检索结果-南通市图书馆

A comprehensive review of genetic causes of obesity

World Journal of Pediatrics 2024年第1期20卷 26-39页

作者： Marcio Jose Concepcion-Zavaleta Juan Eduardo Quiroz-Aldave maria del carmen durand-vasquez Elman Rolando Gamarra-Osorio Juan del carmen Valencia de la Cruz Claudia Mercedes Barrueto-Callirgos Susan Luciana Puelles-Leon Elena de Jesus Alvarado-Leon Frans Leiva-Cabrera Francisca Elena Zavaleta-Gutierrez Luis Alberto Concepcion-Urteaga Jose Paz-Ibarra Universidad Cientifica del Sur Bolivar 2150 AvenuePueblo Libre15084LimaPeru Division of Medicine Hospital de Apoyo ChepénChepenPeru Division of Family Medicine Hospital de Apoyo ChepénChepenPeru Division of Endocrinology Hospital Victor Lazarte EchegarayTrujilloPeru Division of Pediatrics Hospital de Apoyo ChepenChepenPeru Division of Internal Medicine Hospital de Apoyo ChepenChepenPeru Division of Genetics Universidad Nacional de TrujilloTrujilloPeru Division of Neonatology Hospital Belen de TrujilloTrujilloPeru Division of Internal Medicine Universidad Nacional de TrujilloTrujilloPeru Department of Medicine School of MedicineUniversidad Nacional Mayor de San MarcosLimaPeru

Background Obesity is a multifactorial chronic disease with a high,increasing worldwide *** causes account for 7%of the cases in children with extreme *** sources This narrative review was conducted by searching for papers published in the PubMed/MEDLINE,Embase and SciELO databases and included 161 *** search used the following search terms:"obesity","obesity and genetics","leptin","Prader-Willi syndrome",and"melanocortins".The types of studies included were systematic reviews,clinical trials,prospective cohort studies,cross-sectional and prospective studies,narrative reviews,and case *** The leptin-melanocortin pathway is primarily responsible for the regulation of appetite and body ***,several important aspects of the pathophysiology of obesity remain *** causes of obesity can be grouped into syndromic,monogenic,and polygenic causes and should be assessed in children with extreme obesity before the age of 5 years,hyperphagia,or a family history of extreme obesity.A microarray study,an analysis of the melanocortin type 4 receptor gene mutations and leptin levels should be performed for this *** are three therapeutic levels:lifestyle modifications,pharmacological treatment,and bariatric *** Genetic study technologies are in constant development;however,we are still far from having a personalized approach to genetic causes of obesity.A significant proportion of the affected individuals are associated with genetic causes;however,there are still barriers to its approach,as it continues to be underdiagnosed.

关键词： Leptin Melanocortin Obesity Prader-Willi syndrome Precision medicine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical site infection following pancreaticoduodenectomy in a referral cancer center in Mexico

引用

Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 502-508页

作者： Rodrigo Villaseñor-Echavarri Javier Melchor-Ruan Mercedes Aranda-Audelo Gabriela Arredondo-Saldaña Patricia Volkow-Fernandez maria del carmen Manzano-Robleda Alejandro E Padilla-Rosciano Diana Vilar-Compte Department of Infectious Diseases Instituto Nacional de CancerologíaAv.San Fernando 22Belisario Domínguez Secc 16TlalpanMexico CityMexico School of Medicine Universidad PanamericanaAugusto Rodin No.498Insurgentes MixcoacBenito JuárezMexico CityMexico Department of Digestive Tube and Hepatopancreatobiliary Tumors Instituto Nacional de CancerologíaAv.San Fernando 22Belisario Domínguez Secc 16TlalpanMexico CityMexico Department of Infectious Diseases Hospital Manuel Gea GonzálezCalz.de Tlalpan 4800Belisario Domínguez Secc 16TlalpanMexico CityMexico Gastrointestinal and Endoscopy Department Instituto Nacional de CancerologíaAv.San Fernando 22Belisario Domínguez Secc 16TlalpanMexico CityMexico

Background: Pancreaticoduodenectomy is the standard treatment for resectable periampullary cancer. Surgical site infections(SSI) are common complications with increased morbidity. The study aimed to describe the prevalence, risk factors, microbiology, and outcomes of SSI among patients undergoing pancreaticoduodenectomy. Methods: We conducted a retrospective study in a referral cancer center between January 2015 and June 2021. We analyzed baseline patient characteristics and SSI occurrence. Culture results and susceptibility patterns were described. Multivariate logistic regression was used to determine risk factors, proportional hazards model to evaluate mortality, and Kaplan-Meier analysis to assess long-term survival. Results: A total of 219 patients were enrolled in the study;101(46%) developed SSI. Independent factors for SSI were diabetes mellitus, preoperative albumin level, biliary drainage, biliary prostheses, and clinically relevant postoperative pancreatic fistula. The main pathogens were Enterobacteria and Enterococci. Multidrug-resistance rate in SSI was high but not associated with increased mortality. Infected patients had higher odds of sepsis, longer hospital stay and intensive care unit stay, and readmission rate. Neither 30-day mortality nor long-term survival was significantly different between infected and non-infected patients. Conclusions: SSI prevalence among patients undergoing pancreaticoduodenectomy was high and largely caused by resistant microorganisms. Most risk factors were related to preoperative instrumentation of the biliary tree. SSI was associated with greater risk of unfavorable outcomes;however, survival was unaffected.

关键词： Surgical site infection Pancreaticoduodenectomy Pancreatic cancer Endoscopic biliary drainage Biliary prosthesis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

From liver to hormones:The endocrine consequences of cirrhosis

引用

World Journal of Gastroenterology 2024年第9期30卷 1073-1095页

作者： Juan Eduardo Quiroz-Aldave Elman Rolando Gamarra-Osorio María del carmen durand-Vásquez Luciana del Pilar Rafael-Robles Jhean Gabriel Gonzáles-Yovera María Alejandra Quispe-Flores Luis Alberto Concepción-Urteaga Alejandro Román-González José Paz-Ibarra Marcio José Concepción-Zavaleta Non-communicable Diseases Endocrinology Research LineHospital de Apoyo ChepénChepén 13871Peru Department of Endocrinology Hospital Víctor Lazarte EchegarayTrujillo 13006Peru Department of Endocrinology Clínica Javier PradoLima 15046Peru Department of Gastroenterology Hospital Nacional Guillermo Almenara IrigoyénLima 15018Peru Department of Endocrinology Hospital de Emergencias GrauLima 15001Peru Internal Medicine Hospital Regional Docente de TrujilloTrujillo 13011Peru Department of Endocrinology Hospital Universitario de San Vicente FundaciónMedellin 050010Colombia Internal Medicine Universidad de AntioquiaMedellín 050010Colombia School of Medicine Universidad Nacional Mayor de San MarcosLima 15081Peru Department of Endocrinology Hospital Nacional Edgardo Rebagliati MartinsLima 15072Peru Carrera de Medicina Humana Universidad Científica del SurLima 15067Peru

Hepatocrinology explores the intricate relationship between liver function and the endocrine *** liver diseases such as liver cirrhosis can cause endocrine disorders due to toxin accumulation and protein synthesis *** its importance,assessing endocrine issues in cirrhotic patients is frequently *** article provides a comprehensive review of the epidemiology,pathophysiology,diagnosis,and treatment of endocrine disturbances in liver *** review was conducted using the PubMed/Medline,EMBASE,and Scielo databases,encompassing 172 *** cirrhosis is associated with endocrine disturbances,including diabetes,hypoglycemia,sarcopenia,thyroid dysfunction,hypogonadotropic hypogonadism,bone disease,adrenal insufficiency,growth hormone dysfunction,and secondary *** optimal tools for diagnosing diabetes and detecting hypoglycemia are the oral glucose tolerance test and continuous glucose monitoring system,*** can be assessed through imaging and functional tests,while other endocrine disorders are evaluated using hormonal assays and imaging *** options include metformin,glucagon-like peptide-1 analogs,sodium-glucose co-transporter-2 inhibitors,and insulin,which are effective and safe for diabetes *** standards are followed for managing hypoglycemia,and hormone replacement therapy is often necessary for other endocrine *** transplantation can address some of these problems.

关键词： Diabetes mellitus Hypoglycemia Thyroid diseases Hypogonadism Metabolic bone diseases Liver cirrhosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bowman-Birk inhibitors from legumes as colorectal chemopreventive agents

引用

World Journal of Gastroenterology 2014年第30期20卷 10305-10315页

作者： Alfonso Clemente maria del carmen Arques Department of Physiology and Biochemistry of Nutrition Estación Experimental del Zaidín (CSIC)18008 GranadaSpain

Aberrant functioning of serine proteases in inflammatory and carcinogenic processes within the gastrointestinal tract(GIT)has prompted scientists to investigate the potential of serine protease inhibitors,both natural and synthetic,as modulators of their proteolytic *** inhibitors of the Bowman-Birk type,a major protease inhibitor family in legume seeds,which inhibit potently and specifically trypsin-and chymotrypsin-like proteases,are currently being investigated as colorectal chemopreventive *** relevant amounts of Bowman-Birk inhibitors(BBI)can reach the large intestine in active form due to their extraordinary resistance to extreme conditions within the *** in animal models have proven that dietary BBI from several legume sources,including soybean,pea,lentil and chickpea,can prevent or suppress carcinogenic and inflammatory processes within the *** the therapeutic targets and the action mechanism of BBI have not yet been elucidated,the emerging evidence suggests that BBI exert their preventive properties via protease inhibition;in this sense,serine proteases should be considered as primary targets in early stages of *** validation of candidate serine proteases as therapeutic targets together with the identification,within the wide array of natural BBI variants,of the most potent and specific protease inhibitors,are necessary to better understand the potential of this protein family as colorectal chemopreventive agents.

关键词： Bowman-Birk inhibitors Cell proliferation Chemoprevention Colorectal cancer Legumes Serine proteases

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaluation of ^(177)Lu-Dotatate treatment in patients with metastatic neuroendocrine tumors and prognostic factors

引用

World Journal of Gastroenterology 2020年第13期26卷 1513-1524页

作者： Estephany Abou Jokh Casas Virginia Pubul Núnez Urbano Anido-Herranz María del carmen Mallón Araujo maria del carmen Pombo Pasín Miguel Garrido Pumar José Manuel Cabezas Agrícola José Manuel Cameselle-Teijeiro Ashraf Hilal álvaro Ruibal Morell Department of Nuclear Medicine Santiago de Compostela′s University HospitalSantiago de Compostela 15706A CorunaSpain Department of Oncology Santiago de Compostela′s University HospitalSantiago de Compostela 15706A CorunaSpain Department of Endocrinology Santiago de Compostela′s University HospitalSantiago de Compostela15706A CorunaSpain Department of Pathology Santiago de Compostela′s University HospitalSantiago de Compostela 15706A CorunaSpain Department of Statistics University of Santiago de CompostelaSantiago de Compostela 15706A CorunaSpain

BACKGROUND^177Lu peptide receptor radionuclide therapy(PRRT)is a recently approved therapy in Spain that has been demonstrated to be a well-tolerated therapy for positive somatostatin receptor advanced gastroenteropancreatic neuroendocrine *** To determine the impact of PRRT on quality of life,radiologic and metabolic response,overall survival,prognostic factors and *** Thirty-six patients treated with^177Lu-PRRT from 2016 to 2019 were *** most frequent location of the primary tumor was the gastrointestinal tract(52.8%),pancreas(27.8%),and nongastropancreatic neuroendocrine tumor(11.1%).The liver was the most common site of metastasis(91.7%),followed by distant nodes(50.0%),bone(27.8%),peritoneum(25.0%)and lung(11.1%).Toxicity was evaluated after the administration of each *** efficacywas evaluated by two parameters:stable disease and disease progression in response evaluation criteria in solid tumors 1.1 criterion and prognostic factors were *** From 36 patients,55.6%were men,with a median age of 61.1±11.8 *** previous treatments,55.6%of patients underwent surgery of the primary tumor,100%of patients were treated with long-acting somatostatin analogues,66.7%of patients were treated with everolimus,27.8%of patients were treated with tyrosine kinase inhibitor,and 27.8%of patients were treated with *** patient received radioembolization,three patients received chemoembolization,six patients received *** toxicity was registered in 14 patients(G1-G2:55.5%and G3:3.1%).Other events presented were intestinal suboclusion in 4 cases,cholestasis in 2 cases and carcinoid crisis in 1 *** median follow-up time was 3 ***,24 patients completed *** are alive with stable disease,two have disease progression,eight have died,and nine are still receiving *** median overall survival was 12.5 mo(95%confidence interval range:9.8–15.2),being inversely p

关键词： Peptide receptor radionuclide therapy Gastropancreatic neuroendocrine tumors Radiological response Metabolic response

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Determination of Mercuric Ion in Water Samples with a LED Exciting and CCD Based Portable Spectrofluorimeter

引用

American Journal of Analytical Chemistry 2011年第5期2卷 605-611页

作者： Arsenio Munoz de la Pena maria Isabel Rodriguez-Caceres Diego Bohoyo Gil maria del carmen Mahedero maria del carmen Hurtado-Sanchez Reyes Babiano Department of Analytical Chemistry University of ExtremaduraBadajozSpain Department of Organic and Inorganic Chemistry University of ExtremaduraBadajozSpain

The fluorescent characteristics of a fluorimetric chemosensor for mercuric ion, Hg2+, employing a synthesized Rhodamine 6G derivative, have been analyzed. For that, a portable spectrofluorimeter composed of a 515 nm LED as excitation source, two fiber-optics and a CCD camera as detector, has been used, intended for “in situ” analysis. A highly selective Rhodamine based probe for Hg2+, that is water soluble and gives a positive response upon analyte binding, is reported. The reagent is bearing a monothiospirolactone group in a Rhodamine 6G architecture and the thiol atom served for the direct attack of thiophilic Hg2+. The fluorescence enhancement is attributed to the spirolactone ring opening and the coordination of two sulphur atoms to Hg2+ giving a 2:1 reagent: Hg2+ stoichiometry complex.

关键词： Chemosensor LED Mercuric Ion Water Analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Structural Bioinformatics of Protein &DNA, as Early Stimulation in Basic Education of Rural and Indigenous Communities of Oaxaca

引用

Engineering（科研） 2013年第10期5卷 255-258页

作者： Susana Lozano-Muniz maria del carmen Urzua-Hernandez Biotechnology Institute Universidad del Papaloapan Tuxtepec Mexico International Foundation for Biotechnology Research & Early Stimulation in the Culture of Health Nutrition Sport Art Science Technology & Society A.C. San Juan Bautista Tuxtepec Mexico International Foundation for Biotechnology Research & Early Stimulation in the Culture of Health Nutrition Sport Art Science Technology & Society A.C. San Juan Bautista Tuxtepec Mexico Facultad de Quimica Universidad Nacional Autonoma de Mexico Ciudad de México Mexico

As stated in the Declaration of the Rights of the Child, children have the right to go to school for free, to play, and to have the same opportunity to develop and to learn to be responsible and useful[1]. Young children are curious by nature and they have passion for learning [2]. An environment that encourages scientific thinking is what gives young children the time, space and materials to exercise their curiosity [3]. The aim of this paper is to present a methodology for the development of educational environments based on digital technology, internet and free programs available on the web, for the use and application of structural bioinformatics protein and DNA, for early stimulation in basic education at rural and indigenous communities in state of Oaxaca, conducted in On Line Learning & Training “OLL & T”. The course is divided into 4 sections: 1)Introduction to the topic of protein and DNA structure;2)Search in protein data bank;3)Download RasTop program and use it as bioinformatics tool;4)Emulation of building a viral molecule. Workshops were given to children in elementary, middle and high school at the Universidad del Papaloapan during the National Week of Science and Technology, every year in Oaxaca since 2007 to 2012 and in Monterrey 2010 at the Universidad Autonoma de Nuevo León. Conclusions: positive impact was achieved in basic education in the area of natural sciences by analyzing the molecular basis of protein and deoxyribonucleic acid, theoretically and practically, as a support for teachers.

关键词： TICs Childhood Improvement Achievement

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preliminary Studies on Composition, Quality and Oxidative Stability of Commercial Avocado Oil Produced in Chile

引用

Journal of Food Science and Engineering 2014年第1期4卷 21-26页

作者： Marcos Alexis Flores maria del carmen Perez-Camino Jose Troca Basic Science Department Faculty of Science University of Santo Tom6s Avda. Carlos Schorr 255 Talca 3473620 Chile Instituto de la Grasa (CSIC) Avda. Padre Tejero 4 Seville 41012 Spain

Avocado oil is a relatively new oil in the market and is highly appreciated by the consumers because of its fine aroma, pleasant taste and health benefits. A study on the characterization of commercial avocado oils produced in Chile was conducted in order to discuss their quality parameters. The study was applied to two marketed avocado oils. The main analytical parameters evaluated to the oils were： fatty acid composition, total chlorophylls, total carotenoids, tocopherols, acid value, peroxide value, total phenolic compounds, polar compounds, oil stability, UV absorption and 3.5-stigmastadiene content. The fatty acid compositions of the studied oils were according with oil composition of pulp pure of avocado fruit. The analysis of tocopherols by high performance liquid chromatography （HPLC） revealed significant differences between the avocado oils studied. Total phenolic compounds, oil stability, UV Absorption characteristics, peroxide value, acid value, tocopherols content, total chlorophylls, total carotenoids and polar compounds were also significantly different between the commercial studied oils. All the above results show a different quality between both commercial avocado oils, showing that the sample C has worse values for the parameters of quality as those required by legislation in many countries. Also, 3.5-stigmastadiene content shows high concentration for one of the commercial avocado oil evaluated which demonstrates the presence of refined oil or that the oil has been submitted to high temperatures. On the other hand it is remarkable that despite the fact that there are many differences in quality parameters, both oils are labeled and marketed as extra virgin quality oils, demonstrating the need to regulate the classification of appreciated oils by the consumers.

关键词： Avocado oil 3.5-estigmastadiene polar compounds quality parameters.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

电子商务门户UI/UX策略基于中国消费者的行为

电子商务门户UI/UX策略基于中国消费者的行为

引用

作者： maria del carmen Sofia Carbajal Montero 北京外国语大学

学位级别：硕士

电子商务入口网站是数字化背景下跨境商务得以实现的要素并且逐渐成为了关键性的销售渠道,供全球各地的公司借以招徕在线客户。公司,特别是零售商的这些触点研究所产生的影响,推动了作为技巧的范式的变革,因为用户界面和用户体验对于电... 详细信息

电子商务入口网站是数字化背景下跨境商务得以实现的要素并且逐渐成为了关键性的销售渠道,供全球各地的公司借以招徕在线客户。公司,特别是零售商的这些触点研究所产生的影响,推动了作为技巧的范式的变革,因为用户界面和用户体验对于电子商务平台的建设、定制和持续促进都对十分必要的。虽然电子商务平台使得公司能够进行跨国售卖。文化会对市场的诸多特异性产生影响,也会对用户在线购物的方式产生影响。在此背景下,本文对现有的对中国电子商务进行的研究实施分析,这些研究大部分都与此类服务的应用有关。同时本文还将对消费者行为的文化层面探究,从不同的角度对这样的应用进行讨论。为对消费者行为进行解释,一项调查对中国和欧洲的电子商务应用状况进行了研究,尝试判定消费者消费过程中最为重要的消费者体验要素。笔者对三个不同群体的观点进行了对比:第一种,生活于中国的中国学生与年轻职员;第二种,两所意大利大学的东方研究学院毕业生;第三种,生活于中国但来自其他不同国家的年轻学生与职员。这些研究的主要观点是社会互动是在中国市场中建立电子商务网站的关键要素。这一趋势在新一代群体中尤为明显,因此对这一发现进行应用能够确保针对中国客户的(?)户网站的成功建立。调查结果与该课题资深人员的观点为我们提供了必要的信息,使我们能够针对设计框架实施可用性测试,从而以社会互动为用户体验核心进行考量,并最终将结果纳入对于西方电子商务向中国市场提供的体验的分析。可用性实验在伦敦针对一组亚洲学生进行,由于实验对象对两种内户网站范式(西方与中国)都很熟悉,因此我们得到了非常有趣的结果。这一研究具有较好的实用性并能够很方便地获得分析工具从而实施可用性分析,以确保满足文化本土化和该市场下未来用户的需求,从而为未来此方面的研究提供参考。用户体验人员、网页设计师、业务分析师、产品经理/所有者都能够以本文研究为参考,进行以用户为中心的研究。因此,本研究突出了针对中国用户的(?)户网站中集体取向的影响,为针对中国市场进行电子商务开发提供了全面的特征或行为以供参考。无论其可行性如何,其优化应用将不仅依赖于创新设计的使用,同时还会受到社会互动对于进行更高可能性会话推送的推荐算法的影响的左右。

关键词：电子商务跨境研究用户界面/用户体验互动电子商务集体取向

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Lack of functional link in the tadpole morphology induced by predators

引用

Current Zoology 2016年第3期62卷 227-235页

作者： maria Gabriela PEROTTI mariana PUETA Fabian Gaston JARA carmen Adria UBED Debora Lina MORENO AZOCAR Laboratorio de Fotobiologfa INIBIOMA CONICET-Universidad Nacional del Comahue O.uintral 1250 Bariloche Rio Negro Argentina Departamento de Biologfa General. Universidad Nacional del Comahue Quintral 1250 Bariloche Rio Negro Argentina Departamento de Zoologia INIBIOMA CONICET-Universidad Nacional del Comahue Quintral 1250 8400 Bariloche Rio Negro Argentina

Most studies of predator-induced plasticity have focused on documenting how prey species re- spond to predators by modifying phenotypic traits and how traits correlate with fitness. We have previously shown that Pleurodema thaul tadpoles exposed to the dragonfly Rhionaeschna varie- gata responded strongly by showing morphological changes, less activity, and better survival than non-exposed tadpoles. Here, we tested whether there is a functional link between morphological plasticity and increased survival in the presence of predators. Tadpoles that experienced predation risk were smaller, less developed, and much less active than tadpoles without this experience. Burst speed did not correlate significantly with morphological changes and predator-induced deeper tails did not act as a lure to divert predator strikes away from the head. Although we have previously found that tadpoles with predator-induced morphology survive better under a direct predator threat, our results on the functional link between morphology and fitness are not conclu- sive. Our results suggest that in P. thaultadpoles （1） burst speed is not important to evade preda- tors, （2） those exposed to predators reduce their activity, and （3） morphological changes do not divert predator attacks away from areas that compromise tadpole survivalEE. Our results show that morphological changes in P. thaul tadpoles do not explain burst speed or lure attraction, al- though there was a clear reduction of activity, which itself reduces predation. We propose that changes in tadpole activity could be further analyzed from another perspective, with morphological change as an indirect product of behavior mediated by physiological mechanisms.

关键词： induced morphology lure effect predator exposure swimming performance tadpoles.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：