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Prognostic value of systemic immune- inflammation index in acute/subacute patients with cerebral venous sinus thrombosis

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Stroke & Vascular Neurology 2020年第4期5卷 368-373页

作者： shen li Kai liu Yuan Gao Lu Zhao Rui Zhang hui fang yongli tao Hongbing liu Jiawei Zhao Zongping Xia Yuming Xu Bo Song Department of Neurology Zhengzhou University First Affiliated HospitalZhengzhouHenanChina

Objective To evaluate the prognosis values of systemic immune-inflammation index(SII)in non-chronic cerebral venous sinus thrombosis(CVST).Methods patients with CVST,admitted to the First Affiliated Hospital of Zhengzhou University,were retrospectively identified from January 2013 to December *** selected patients in acute/subacute phase from *** outcomes of patients were evaluated with the modified Rankin Scale(mRS)-mRS 3-6 as poor outcomes and mRS 6 as *** overall survival time was defined as the date of onset to the date of death or last follow-up *** analysis was described by the Kaplan-Meier curve and Cox regression *** logistic regression analysis assessed the relationship between SII and poor functional *** area under the Receiver Operating Curve curve(AUC)was estimated to evaluate the ability of SII in *** A total of 270 patients were included and their duration of follow-up was 22 months(6-66 months),of whom 31 patients had poor outcomes and 24 patients *** regression analysis showed that SII(HR=1.304,95%CI:1.101 to 1.703,p=0.001)was a predictor of death in non-chronic *** with higher SII presented lower survival rates(p=0.003).The AUC of SII was 0.792(95%CI:0.695 to 0.888,p=0.040)with a sensitivity of 69.6%and specificity of 80.1%.Subgroups analysis demonstrated that SII was an important predictor of poor outcomes in male(OR=1.303,95%CI:1.102 to 1.501,p=0.011)and pregnancy/puerperium female(OR=1.407,95%CI:1.204 to 1.703,p=0.034).Conclusions SII was a potential predictor in the poor prognosis of patients with acute/subacute CVST,especially in male and pregnancy/puerperium female.

关键词： patients inflammation admitted

One-year status of hepatic venous pressure gradient measurement from 85 hospitals in China

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Portal Hypertension & Cirrhosis 2024年第2期3卷 116-123页

作者： Jitao Wang Ting Cui linpeng Zhang Zhiping Yan Lei li Jinjun Chen Junhui Sun Hua Xiang He Zhu Hao Wu Jiancuo Gengzang Feng Zhang Wei Wu Guohong Cao Wuhua Guo Haibin Shi hui Xue guangjun Huang Qiang Yu Meng Niu huiling Xiang Derun Kong Wei Gou Xuefeng Luo Fuliang He Min Yuan Wei liu yong Wang Hongjie Hu Xiaoli Zhu tao Yu Qinxue Sun Wei Qu Ting Lu Deqiang Ma li Zhang Jun Ma Jun Yang Ketao Mu Xiaoliang Zhu Kai Xiong huiguo Ding shengjuan Yao Mingsheng Huang fang Wang Zexin Wang yong Huang Jianan li Hongfeng Yi Birun Huang Zhongwei Zhao duiping Feng Yanming Lei Changlong Hou Wenbo Guo Shirong liu Gaojun Teng Kangshun Zhu Fan Wu Xiaogang Hu Wenfeng Zhang Shaoqi Yang Zhouchao Hu Pengfei Pang Shaowu Zhuang Weidong Wang Qingliang Zhu Kunpeng Zhang Chengyu liu Dongliang li Chao Ma Hong Jiang Xingong Zhao Weixin Ren Zhiwei Wang Lei Yu Fuhuang lin Chaoguang Yan Feng Wang Lei Yu hui Huan Wenyong shen Shaofei He Chengda Zhang Jinlun Bao Jiangtao liu Jun Wu Jianbo Zhao Jian Zhang Xiaolong Qi Hebei Provincial Key Laboratory of Cirrhosis&Portal Hypertension Xingtai People's HospitalXingtaiHebeiChina Center of Portal Hypertension Department of RadiologyZhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsuChina Department of Interventional Therapy Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijingChina Department of Intervention Taiyuan Third People's HospitalTaiyuanShanxiChina Department of Intervention Zhongshan Hospital Affiliated to Fudan UniversityShanghaiChina Department of Interventional Medicine The First Hospital of Lanzhou UniversityLanzhouGansuChina Department of Infectious Diseases Nanfang Hospital of Southern Medical UniversityGuangzhouGuangdongChina Hepatobiliary and Pancreatic Intervention Center The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiangChina Interventional Vascular Surgery Hunan Provincial People's HospitalChangshaHunanChina Department of Intervention Sixth People's Hospital of ShenyangShenyangLiaoningChina Department of Gastroenterology West China Hospital of Sichuan UniversityChengduSichuanChina Department of Intervention The Fourth People's Hospital of Qinghai ProvinceXiningQinghaiChina Department of Gastroenterology Nanjing Drum Tower HospitalNanjingJiangsuChina Department of Gastroenterology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Department of Radiology Shulan(Hangzhou)HospitalHangzhouZhejiangChina Department of Intervention Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouFujianChina Department of Interventional Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxiChina Department of Gastroenterology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinanShandongChina Department of Interventional Radiology Fifth Medical Center

Aims:Surveys and research on the applications of the hepatic venous pressure gradient(HVPG)are important for understanding the current status and future development of this technology in *** article aimed to investigate the status of hepatic venous pressure gradient measurement in China in ***:We investigated the overall status of HVPG technology in China-including hospital distribution,hospital level,annual number of cases,catheters used,average cost,indications,and current challenges by using online *** counting the number and percentages of cases of these results,we hope to clarify the current status of HVPG measurements in ***:According to the survey,85 hospitals in China used HVPG technology in 2022 distributed across 29 provinces.A total of 4989 HVPG measurements were performed in all of the surveyed hospitals in 2022,of which 2813 cases(56.4%)were measured *** average cost of HVPG measurement was 5646.8±2327.9 *** the clinical teams who performed the measurements(sometimes multiple per hospital),94.3%(82/87)used the balloon method,and the majority of the teams(72.4%,63/87)used embolectomy ***:This survey clarified the clinical application status of HVPG in China and confirmed that some medical institutions in China have established a foundation for this *** is still necessary to continue promoting and popularizing this technology in the future.

关键词： application status hepatic vein pressure gradient questionnaire survey

Occupational Exposure to Indium of Indium Smelter Workers

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Biomedical and Environmental Sciences 2016年第5期29卷 379-384页

作者： DING Chun guang WANG Huan Qiang SONG Han Bo li Zhi hui li Xiao Ping YE Shao Se ZHANG Fu Gang CUI Shi Wei YAN hui fang li tao National Institute of Occupational health and Poison Control Chinese Center for Disease Control and Prevention Beijing 100050 China North China University of Science and Technology Tangshan 063009 Hebei China guangxi Zhuang Autonomous Region Academy for the Prevention and Treatment of Occupational Diseases Nanning 530021 Guangxi China

Case reports of indium-related lung disease in workers have raised public concern to the human toxicity of indium （In） and its compounds. However, studies evaluating the exposure or health of workers in In smelting plants are rare. Therefore, in this study, we focused on four In smelting plants, with the main objective of characterizing In in smelter plants in China and discussing the potential exposure biomarkers of In exposure.

关键词： Occupational Exposure to Indium of Indium Smelter Workers than Office In

品种和种植密度对木薯茎叶生物量及营养品质的影响

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饲料研究 2024年第16期47卷 118-124页

作者：宋记明刘光华段春芳姜太玲李月仙肖明昆沈正松严炜热带作物生物育种全国重点实验室云南昆明650205 云南省农业科学院热带亚热带经济作物研究所云南保山678000 云南省农业科学院国际农业研究所云南昆明650205

研究旨在探讨品种和种植密度对木薯茎叶产量、农艺性状及营养品质的影响。以木薯桂热891、云热薯2号、华南205为试验材料,选择品种(A)、种植密度(B)两个因素进行随机区组设计,在云南干热河谷区进行7个种植密度的田间比对试验。结果显示... 详细信息

研究旨在探讨品种和种植密度对木薯茎叶产量、农艺性状及营养品质的影响。以木薯桂热891、云热薯2号、华南205为试验材料,选择品种(A)、种植密度(B)两个因素进行随机区组设计,在云南干热河谷区进行7个种植密度的田间比对试验。结果显示,木薯茎叶产量随种植密度增加呈先升高后下降的趋势,按B6、B5种植可收获较高的茎叶产量,低种植密度比高种植密度更适合茎叶干物质的积累。株高随种植密度的增加呈升高趋势,而茎粗则逐渐下降。根据平均隶属函数结果可知,A1、A3按B4种植营养品质最佳,A2按B2种植营养品质最佳,且粗蛋白含量相对较高。不同品种间,A2、A3的产量、农艺性状、营养品质优于A1。研究表明,云热薯2号为适宜云南干热河谷区种植品种,其适宜种植密度为50 000株/hm2,可收获较高的茎叶生物产量,且营养品质佳。

关键词：品种种植密度木薯茎叶产量

Posterior reversible encephalopathy syndrome and heart failure tacrolimus-induced after liver transplantation: A case report

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World Journal of Clinical Cases 2020年第13期8卷 2870-2875页

作者： Jun-fang liu Tian shen Yun-tao Zhang Division of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003Zhejiang ProvinceChina

BACKGROUND Patients undergoing liver transplantation can develop posterior reversible encephalopathy syndrome(PRES)and acute heart failure(HF)in the postoperative *** PRES with HF caused by tacrolimus has rarely been *** SUMMAR A 40-year-old female patient who had a normal preoperative cardiac and neural evaluation developed PRES with acute heart failure tacrolimus-induced after liver *** challenges associated with both diagnosis and management in the setting of a newly implanted graft are *** Tacrolimus can induce neurotoxicity and then cardiac *** resonance imaging,echocardiography,and increased brain natriuretic peptide may be predictive of post-operative PRES with acute heart *** investigations are necessary to verify this finding.

关键词： liver transplantation Tacrolimus Posterior reversible encephalopathy syndrome Neurologic complications Cardiac toxicity Case report

Dynamically adjustable asymmetric transmission and polarization conversion for linearly polarized terahertz wave

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Chinese Physics B 2020年第2期29卷 288-293页

作者： Tong li fang-Rong Hu Yi-Xian Qian Jing Xiao Long-hui Zhang Wen-tao Zhang Jia-guang Han guangxi Key Laboratory of Optoelectronic Information Processing Guilin University of Electronic TechnologyGuilin 541004China Key Laboratory of Optical Information Detecting and Display Technology Zhejiang Normal UniversityJinhua 321004China Air Force Logistics College Xuzhou 221000China

The asymmetric transmission(AT) and polarization conversion of terahertz(THz) wave play a vital role in future THz communication,spectrum,and information ***,it is very difficult and complicated to actively control the AT of electromagnetic(EM) wave by using traditional ***,we theoretically demonstrate a stereo-metamaterial(stereo-MM) consisting of a layer of metal structure and a layer of phase transition structure with a polyimide spacer in *** performance of the device is simulated by using the finite-integration-technology(FIT).The results show that the AT and polarization conversion of linearly polarized wave can be dynamically controlled in a range of 1.0 THz-1.6 THz when the conductivity c,F of vanadium dioxide(VO2) is changed under the external *** study provides an example of actively controlling of the AT and polarization conversion of the EM wave.

关键词： stereo-metamaterial(stereo-MM) asymmetric transmission(AT) polarization conversion vanadium dioxide(VO2)

基于历史学习和关系注意力的时序知识图谱推理

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计算机技术与发展 2024年第7期34卷 161-167页

作者：黄涛徐芳芳顾进广武汉科技大学计算机科学与技术学院湖北武汉430065 智能信息处理与实时工业系统湖北重点实验室湖北武汉430065

时序知识图谱在传统静态知识图谱上进一步引入了时间维度,由此引出时序知识图谱推理任务,旨在推理未来事件或缺失事实的实体或关系。针对大多数时序知识图谱推理模型存在没有充分利用历史事实和关系关联分析的问题,该文提出一种基于历... 详细信息

时序知识图谱在传统静态知识图谱上进一步引入了时间维度,由此引出时序知识图谱推理任务,旨在推理未来事件或缺失事实的实体或关系。针对大多数时序知识图谱推理模型存在没有充分利用历史事实和关系关联分析的问题,该文提出一种基于历史学习和关系注意力的时序知识图谱推理方法(简称HLRA)。为了充分利用历史事实,使用多层感知机学习历史事实中的时间戳权重,并结合复制模式的思想,编码出具备时间权重的历史语义偏移向量,在此基础上关联查询信息得到历史学习评分。另一方面,使用自注意力机制分析关系间的关联,将计算出的关系间注意力分数作为影响因子,并将之加权到实体预测中得到关系注意力的得分。最终,通过结合两个分数以获得综合的置信分数。在ICEWS18、ICEWS14、YAGO和GDELT等数据集上的实验结果表明,HLRA模型在MRR、Hits@1、Hits@3和Hits@10等评价指标上较次优模型获得1%至4%的提升,有效提升了时序图谱推理的能力,是一种效果更好的模型。

关键词：知识图谱时序推理多层感知机复制模式注意力机制

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模拟极端高原环境对大鼠海马转录组的影响

解剖学报 2024年第4期55卷 445-451页

作者：方璇汪涛程全成刘怀存张艳南燕陈春花张卫光北京大学基础医学院人体解剖学与组织学胚胎学系北京100083 北京大学国际医院北京102206

目的建立极端高原低压低氧环境急性暴露模型,探讨与大鼠学习记忆损伤相关的转录组学的变化。方法选取6周龄、200~250 g健康雄性SD大鼠,分为对照组和高原组。对照组经常压常氧处理(19只),高原组置于低压低氧舱内(19只),模拟8000米海拔高... 详细信息

目的建立极端高原低压低氧环境急性暴露模型,探讨与大鼠学习记忆损伤相关的转录组学的变化。方法选取6周龄、200~250 g健康雄性SD大鼠,分为对照组和高原组。对照组经常压常氧处理(19只),高原组置于低压低氧舱内(19只),模拟8000米海拔高度,处理72 h。每组取16只,利用场景恐惧和Morris水迷宫实验(各8只)检测行为学变化。每组取3只,全部海马组织提取RNA行转录组学测序,通过基因本体论(GO)、京都基因与基因组百科全书(KEGG)和基因集富集分析(GSEA)分析极端高原环境诱导学习记忆损伤的分子机制。结果行为学结果显示,与对照组相比,高原组大鼠恐惧记忆和空间学习记忆能力下降。GO和KEGG分析显示,极端高原环境重塑海马组织微环境,影响细胞间信号传递,GSEA显示,极端高原环境上调与质膜和细胞外基质相关的基因集。结论8000米海拔的极端高原环境通过影响大鼠海马组织微环境,破坏细胞间连接,损害细胞间通讯,进而诱导学习记忆功能损伤。

关键词：高原低压低氧学习记忆微环境细胞通讯 Morris水迷宫实验大鼠

Influence of the Energy Level Matching on the Performances of Organic/Polymeric Electroluminescent Devices

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Chinese Physics Letters 1996年第10期13卷 790-793页

作者： TIAN Wen-jing HUANG Jin-song WU fang SUN Chang-qing liu Xiao-dong MA Yu-guang liu Shi-yong shen Jia-cong Key Laboratory of Molecular Spectra and Structures Jilin UniversityChangchun 130023 National Laboratory of Integrated Optic Electronics Jilin UniversityChangchun 130023 Chemical Department Jilin UniversityChangchun 130023 Basic Medical College Norman Bethum University of medical ScienceChangchun 130023

The performances such as the operating-voltage and the brightness of three types of devices: single-layer device, double-layer device and three-layer device, were examined. It is demonstrated that the I-V characteristics of single-layer device depends not on the applied voltage but instead on the electric-field strength, and the brightness increased by a factor of 50 and the operating-voltage decreased when introducing one electron transporting layer or an electron transporting layer and one hole blocking layer between the light emitting layer and the negative electrode. In fact, it is imperative to match the energy level of each layer in the electroluminescent device in order to improve its comprehensive performances.

关键词： Matching Electroluminescent layer