed response (36.14% and 22.72% sensitive to S. typhi and S. paratyphi A, respectively) and resistance (63.85% and 77.27% resistant to S. typhi and S. paratyphi A, respectively). In case of S. typhi, the resistance was found against ampicillin (32.53%), chloramphenicol (27.71%), cotrimoxazole (24.09%) and the resistance of S. paratyphi A found against ampicillin (4.54%), chloramphenicol (0%) and cotrimoxazole (0%). This study will provide clinicians with alternative drug options and facilitate the effective treatment of Enteric fever.

关键词： Typhoid Salmonella Nalidixic Acid Ciprofloxacin Chloramphenicol Cotrimoxazole

Comparison of Propofol and Fentanyl for Preventing Emergence Agitation Following Sevoflurane Anesthesia in Pediatric Patients: A Single-Center Study in Bangladesh

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Pharmacology & Pharmacy 2024年第6期15卷 223-235页

作者： md. saiful islam Khan md. Abir Tazim Chowdhury Farzana Fardousi Munama Magdum md. Ahaduzzaman Taneem Mohammad Shamima Akter Suriya Akter md. saiful islam Azad md. Mozaffer Hossain M. Abdur Rahman Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Bangladesh Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Bangladesh Department of Pathology National Institute of Cancer Research & Hospital Dhaka Bangladesh Department of Preventive and Social Medicine National Institute of Preventive and Social Medicine Dhaka Bangladesh Department of Anesthesia Sheikh Sayera Khatun Medical College Gopalgonj Bangladesh Department of Anesthesia Dhaka Medical College Dhaka Bangladesh Department of Anesthesia Combined Military Hospital Dhaka Bangladesh Department of Cardiac Anesthesia National Institute of Cardiovascular Disease Dhaka Bangladesh Department of Anesthesia Bangladesh Medical College Dhaka Bangladesh

Background: Emergence agitation (EA) is a common phenomenon observed in pediatric patients following general anesthesia. This study aimed to assess the efficacy of propofol and fentanyl in preventing EA and to compare their associated complications or side effects. Methods: This prospective randomized observational comparative study was conducted at Dhaka Medical College Hospital from July 2013 to June 2014. The study aimed to evaluate the effects of propofol and fentanyl on EA in children aged 18 to 72 months undergoing circumcision, herniotomy, and polypectomy operations. Ninety children were included in the study, with 45 in each group. Patients with psychological or neurological disorders were excluded. Various parameters including age, sex, weight, American Society of Anesthesiologists (ASA) class, duration of anesthesia, Saturation of Peripheral Oxygen (SPO2), heart rate (HR), respiratory rate (RR), Pediatric Anesthesia Emergence Delirium (PAED) score, duration of post-anesthesia care unit (PACU) stay, incidence of laryngospasm, nausea, vomiting, and rescue drug requirement were compared between the two groups. Results: Age, sex, weight, ASA class, and duration of anesthesia were comparable between the two groups. Perioperative SpO2 and HR were similar in both groups. However, the PAED score was significantly higher in the fentanyl group during all follow-ups except at 30 minutes postoperatively. The mean duration of PACU stay was significantly longer in the fentanyl group. Although the incidence of laryngospasm was higher in the fentanyl group, it was not statistically significant. Conversely, nausea or vomiting was significantly higher in the fentanyl group. The requirement for rescue drugs was significantly higher in the fentanyl group compared to the propofol group. Conclusion: Both propofol and fentanyl were effective in preventing emergence agitation in pediatric patients undergoing various surgical procedures under sevoflurane anesthesia. However, propo

关键词： Emergence Agitation (EA) General Anesthesia Propofol Fentanyl Pediatric Patients Pediatric Anesthesia Emergence Delirium (PAED) Score Bangladesh

The Relationship between Birds Diversity and Habitats in Phou Khao Khouay (PKK) National Park of Lao PDR

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Open Journal of Forestry 2019年第2期9卷 143-158页

作者： Phutpasong Thongsoulin Vichit Phanthuamath md. saiful islam Sithong Thongmanivong Yongxiang Kang Department of Ecology College of Forestry Northwest Agriculture and Forestry University Yangling China Faculty of Forestry National University of Lao PDR Vientiane Laos Ministry of Natural Resources and Environment Lao PDR Vientiane Laos Department of Basic Science Sheikh Fazilatunnesa Mujib Fisheries College Jamalpur Bangladesh

In recent years, global warming, drought and little rain, forest fires, forest destruction and other human disturbances have had an important impact on the habitat environment of birds, affecting the number and quality of bird habitats, directly threatening the survival and reproduction of birds, leading to a sharp decline in the diversity of bird species. In this study, the PKK National Park (18䓎' - 18䓠'N;102䓦' - 102䓻'E), Laos was used as a research site. The birds and their habitats in the park were used as research objects. The species, quantity and distribution of birds were investigated. In addition, the distribution of vegetation and the relationship between bird’s community and habitat types in PKK National Park were studied. Species diversity and Abundance of birds at PKK National Park, was monthly assessed by point count method between January and December 2018. A total of 117 species of birds belonging to 43 families and 18 orders were found in the inspection areas. Among them, Passerine birds (60 species) and Non-Finches (57 species) were almost equal to each other, accounting for 51.3% and 48.7% of total birds species respectively. Again, Anseriformes birds account for the largest number amongst Non-Passeriformes, reaching 15 species, followed by Falconiformes, accounting for 20.5% of total. On the other hand, based on migratory habits, resident birds were found to be highest in our research site which account for 35.04% of total birds and followed by Summer Migratory birds (32.28%), Passage Migrant (23.93%) and Winter Migratory birds (6.83%). Through the quantitative measurement and analysis of various parameters, the focus is on the diversity of birds and species in the park. Further, the factors that can affect species diversity, especially the bird’s survival factors such as vegetation change pattern, transformation rate of green areas, recruitment and restoration pattern of wild animals, especially birds, and other beneficial

关键词： Laos Bird Community Environment Habitat Diversity

Farmers’ Knowledge on Climate Change Effects in Agriculture

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Agricultural Sciences 2019年第3期10卷 386-394页

作者： md. saiful islam Muhammad Humayun Kabir md. Sekender Ali Mst. Sharmin Sultana Mohammad Mahasin Department of Agricultural Extension and Information System Sher-e-Bangla Agricultural University Dhaka Bangladesh

The major objectives of the study were to determine farmers’ knowledge on climate change effects in agriculture and to identify the factors that influenced farmers’ knowledge on climate change effects in agriculture. The study was conducted in four villages under Kazipur upazila of Sirajgonj district. Data were collected by using interview schedule from randomly selected 113 respondents during 1st January to 30th January, 2018. The findings revealed that an overwhelming majority (78.8%) of the respondents had medium to high knowledge on climate change effects in agriculture. Among eight selected characteristics, extension media contact, training received, organizational participation, and cosmopoliteness had significant positive contribution to the farmers’ knowledge on climate change effects in agriculture. It is recommended that to increase farmers’ knowledge on climate change effects initiative should be taken to improve farmers’ knowledge through more involving with organization, extension media and program.

关键词： Farmers Knowledge Climate Change Agriculture Bangladesh

Exploring the Role of Serum Cystatin C in Early Detection of Acute Kidney Injury among On-Pump Cardiac Surgery Patients: A Single-Center Investigation in Bangladesh

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World Journal of Cardiovascular Diseases 2024年第6期14卷 363-373页

作者： md. Ahaduzzaman md. Abir Tazim Chowdhury Munama Magdum md. saiful islam Khan Satyajit Sharma Monoj Tiwari md. Abul Bashar Maruf md. Alauddin Omar Sadeque Khan md. Mostafizur Rahman Mirza md. Nazmus Saquib Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Dhaka Bangladesh Department of Preventive and Social Medicine National Institute of Preventive and Social Medicine Dhaka Bangladesh Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Dhaka Bangladesh Department of Cardiac Surgery National Heart Foundation Hospital & Research Institute Dhaka Bangladesh Department of Cardiovascular and Thoracic Surgery B.P. Koirala Memorial Cancer Hospital Bharatpur Chitwan Nepal Department of Cardiac Surgery United Hospital Limited Dhaka Bangladesh Department of Cardiac Surgery Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Department of Cardiac Surgery Ibrahim Cardiac Hospital & Research Institute Dhaka Bangladesh

Background: Acute Kidney Injury (AKI) stands as a prominent postoperative complication in on-pump cardiac surgery, with repercussions on morbidity, mortality, and hospitalization duration. Current diagnostic criteria relying on serum creatinine levels exhibit a delayed identification of AKI, prompting an exploration of alternative biomarkers. Aims and Objectives: This study is designed to overcome diagnostic constraints and explore the viability of serum Cystatin C as an early predictor of Acute Kidney Injury (AKI) in individuals undergoing on-pump cardiac surgery. The investigation aims to establish the relationship between serum Cystatin C levels and the onset of AKI in patients subjected to on-pump cardiac surgery. Primary objectives involve the assessment of the diagnostic effectiveness of serum Cystatin C, its comparison with serum creatinine, and the exploration of its potential for the early identification and treatment of AKI. Methodology: Conducted as a single-center study at the cardiac surgery department of BSMMU in Bangladesh from September 2020 to August 2022, a comparative cross-sectional analysis involved 31 participants categorized into No AKI and AKI groups based on Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Data collection encompassed preoperative, post-CBP (cardiopulmonary bypass) conclusion at 2 hours, postoperative day 1, and postoperative day 2 intervals. Statistical analyses included Chi-squared tests, independent Student’s t-tests, and one-sample t-tests. Significance was set at P Results: The study revealed no significant differences in baseline characteristics between the No AKI and AKI groups, except for CPB time and cross-clamp time. Serum Cystatin C levels in the AKI group exhibited statistical significance at various time points, highlighting its potential as an early detector. Conversely, Serum Creatinine levels in the AKI group showed no statistical significance. The Receiver Operating Characteristic (ROC) curve analy

关键词： Acute Kidney Injury (AKI) On-Pump Cardiac Surgery Serum Cystatin C Serum Creatinine Diagnostic Biomarkers Early Detection Cardiopulmonary Bypass Single-Center Study Bangladesh

Antidiabetic Drugs in Combination with Hydroxychloroquine Improve Glycemic Control in Alloxan Induced Diabetic Rats

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Pharmacology & Pharmacy 2014年第7期5卷 725-735页

作者： Shaheda Zannah md. saiful islam A. F. M. Towheedur Rahman md. Asaduzzaman Abdul Alim Al Bari Yusuf Ali Gazi Jahirul islam A. H. M. Khurshid Alam Hazrat Ali Mamunur Rashid Department of Chemistry Khulna University of Engineering and Technology Khulna Bangladesh Department of Pharmacy University of Rajshahi Rajshahi Bangladesh

Worldwide prevalence of diabetes mellitus has become an issue of great concern in current decades. This life threatening disease is associated with worsening of glycemic control and progressive metabolic dysfunctions. Objective: Current study aimed to investigate the effect of hydroxychloroquine (HCQ) as an adjunct to glibenclamide or metformin on glycemic control in alloxan induced diabetic rats. Methods: HCQ was combined separately with two conventional anti-diabetic drugs;glibenclamide and metformin. At first, alloxan (120 mg/kg) induced diabetic rats were treated with single dose of metformin (850 mg/70 kg BW), glibenclamide (10 mg/70 kg BW) and HCQ (300 mg/70 kg BW) intraperitoneally once daily for two weeks. Then non fixed dose combinations of glibenclamide (5 mg/70 kg BW) with HCQ (150 mg/70 kg BW) and metformin (425 mg/70 kg BW) with HCQ (150 mg/70 kg BW) were injected along with those of the three drugs alone once daily for four weeks. Results: In alloxan induced diabetic rats, glibenclamide, metformin and their combination therapies reduced blood glucose level significantly but combination therapies are the most effective. Glibenclamide or metformin in combination with HCQ also significantly (P < 0.05) reduced the elevated levels of total cholesterol, triglycerides, and low density lipoprotein cholesterol (LDL-C) level and increased high density lipoprotein cholesterol (HDL-C) level. Moreover, HCQ potentiates the liver glycogen synthesis of metformin or glibenclamide. Conclusion: Outcomes of this investigation indicate that combination of glibenclamide or metformin with HCQ improves glycemic control and provides additional metabolic benefits, not achieved with either glibenclamide or metformin alone.

关键词： Diabetes Mellitus Glycemic Control HCQ Glibenclamide Metformin

Sensing and Uptake of Nitrogen in Rice Plant: A Molecular View

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Rice science 2019年第6期26卷 343-355页

作者： md.saiful islam Department of Soil Science Patuakhali Science and Technology University Graduate School of Agricultural and Life Sciences The University of Tokyo

As a main feature of plant autotrophy, assimilation of inorganic nitrogen (N) is not only of fundamental interest to the crop, but also a crucial factor in crop productivity. N is the main plant mineral nutrient needed for chlorophyll production and other plant cell components (proteins, nucleic acids and amino acids). I highlighted the novel aspects of N responsive sensors, transporters and signaling molecules recently identified in the monocot rice plant, and discussed their potential roles in N sensing and transporting. Furthermore, over the last couple of years, N sensing has been shown to be affected by different external factors, which act as local signals to trigger systemic signaling coordinated by long-distance transport or mobile signals in plant body. Understanding of this complex regulatory network provides a foundation mechanism for the development of novel strategies to increase the acquisition and transportation efficiency of nitrogen under varying N conditions for rice production.

关键词： rice nitrate signaling gene function

Cardio- and hepato-protective potential of methanolic extract of Syzygium cumini(L.) Skeels seeds:A diabetic rat model study

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Asian Pacific Journal of Tropical Biomedicine 2017年第2期7卷 126-133页

作者： Sumaiya Nahid Kishor Mazumd.r Zillur Rahman saiful islam md. Humayun Rashid Philip Grey Kerr Department of Pharmacy University of Science and Technology ChittagongFoy's LakePahartaliChittagong 4202Bangladesh School of Biomedical Sciences Charles Sturt UniversityBoorooma StreetWaggaWaggaNew South Wales 2678Australia Department of Pathology Chittagong Medical College HospitalChittagong 4202Bangladesh

Objective: To evaluate the effect of methanolic extract of Syzygium cumini(L.) Skeels(S. cumini) seeds on the major organs in an animal model of diabetes through biochemical and histopathological ***: The methanolic extracts of S. cumini seeds(100 and 200 mg/kg body weight) were administered to alloxan-induced diabetic rats daily, with fasting blood glucose levels being measured by glucometry at one-day interval for a duration of two weeks. Biochemical assays to evaluate changes in the functions of the heart, liver,pancreas and kidney were carried out. Histopathological changes in the diabetic rat organs(pancreas, liver, heart, kidney and spleen) were also observed after the 14 days of treatment with the ***: Oral administration of methanolic extracts of S. cumini seeds(100 and 200 mg/kg body weight), with gliclazide as a positive control(25 mg/kg), showed beneficial effects including lowering blood glucose levels(P < 0.001), improved heart and liver functions, and hyperlipidemia due to diabetes. At 200 mg/kg, the extracts reversed cardiac and liver damage caused by ***: In addition to the anti-hyperglycemic activity of methanolic extracts of S. cumini seeds, the extracts demonstrates potential to minimize cardiac and hepatic complications.

关键词： Syzygium cumini seeds Diabetes Cardioprotection Hepatoprotection