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Total phenolic content,in vitro antioxidant activity and chemical composition of plant extracts from semiarid Mexican region

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Asian Pacific Journal of Tropical Medicine 2015年第2期8卷 104-111页

作者： Jorge E.Wong-Paz Juan C.Contreras-Esquivel Raúl rodríguez-Herrera maría L.Carrillo-Inungaray Lluvia I.López Guadalupe V.Nevárez-Moorillón Cristóbal N.Aguilar Laboratory of Bioprocesses and Natural Products Food Research DepartmentSchool of ChemistryUniversidad Autónoma de CoahuilaSaltillo25280México Laboratory of Biochemistry Multidisciplinary Academic Unit-HuastecaUniversidad Autónoma de San Luis Potosí79060Cd.VallesS.L.P.Mexico Department of Microbiology School of ChemistryUniversidad Autónoma de Chihuahua31125 ChihuahuaMexico

Objective:To determine the extraction suitable conditions of total phenolic content(TPC) by heat-reflux system,antioxidant activities and HPLC characterization of the aqueous-ethanolic extracts of Jatropha dioica(***)(Dragon's blood).Flourensia cernua(***)(Tar bush).Eucalyptus camaldulensis(***)(Eucalyptus) and Turnera diffusa(***)(Damiana).Methods:TPC was evaluated by the well-known colorimetric assay using FolinCiocalteu *** antioxidant activities were assayed by three methods based on scavenging of DPPH,ABTS and by lipid oxidation *** chemical composition of the extracts obtained was subject to HPLC ***:TPC in the plant extracts ranged from 2.3 to14.12 mg gallic acid equivalents/g for *** and ***,*** plant extracts of ***,*** and *** showed similar strong antioxidant activities on scavenging of DPPH and lipid oxidation *** contrast,*** extracts had lowest potential antioxidant in three assays *** assay showed the presence of several phenolic compounds in the extracts ***:The results obtained suggest that ***,*** and *** are potential sources to obtain bioactive phenolic compounds with high antioxidant properties which can be used in the factories as antioxidant agents or for treatments in diseases.

关键词： Plant-extracts Polyphenols Natural antioxidants Mexican plants Heat-reflux system

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Camera traps reveal the natural corridors used by mammalian species in eastern Mexico

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Ecological Processes 2022年第1期11卷 711-722页

作者： Jonathan O.Huerta‑rodríguez Octavio C.Rosas‑Rosas Lauro López‑Mata JoséL.Alcántara‑Carbajal luis A.Tarango‑Arámbula Programa de Recursos Genéticos y Productividad‑Ganadería Colegio de Post‑graduadosCampus MontecilloTexcocoMexico Programa de Innovación en Manejo de Recursos Naturales Colegio de PostgraduadosCampus San Luis PotosíSan Luis PotosíMexico Programa de Dinámica y Conservación de Bosques y Selvas Macroecología y BiodiversidadColegio de PostgraduadosCampus MontecilloTexcocoMexico

Background:Habitat loss and fragmentation in the Sierra Madre Oriental(SMO)ecological corridor have negative impacts on the movement and distribution of mammalian species that are of great ecological and evolutionary *** of the SMO ecological corridor that is located in the state of Hidalgo is less studied despite being a potential dispersal route for *** objectives of this study were to evaluate the presence and activity of terrestrial mammals in the riparian and non‑riparian zones of ***:Camera traps detected 15 mammalian species(i.e.,14 native and 1 domestic)in the non‑riparian zone,and 12 mammalian species in the riparian zone(i.e.,10 wild and 2 domestic).The riparian corridor was mainly used by opportunistic medium‑sized carnivores,while large carnivores and their potential prey were more frequent in the non‑riparian ***:Our findings suggest terrestrial mammals avoid the use of natural corridors due to the presence of domestic dogs,cattle and humans and look for new dispersal routes to move through their habitat and find the resources they need to *** though some species can use disturbed corridors to move and find resources,they will change their activity patterns to avoid contact with humans and potential threats like *** is,therefore,crucial to identify not one,but several corridors that must be preserved to improve the connectivity of terrestrial mammals in disturbed landscapes.

关键词： Activity Jaguar Cattle Detectability Dog Herbivore Disturbance Prey Relative abundance

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Concordance among pulse wave velocity assessment methods: A network meta-analysis

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中华医学杂志(英文版) 2024年第17期137卷 2137-2139页

作者： Cavero-Redondo Iván Sequí-Domínguez Irene Saz-Lara Alicia Garcia-Klepzig Jose luis Lucerón-Lucas-Torres maribel martínez-García Irene álvarez-Bueno Celia martínez-Vizcaíno Vicente CarVasCare Research Group Facultad de Enfermería de Cuenca Universidad de Castilla-La Mancha Cuenca Spain Facultad de Ciencias de la Salud Universidad Autónoma de Chile Talca Chile Health and Social Research Center Universidad de Castilla-La Mancha Cuenca Spain Internal Medicine Department San Carlos University Hospital Madrid Spain Universidad Politécnica y Artística del Paraguay Asunción Paraguay

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Muscle strength deficits are associated with low bone mineral density in young pediatric cancer survivors:The iBoneFIT project

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Journal of Sport and Health Science 2024年第3期13卷 419-427页

作者： Andres marmol-Perez Jose J.Gil-Cosano Esther Ubago-Guisado Francisco J.Llorente-Cantarero Juan Francisco Pascual-Gázquez Kirsten K.Ness Vicente martinez-Vizcaino Jonatan R.Ruiz luis Gracia-marco Department of Physical Education and Sports Faculty of Sport SciencesSport and Health University Research Institute(iMUDS)University of GranadaGranada 18011Spain Department of Epidemiology and Cancer Control St.Jude Children's Research HospitalMemphisTN 38105USA Department of Communication and Education Loyola University AndalusiaSeville 41704Spain Biosanitary Research Institute ibs.GranadaGranada 18012Spain Maimonides Biomedical Research Institute of Cordoba(IMIBIC) Cordoba 14004Spain CIBEROBN Biomedical Research Networking Center for Physiopathology of Obesity and NutritionCarlos III Health InstituteMadrid 28029Spain Department of Specific Didactics Faculty of EducationUniversity of CordobaCordoba 14071Spain Pediatric and adolescent hematology and oncology service Pediatrics and Pediatric Surgery Clinical Management UnitVirgen de las Nieves University HospitalGranada 18014Spain Health and Social Research Center Universidad de Castilla-La ManchaCuenca 13001Spain

Background Pediatric cancer survivors are at increased risk of muscle weakness and low areal bone mineral density(aBMD).However,the prevalence of muscle strength deficits is not well documented,and the associations of muscle strength with aBMD are unknown in this ***,this study aimed to investigate the prevalence of upper-and lower-body muscle strength deficits and to examine the associations of upper-and lower-body muscle strength with age-,sex,and race-specific aBMD Z-scores at the total body,total hip,femoral neck,and lumbar *** This cross-sectional study included 116 pediatric cancer survivors(12.1±3.3 years old,mean±SD;42.2%female).Upper-and lower-body muscle strength were assessed by handgrip and standing long jump test,***‑energy X‑ray absorptiometry was used to measure aBMD(g/cm2).Associations between muscle strength and aBMD were evaluated in multivariable linear regression *** regression was used to evaluate the contribution of muscle strength(1-decile lower)to the odds of having low aBMD(Z-score≤1.0).All analyses were adjusted for time from treatment completion,radiotherapy exposure,and body mass *** More than one-half of survivors were within the 2 lowest deciles for upper-(56.9%)and lower-body muscle strength(60.0%)in comparison to age-and sex-specific reference *** strength deficits were associated with lower aBMD Z-scores at all sites(B=0.133–0.258,p=0.001–0.032).Each 1-decile lower in upper-body muscle strength was associated with 30%–95%higher odds of having low aBMD Z-scores at all *** 1-decile lower in lower-body muscle strength was associated with 35%–70%higher odds of having low aBMD Z-scores at total body,total hip,and femoral *** Muscle strength deficits are prevalent in young pediatric cancer survivors,and such deficits are associated with lower aBMD Z-scores at all *** results suggest that interventions designed to improve muscle strength in t

关键词： Bone health Childhood cancer DXA Lean mass Resistance training

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Diagnostic-therapeutic management of bile duct cancer

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World Journal of Clinical Cases 2019年第14期7卷 1732-1752页

作者： José maría Huguet Miriam Lobo José Mir Labrador Carlos Boix Cecilia Albert luis Ferrer-Barceló Ana B Durá Patricia suárez Isabel Iranzo Mireia Gil-Raga Celia Baez de Burgos Javier Sempere Digestive Disease Department General University Hospital of ValenciaValencia 46014Spain Medical Oncology Department General University Hospital of ValenciaValencia 46014Spain Unidad Hepática Avanzada Servicio de Cirugía General y DigestivaGeneral University Hospital of ValenciaValencia 46014Spain Medical Oncology Department Hospital de RequenaRequena 46340Spain

Biliary tract cancer, or cholangiocarcinoma, comprises a heterogeneous group of malignant tumors that can emerge at any part of the biliary tree. This group is the second most common type of primary liver cancer. Diagnosis is usually based on symptoms, which may be heterogeneous, and nonspecific biomarkers in serum and biopsy specimens, as well as on imaging techniques. Endoscopy-based diagnosis is essential, since it enables biopsy specimens to be taken. In addition, it can help with locoregional staging of distal tumors. Endoscopic retrograde cholangiopancreatography is a key technique for the evaluation and treatment of malignant biliary tumors. Correct staging of cholangiocarcinoma is essential in order to be able to determine the degree of resectability and assess the results of treatment. The tumor is staged based on the TNM classification of the American Joint Committee on Cancer. The approach will depend on the classification of the tumor. Thus, some patients with early-stage disease could benefit from surgery;complete surgical resection is the cornerstone of cure. However, only a minority of patients are diagnosed in the early stages and are suitable candidates for resection. In the subset of patients diagnosed with locally advanced or metastatic disease, chemotherapy has been used to improve outcome and to delay tumor progression. The approach to biliary tract tumors should be multidisciplinary, involving experienced endoscopists, oncologists, radiologists, and surgeons.

关键词： Bile duct cancer Cholangiocarcinoma Management Diagnosis Incidence Multidisciplinary treatment

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Quantification of the Vertical Load Applied to the Pavement during Cornering Maneuver of a Battery Electric Commercial Vehicle

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Journal of Traffic and Transportation Engineering 2024年第5期12卷 207-213页

作者： Pablo Kubo Ney Siqueira Gilberto Grossl luis Welin Mairon Dobicz marcio Andrade Department of Complete Vehicle Volvo Group North AmericaGreensboro 27409USA Department of Complete Vehicle Volvo Trucks BrazilCuritiba 81260-900Brazil

The wheel loads of heavy trucks are the major source of pavement damage,given the repeated loadings imposed by them due to transient events and surface *** related studies focus on steady-state context regarding simplified vehicle’s parameters and ideal pavement conditions,this paper aims to analyze the vertical load applied to the pavement by considering cornering maneuver as a transient event,on a battery electric vehicle *** this concern,measurements were performed on a rigid truck,with two steering front axles,in a closed course proving *** relationship has been presented between vehicle’s speed,lateral acceleration and transferred vertical load for a given curve radius of 85.6 m and 3.7°of transversal *** measurements results indicated that for every 10 km/h increasing on the vehicle’s speed,additional 110 kgf will be transferred to the pavement on the outer side of the cornering *** value itself could not be considered high,but it will be also added to the static load,or overload in some truck applications.

关键词： Load transfer durability vehicle dynamics

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An optimized high quality male DNA extraction from spermatophores in open thelycum shrimp species

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Integrative Zoology 2017年第5期12卷 421-427页

作者： Laia PLANELLA Sandra HERAS Manuel VERA José-luis GARCÍA-marÍN maría Inés ROLDÁN Laboratory of Genetic Ichthyology University of GironaGironaSpain

The crucial step of most of the current genetic studies is the extraction of DNA of sufficient quantity and *** genomic DNA isolation methods have been described to successfully obtain male DNA from shrimp ***,all current protocols require invasive handling methods with males for DNA *** Aristeus antennatus as a model we tested a reliable non-invasive differential DNA extraction method to male DNA isolation from spermatophores attached to female *** present protocol provides high quality and quantity DNA for polymerase chain reaction amplification and male *** new approach could be useful to experimental shrimp culture to select sires with relevant genetic patterns for selective breeding *** importantly,it can be applied to identify the mating pairs and male structure in wild populations of species as ***,where males are often difficult to *** method could be also valuable for biological studies on other spermatophore-using species,such as myriapods,arachnids and insects.

关键词： differential spermatophore DNA extraction high quality DNA male genotyping non-invasive DNA extraction open thelycum shrimp

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Role of microRNAs in alcohol-induced liver disorders and non-alcoholic fatty liver disease

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World Journal of Gastroenterology 2018年第36期24卷 4104-4118页

作者： Jorge-luis Torres Ignacio Novo-Veleiro Laura Manzanedo Lucía Alvela-suárez Ronald Macías Francisco-Javier Laso Miguel marcos Department of Internal Medicine University Hospital of SalamancaInstitute of Biomedical Research of Salamanca-IBSAL Spanish Working Group on Alcohol and Alcoholism Spanish Society of Internal Medicine Department of Internal Medicine University Hospital of Santiago de Compostela Department of Internal Medicine HM Rosaleda HospitalSantiago de Compostela Department of Medicine Faculty of MedicineUniversity of Salamanca

MicroRNAs(miRNAs) are small non-coding RNAs that regulate multiple physiological and pathological functions through the modulation of gene expression at the post-transcriptional level. Accumulating evidence has established a role for miRNAs in the development and pathogenesis of liver disease. Specifically, a large number of studies have assessed the role of miRNAsin alcoholic liver disease(ALD) and non-alcoholic fatty liver disease(NAFLD), two diseases that share common underlying mechanisms and pathological characteristics. The purpose of the current review is to summarize and update the body of literature investigating the role of miRNAs in liver disease. In addition, the potential use of miRNAs as biomarkers and/or therapeutic targets is discussed. Among all miRNAs analyzed, miR-34 a, miR-122 and miR-155 are most involved in the pathogenesis of NAFLD. Of note, these three miRNAs have also been implicated in ALD, reinforcing a common disease mechanism between these two entities and the pleiotropic effects of specific miRNAs. Currently, no single miRNA or panel of miRNAs has been identified for the detection of, or staging of ALD or NAFLD. While promising results have been shown in murine models, no therapeutic based-miRNA agents have been developed for use in humans with liver disease.

关键词： Alcohol use disorder Alcoholic liver disease Non-alcoholic fatty liver disease Steatosis Obesity miRNA Biomarkers

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Watch out for Abdominal Pain in HIV-AIDS Patients: Abdominal Tuberculosis

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Case Reports in Clinical Medicine 2020年第12期9卷 392-398页

作者： maría rodríguez-Santiago luis Alvarez-Pérez José Gaudier-Díaz Pedro Gil-De Rubio Natalia Hernández-Cuevas José Colón-Márquez Department of Internal Medicine University of Puerto Rico School of Medicine San Juan Puerto Rico

Extrapulmonary Tuberculosis (EPTB) is the TB involving organs other than lungs. The diagnosis of EPTB can be difficult, as suspicion is challenging, because it presents with nonspecific clinical features and atypical presentation. Furthermore, patients with HIV may present with fever of unknown origin (FUO) as the only symptom. We present a clinical case of a 49 years old Puertorrican female with HIV-AIDS and no high-risk behavior with an abdominal pain and fever. The investigation confirmed an Abdominal Tuberculosis. This case emphasizes the need to add Abdominal tuberculosis (ATB) within the differential diagnosis and discuss the diagnostic process.

关键词： Abdominal Pain Abdominal Tuberculosis (ATB) Diagnosing ATB HIV/AIDS

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Colorectal cancer screening and surveillance in patients with inflammatory bowel disease in 2021

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World Journal of Gastroenterology 2022年第5期28卷 502-516页

作者： Jose maria Huguet luis Ferrer-Barceló Patrícia suárez Eva Sanchez Jose David Prieto Victor Garcia Javier Sempere Department of Digestive Disease General University Hospital of ValenciaValencia 46014Spain

The detection of dysplasia in patients with inflammatory bowel disease(IBD)continues to be important given the increased risk of colorectal cancer in this ***,in 2017,we performed a review and update of the recommendations for the management and follow-up of patients with IBD based on the clinical practice guidelines of various scientific *** present manuscript focuses on new aspects of the detection,follow-up,and management of dysplasia according to the latest studies and *** chromoendoscopy with targeted biopsy continues to be the technique of choice for the screening and detection of dysplasia in IBD,the associated difficulties mean that it is now being compared with other techniques(virtual chromoendoscopy),which yield similar results with less technical ***,the emergence of new endoscopy techniques that are still being researched but seem promising(e.g.,confocal laser endomicroscopy and full-spectrum endoscopy),together with the development of devices that improve endoscopic visualization(e.g.,Endocuff Vision),lead us to believe that these approaches can revolutionize the screening and follow-up of dysplasia in patients with ***,further studies are warranted to define the optimal follow-up strategy in this patient population.

关键词： Colitis surveillance Colitis screening Chromoendoscopy Colorectal cancer Inflammatory bowel disease Ulcerative colitis

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