From liver to hormones:The endocrine consequences of cirrhosis

作     者：Juan Eduardo Quiroz-Aldave Elman Rolando Gamarra-Osorio María del Carmen Durand-Vásquez Luciana del Pilar Rafael-Robles Jhean Gabriel Gonzáles-Yovera María Alejandra Quispe-Flores Luis Alberto Concepción-Urteaga Alejandro Román-González José Paz-Ibarra Marcio José Concepción-Zavaleta 

作者机构：Non-communicable DiseasesEndocrinology Research LineHospital de Apoyo ChepénChepén 13871Peru Department of EndocrinologyHospital Víctor Lazarte EchegarayTrujillo 13006Peru Department of EndocrinologyClínica Javier PradoLima 15046Peru Department of GastroenterologyHospital Nacional Guillermo Almenara IrigoyénLima 15018Peru Department of EndocrinologyHospital de Emergencias GrauLima 15001Peru Internal MedicineHospital Regional Docente de TrujilloTrujillo 13011Peru Department of EndocrinologyHospital Universitario de San Vicente FundaciónMedellin 050010Colombia Internal MedicineUniversidad de AntioquiaMedellín 050010Colombia School of MedicineUniversidad Nacional Mayor de San MarcosLima 15081Peru Department of EndocrinologyHospital Nacional Edgardo Rebagliati MartinsLima 15072Peru Carrera de Medicina HumanaUniversidad Científica del SurLima 15067Peru 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2024年第30卷第9期

页      面：1073-1095页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Diabetes mellitus Hypoglycemia Thyroid diseases Hypogonadism Metabolic bone diseases Liver cirrhosis 

摘      要：Hepatocrinology explores the intricate relationship between liver function and the endocrine *** liver diseases such as liver cirrhosis can cause endocrine disorders due to toxin accumulation and protein synthesis *** its importance,assessing endocrine issues in cirrhotic patients is frequently *** article provides a comprehensive review of the epidemiology,pathophysiology,diagnosis,and treatment of endocrine disturbances in liver *** review was conducted using the PubMed/Medline,EMBASE,and Scielo databases,encompassing 172 *** cirrhosis is associated with endocrine disturbances,including diabetes,hypoglycemia,sarcopenia,thyroid dysfunction,hypogonadotropic hypogonadism,bone disease,adrenal insufficiency,growth hormone dysfunction,and secondary *** optimal tools for diagnosing diabetes and detecting hypoglycemia are the oral glucose tolerance test and continuous glucose monitoring system,*** can be assessed through imaging and functional tests,while other endocrine disorders are evaluated using hormonal assays and imaging *** options include metformin,glucagon-like peptide-1 analogs,sodium-glucose co-transporter-2 inhibitors,and insulin,which are effective and safe for diabetes *** standards are followed for managing hypoglycemia,and hormone replacement therapy is often necessary for other endocrine *** transplantation can address some of these problems.