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Efficacy of Chaihu Jisang decoction on post-infection cough and its effect on cough reflex sensitivity

Journal of Traditional Chinese Medicine 2018年第4期38卷 610-617页

作者： Hong Minli Huang Baopei Hong Chunlin Chen Huinuan Chen Wenxi liu Chaohui li xinjian li Candong Traditional Chinese Medicine Syndrome Research Institution Fujian University of Traditional Chinese Medicine Department of Respiratory Medicine Zhangzhou Affiliated Traditional Chinese Medicine Hospital of Fujian University of Traditional Chinese Medicine Department of Respiratory Medicine Fujian Province Zhangping Municipal Hospital Clinical laboratory Zhangzhou Affiliated Traditional Chinese Medicine Hospital of Fujian University of Traditional Chinese Medicine Orthopedics Department of Traditional Chinese Medicine Beijing Sports University Hospital

OBJECTIVE:To investigate the efficacy of Chaihu Ji Sang Decoction(CJSD),(a modification of Xiao Chaihu Tang(Minor Decoction of Bupleurum) was evaluated in patients with post-infection cough(PIC).Its effect on cough reflex sensitivity(CRS) was also ***:One hundred and eighteen patients with PIC were enrolled and randomly divided into an experimental group and control group(54 patients in each group).The experimental group was given CJSD orally,and the control group was given cetirizine hydrochloride for 7 *** symptom scores and TCM symptom scores were compared before and after ***,cough onset time,recurrence,and adverse drug reactions were additionally ***,CRS was evaluated before and after treatment of PIC patients in the experimental ***:Fifty-two patients in the experimental group and fifty control patients completed the *** symptom scores and the TCM symptom scores of the two groups were significantly improved after treatment,however cough symptoms in the experimental group 1(0,2) were significantly lower than the control group 2(1,2) after treatment(P < 0.05).Similarly,TCM symptom scores 4(0,7) in the experimental group were significantly lower than the control group 6(3,12)(P < 0.01).Overall,the effective rate of the experimental treatment(84.60%) was significantly higher than that of the control treatment(68.00%)(P < 0.01).The onset time of efficacy of the experimental treatment was one day faster than the control treatment [2(2,3) d vs 3(2,3) d,P < 0.01].The relapse rate in the experimental group(9.09%) was lower than that of the control group(29.41%)(P < 0.05).39 PIC patients in the experimental group completed a capsaicin cough challenge test before *** lgC2 and lg C5 of the experimental group prior to treatment was 1.19(0.59,1.49) and 1.80(1.49,2.10),*** lgC2,lg C5 of the healthy control group was 1.49(0.89,2.40) and 2.70(2.40,3.00),*** differences in lgC2

关键词： Post-infection cough Chaihu Jisang decoction Efficacy Cough reflex sensitivity Capsaicin cough challenge test

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Lanthanide-based ratiometric luminescence nanothermometry

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Nano Research 2023年第2期16卷 2949-2967页

作者： Mochen Jia Xu Chen Ranran Sun Di Wu xinjian li Zhifeng Shi Guanying Chen Chongxin Shan Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage School of Chemistry and Chemical Engineering&Key Laboratory of Micro-systems and Micro-structuresMinistry of EducationHarbin Institute of TechnologyHarbin 150001China

Luminescent nanothermometry can precisely and remotely measure the internal temperature of objects at nanoscale precision,which,therefore,has been placed at the forefront of scientific *** particular,due to the high photochemical stability,low toxicity,rich working mechanisms,and superior thermometric performance,lanthanide-based ratiometric luminesencent thermometers are finding prevalent uses in integrated electronics and optoelectronics,property analysis of in-situ tracking,biomedical diagnosis and therapy,and wearable e-health *** recent progresses,it remains debate in terms of the underlying temperature-sensing mechanisms,the quantitative characterization of performance,and the reliability of temperature *** this review,we show the origin of thermal response luminescence,rationalize the ratiometric scheme or thermometric mechanisms,delve into the problems in the characterization of thermometric performance,discuss the universal rules for the quantitative comparison,and showcase the cutting-edge design and emerging applications of lanthanide-based ratiometric ***,we cast a look at the challenges and emerging opportunities for further advances in this field.

关键词： luminescent nanothermometry lanthanide ions ratiometric thermometers thermal imaging

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Doping suppresses lattice distortion of vacant quadruple perovskites to activate self-trapped excitons emission

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Nano Research 2024年第4期17卷 3068-3078页

作者： Zhipeng Chen Fei Zhang Dongwen Yang Huifang Ji Xu Chen Di Wu xinjian li Yu Zhang Zhifeng Shi Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China State Key Laboratory on Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012China

The vacancy-ordered quadruple perovskite Cs_(4)CdBi_(2)Cl_(12),as a newly-emerging lead-free perovskite system,has attracted great research interest due to its excellent stability and direct band ***,the poor luminescence performance limits its application in light-emitting diodes(LEDs)and other ***,for the first time,an Ag^(+)ion doping strategy was proposed to greatly improve the emission performance of Cs_(4)CdBi_(2)Cl_(12) synthesized by hydrothermal *** functional theory calculations combined with experimental results evidence that the weak orange emission from Cs_(4)CdBi_(2)Cl_(12) is attributed to the phonon scattering and energy level crossing due to the large lattice distortion under excited ***,Ag^(+)ion doping breaks the intrinsic crystal field environment of Cs_(4)CdBi_(2)Cl_(12),suppresses the crossover between ground and excited states,and reduces the energy loss in the form of nonradiative *** a critical doping amount of 0.8%,the emission intensity of Cs_(4)CdBi_(2)Cl_(12):Ag^(+)reaches the maximum,about eight times that of the pristine ***,the doped Cs_(4)CdBi_(2)Cl_(12) still maintains excellent stability against heat,ultraviolet irradiation,and environmental oxygen/*** above advantages make it possible for this material to be used as solid-state phosphors for white LEDs applications,and the Commission International de I’Eclairage color coordinates of(0.31,0.34)and high color rendering index of 90.6 were *** importantly,the white LED demonstrates remarkable operation stability in air ambient,showing almost no emission decay after a long working time for 48 *** believe that this study puts forward an effective ion-doping strategy for emission enhancement of vacancy-ordered quadruple perovskite Cs_(4)CdBi_(2)Cl_(12),highlighting its great potential as efficient emitter compatible for practical applications.

关键词： Cs_(4)CdBi_(2)Cl_(12) self-trapped excitons ion doping emission enhancement stability

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In situ construction of PtSe_(2)/Ge Schottky junction array with interface passivation for broadband infrared photodetection and imaging

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InfoMat 2024年第4期6卷 37-46页

作者： Xue li Shuo-En Wu Di Wu Tianxiang Zhao Pei lin Zhifeng Shi Yongtao Tian xinjian li Longhui Zeng Xuechao Yu School of Physics and Microelectronics Key Laboratory of Material Physics Ministry of EducationZhengzhou UniversityZhengzhouHenanthe People's Republic of China Department of Electrical and Computer Engineering University of CaliforniaLa JollaCaliforniaUSA National Research Center for Optical Sensors/Communications Integrated Networks School of Electronic Science and EngineeringSoutheast UniversityNanjingJiangsuthe People's Republic of China Key Laboratory of Multifunctional Nanomaterials and Smart Systems Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhouJiangsuthe People's Republic of China

Infrared(IR)detection is vital for various military and civilian *** research has highlighted the potential of two-dimensional(2D)topological semimetals in IR detection due to their distinctive advantages,including van der Waals(vdW)stacking,gapless electronic structure,and Van Hove singularities in the electronic density of ***,challenges such as large-scale patterning,poor photoresponsivity,and high dark current of photodetectors based on 2D topological semimetals significantly impede their wider applications in low-energy photon ***,we demonstrate the in situ fabrication of PtSe_(2)/Ge Schottky junction by directly depositing 2D PtSe_(2) films with a vertical layer structure on a Ge substrate with an ultrathin AlOx *** to high quality junction,the photodetector features a broadband response of up to 4.6μm,along with a high specific detectivity of�1012 Jones,and operates with remarkable stability in ambient conditions as ***,the highly integrated device arrays based on PtSe_(2)/AlOx/Ge Schottky junction showcases excellent Mid-IR(MIR)imaging capability at room *** findings highlight the promising prospects of 2D topological semimetals for uncooled IR photodetection and imaging applications.

关键词： broadband photodetection imaging platinum diselenide Schottky junction van der Waals integration

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Recent Advances and Opportunities of Lead-Free Perovskite Nanocrystal for Optoelectronic Application

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Energy Material Advances 2021年第1期2021卷 295-332页

作者： Fei Zhang Zhuangzhuang Ma Zhifeng Shi Xu Chen Di Wu xinjian li Chongxin Shan Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China

Metal halide perovskite nanocrystals(NCs),as a new class of light-emitting and light-harvesting materials,have recently attracted intensive attention for an impressive variety of optoelectronic ***,the lead toxicity and poor stability of such materials severely restrict their practical applications and future ***-free perovskite NCs and their derivatives,designed by the reasonable chemical substitution of Pb with other nontoxic elements,are recently booming as an attractive alternative to lead-based *** this review,we firstly present a comprehensive overview of currently explored lead-free perovskite NCs with an emphasis on their design routes,morphologies,optoelectronic properties,and environmental stability ***,we discuss the preliminary achievements of lead-free perovskite NCs in versatile optoelectronic applications,such as light-emitting devices,solar cells,photodetectors,and *** finish this review with a critical outlook into the currently existing challenges and possible development opportunities of this rapidly evolving field.

关键词： field. perovskite stability

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Robust frequency-upconversion lasing operated at 400 K from inorganic perovskites microcavity

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Nano Research 2022年第1期15卷 492-501页

作者： Zhifeng Shi Fei Zhang Jingjing Yan Yuan Zhang Xu Chen Shu Chen Di Wu xinjian li Yu Zhang Chongxin Shan Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China State Key Laboratory on Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityQianjin Street 2699Changchun 130012China

Multi-photon-pumped lasing based on metal-halide perovskites is promising for nonlinear optics and practical frequency-upconversion devices in integrated photonic ***,at present almost all the multi-photon-pumped lasing emissions from perovskite microcavities were limited for two-photon excitation,and also suffered from a compromise in room temperature or low temperature operation *** this study,based on the vapor-phase epitaxial CsPbBr3 microplatelets with high crystallinity,self-formed high-quality microcavities,and great thermal stability,low-threshold and high-quality factor whispering gallery mode lasing was realized under single-,two-,and three-photon excitation,and the lasing action is very stable under continuous pulsed laser irradiation(~3.6×10^(7) laser shots).More importantly,the three-photon-pumped lasing can be efficiently sustained at a high temperature of~400 K,and the characteristic temperature was determined to be as high as~152.6 K,indicating the highly temperature-insensitive gain *** that this is the first report on high-temperature three-photon-pumped lasing on perovskite ***,an aggressive thermal cycling test(two cycles,290-400-290 K)was further performed to indicate the stability and repeatability of the multi-photon-pumped lasing *** can be anticipated that the results obtained represent a significant step toward the temperature-insensitive frequency-upconversion lasing,inspiring the exploitation of advantageous perovskites for novel applications.

关键词： frequency-upconversion lasing perovskite microcavity high-temperature characteristic temperature stability

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Three-dimensional Au/carbon nanotube-graphene foam hybrid nanostructure for dendrite free sodium metal anode with long cycle stability

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Journal of Materials Science & Technology 2022年第23期118卷 128-136页

作者： Zhenxin Huang Zixuan Wang Bofang Tian Tingting Xu Caiyun Ma Zhuangfei Zhang Jinhao Zang Dezhi Kong xinjian li Ye Wang Key Laboratory of Material Physics Ministry of EducationSchool of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China

Sodium metal anode has been attracting widely research attention due to its large capacity and low electrode potential as the anode of sodium-ion ***,the uncontrollable growth of Na dendrite is one of the critical issues for its real ***,a three-dimensional(3 D) nanostructure composed of gold nanoparticles(Au NPs) supported on 3 D carbon nanotube-graphene foam(3 D CNT-GF)was designed and fabricated as the host of sodium metal ***@3 D Au/CNT-GF anode can deliver a Coulombic efficiency of 99.14% and stably cycle for 2600 h at 1 mA cm^(-2) with 1 mAh cm^(-2).It can cycle for 300 h at 5 mA cm^(-2) with 1 mAh cm^(-2).Detailed results indicate that its excellent electrochemical performance can be attributed to the unique macroporous structure and sodiophilic surface formed by Au NPs guiding the uniform sodium metal deposition enabled a dendrite-free morphology investigated by the ex-situ SEM and in-situ optical *** last,a full cell was assembled with Na@3 D Au/CNT-GF as the anode and Na_(3) V_(2)(PO_(4))_(3)@C as the *** can deliver a capacity of 84.6 mAh g^(-1) at 100 mA g^(-1)after 200 *** results demonstrate that 3 D Au/CNT-GF is a promising sodium metal anode host.

关键词： 3D Au/CNT-GF Sodiophilic Au NPs Dendrite free Uniform deposition In-situ optical microscopy investigation

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Van der Waals integration inch-scale 2D MoSe_(2) layers on Si for highly-sensitive broadband photodetection and imaging

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Nano Research 2023年第8期16卷 11422-11429页

作者： Yupiao Wu Shuo-En Wu Jinjin Hei Longhui Zeng Pei lin Zhifeng Shi Qingming Chen xinjian li Xuechao Yu Di Wu School of Physics and Microelectronics and Key Laboratory of Material PhysicsZhengzhou UniversityZhengzhou 450052China Department of Electrical and Computer Engineering University of California San DiegoLa JollaCA 92093USA School of Microelectronics Science and Technology Sun Yat-Sen UniversityZhuhai 519082China Key Laboratory of Multifunctional Nanomaterials and Smart Systems Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China

As one of the most promising materials for two-dimensional transition metal chalcogenides(2D TMDs),molybdenum diselenide(MoSe_(2))has great potential in photodetectors due to its excellent properties like tunable bandgap,high carrier mobility,and excellent air *** 2D MoSe_(2)-based photodetectors have been reported to exhibit admired performance,the large-area 2D MoSe_(2)layers are difficult to be achieved via conventional synthesis methods,which severely impedes its future ***,we present the controllable growth of large-area 2D MoSe_(2)layers over 3.5-inch with excellent homogeneity by a simple post-selenization ***,a high-quality n-MoSe_(2)/p-Si van der Waals(vdW)heterojunction device is in-situ fabricated by directly growing 2D n-MoSe_(2)layers on the patterned p-Si substrate,which shows a self-driven broadband photoresponse ranging from ultraviolet to mid-wave infrared with an impressive responsivity of 720.5 mA·W^(−1),a high specific detectivity of 10^(13) Jones,and a fast response time to follow nanosecond pulsed optical *** addition,thanks to the inch-level 2D MoSe_(2)layers,a 4×4 integrated heterojunction device array is achieved,which has demonstrated good uniformity and satisfying imaging *** large-area 2D MoSe_(2)layer and its heterojunction device array have great promise for high-performance photodetection and imaging applications in integrated optoelectronic systems.

关键词： molybdenum diselenide large-area synthesis broadband photodetector integrated device array van der Waals(vdW)heterojunction

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In-situ fabrication of on-chip 1T'-MoTe_(2)/Ge Schottky junction photodetector for self-powered broadband infrared imaging and position sensing

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Nano Research 2024年第6期17卷 5587-5594页

作者： Menglei Zhu Kunxuan liu Di Wu Yunrui Jiang Xue li Pei lin Zhifeng Shi xinjian li Ran Ding Yalun Tang Xuechao Yu Longhui Zeng School of Physics and Microelectronics and Key Laboratory of Material PhysicsZhengzhou UniversityZhengzhou 450052China Department of Electrical and Computer Engineering University of California San DiegoLa JollaCA 92093USA State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012China Key Laboratory of Multifunctional Nanomaterials and Smart Systems Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China

High-sensitivity room-temperature multi-dimensional infrared(IR)detection is crucial for military and civilian ***,the gapless electronic structures and unique optoelectrical properties have made the two-dimensional(2D)topological semimetals promising candidates for the realization of multifunctional optoelectronic ***,we demonstrated the in-situ construction of high-performance 1T’-MoTe_(2)/Ge Schottky junction device by inserting an ultrathin AlOx passivation *** good detection performance with an ultra-broadband detection wavelength range of up to 10.6 micron,an ultrafast response time of~160 ns,and a large specific detectivity of over 109 Jones in mid-infrared(MIR)range surpasses that of most 2D materials-based IR sensors,approaching the performance of commercial IR *** on-chip integrated device arrays with 64 functional detectors feature high-resolution imaging capability at room *** these outstanding detection features have enabled the demonstration of position-sensitive detection *** demonstrates an exceptional position sensitivity of 14.9 mV/mm,an outstanding nonlinearity of 6.44%,and commendable trajectory tracking and optoelectronic demodulation *** study not only offers a promising route towards room-temperature MIR optoelectronic applications,but also demonstrates a great potential for application in optical sensing systems.

关键词： MoTe_(2) broadband photodetection Schottky junction imaging position sensitive detector

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Fabricating Na/In/C Composite Anode with Natrophilic Na-In Alloy Enables Superior Na Ion Deposition in the EC/PC Electrolyte

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Nano-Micro Letters 2022年第2期14卷 45-59页

作者： Hui Wang Yan Wu Ye Wang Tingting Xu Dezhi Kong Yang Jiang Di Wu Yongbing Tang xinjian li Chun-Sing Lee Key Laboratory of Material Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052People’s Republic of China Department of Chemistry Center of Super‑Diamond and Advanced Films(COSDAF)City University of Hong KongHong Kong SAR 999077People’s Republic of China School of Materials Science and Engineering Hefei University of TechnologyHefei 230009AnhuiPeople’s Republic of China Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen 518055People’s Republic of China

In conventional ethylene carbonate(EC)/propylene carbonate(PC)electrolyte,sodium metal reacts spontaneously and deleteriously with solvent *** significantly limits the practical feasibility of high-voltage sodium metal batteries based on Na metal ***,we present a sodium metal alloy strategy via introducing NaIn and Na_(2)In phases in a Na/In/C composite,aiming at boosting Na ion deposition stability in the common EC/PC *** cells with Na/In/C electrodes achieve an impressive long-term cycling capability at 1 mA cm^(-2)(>870 h)and 5 mA cm^(-2)(>560 h),respectively,with a capacity of 1 mAh cm^(-2).In situ optical microscopy clearly unravels a stable Na ion dynamic deposition process on the Na/In/C composite electrode surface,attributing to a dendrite-free and smooth ***,theoretical simulations reveal intrinsic mechanism for the reversible Na ion deposition behavior with the composite Na/In/C *** pairing with a highvoltage NaVPOF cathode,Na/In/C anode illustrates a better suitability in SMB *** work promises an alternative alloying strategy for enhancing Na metal interfacial stability in the common EC/PC electrolyte for their future applications.

关键词： EC/PC electrolyte Sodium metal batteries Na/In/C electrode Dendrite-free and smooth morphology Theoretical simulations

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