检索结果-南通市图书馆

Assessing the impact of concurrent high-fructose and highsaturated fat diets on pediatric metabolic syndrome:A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Pediatrics 2024年第2期13卷 62-79页

作者： Manuel Alejandro vargas-vargas Marcela González-Montoya Olin Torres-Isidro Claudia isabel García-Berumen Omar Ortiz-Avila Elizabeth Calderón-Cortés Christian Cortés-Rojo Instituto de Investigaciones Químico–Biológicas Universidad Michoacana de San Nicolás de HidalgoMorelia 58030MichoacánMexico Facultad de Enfermería Universidad Michoacana de San Nicolás de HidalgoMorelia 58020MichoacánMexico

High-saturated fat(HF)or high-fructose(HFr)consumption in children predispose them to metabolic syndrome(MetS).In rodent models of MetS,diets containing individually HF or HFr lead to a variable degree of ***,simultaneous intake of HF plus HFr have synergistic effects,worsening MetS *** children,the effects of HF or HFr intake usually have been addressed ***,we have reviewed the outcomes of HF or HFr diets in children,and we compare them with the effects reported in *** humans,HFr intake causes increased lipogenesis,hypertriglyceridemia,obesity and insulin *** the other hand,HF diets promote low grade-inflammation,obesity,insulin *** the deleterious effects of simultaneous HF plus HFr intake on MetS development in rodents,there is little information about the combined effects of HF plus HFr intake in *** aim of this review is to warn about this issue,as individually addressing the effects produced by HF or HFr may underestimate the severity of the outcomes of Western diet intake in the pediatric *** consider that this is an alarming issue that needs to be assessed,as the simultaneous intake of HF plus HFr is common on fast food menus.

关键词： Fructose Saturated fat Metabolic syndrome Insulin resistance Type 2 diabetes Ultra processed foods Children Obesity Dyslipidemia Non-alcoholic fatty liver disease

Hypersensitivity to Aspirin as a Factor for Poor Control in Hereditary Angioedema

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2017年第3期5卷 39-54页

作者： Carlos Alberto Garcia-Lopez maria Eugenia vargas-Camano Emmanuel Alcazar-Casarin Guillermo Quintana Mexiac Pablo Leon Gomez Mario Alberto Ynga-Durand Benjamin Lopez-Velazquez maria isabel Castrejon-Vazquez Servicio Inmunologia Clinica y Alergia Centro Medico Nacional“20 de Noviembre”ISSSTEMexico CityMexico Laboratorio de Inmunidad de Mucosas Seccion de Investigacion y PosgradoEscuela Superior de MedicinaInstituto Politecnico NacionalMexico CityMexico

Background: Hereditary angioedema (HAE) is a primary immunodeficiency disorder characterized by C1 complement inhibitor deficiency and unregulated activation of complement. Aspirin hypersensitivity is related to an increase in the amount of leukotrienes with eosinophil and mast cell activation and increased levels of glandular kallikrein with upregulated local conversion of bradykinin. Both conditions can be present in the same patient. Objectives: We present five patients with HAE;they were all being treated in similar ways according to the therapeuthic options available in our institute (danazol). However, three of them had recurrent episodes of angioedema;in these cases, it was identified aspirin hypersensitivity as a cause of poor disease control. A review of the literature is included. Case Presentation: We present the cases of four females and one male (age range 21 - 58 years) with type I HAE. Subjects were all ISSSTE beneficiaries (state workers) treated at the National Medical Center “20 de Noviembre”. Aspirin hypersensitivity was identified in three patients. Elimination of NSAIDs along with dietary elimination of high salicylate-containing foods improved control of angioedema crisis (severe and/ or recurrent episodes). Discussion: Aspirin hypersensitivity was identified as a factor for poor control in our patients with HAE. Such cases improved with dietary elimination of high salicylate-containing foods and avoidance of NSAIDs. Conclusions: This is the first report of patients with HAE and aspirin hypersensitivity as a cause of poor control. We recommend a deliberate search of these comorbidities, especially in cases of poor disease control. Further studies are needed to continue the investigation on this topic.

关键词： Hereditary Angioedema Immunodeficiency Complement Salicylates

Effects of occupational stress on the gastrointestinal tract

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Pathophysiology 2013年第4期4卷 108-118页

作者： María-Raquel Huerta-Franco Miguel vargas-Luna Paola Tienda isabel Delgadillo-Holtfort Marco Balleza-Ordaz Corina Flores-Hernandez Department of Applied Science and Labor Research DCS Campus LeonUniversity of Guanajuato Department of Physical Engineering DCICampus LeonUniversity of Guanajuato Loma del Bosque

The aim of this review is to provide a general overview of the relationship between occupational stress and gastrointestinal alterations. The International Labour Organization suggests occupational health includes psychological aspects to achieve mental well-being. However, the definition of health risks for an occupation includes biological, chemical, physical and ergonomic factors but does not address psychological stress or other affective disorders. Nevertheless, multiple investigations have studied occupational stress and its physiological consequences, focusing on specific risk groups and occupations considered stressful. Among the physiological effects of stress, gastrointestinal tract(GIT) alterations are highly prevalent. The relationship between occupational stress and GIT diseases is evident in everyday clinical practice; however, the usual strategy is to attack the effects but not the root of the problem. That is, in clinics, occupational stress is recognized as a source of GIT problems, but employers do not ascribe it enough importance as a risk factor, in general, and for gastrointestinal health, in particular. The identification, stratification, measurement and evaluation of stress and its associated corrective strategies, particularly for occupational stress, are important topics to address in the near future to establish the basis for considering stress as an important risk factor in occupational health.

关键词： Stress Occupation Gastric alterations Gastrointestinal tract diseases Health risks

The Secular Tendency of the Age at Menarche in a Representative Sample of Mexican Girls from an Urban Zone in Central Mexico

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Nutrition Sciences 2015年第15期6卷 1362-1370页

作者： María-Raquel Huerta-Franco Francisco-Miguel vargas-Luna Elba del Rosario Huerta-Franco Aminta Jimenez-Velazquez Marco Balleza isabel Delgadillo-Holford pplied Sciences to Work Department Division of Health Sciences Campus Leon University of Guanajuato Le&oacute n Mexico Engineering Physics Department Division of Science and Engineering Campus Leon University of Guanajuato Le&oacute n Mexico Dentistry Clinic of the University of Guadalajara Guadalajara Mexico Institute for Social Security and Services for the State Workers from Leon Guanajuato Mexico

Objective: To investigate the age at menarche, pubarche and telarche in a representative sample of residents of an urban zone of Leon, Guanajuato, Central Mexico and to evaluate the secular change of the age at menarche between 1985 and 2000. Methods: Using status quo and retrospective methods, menarcheal, pubarcheal and telarcheal status of girls 8 - 17 years of age (n = 1093) were determined. Multiple regression analysis and logistic regression were used to determine factors that were related to or predictive of age at menarche. Results: Median ages for menarche, pubarche and telarche in our studied sample were: 11.9 ± 0.04;11.13 ± 1.25 and 10.84 ± 1.34 years, respectively. A direct correlation was found between the age of menarche of adolescents and that of their mother (p p p = 0.001), but an indirect correlation was found with the girls’ hip circumference (p = 0.004). We demonstrated a clear secular tendency towards an earlier onset of menarche by comparing our results (11.9 ± 0.04) with data from 1985 (12.8 ± 1.3) for adolescents from the same city. Conclusion: We demonstrated a clear reduction in age at menarche of approximately 0.75 year/decade, higher than Tanner’s finding in 1962, but similar than that of Malina et al. in 2004.

关键词： Age at Menarche Adolescent Girls Secular Tendency

达比加群酯、利伐沙班或阿哌沙班与依诺肝素用于全髋关节或膝关节置换术后的血栓预防:系统综述、荟萃分析和间接治疗比较

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华关节外科杂志（电子版） 2013年第6期7卷 96-102页

作者： Antonio Gómez-Outes Ana isabel Terleira-Fernández M Luisa Suárez-Gea Emilio vargas-Castrillón Division of Pharmacology and Clinical Evaluation Medicines for Human UseSpanish Agency for Medicines and Medical DevicesParque Empresarial Las Mercedes Department of Clinical Pharmacology Hospital Clínico San Carlos

目的分析新型口服抗凝药预防全髋或全膝关节置换术后静脉血栓栓塞的临床转归.设计系统综述、荟萃分析以及间接治疗比较.数据来源 Medline和CENTRAL（至2011年4月为止）、临床试验注册中心、会议论文集以及药品监管机构的网站.研究选择... 详细信息

目的分析新型口服抗凝药预防全髋或全膝关节置换术后静脉血栓栓塞的临床转归.设计系统综述、荟萃分析以及间接治疗比较.数据来源 Medline和CENTRAL（至2011年4月为止）、临床试验注册中心、会议论文集以及药品监管机构的网站.研究选择利伐沙班、达比加群酯或阿哌沙班与依诺肝素相比,预防全髋或全膝关节置换术后静脉血栓栓塞症的随机对照试验.由两名研究者独立提取数据.采用随机效应荟萃分析估计症状性静脉血栓栓塞、临床相关出血、死亡和净临床终点（症状性静脉血栓栓塞、严重出血和死亡的复合转归）的相对危险度.分别使用RevMan和ITC软件进行直接和间接比较.结果共纳入16项试验,共计38 747例患者.与依诺肝素组相比,利伐沙班组（RR：0.48;95%CI：0.31～0.75）和阿哌沙班组（RR：0.82;95%CI：0.41～1.64）的症状性静脉血栓栓塞发生风险较低,达比加群酯组（RR：0.71;95%CI：0.23～2.12）.与依诺肝素组相比,利伐沙班组的临床相关出血相对危险度较高（RR：1.25;95%CI：1.05～1.49）,达比加群酯组与依诺肝素组相似（RR：1.12;95%CI：0.94～1.35）,而阿哌沙班组的相对危险度则较低（RR：0.82;95%CI：0.69～0.98）.直接和间接比较的结果显示,各种治疗的净临床终点均无差异.结论新型口服抗凝药的有效性较高,同时普遍有较高的出血倾向.新型口服抗凝药之间的有效性和安全性无显著差异.

关键词：全膝关节置换达比加群酯依诺肝素利伐沙班血栓预防全髋关节荟萃分析系统综述

门诊成人社区获得性肺炎的危险因素:生活方式和共病条件(NEUMO-ES-RISK项目)

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

英国医学杂志中文版 2019年第8期22卷 483-483页

作者： Irene Rivero-Calle Miriam Cebey-López Jacobo Pardo-Seco José Yuste Esther Redondo Diego A vargas Enrique Mascarós Jose Luis Díaz-Maroto Manuel Linares-Rufo isabel Jimeno Angel Gil Jesus Molina Daniel Ocana Federico Martinón-Torres 崔晓霞(译) 不详北京协和医院呼吸科

背景社区获得性肺炎(CAP)风险在初级保健中的信息是有限的。我们评估了不同生活方式和共病条件作为初级保健成人CAP的危险因素。方法一项回顾性观察对照研究。使用国家初级保健数据监测系统检索了2009至2013年在西班牙初级保健部门诊断... 详细信息

背景社区获得性肺炎(CAP)风险在初级保健中的信息是有限的。我们评估了不同生活方式和共病条件作为初级保健成人CAP的危险因素。方法一项回顾性观察对照研究。使用国家初级保健数据监测系统检索了2009至2013年在西班牙初级保健部门诊断的成人CAP病例。匹配年龄和匹配性别的对照组采用发病率密度抽样(比例2∶1)。以百分比和比值比来表示关联分析。为了避免偏倚效应,建立二项回归模型。结果51 139例患者和102 372例对照组做比较。平均年龄为61.4(19.9)岁。危险因素与CAP的显著相关性如下:艾滋病[比值比(95%可信区间)5.21(4.35~6.27)]、慢性阻塞性肺病(COPD)[2.97(2.84~3.12)]、哮喘[2.16(2.07~2.26)]、吸烟[1.96(1.91~2.02)]和口腔卫生问题[1.45(1.41~1.49)]。患者组中有危险因素存在的平均患病率为82.2%,对照组为69.2%。CAP患病率的增加与危险因素和年龄的累积有关:1个危险因素时,在18~60岁老人中的风险相关性是1.42,在>60岁人中是1.57;2个危险因素时,是1.88和2.35;≥3个危险因素时,是3.11和4.34。结论成人CAP初级保健中的危险因素普遍较高。主要与危险因素相关的是艾滋病、COPD、哮喘、吸烟、口腔卫生问题。我们的风险叠加结果可以帮助临床医生确定肺炎风险较高的患者。

关键词：社区获得性肺炎危险因素生活方式成人共病慢性阻塞性肺病初级保健门诊

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

集成电路电磁适应性的时钟信号调制(英文)

上海师范大学学报（自然科学版） 2010年第5期39卷 455-461页

作者：费利裴拉瓦迪蕾迪西亚波尔士法比安瓦嘎斯乔治赛米拉茱安安迪纳伊莎贝尔特谢拉保罗特谢拉格兰德天主教大学PUCRS 埃尔加夫大学INESC-ID 维果大学 IST INESC-ID

电磁干扰(EMI)是瞬时功能故障的主要来源之一,原因是电源供电线上的噪声注入引起了VDD和GND的额定值的波动.介绍了一种新的方法来增强片上系统(SoC)关于电源和接地电压瞬变时的信号完整性,并且这种方法完全符合IEC 61000—4—29标准.其... 详细信息

电磁干扰(EMI)是瞬时功能故障的主要来源之一,原因是电源供电线上的噪声注入引起了VDD和GND的额定值的波动.介绍了一种新的方法来增强片上系统(SoC)关于电源和接地电压瞬变时的信号完整性,并且这种方法完全符合IEC 61000—4—29标准.其基本思想是设计和IEC 61000—4—29兼容的集成电路,通过局部和动态地将时钟占空比去适应传播延迟的变化和扰动的逻辑路径.当无法满足时,该方法导致暂时把集成电路的工作频率减小到满足该标准的最小值.根据异常电网活动,时钟占空比调制(CDCM)是通过使用正和/或负边沿时钟展宽逻辑(CSL)块来实现的.基于这个概念,在尽可能保持时钟高速频率的同时,数字电路对于电源供电线上波动的耐受性将会更强.该方法可被视作一种在线提供动态自适应同步的监视技术.通过SPICE模拟,实验结果表明此方法的有效性.

关键词：信号完整性 IEC 61000—4—29 集成电路