Ferritinophagy: A new idea for liver diseases regulated by ferroptosis
作者机构:The First Clinical Medical College of Lanzhou UniversityLanzhou 730000China Institute of Infectious DiseasesThe First Hospital of Lanzhou UniversityLanzhou 730000China Department of Infectious DiseaseThe First Hospital of Lanzhou UniversityLanzhou 730000China
出 版 物:《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志(英文版))
年 卷 期:2024年第23卷第2期
页 面:160-170页
核心收录:
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金:This study was supported by grants from the National Natural Science Foundation of China(82360132) the Natural Science Foundation of Gansu Province(20JR5RA364) the Fund of the First Hospital of Lanzhou University(ldyyyn2020-02,ldyyyn2020-14) Gansu Clinical Medical Research Center of Infection&Liver Diseases(21JR7RA392) the Natural Science Foundation of Gansu Province(21JR1RA070) Lanzhou Science and Technology Planning Project(2023-2-76)
主 题:Ferritinophagy Ferroptosis Liver disease
摘 要:Background:The discovery of regulatory cell death has led to a breakthrough in the therapeutic *** forms of cell death,such as necrosis,apoptosis,pyroptosis,autophagy,and ferroptosis,play an important role in the development of liver *** general,more than one form of cell death pathways is responsible for the disease ***,it is particularly important to study the regulation and interaction of various cell death forms in liver *** sources:We performed a PubMed search up to November 2022 with the following keywords:ferritinophagy,ferroptosis,and liver *** also used terms such as signal path,inducer,and inhibitor to supplement the query ***:This review summarized the basic characteristics of ferritinophagy and ferroptosis and the regulation of ferroptosis by ferritinophagy and reviewed the key targets and treatment strategies of ferroptosis in different liver ***:Ferritinophagy is a potential therapeutic target in ferroptosis-related liver diseases.