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Orthodontic treatment combined with 3D printing guide plate implant restoration for edentulism and its influence on mastication and phonic function

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World Journal of Clinical Cases 2022年第16期10卷 5297-5305页

作者： li-bo yan Yu-Chao Zhou yang Wang li-Xin li The Outpatient Department Lintong Rehabilitation and Convalescent CenterXi’an 710000Shaanxi ProvinceChina Department of Administration Lintong Rehabilitation and Convalescent CenterXi’an 710000Shaanxi ProvinceChina

BACKGROUND Dentition defect,a common clinical oral disease developed in humans,not only causes masticatory dysfunction and articulation difficulties but also affects facial appearance and increases the burden on the intestinal *** treatment is the primary option for this ***,traditional restorations have many drawbacks,such as mismatch with the body,low reliability,and incomplete occlusal function *** to analyze the efficacy of orthodontics combined with 3D printing guide plate implant restoration in treating patients with dentition defects and its influence on masticatory and phonic *** A prospective study was carried out in 86 patients with dentition defects who received implant prosthesis after orthodontic treatment in our hospital between January 2018 and January *** patients were divided into a control group and an intervention group with 43 patients in each group using a random number *** control group received traditional implant restoration,whereas the intervention group received 3D printing guide plate implant *** outcomes,cosmetic appearance,dental function,implant deviation,and quality of life were compared between the two *** The overall response rate in the intervention group was significantly higher than that in the control group(95.35%vs 81.40%,χ^(2)=4.071,P=0.044).The number of cases with neatly trimmed cosmetic appearance(χ^(2)=4.497,P=0.034),complete coverage(χ^(2)=4.170,P=0.041),and normal occlusion(χ^(2)=5.512,P=0.019)in the intervention group was higher than that in the control *** treatment,mastication,swallowing,and articulation were significantly improved in both ***(t=2.980,P=0.004),swallowing(t=2.199,P=0.031),and phonic functions(t=3.950,P=0.004)were better in the intervention group than those in the control *** deviation value and the deviation angle(t=5.440,P=0.000)at the top(t=6.320,P=0.000)and middle parts of the impla

关键词： Dentition defect Orthodontics 3D printing guide plate implant restoration Masticatory function Phonic function

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Jordan Left Derivations of Generalized Matrix Algebras

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Communications in Mathematical Research 2014年第4期30卷 301-306页

作者： li Chen-Fang li yan-bo School of Mathematics and Statistics Northeastern University at Qinhuangdao

In this paper, it is proved that under certain conditions, each Jordan left derivation on a generalized matrix algebra is zero and each generalized Jordan left derivation is a generalized left derivation.

关键词： generalized Jordan left derivation Jordan left derivation generalized matrix algebra generalized left derivation

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A new convenient asymmetric approach to herbarumin Ⅲ

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Chinese Chemical Letters 2007年第3期18卷 255-257页

作者： Xue Song Chen Shi Jun Da li Hong yang bo yan Xu Ztfi Xiang Xie Ying li The State Key Laboratory of Applied Organic Chemistry Institute of Organic Chemistry Lanzhou University Lanzhou 730000 China

The asymmetric total synthesis of herbarumin Ⅲ 3, a naturally occurred phytotoxin, along with 8-epi-herbantmin Ⅲ 22, was succeeded in 12 steps from n-butyraldehyde based on Brown＇s asymmetric allylation, taking mod... 详细信息

关键词： Herbarumin Ⅲ Asymmetric allylation Modified Julia olefination Yamaguchi's macro-lactonization

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Sn doped ZnO thin films as high resistivity window layer for Cu(In,Ga)Se2 solar cells

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Optoelectronics Letters 2020年第6期16卷 451-454页

作者： li bo-yan liU Fang-fang liN lie Institute of Modern Optics College of Electronic Information and Optical EngineeringNankai UniversityTianjin 300350China Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin Nankai University Tianjin 300350China Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin Tianjin 300350China

For high efficiency Cu(In,Ga)Se2(CIGS) solar cell, the high-resistivity layer with high optical transmittance has to be adopted between the buffer layer and the high-conductivity window layer. In this paper, we propose Sn doped ZnO(ZTO) film, instead of the traditional intrinsic ZnO(i-ZnO) film, as an alternative n-type high-resistivity window layer for CIGS solar cell. In this experiment, both ZTO and i-ZnO films are strong(002) oriented, and the surface morphologies of the two films are almost the same. The statistical roughnesses of i-ZnO film and ZTO film are 0.58 nm and 0.63 nm, respectively. However, the optical transmittance of ZTO film is higher than that of i-ZnO film with the same thickness. The efficiency of ZTO based CIGS cell was 14.24%, which is almost the same as the efficiency of i-ZnO based CIGS cell. These results fully suggest that it is very feasible to replace i-ZnO with ZTO as the high resistant window layer.

关键词： CIGS resistivity layer

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Long-term follow-up of HCV patients with sustained virological response after treatment with pegylated interferon plus ribavirin

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Hepatobiliary & Pancreatic Diseases International 2021年第2期20卷 137-141页

作者： Yuan-Ji Ma ling-Yao Du li-bo yan Juan liao Xing Cheng Wu-Wei Xie Hong Tang Center of Infectious Diseases West China Hospital of Sichuan UniversityChengdu 610041China

Background:The progress of liver diseases may not stop after viral *** study aimed to provide data on long-term prognosis of patients with hepatitis C virus(HCV)infection who underwent pegylated interferon plus ribavirin(PR)regimen and achieved a sustained virological response 24 weeks post-treatment(SVR24).Methods:Responders to the PR regimen in our hospital from January 2011 to June 2014 were enrolled and prospectively followed *** characteristics were *** incidence of hepatocellular carcinoma(HCC),progression of liver disease(increase in liver stiffness or occurrence of decompensated complication),and HCV recurrence was all *** accumulative and annualized incidence rates(AIRs)of these adverse events were analyzed,and the risk factors were also ***:In total,151 patients reached a median follow-up time of 103 *** them,two had an incidence of HCC during the surveillance with AIR of 0.68%(95%CI:0.00-1.63%).Six patients showed progression of liver disease with AIR of 2.05%(95%CI:0.42%-3.68%).Three patients who had risky behaviors encountered HCV *** cirrhotic patients faced higher risk of poor prognosis than non-cirrhotic patients,including HCC and progression of liver disease(AIR:6.17%vs.1.42%,P=0.039).Conclusions:The incidence of HCC and progression of liver disease was evident in PR responders during the long-term follow-up period,but the risk level was *** responders were more vulnerable to develop HCC post SVR24 compared with non-cirrhotic *** recurrence was rare in responders with SVR24 who had corrected their risky behaviors.

关键词： Hepatitis C virus Sustained virological response Hepatocellular carcinoma

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Numerical simulation study on the thermal environment in heading face

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Journal of Coal Science & Engineering(China) 2010年第3期16卷 272-276页

作者： ZHAO Fu-jun HUANG Shou-yuan SHEN Pei-wen li yan-bo . School of Energy and Safety Engineering Hunan University of Science and Technology Xiangtan 411201 China Hunan Provincial Key Laboratory of Mine Safety ＆ Mining Technology Xiangtan 411201 China

Based on κ-ε turbulence model, the distributions of the velocity field, tempera- ture field, thermal comfort index, PMV-PPD （Predicted Mean Vote-Predicted Percentage Dissatisfied）, and air quality index, mean age of air were obtained of Zhouyuanshan Coal Mine in -650 m level of a heading face by CFD（Computational Fluid Dynamics）software, Airpak 2.0. Moreover, the human thermal comfort and the air quality of the heading face were analyzed with PMV-PPD and mean age of air indices, which received an intuitive visualization and accurate evaluation results. In order to create a safe, comfortable, and economical underground operating environment, a scientific, rational, and comprehensive prediction and evaluation needed to provide a theoretical and technical basis for coal mine ventilation, cooling, heat harm treatment, and prevention. Meanwhile, from the human thermal comfort and air quality to research the underground environment, it embodied the concept of being human oriented.

关键词： thermal environment heading face thermal comfort predicted mean vote- predicted percentage dissatisfied indices mean age of air

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Effects of RNA interference-induced tryptase down-regulation in P815 cells on IL-6 and TNF-α release of endothelial cells

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第8期9卷 656-661页

作者： Yi-feng JIANG Feng-di ZHAO Xiao-bo li yan-xia NING Xiu-ling ZHI Rui-zhe QIAN lian-hua YIN Department of Physiology and Pathophysiology Shanghai Medical College Fudan University Shanghai 200032 China

Objective： To explore the effects of down-regulated tryptase expression in mast cells on the synthesis and release of interleukin-6 （IL-6） and tumor necrosis factor-alpha （TNF-α） of vascular endothelial cells. Methods： Tryptase-siRNA （small-interfering RNA） vector was constructed to inhibit tryptase expression in P815 cells. The medium of P815 cells treated by the tryptase-siRNA （RNAi-P815 group） or pure vector （P815 group） was collected and used to culture bEnd.3 cells. The messenger RNAs （mRNAs） of IL-6 and TNF-α in bEnd.3 cells and their protein levels in the medium were measured by reverse transcription polymerase chain reaction （RT-PCR） and enzyme-linked immunosorbent assay （EliSA）, respectively. Results： IL-6 and TNF-α mRNAs in bEnd.3 cells cultured in RNAi-P815-conditioned medium decreased significantly compared to those in P815-conditioned medium. Consistently, lL-6 and TNF-α protein levels in the medium of bEnd.3 of RNAi-P815 group were lower than those of P815 group. Conclusion： Reduced tryptase expression significantly inhibited the synthesis and release of IL-6 and TNF-α in vascular endothelial cells. RNA interference targeting tryptase expression may be a new anti-inflammatory strategy for vascular diseases.

关键词： Tryptase RNA interference lnterleukin-6 (IL-6) Tumor necrosis factor-alpha (TNF-α) Endothelial cells

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Cytotoxicity and DNA Damage Effect of TGA-capped CdTe Quantum Dots

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Chemical Research in Chinese Universities 2012年第2期28卷 276-281页

作者： li yan-bo ZHANG Hai-xia GUO Cai-xia HU Gui-qin DU Hai-ying JIN Ming-hua HUANG Pei-li SUN Zhi-wei yanG Wen-sheng School of Public Health and Family Medicine Capital Medical UniversityBeijing 100069P.R.China Public Health Institute Beijing Chaoyang District Centre for Disease Control and PreventionBeijing 100021P R.China School of Public Health Jilin UniversityChangchun 130021P.R.China Key Laboratory of Surface and Interface Chemistry of Jilin Province College of ChemistryJilin UniversityChangchun 130012P.R.China

The cytotoxicity and DNA damage caused by thioglycolic acid（TGA）-capped cadmium telluride（CdTe） quantum dots（QDs） to hepatocyte line HL-7702 were *** viability was measured by 3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyltetrazolium bromide（MTT） assay;DNA damage was detected by single cell gel electrophoresis（SCGE）;the change of cell cycle progression was examined by propidium iodide（PI）-flow cytometry（FCM）;apoptosis was measured by acridine orange/ethidium bromide（AO/EB） assay and Annexin V-FITC/PI-FCM（FITC：fluorescein isothiocyanate）.The results show that the cytotoxicity induced by CdTe QDs was increased in a dose-dependent and time-dependent manner;after exposure to QDs for 24 h,as the exposure dose increased,the rate of DNA damage was significantly increased（P0.05）,and the degree of DNA damage was *** the dose of CdTe QDs increased,the percentage of G 0 /G 1 phase cells was significantly decreased（P0.001）,while the percenttages of S and G 2 /M phases cells were significantly increased（P0.001）.In AO/EB assay,apoptotic cells could be observed under a fluorescence microscope,and apoptotic rate was increased as exposure dose *** Annexin V-FITC/PI-FCM assay,the apoptotic rates of CdTe QDs treated groups were significantly increased compared with that of control group（P0.05）.Our studies indicate that CdTe QDs could influence cell viability,and induce DNA damage,the S and G2 /M phases arrest and apoptosis of HL-7702.

关键词： Apoptosis CdTe quantum dot(QD) Cell cycle Cell viability DNA damage

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Overexpression of transcription factor EB regulates mitochondrial autophagy to protect lipopolysaccharide-induced acute lung injury

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Chinese Medical Journal 2019年第11期132卷 1298-1304页

作者： Wei liu Cong-Cong li Xi Lu li-yan bo Fa-Guang Jin Departm ent of Respiratory The Second Affiliated Hospital The Air Force Military Medical University Xi'an Shaanxi 710038 China Department of Respiratory The General Hospital of Northern Theater Shenyang Liaoning 110000 China

Background:Acute lung injury (Ali) is characterized by an acute inflammatory process, and oxidative stress in the lung tissue leads to a lack of effective therapeutics. This study aimed to identify whether the overexpression of transcription factor EB (TFEB) regulates mitophagy to protect against lipopolysaccharide (LPS)-induced Ali. Methods: We detected the expression of inflammatory factors, cytochrome c (Cyt.c) and nicotinamide adenine dinucleotide phosphate (NADPH), and autophagy-related proteins and observed the changes in lung histopathology induced by Ali in rats and the changes in the cell ultrastructure of primary alveolar type II epithelial cells induced by changing the expression of TFEB in the context of Ali. Results: The overexpression of TFEB could reduce the expression of proinflammatory factors, such as IL-1 and IL-6, and increase the expression of anti-inflammatory factors, such as IL-10, both in vitro and in vivo. In addition, the overexpression of TFEB could reduce the Cyt.c and NADPH levels both in vivo and in vitro. The overexpression of TFEB could upregulate the expression of autophagy-related proteins, such as lysosomal-associated membrane protein 1 (LAMP1), microtubule-associated protein light chain 3B (LC3B), and Beclin both in vivo and in vitro^ and promote mitochondrial autophagy. The overexpression of TFEB significantly improved the histopathologic changes induced by LPS-induced Ali in rats. However, low TFEB expression produced the opposite results. Conclusion: TFEB overexpression can decrease inflammation and mitochondrial damage in the lung tissue and alveolar epithelial cells through regulating mitochondrial autophagy to protect against LPS-induced Ali. Therefore, TFEB is likely a potential therapeutic target in LPS-induced Ali.

关键词： Transcription factor EB Mitochondrial autophagy Acute lung injury Inflammation Mitochondrial damage

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Polyetherketoneketone/carbon fiber composites with an amorphous interface prepared by solution impregnation

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新型炭材料（中英文） 2024年第4期39卷 692-702页

作者： ZHANG Feng li bo-lan JIAO Meng-xiao li yan-bo WANG Xin yanG Yu yanG Yu-qiu ZHANG Xiao-hua MOE Key Laboratory of Textile Science&Technology College of TextilesInnovation Center for Textile Science and TechnologyDonghua UniversityShanghai 201620China Key Laboratory of Carbon Materials National Engineering Laboratory for Carbon Fiber TechnologyInstitute of Coal ChemistryChinese Academy of SciencesTaiyuan 030001China

Interfacial adhesion between carbon fibers(CF)and polyetherketoneketone(PEKK)is a key factor that affects the mechanical performances of their *** is therefore of great importance to impregnate the CF bundles with PEKK as effi-ciently as *** report that PEKK with a good dispersion in a mixed solution of 4-chlorophenol and 1,2-dichloroethane can be introduced onto CF surfaces by solution impregnation and curing at 280,320,340 and 360℃.The excellent wettability or infiltra-tion of the PEKK solution guarantees a full covering and its tight binding to CFs,making it possible to evaluate the interfacial shear strength(IFSS)with the microdroplet *** interior of the CF bundles is completely and uniformly filled with PEKK by solu-tion impregnation,leading to a high interlaminar shear strength(ILSS).The maximum IFSS and ILSS reached 107.8 and 99.3 MPa,*** superior shear properties are ascribed to the formation of amorphous PEKK in the small spaces between CFs.

关键词： Polyetherketoneketone Carbon fiber Wettability Amorphous adhesion Interfacial strength

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