Ferritinophagy: A new idea for liver diseases regulated by ferroptosis

作     者：Zi-Bing Qian Jun-Feng Li Wan-Yuan Xiong Xiao-Rong Mao Zi-Bing Qian;Jun-Feng Li;Wan-Yuan Xiong;Xiao-Rong Mao

作者机构：The First Clinical Medical College of Lanzhou UniversityLanzhou 730000China Institute of Infectious DiseasesThe First Hospital of Lanzhou UniversityLanzhou 730000China Department of Infectious DiseaseThe First Hospital of Lanzhou UniversityLanzhou 730000China 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2024年第23卷第2期

页      面：160-170页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：This study was supported by grants from the National Natural Science Foundation of China(82360132) the Natural Science Foundation of Gansu Province(20JR5RA364) the Fund of the First Hospital of Lanzhou University(ldyyyn2020-02,ldyyyn2020-14) Gansu Clinical Medical Research Center of Infection&Liver Diseases(21JR7RA392) the Natural Science Foundation of Gansu Province(21JR1RA070) Lanzhou Science and Technology Planning Project(2023-2-76) 

主　　题：Ferritinophagy Ferroptosis Liver disease 

摘      要：Background:The discovery of regulatory cell death has led to a breakthrough in the therapeutic *** forms of cell death,such as necrosis,apoptosis,pyroptosis,autophagy,and ferroptosis,play an important role in the development of liver *** general,more than one form of cell death pathways is responsible for the disease ***,it is particularly important to study the regulation and interaction of various cell death forms in liver *** sources:We performed a PubMed search up to November 2022 with the following keywords:ferritinophagy,ferroptosis,and liver *** also used terms such as signal path,inducer,and inhibitor to supplement the query ***:This review summarized the basic characteristics of ferritinophagy and ferroptosis and the regulation of ferroptosis by ferritinophagy and reviewed the key targets and treatment strategies of ferroptosis in different liver ***:Ferritinophagy is a potential therapeutic target in ferroptosis-related liver diseases.