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Effect of copper, sulfur, arsenic and antimony on silver distribution in phases of lead blast furnace

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Transactions of Nonferrous metals Society of China 2014年第4期24卷 1202-1209页

作者： J.CHAIDEZ-FELIX A.ROmERO-SERRANO A.HERNANDEZ-RAmIREZ m.perez-labra I.ALmAGUER-GUZmAN R.BENAVIDES-perez m.FLORES-FAVELA metallurgy and materials Department IPN-ESIQIE UPALMZacatenco Academic Area of Earth Science and materials UAEH Col. CarbonerasMineral de la Reforma Servicios Administrativos Peoles S.A de C.V. Prol. Comonfort Sur 2050 Col. L. Echeverria

An experimental study was carried out to estimate the effect of the lead impurities on the silver distribution in the phases formed in the lead blast furnace. Samples of sinter with different contents of Cu, S, As and Sb were equilibrated under reducing atmosphere （p（CO）/p（CO2）=2.45） at 1573 K in a tube furnace and slowly cooled. The samples were characterized by scanning electron microscopy and microanalysis （SEm-EDS）. There were five immiscible phases：slag （CaO, FeO and SiO2）, matte （S, Cu and Fe）, speiss （As, Fe and Cu）, Cu-Sb phase and lead bullion （Pb, Ag, Sb, Cu, etc）. The results showed that Cu and Sb promote silver losses during the process since they form a liquid solution with higher silver solubility than liquid bullion. Sulfur and arsenic react with copper to form the matte and speiss phases, respectively. The effect of S and As is to reduce the amount of Cu-Sb alloy and then the silver losses from the bullion.

关键词： lead blast furnace silver lead impurities

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A comparative study of two methods for treatment of benign paroxysmal positional vertigo in the emergency department

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Journal of Otology 2021年第4期16卷 231-236页

作者： D.Giardino m.musazzi m.perez Akly m.Cherchi D.A.Yacovino Department of Neurology d Dr Cesar milstein Hospital Buenos AiresArgentina Department of Neurology d Centro de Educacion medica e Investigaciones Clínicas“Norberto Quirno”(CEmIC) Buenos AiresArgentina Department of Neurology d Feinberg School of medicine Northwestern UniversityChicagoILUSA Chicago Dizziness and Hearing ChicagoILUSA memory and Balance Clinic Buenos AiresArgentina

Introduction: Posterior canal benign paroxysmal positional vertigo (PC-BPPV) is considered the mostcommon cause of peripheral vertigo in the emergency department (ED). Although the canalith repositioning maneuver (CRm) is the standard of care, the most effective method to deliver it in the ED hasbeen poorly ***: To compare two protocols of the Epley maneuver for the treatment of *** and methods: We prospectively recruited 101 patients with unilateral PC-BPPV on physical examination, randomizing them to either a single Epley maneuver (Em) (n ¼ 46) or multiple maneuvers(n ¼ 55) on the same visit. measured outcomes included presence/absence of positional nystagmus,resolution of vertigo, and score on the dizziness handicap inventory (DHI) at follow-up evaluations. TheDHI was stratified into mild ( 30) and moderate-severe (>30).Results: Normalization of the Dix-Hallpike maneuver at day 5 was observed in 38% of the single Emgroup and 44.4% in the multiple Em group (p ¼ 0.62). The DHI showed reduction from 42.2 (SD 18.4) to31.9 (SD 23.7) in the single Em group and from 43.7 (SD 22.9) to 33.5 (SD 21.5) in the multiple Em group(p ¼ 0.06). A higher number of patients improved from moderate-severe to mild DHI (p ¼ 0.03) in thesingle Em group compared to the multi-Em group (p ¼ 0.23).Conclusion: There was no statistically significant difference between performing a single Em versusmultiple Ems for treatment of PC-BPPV in the emergency department. The single Em approach isassociated with shorter physical contact between patients and examiner, which is logically safer in apandemic context.

关键词： Benign paroxysmal positional vertigo Epley maneuver Emergency department Pandemic

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Regulatory effects of miR-19a on mAD2 expression and tumorigenesis in gastric cancer

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Genes & Diseases 2023年第4期10卷 1180-1182页

作者： J.Bargiela-Iparraguirre J.m.Herrero N.Pajuelo-Lozano m.perez R.Perona A.G.Quiroga C.Calés I.Sanchez-perez Dpto.de Bioquímica.Fac.medicina UAMMadrid 28029Spain Biomedical Research Institute of madrid CSIC/UAMMadrid 28029Spain Cancer Stem Cell and Fibroinflammatory microenvironment Group Chronic Diseases and Cancer Area 3-Instituto Ramón y Cajal de Investigación Sanitaria(IRYCIS)Madrid 28034Spain Unidad Asociada de Biomedicina UCLm-CSIC madrid 28029 Spain CIBER for Rare Diseases(CIBERER) Instituto de Salud CarlosⅢ Madrid 28029Spain Dpto.de Anatomía Histología y Neurociencia.Fac.Medicina UAMMadrid 28029Spain g Dpto.de Química Inorgánica Fac.Ciencias UAMMadrid 28049Spain

Gastric cancer(GC)is worldwide the sixth most diagnosed and third leading cause of cancer deaths,with poor and late prognosis,probably due to post-surgery adjuvant treatment resistance and lack of a thorough panel of prognostic *** have previously shown that mitotic arrest deficient 2(mAD2,encoded by mAD2L1),a key protein of the spindle assembly checkpoint,is relevant in GC cells;its interference impairs migration and growth,while its overexpression cor-relates with tumorigenesis.

关键词： mAD2 tumorigenesis Gastric

Evidence-based Rapid Review to Approach Diagnostic Test Research. A Veterinary Practitioners Opinion

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Veterinary Science Research 2021年第1期3卷 25-27页

作者： Julio A.Arenas Jeff m.perez Advanced Veterinary Centre Madinat Khalifa SouthDohaQatar

In animal research systematic reviews and meta-analysis have been playing an important role in improving the quality of evidence that professionals use ***,it is claimed that it is in its initial stage of *** veterinary medicine the heterogeneity in the evaluation of variables of exposure and response makes it difficult to gather the data results for a meta-analysis and evidence-based rapid reviews and other types of reviews can accelerate the way how we obtain this information and a problem-solving approach can be developed in the veterinary medicine field.

关键词： Evidence-based medicine Systematic review Rapid review meta-analysis

mechanical thrombectomy in patients with m1 occlusion and NIHSS score≤5:a single-centre experience

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Stroke & Vascular Neurology 2016年第4期1卷 165-171页

作者： P Bhogal P Bucke O Ganslandt H Bazner H Henkes m Aguilar perez Neuroradiological Clinic NeurocenterKlinikum StuttgartStuttgartGermany Neurological Clinic NeurocenterKlinikum StuttgartStuttgartGermany Neurosurgical Clinic NeurocenterKlinikum StuttgartStuttgartGermany medical Faculty University Duisburg-EssenStuttgartGermany

Background:The recent success of several mechanical thrombectomy trials has resulted in a significant change in management for patients presenting with ***,it is still unclear how to manage patients that present with stroke and low National Institutes of Health Stroke Scale(NIHSS)≤*** sought to review our experience of mechanical thrombectomy in patients with low NIHSS and confirmed m1 ***:We retrospectively analysed our prospectively maintained database of all patients undergoing mechanical thrombectomy between January 2008 and August *** identified 41 patients with confirmed m1 occlusion and low NIHSS(≤5)on admission to our *** collected demographic,radiological,procedural and outcome ***:The mean age of patients was 72±14,with 20 male *** medical conditions were common with hypertension seen in∼80%.Just over 50%presented with NIHSS 4 or *** average ASPECTS score on admission was 8.8(range 6–10),and the average clot length 10 *** Thrombolysis in Cerebral Infarction(TICI)≥2b was obtained in 87.8%of patients.7 patients had haemorrhage on follow-up,2 of which were *** 40 patients with 90-day follow-up,75%had modified Rankin Scale(mRS)score 0–*** were 3 deaths at 90 ***:mechanical thrombectomy in patients with low NIHSS and proximal large vessel occlusion is technically possible and carries a high degree of success with good safety *** with low NIHSS and confirmed occlusion should be considered for mechanical thrombectomy.

关键词： patients occlusion throm

The role of hypoxia-induced factor 1α in breast cancer

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Journal of Cancer metastasis and Treatment 2019年第6期4卷 44-54页

作者： Carlos Henrique F.Peiró Jéssica A.Encina matheus m.perez Glauco S.A.Aquino Glaucia L.Veiga Fernando Fonseca Beatriz C.A.Alves Laboratório de Análises Clínicas da Faculdade e medicina do ABC Santo AndréSP CEP 09060-650Brazil Instituto de Ciências Farmacêuticas Universidade Federal de São PauloDiademaSP CEP 09972-270Brazil

Breast cancer usually grows very quickly,becoming insensitive to blood flow in nearby veins;because of that,inside solid tumors it's possible to find a hypoxic environment,in other words,an environment where oxygen is less *** feature of cancer is its angiogenesis rate,because of the high energy demand,new blood vessels must be produced to take nutrients inside the solid tumor *** with normal blood flow bringing the cancer oxygen and nutrients,its cells favor hypoxia,in an event known as Warburg *** to the Warburg Effect,cells,even with normal oxygen rates,prefer to use fermentation instead of the citric acid cycle to produce *** the cancer to operate normally in hypoxia,a transcription factor family is activated,known as hypoxia-induced factors(HIF),composed of a HIF-1βand a HIF-1α*** HIF-1αis expressed during hypoxia,it is a great target for treatments and a breast cancer *** of the role of HIF-1αin cancer and the high incidence of breast cancer worlwide,this review was performed in order to bring the most recent results concerning the role HIF-1αcan exert in breast cancer development and progression.

关键词： Breast neoplasms hypoxia-induced factor 1 HIF-1α

Nonlinear forced vibration in a subcritical regime of a porous functionally graded pipe conveying fluid with a retaining clip

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 101-122页

作者： m.GHOLAmI m.EFTEKHARI Department of mechanical Engineering Shahid Bahonar University of Kerman

This study examines the nonlinear behaviors of a clamped-clamped porous pipe made of a functionally graded material(FGm) that conveys fluids and is equipped with a retaining clip, focusing on primary resonance and subcritical dynamics. The nonlinear governing equations for the FGm pipe are derived by the extended Hamilton's principle, and subsequently discretized through the application of the Galerkin *** direct method of multi-scales is then used to solve the derived equations. A thorough analysis of various parameters, including the clip stiffness, the power-law index, the porosity, and the clip location, is conducted to gain a comprehensive understanding of the system's nonlinear dynamics. Through the analysis of the first natural frequency, the study highlights the influence of the flow velocity and the clip stiffness, while the comparisons with metallic pipes emphasize the role of FGm composition. The examination of the forced response curves reveals saddle-node bifurcations and their dependence on parameters such as the detuning parameter and the power-law index, offering valuable insights into the system's nonlinear resonant behavior. Furthermore, the frequency-response curves illustrate the hardening nonlinearities influenced by factors such as the porosity and the clip stiffness, revealing nuanced effects on the system response and resonance characteristics. This comprehensive analysis enhances the understanding of nonlinear behaviors in FGm porous pipes with a retaining clip, providing key insights for practical engineering applications in system design and optimization.

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Photosynthetic Regulation of the Cyanobacterium Synechocystis sp. PCC 6803 Thioredoxin System and Functional Analysis of TrxB （Trx x） and TrxQ （Trx y） Thioredoxins

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molecular Plant 2009年第2期2卷 270-283页

作者： m. Esther perez-perez Eugenio martin-Figueroa Francisco J. Florencio Instituto de Bioquimica Vegetal y Fotosintesis Universidad de Sevilla-CSIC Avda Americo Vespucio 49 41092-Sevilla Spain

The expression of the genes encoding the ferredoxin-thioredoxin system including the ferredoxin-thioredoxin reductase （FTR） genes ftrC and ftrV and the four different thioredoxin genes trxA （m-type; sir0623）, trxB （x-type; sir1139）, trxC （sll1057） and trxQ （y-type; sir0233） of the cyanobacterium Synechocystis sp. PCC 6803 has been studied according to changes in the photosynthetic conditions. Experiments of light-dark transition indicate that the expression of all these genes except trxQ decreases in the dark in the absence of glucose in the growth medium. The use of two electron transport inhibitors, 3-（3,4-dichlorophenyl）-1,1-dimethylurea （DCmU） and 2,5-dibromo-3-methyl-6-isopropyl-p- benzoquinone （DBmIB）, reveals a differential effect on thioredoxin genes expression being trxC and trxQ almost unaffected, whereas trxA, trxB, and the ftr genes are down-regulated. In the presence of glucose, DCmU does not affect gene expression but DBmIB still does. Analysis of the single TrxB or TrxQ and the double TrxB TrxQ Synechocystis mutant strains reveal different functions for each of these thioredoxins under different growth conditions. Finally, a Synechocystis strain was generated containing a mutated version of TrxB （TrxBC34S）, which was used to identify the potential in-vivo targets of this thioredoxin by a proteomic analysis.

关键词： Cyanobacteria photosynthetic electron transport Synechocystis oxidative stress thioredoxin.

Occurrence data may provide unreliable thermal preferences and breadth of species

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Current Zoology 2015年第6期61卷 972-982页

作者： Sara VILLEN-perez Luis m. CARRASCAL Department of Biogeography and Global Change National Museum of Natural Sciences MNCN-CSIC. C/José Gutiérrez Abascal 2 28006 Madrid Spain.

Accurate information on the thermal preference and specialization of species is needed to understand and predict spe- cies geographical range size and vulnerability to climate change. Here we estimate the position and breadth of species within thermal gradients based on the shape of the response curve of species abundance to temperature. The objective of the study is to compare the measurements of this approach based on abundance data with those of the classical approach using species＇ occur- rence data. The relationship between species＇ relative abundance and minimum winter temperature of 106 bird species wintering in the Iberian Peninsula is modeled at 100 Km2 resolution with quadratic logistic regressions. From these models we calculated the preferred temperature of species as the temperature at which the abundance is maximized, and the thermal breadth of species as the relative area under the temperature-abundance curve. We also estimated the thermal preferences and breadth of species as the average temperature and temperature range of the UTm cells in which the species are present. The abundance-temperature response curves reveal that birds prefer higher temperatures to overwinter, and are more thermally selective, than is measured by the classical approach. moreover, response curves detect a higher inter-specific variability in both thermal preferences and ther- mal breadth of species. As occurrence data gives the same weight to cells with one or many individuals, the average temperature of the cells in which the species is present roughly reflects the average temperature in the region of study and not the environ- mental preferences of species .

关键词： Abundance-temperature response curve Birds Species occurrence Thermal breadth Thermal preferences Winter