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Micro segment analysis of supercritical methane thermal-hydraulic performance and pseudo-boiling in a PCHE straight channel

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Petroleum Science 2024年第2期21卷 1275-1289页

作者： qian Li zi-Jie Lin liu Yang Yue Wang Yue Li Wei-Hua Cai Laboratory of Thermo-Fluid Science and Nuclear Engineering Northeast Electric Power UniversityJilin132000JilinChina School of Energy and Power Engineering Northeast Electric Power UniversityJilin132000JilinChina

The printed circuit heat exchanger(PCHE) is receiving wide attention as a new kind of compact heat exchanger and is considered as a promising vaporizer in the LNG process. In this paper, a PCHE straight channel in the length of 500 mm is established, with a semicircular cross section in a diameter of 1.2 *** simulation is employed to investigate the flow and heat transfer performance of supercritical methane in the channel. The pseudo-boiling theory is adopted and the liquid-like, two-phase-like, and vapor-like regimes are divided for supercritical methane to analyze the heat transfer and flow *** results are presented in micro segment to show the local convective heat transfer coefficient and pressure drop. It shows that the convective heat transfer coefficient in segments along the channel has a significant peak feature near the pseudo-critical point and a heat transfer deterioration when the average fluid temperature in the segment is higher than the pseudo-critical point. The reason is explained with the generation of vapor-like film near the channel wall that the peak feature related to a nucleateboiling-like state and heat transfer deterioration related to a film-boiling-like state. The effects of parameters, including mass flow rate, pressure, and wall heat flux on flow and heat transfer were *** calculating of the averaged heat transfer coefficient of the whole channel, the traditional method shows significant deviation and the micro segment weighted average method is adopted. The pressure drop can mainly be affected by the mass flux and pressure and little affected by the wall heat flux. The peak of the convective heat transfer coefficient can only form at high mass flux, low wall heat flux, and near critical pressure, in which condition the nucleate-boiling-like state is easier to appear. Moreover,heat transfer deterioration will always appear, since the supercritical flow will finally develop into a filmboiling-like state. So hea

关键词： Printed circuit heat exchanger Vaporization Supercritical methane Pseudo-boiling Micro segment analysis

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Current trends and hotspots of depressive disorders with colorectal cancer:A bibliometric and visual study

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3687-3704页

作者： zi-Wei Yan Ying-Nan liu qian Xu Yuan Yuan Tumor Etiology and Screening Department of Cancer Institute and General Surgery The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Key Laboratory of Cancer Etiology and Prevention in Liaoning Education Department The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Laboratory of GI Cancer Etiology and Prevention in Liaoning Province The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina

BACKGROUND Depression is strongly associated with colorectal cancer(CRC).Few bibliometric analyses have systematically summarized the research focus and recent progress in this *** To determine the research status and hotspots by bibliometric analysis of relevant publications on the relationship between CRC and *** Articles on depression in CRC patients were collected from the Web of Science Core *** and VOSviewer software were used to visualize bibliometric *** From 2001 to 2022,Supportive Care in Cancer,the United States,Tilburg University,and Mols were the most productive and influential journal,country,institution,and author ***-occurrence cluster analysis of keywords placed quality of life,anxiety,and psychological stress in the center of the visual network *** clustering was performed for the clusters with studies of the relevant mechanism of action,which showed that:(1)Cytokines have a role essential for the occurrence and development of depressive disorders in CRC;(2)MicroRNAs have a role essential for the development of depressive disorders in CRC;(3)Some anticancer drugs have pro-depressant activity;and(4)Selective serotonin reuptake inhibitors have both antitumor and antidepressant *** Life quality and psychological nursing of the cancer population were key *** roles of cytokines and microRNAs,the pro-depression activity of anticancer drugs and their antitumor properties deserve in-depth study.

关键词： Depression Colorectal cancer Bibliometric analysis Cytokines Drugs Mechanism

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Hydrogen-Bonding Crosslinked Supramolecular Polymer Materials:From Design Evolution of Side-Chain Hydrogen-Bonding to Applications

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Chinese Journal of Polymer Science 2024年第11期 1619-1641页

作者： qian Zhang zi-Yang Xu Wen-Guang liu School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional MaterialsTianjin University

Hydrogen bonds (H-bonds) are the most essential non-covalent interactions in nature,playing a crucial role in stabilizing the secondary structures of *** inspiration from nature,researchers have developed several multiple H-bonds crosslinked supramolecular polymer materials through the incorporation of H-bond side-chain units into the polymer chains.N-acryloyl glycinamide (NAGA) is a monomer with dual amides in the side group,which facilitates the formation of multiple dense intermolecular H-bonds within poly(N-acryloyl glycinamide)(PNAGA),thereby exhibiting diverse properties dependent on concentration and meeting various requirements across different ***,numerous attempts have been undertaken to synthesize diverse NAGA-derived units through meticulous chemical structure regulation and fabricate corresponding H-bonding crosslinked supramolecular polymer *** this,the systematic clarification of the impact of chemical structures of side moieties on intermolecular associations and material performances remains *** present review will focus on the design principle for synthesizing NAGA-derived H-bond side-chain units and provide an overview of the recent advancements in multiple H-bonds crosslinked PNAGA-derived supramolecular polymer materials,which can be categorized into three groups based on the chemical structure of H-bonds units:(1) monomers with solely cooperative H-bonds;(2) monomers with synergistic H-bonds and other physical interactions;and (3) diol chain extenders with cooperative *** significance of subtle structural variations in these NAGA-derived units,enabling the fabrication of hydrogen-bonded supramolecular polymer materials with significantly diverse performances,will be ***,the extensive applications of multiple H-bonds crosslinked supramolecular polymer materials will be elucidated.

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Mechanical performance of 22SiMn2TiB steel welded with lowtransformation- temperature filler wire and stainless steel filler wire

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Journal of Iron and Steel Research International 2024年第4期31卷 967-981页

作者： zi-dong Lin Kai-jie Song Zhen Sun zi-qian Zhu Xue-feng Zhao Constantinos Goulas Wei Ya Xing-hua Yu School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401120China Department of Design Production and Management Faculty of Engineering Technology.University of TwenteEnschede 7500 AETheNetherlands Rotterdam Additive Manufacture Fieldlab(RAMLAB) Rotterdam 3089 JWTheNetherlands

TX-80 low-transformation-temperature(LTT)welding wire was used to replace the traditional ER 307Si welding wire to realize the connection of 22SiMn2TiB armor steel in manual overlay *** previously existing issues,such as welding cracks,large welding deformation,and severe welding residual stress,were solved to ensure good strength and ductility *** particular,with the same welding conditions,TX-80 LTT wire eliminates welding *** reduces the welding deformation no matter the base pretreatment of pre-setting angle or no pre-setting *** comparison,it was found that the microstructure at the TX-80 weld is mainly composed of martensite and a small amount of retained *** contrast,the microstructure of the ER 307Si weld consists of a large amount of austenite and a small amount of skeleton-like *** variation trend of residual stress and microhardness from the weld to the base were investigated and compared with the mechanical properties of base *** TX-80 and the ER 307Si tensile samples elongation is 6.76%and 6.01%,while the ultimate tensile strengths are 877 and 667 MPa,*** average impact toughness at room temperature of the ER 307Si weld is 143.9 J/cm^(2),much higher than that of the TX-80 weld,which is only 36.7 J/cm^(2).The relationship between impact and tensile properties with microstructure species and distribution was *** addition,the fracture surface of the tensile and the impact samples was observed and *** dimples,fewer pores,larger radiation zone,and shear lips of TX-80 samples indicate better tensile ductility and worse impact toughness than those of ER 307Si weld.

关键词： Low-transformation-temperature material 22SiMn2TiB steel Welding deformation Residual stress Martensitic transformation Mechanical property

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Ferritinophagy: A new idea for liver diseases regulated by ferroptosis

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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 160-170页

作者： zi-Bing qian Jun-Feng Li Wan-Yuan Xiong Xiao-Rong Mao The First Clinical Medical College of Lanzhou University Lanzhou 730000China Institute of Infectious Diseases The First Hospital of Lanzhou UniversityLanzhou 730000China Department of Infectious Disease The First Hospital of Lanzhou UniversityLanzhou 730000China

Background:The discovery of regulatory cell death has led to a breakthrough in the therapeutic *** forms of cell death,such as necrosis,apoptosis,pyroptosis,autophagy,and ferroptosis,play an important role in the development of liver *** general,more than one form of cell death pathways is responsible for the disease ***,it is particularly important to study the regulation and interaction of various cell death forms in liver *** sources:We performed a PubMed search up to November 2022 with the following keywords:ferritinophagy,ferroptosis,and liver *** also used terms such as signal path,inducer,and inhibitor to supplement the query ***:This review summarized the basic characteristics of ferritinophagy and ferroptosis and the regulation of ferroptosis by ferritinophagy and reviewed the key targets and treatment strategies of ferroptosis in different liver ***:Ferritinophagy is a potential therapeutic target in ferroptosis-related liver diseases.

关键词： Ferritinophagy Ferroptosis Liver disease

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Arbuscular mycorrhiza and plant growth promoting endophytes facilitates accumulation of saponin under moderate drought stress

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Chinese Herbal Medicines 2024年第2期16卷 214-226页

作者： Shubiao qian Qing Zhang Sha Li Rui Shi Xiahong He Shuhui zi Tao liu Yunnan Agricultural University Kunming 650201China National&Local Joint Engineering Research Center on Gemplasm Utilization&Innovation of Chinese Medicinal Materials in Southwest China Yunnan Agricultural UniversityKunming 650201China Institute of Sericulture and Honeybee Honghe 661101China Southwest Forestry University Kunming 650201China

Objective: Paris polyphylla var. yunnanensis, one of the important medicinal plant resources in Yunnan,China, usually takes 6–8 years to be harvested. Therefore, it is urgent to find a method that can not only shorten its growth years, but also improve its quality. In this study, we examined the effects of a combination treatment of arbuscular mycorrhizal fungi(AMF) and plant growth-promoting endophytes(PGPE)and drought stress on the accumulation of saponins in ***: P. polyphylla var. yunnanensis was infected with a mixture of AMF and PGPE under drought stress. The content of saponins, as well as morphological, physiological, and biochemical indicators, were all measured. The UGTs gene related to saponin synthesis was obtained from transcriptome data by homologous comparison, which were used for RT-PCR and phylogenetic ***: Regardless of water, AMF treatment could infect the roots of P. polyphylla var. yunnanensis, however double inoculation with AMF and PGPE(AMF + PGPE) would reduce the infection rate of AMF. Plant height, aboveground and underground fresh weight did not differ significantly between the single inoculation AMF and the double inoculation treatment under different water conditions, but the inoculation treatment significantly increased the plant height of P. polyphylla var. yunnanensis compared to the noninoculation treatment. Single inoculation with AMF considerably increased the net photosynthetic rate,stomatal conductance, and transpiration rate of P. polyphylla var. yunnanensis leaves under various water conditions, but double inoculation with AMF + PGPE greatly increased the intercellular CO2concentration and chlorophyll fluorescence parameter(Fv/Fm). Under diverse water treatments, single inoculation AMF had the highest proline content, whereas double inoculation AMF + PGPE may greatly improve the amount of abscisic acid(ABA) and indoleacetic acid(IAA) compared to normal water under moderate drought. Double inoculation AMF + P

关键词： arbuscular mycorrhizal fungi gene expression Paris polyphylla Smith var.yunnanensis (Franch.)Hand.-Mazz plant growth-promoting endophytes steroidal saponin

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子午工程二期流星雷达样机测试及数据对比分析

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地球与行星物理论评（中英文） 2024年第1期55卷 120-130页

作者：陈志青刘子谦冯健胡连欢燕春晓袁韦吴学森郑兵周小俊中国科学院国家空间科学中心北京100190 空间天气学国家重点实验室北京100190 中国电子科技集团公司第二十二研究所青岛266107 中国科学院地质与地球物理研究所北京100029 海南空间天气国家野外科学观测研究站儋州571700

子午工程二期将在分布于全国的10个观测站点建设流星雷达.为了带动国内空间环境地基观测技术的发展,工程建设项目指挥部布局了流星雷达的国产化专项行动.为了确保建成后的设备满足使用要求,工程总体组织了设备样机测试,包括设备的技术... 详细信息

子午工程二期将在分布于全国的10个观测站点建设流星雷达.为了带动国内空间环境地基观测技术的发展,工程建设项目指挥部布局了流星雷达的国产化专项行动.为了确保建成后的设备满足使用要求,工程总体组织了设备样机测试,包括设备的技术指标测试和数据质量评估.技术指标测试表明其满足要求.在获得数据之后,以EMDR流星雷达数据为参考,对样机的数据进行质量评估.主要对比参数包括有效流星计数、流星数时空分布、扩散系数高度分布、风场随高度的分布和随时间的变化等.本文主要展示了数据质量评估的结果,揭示了流星雷达观测的一些基本特征和规律,为数据准确性的评估提供参考和借鉴.

关键词：子午工程流星雷达样机测试数据质量

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基于流量矩阵估计的路由推断算法

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铁道学报 2005年第6期27卷 66-70页

作者：刘紫千陈常嘉北京交通大学电子信息工程学院北京100044

路由信息对网络而言非常重要。现有的路由推断技术很难适用于任意网络。本文提出了一种路由推断算法,在已知网络的拓扑结构和链路流量的情况下,先通过期望最大化算法对一个包含了多种路由可能性的流量矩阵进行估计,然后根据对应的可能... 详细信息

路由信息对网络而言非常重要。现有的路由推断技术很难适用于任意网络。本文提出了一种路由推断算法,在已知网络的拓扑结构和链路流量的情况下,先通过期望最大化算法对一个包含了多种路由可能性的流量矩阵进行估计,然后根据对应的可能需求的估计值的差异来推断实际路由。仿真结果证明了方法的有效性。

关键词：路由推断流量矩阵估计期望最大化算法

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五声性调式与音腔化语言在中国古典舞课堂音乐创作中的运用分析——以《中国古典舞身韵巡礼钢琴伴奏曲集》为例

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北京舞蹈学院学报 2021年第2期147卷 127-134页

作者：刘紫千中央民族大学舞蹈学院北京100081

中国传统音乐语汇中五声性调式及音腔化的发音特质决定了中国音乐的美感及韵味,好的中国古典舞音乐必须具备鲜明的民族调式特征和准确的音腔韵味。钢琴作为目前中国古典舞和身韵的课堂教学中最为普遍的西方伴奏乐器,如何发好"中国之声"... 详细信息

中国传统音乐语汇中五声性调式及音腔化的发音特质决定了中国音乐的美感及韵味,好的中国古典舞音乐必须具备鲜明的民族调式特征和准确的音腔韵味。钢琴作为目前中国古典舞和身韵的课堂教学中最为普遍的西方伴奏乐器,如何发好"中国之声",是本文要讨论的重点。以下通过对《中国古典舞身韵巡礼钢琴伴奏曲集》一书的实例分析,探讨在舞蹈钢琴伴奏学科中,中国古典舞课堂音乐创作的音乐语汇运用的一般规律,以期对中国古典舞课堂音乐创作提供经验。

关键词：中国古典舞音乐创作五声性调式音腔课堂教学应用

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The phenylalanine ammonia-lyase gene family in Isatis indigotica Fort.:molecular cloning,characterization,and expression analysis

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Chinese Journal of Natural Medicines 2016年第11期14卷 801-812页

作者： MA Rui-Fang liu qian-zi XIAO Ying ZHANG Lei LI Qing YIN Jun CHEN Wan-Sheng Development and Utilization Key Laboratory of Northeast Plant Materials School of Traditional Chinese Materia MedicaShenyang Pharmaceutical University College of Pharmacy Jiamusi University Department of Pharmacy Changzheng Hospital Second Military Medical University Department of Pharmaceutical Botany School of Pharmacy Second Military Medical University

Phenolic compounds, metabolites of the phenylpropanoid pathway, play an important role in the growth and environmental adaptation of many plants. Phenylalanine ammonia-lyase(PAL) is the first key enzyme of the phenylpropanoid pathway. The present study was designed to investigate whether there is a multi-gene family in I. Indigotic and, if so, to characterize their properties. We conducted a comprehensive survey on the transcription profiling database by using tBLASTn analysis. Several bioinformatics methods were employed to perform the prediction of composition and physicochemical characters. The expression levels of IiPAL genes in various tissues of I. indigotica with stress treatment were examined by quantitative real-time PCR. Protoplast transient transformation was used to observe the locations of IiPALs. IiPALs were functionally characterized by expression with pET-32a vector in Escherichia colis strain BL21(DE3). Integration of transcripts and metabolite accumulations was used to reveal the relation between IiPALs and target compounds. An new gene(IiPAL2) was identified and both IiPALs had the conserved enzymatic active site Ala-Ser-Gly and were classified as members of dicotyledon. IiPAL1 and IiPAL2 were expressed in roots, stems, leaves, and flowers, with the highest expression levels of IiPAL1 and IiPAL2 being observed in stems and roots, respectively. The two genes responded to the exogenous elicitor in different manners. Subcellular localization experiment showed that both IiPALs were localized in the cytosol. The recombinant proteins were shown to catalyze the conversion of L-Phe to trans-cinnamic acid. Correlation analysis indicated that Ii PAL1 was more close to the biosynthesis of secondary metabolites than IiPAL2. In conclusion, the present study provides a basis for the elucidation of the role of Ii PALs genes in the biosynthesis of phenolic compounds, which will help further metabolic engineering to improve the accumulation of bioactive components

关键词： Phenylalanine ammonia-lyase Isatis indigotica Fort Phenolic compounds Lignan Correlation analysis

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