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Is it possible to develop a cerebellar reserve?

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Neural Regeneration Research 2022年第5期17卷 994-996页

作者： Francesca Gelfo laura Petrosini Department of Human Sciences Guglielmo Marconi UniversityRomeItaly IRCCS Fondazione Santa Lucia RomeItaly

The concept of neural plasticity accounts for the now well clarified brain ability to react to internal and external stimuli by transforming its structure and *** translation of whatever experience in specific electrical signals that run through our neural networks induces a number of plastic changes at both functional and structural levels.

关键词： function. translation clarified

SOME PROPERTIES OF OPERATOR-VALUED FRAMES

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Acta Mathematica Scientia 2016年第2期36卷 469-476页

作者： laura GAVRUTA Pasc GAVRUTA politehnica university of timisoara department of mathematicsVictoriei Square no.2300006 TimisoaraRomania

Operator-valued frames （or g-frames） are generalizations of frames and fusion frames and have been used in packets encoding, quantum computing, theory of coherent states and more. In this article, we give a new formula for operator-valued frames for finite dimensional Hilbert spaces. As an application, we derive in a simple manner a recent result of A. Najati concerning the approximation of g-frames by Parseval ones. We obtain also some results concerning the best approximation of operator-valued frames by its alternate duals, with optimal estimates.

关键词： Frames g-frames

In vitro Metabolomic Approaches to Investigating the Potential Biological Effects of Phenolic Compounds:An Update

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Genomics, Proteomics & Bioinformatics 2017年第4期15卷 236-245页

作者： Ursula Catalan laura Barrubes Rosa Maria Vails Rosa Soila laura Rubio Functional Nutrition Oxidation and Cardiovascular Diseases Group(NFOC-Salut)Technological Center of Nutrition and Health(CTNS)lnstitut d'lnvestigacio Sanitaria Pere Virgili(IISPV)Faculty of Medicine and ttealth SciencesUniversitat Rovira i VirgiliReus 43201Spain Food Technology Department Universitat de Lleida-AGROTECNIO CenterLleida 25198Spain

Dietary phenolic compounds （PCs） have been receiving intercst lor their presumcd roles ill disease prevention. However, there is a lack of studies on the underlying molecular mechanisnls. In this regard, in vitro metabolomic approaches are suitable for the investigation o1 the molecular changes in response to PC exposure. Up to date, the biological effects of PCs have only been cxalnined for PCs from rosemary （Rosmarinus officinalis）, olive oil, and reSVCl-atrol using cell-based mctabolomic approach, although transcriptomic and/or proteomic studies have also been conducted in the same in vi[ro cell experiment in some cases. Our integral analysis of the reviewed studies suggest that PCs may be involved not only in basic cellular processes or macro-and micro-nutrient meta- bolism, but also in specific metabolic pathways that have been thoroughly investigated. These modulated pathways could have a clinical impact on neurodegenerativc diseases, type 2 diabetes, cancer, and cardiovascular diseases. In conclusion, the in vitro metabolomic approaches provide additional information of the molecular mechanisms involved in disease risk reduction of dietary PCs. In order to elucidate the mechanisms of action of PCs, more metabolomic cell-based studies are nccdcd and testing the physiological conjugated forms of PCs in these cell systems could be of special interest.

关键词： Cell-based Metabolomics Phenolic compounds Mechanism of action Disease prevention

Novel Galectin-3 interactions involved in oligodendroglial differentiation make inroads into therapeutic strategies for demyelinating diseases

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Neural Regeneration Research 2021年第2期16卷 289-290页

作者： laura Andrea Pasquini Department of Biological Chemistry School of Pharmacy and BiochemistryInstitute of Biological Chemistry and Physicochemistry(IQUIFIB)University of Buenos Aires and National Research Council(CONICET)Buenos AiresArgentina

Galectins(Gals)constitute a 15-member class ofβ-galactoside-binding lectins which recognize *** lacking specific receptors,Gals form multivalent complexes with cell surface glycoconjugates containing suitable oligosaccharides and thus trigger intracellular signals to regulate cell survival and *** are classified into three groups on the basis of their structural architecture:proto,chimera and tandem types。

关键词： spite complexes strategies

Removal of saxitoxin and anatoxin-a by PAC in the presence and absence of microcystin-LR and/or cyanobacterial cells

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Journal of Environmental Sciences 2023年第6期128卷 161-170页

作者： Justin Rorar laura Davila Garcia Teresa Cutright Department of Civil Engineering The University of AkronOH 44325-3905USA

Cyanobacteria can produce cyanotoxins such as microcystin-LR(MC),saxitoxin(STX),and anatoxin-a(ANTX-a)which are harmful to humans and other *** removal efficiencies of STX and ANTX-a by powdered activated carbon(PAC)was investigated,aswell as when MC-LR and cyanobacteriawere *** conductedwith distilled water and then source water,using the PAC dosages,rapid mix/flocculation mixing intensities and contact times of two drinking water treatment plants in northeast *** pH 8 and 9,STX removal was 47%-81%in distilled water and 46%-79%in source water,whereas it was 0-28%for pH 6 in distilled water and 31%-52%in source *** 1.6μg/L or 20μg/L MC-LR was present with STX,STX removal was increased with PAC simultaneously removing 45%-65%of the 1.6μg/L MC-LR and 25%-95%of the 20μg/L MC-LR depending on the ***-a removal at pH 6 was 29%-37%for distilled water and 80%for source water,whereas it was 10%-26%for pH 8 in distilled water and 28%for pH 9 in source *** presence of cyanobacteria cells decreased ANTX-a removal by at least 18%.When 20μg/L MC-LR was present with ANTX-a in source water,59%-73%ANTX-a and 48%-77%of MCLR was removed at pH 9 depending on the PAC *** general,a higher PAC dose led to higher cyanotoxin *** study also documented that multiple cyanotoxins can be effectively removed by PAC for water at pH’s between 6 and 9.

关键词： pH Cyanotoxins Cyanobacteria PAC Microcystin Saxitoxin Anatoxin-a

What good is the reserve? A translational perspective for the managing of cognitive decline

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Neural Regeneration Research 2019年第7期14卷 1219-1220页

作者： laura Serra Francesca Gelfo Neuroimaging Laboratory IRCCS Fondazione Santa Lucia Department of Clinical and Behavioural Neurology IRCCS Fondazione Santa Lucia Department of Human Sciences Guglielmo Marconi University

The concept of reserve appears in the neurological literature in the 1940s arising from the observation that there is no linear relationship between neurological damage and severity of the clinical ***,this concept sustains that the experiences pursued during life-span enrich the brain by making it more resilient to neuronal ***,in the last three decades the reserve concept has become very popular in the scientific field,mainly associated with the pathophysiological mechanisms underlying the Alzheimer’s Disease(AD)(Serra et al.,2018;Stern et al.,2018).

关键词： reserve appears neurological literature reserve concept

Necrotizing Pneumonia and Conservative Treatment: A Case Report and Review of the Literature

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Open Journal of Respiratory Diseases 2024年第3期14卷 69-76页

作者： Pedro Rogerio Magalhães Braga Eduarda Kipper Beck Carolina de Mello Viera Cecília Gatti Wolff laura Gazal Passos Guilherme Bastos de Mello Luis Felipe Pilar Gomes Giacomo Farias Tramontin Taíse Rosa de Carvalho Department of Internal Medicine Hospital So Lucas da PUCRS Porto Alegre Brazil School of Medicine Pontifcia Universidade Catlica do Rio Grande do Sul Porto Alegre Brazil Department of Radiology Hospital So Lucas da PUCRS Porto Alegre Brazil

We present a case of necrotizing pneumonia in an 87-year-old man without severe respiratory instability. Clinical suspicion arose due to the need for supplementary oxygen and persistent fever during treatment for community-acquired pneumonia. The diagnosis was confirmed by chest computed tomography. Although necrotizing pneumonia typically requires major surgical intervention upon diagnosis, we chose conservative management with antimicrobials and chest drainage alone. The patient experienced significant improvement and resolution of pneumonia with conservative management.

关键词： Respiratory Tract Infections Lung Disease Bacterial Pneumonia

Progesterone for the treatment of central nervous system disorders: the many signaling roads for a single molecule

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Neural Regeneration Research 2020年第10期15卷 1846-1847页

作者： Susana laura González Universidad de Buenos Aires Facultad de Medicina Departamento de Bioquímica Humana Buenos Aires Laboratorio de Nocicepción y Dolor Neuropático Instituto de Biología y Medicina Experimental

Central nervous system(CNS)injuries and neurodegenerative diseases show a broad spectrum of common pathophysiological processes,including oxidative stress,neuroinflammation,excitotoxicity,demyelination and neurotransmission *** the past decades,valuable experimental investigations have helped to clarify the role and timing of these multiple molecular and cellular mechanisms in each of these particular disorders,which usually overlap and critically contribute to long-term ***,up to now,no definite cures or effective disease-modifying therapies are available for any of these *** has led to an active search of novel therapeutic approaches,including the repositioning of existing drugs for new indications,as a valid approach to promptly move candidate molecules to clinical trials.

关键词： injuries disorders drugs

Probabilistic transitions for P systems

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Progress in Natural Science:Materials International 2007年第4期17卷 432-441页

作者： Gabriel Ciobanu laura Cornǎcel "A. I. Cuza" University Faculty of Computer ScienceBlvd. Carol I No. 11700506 IasiRomania Romanian Academy Institute of Computer ScienceBlvd. Carol I No.8700505 IasiRomania

In this paper we use the abstract syntax and the structural operational semantics of the P systems given in [ 1 ], and add probabilities to the rules and to the communication targets. We take into account the number of possible combinations of rules which can be applied in a computation step, as well as the consumption degree of the current resources.

关键词： probabilistic transition P systems.