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Actinomycosis of the appendix mimicking appendiceal tumor:A case report

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World Journal of Gastroenterology 2010年第3期16卷 395-397页

作者： Sang-Yun Lee Hee-jin Kwon jin-Han Cho Jong-Young Oh kyung-jin nam jin-Hwa Lee Seong-Kuk Yoon Myong-jin Kang jin-Sook Jeong Department of Radiology Dong-A University Hospital Department of Pathology Dong-A University Hospital

Actinomycosis is an uncommon chronic infectious disease. Common sites of involvement include the cervicofacial, thoracic and abdominopelvic regions. In abdominopelvic actinomycosis, the ileocecal region, including the appendix, is the most commonly involved site. In some reports, limited appendiceal actinomycosis has revealed a thickened appendiceal wall with peri-appendiceal inflammation as acute appendicitis or perforated appendicitis. We experienced pathologically confirmed intraluminal limited appendiceal actinomycosis without peri-appendiceal infiltration. Here, we report the computed tomography and ultrasound findings.

关键词： Actinomyces Actinomycosis Appendiceal neoplasms Appendicitis

Splenic infarction associated with sorafenib use in a hepatocellular carcinoma patient

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World Journal of Gastroenterology 2011年第2期17卷 267-270页

作者： Sang Ock Kim Sang Young Han Yang Hyun Baek Sung Wook Lee Ji Sun Han Byung Geun Kim jin Han Cho kyung jin nam Department of Gastroenterology and Hepatology Dong-A University HospitalDongdaesin-dong Seo-gu Busan 602-103 South Korea Dong-A University Collegeof Medicine 3-ga Dongdaesing-dong Seo-gu Busan 602-103South Korea Department of Radiology Dong-AUniversity Hospital Dongdaesin-dong Seo-gu Busan 602-103South Korea

Sorafenib,a multitargeted tyrosine kinase inhibitor,has been shown to improve survival in patients with advanced hepatocellular carcinoma(HCC).As the clinical use of sorafenib increases,many adverse effects have been reported,such as hand-foot skin reaction,diarrhea,anorexia,asthenia,alopecia,weight loss,hypertension and arterial ***,there are no prior reports of splenic infarction as an adverse effect of ***,a case of splenic infarction in a patient with HCC who was treated with sorafenib is reported. The patient had no other predisposing factors to explain the splenic infarction except for the administration of *** splenic infarction improved after sorafenib was discontinued;however,the HCC progressed.

关键词： Hepatocellular carcinoma Sorafenib Tyrosine kinase inhibitor Adverse effects Splenic infarction

Efficacy of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma

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World Journal of Gastroenterology 2012年第26期18卷 3426-3434页

作者： Yang Hyun Baek Kyoung Tae Kim Sung Wook Lee jin Sook Jeong Byeong Ho Park kyung jin nam jin Han Cho Young Hoon Kim Young Hoon Roh Hyung Sik Lee Young Min Choi Sang Young Han Department of Internal Medicine Dong-A University College of MedicineBusan 602-103South Korea Department of Pathology Dong-A University College of MedicineBusan 602-103South Korea Department of Radiology Dong-A University College of MedicineBusan 602-103South Korea Department of Surgery Dong-A University College of MedicineBusan 602-103South Korea Department of Radiation Oncology Dong-A University College of MedicineBusan 602-103South Korea

AIM:To investigate the efficacy of hepatic arterial infusion chemotherapy(HAIC) using floxuridine(FUDR) in patients with advanced hepatocellular carcinoma(HCC) confined to the ***:Thirty-four patients who had advanced HCC with unresectability or unsuccessful previous therapy in the absence of extrahepatic metastasis were treated with intra-arterial FUDR chemotherapy at ourhospital between March 2005 and May *** the 34 patients,9 patients were classified as Child class C,and 18 patients had portal vein tumor thrombus(PVTT).One course of chemotherapy consisted of continuous infusion of FUDR(0.3 mg/kg during day 1-14) and dexamethasone(10 mg on day 1,4,7 and 11),and this treatment was repeated every 28 ***:Two patients(5.9%) displayed a complete response,and 12 patients(35.3%) had a partial *** tumor control rate was 61.8%.The median overall survival times were 15.3 mo,12.4 mo and 4.3 mo for the patients who were classified as Child class A,Child class B and Child class C,respectively(P = 0.0392).The progression-free survival was 12.9 mo,7.7 mo and 2.6 mo for the patients who were classified as Child class A,Child class B and Child class C,respectively(P = 0.0443).The cumulative survival differed significantly according to the Child-Pugh classification and the presence of *** addition to hepatic reserve capacity and PVTT,the extent of HCC was an independent factor in determining a poor *** most common adverse reactions to HAIC were mucositis,diarrhea and peptic ulcer disease,but most of these complications were improved by medical treatment and/or a delay of ***:The present study demonstrates that intra-arterial FUDR chemotherapy is a safe and effective treatment for advanced HCC that is recalcitrant to other therapeutic modalities,even in patients with advanced cirrhosis.

关键词： Hepatic arterial infusion chemotherapy Floxuridine Advanced hepatocellular carcinoma Child-Pugh classification Portal vein tumor thrombus

Male metaplastic breast cancer with poor prognosis:A case report

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World Journal of Clinical Cases 2022年第15期10卷 4964-4970页

作者： Hyun Yul Kim Seungju Lee Dong-il Kim Chang Shin Jung Jee Yeon Kim kyung jin nam Ki Seok Choo Youn Joo Jung Department of Surgery Pusan National University Yangsan HospitalPusan National University School of MedicineGyeongnam 50612South Korea Department of Pathology Pusan National University Yangsan HospitalPusan National University School of MedicineGyeongnam 50612South Korea Department of Radiology Pusan National University Yangsan HospitalPusan National University School of MedicineGyeongnam 50612South Korea

BACKGROUND Metaplastic breast cancer(MBC)is a rare subtype of breast *** constitute less than 1%of breast cancer cases and are much rarer in *** are few reports of MBC because of its ***,an aggressive type of cancer,is refractory to common treatment modalities of breast cancer and has a poor *** SUMMARY We report a case of MBC in a 78-year-old *** visited our clinic with a palpable mass on the left breast with no masses in the axillary *** had previously undergone robot-assisted laparoscopic radical prostatectomy for prostate cancer,but there was no family history of *** breast mass was visible on ultrasonography,mammography,and magnetic resonance imaging,and chest computed tomography revealed a lung mass in the posterior basal segment of the right lower *** patient was diagnosed with metaplastic carcinoma on core needle biopsy with lung *** mastectomy with sentinel lymph node biopsy and video-assisted segmentectomy of the right lung was ***,multiple metastases appeared 3 mo after surgery in the brain,chest,and abdomen,and the patient died 5 mo after the initial *** MBC is an aggressive and extremely rare breast cancer *** case reports are needed to determine the optimal treatment.

关键词： Breast neoplasm Male Triple-negative breast cancer Metaplastic breast cancer Adjuvant treatment Case report

Therapeutic efficacy and stent patency of transhepatic portal vein stenting after surgery

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World Journal of Gastroenterology 2016年第44期22卷 9822-9828页

作者： Ung Bae Jeon Chang Won Kim Tae Un Kim Ki Seok Choo Joo Yeon Jang kyung jin nam Chong Woo Chu Je Ho Ryu Department of Radiology Pusan National University Yangsan Hospital Department of Radiology Medical Research Institute Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology Pusan National University Hospital Department of Surgery Pusan National University Yangsan Hospital

AIM To evaluate portal vein(PV) stenosis and stent patency after hepatobiliary and pancreatic surgery, using abdominal computed tomography(CT).METHODS Percutaneous portal venous stenting was attempted in 22 patients with significant PV stenosis(> 50%)-after hepatobiliary or pancreatic surgery- diagnosed by abdominal CT. Stents were placed in various stenotic lesions after percutaneous transhepatic portography. Pressure gradient across the stenotic segment was measured in 14 patients. Stents were placed when the pressure gradient across the stenotic segment was > 5 mm Hg or PV stenosis was > 50%, as observed on transhepatic portography. Patients underwent followup abdominal CT and technical and clinical success, complications, and stent patency were *** Stent placement was successful in 21 patients(technical success rate: 95.5%). Stents were positioned through the main PV and superior mesenteric vein(n = 13), main PV(n = 2), right and main PV(n = 1), left and main PV(n = 4), or main PV and splenic vein(n = 1). Patients showed no complications after stent placement. The time between procedure and final follow-up CT was 41-761 d(mean: 374.5 d). Twenty stents remained patent during the entire follow-up. Stent obstruction-caused by invasion of the PV stent by a recurrent tumor- was observed in 1 patient in a follow-up CT performed after 155 d after the procedure. The cumulative stent patency rate was 95.7%. Small in-stent low-density areas were found in 11(55%) patients; however, during successive follow-up CT, the extent of these areas had *** Percutaneous transhepatic stent placement can be safe and effective in cases of PV stenosis after hepatobiliary and pancreatic surgery. Stents show excellent patency in follow-up abdominal CT, despite development of small in-stent low-density areas.

关键词： Liver Vein Stent Computed tomography Surveillance Efficace

Imidazole linker‐induced covalent triazine framework-ZIF hybrids for confined hollow carbon super‐heterostructures toward a long‐life supercapacitor

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Carbon Energy 2023年第10期5卷 25-39页

作者： Madagonda MVadiyar Ji‐Young Kim Jee‐Hwan Bae kyung‐Wan nam Department of Energy and Materials Engineering Dongguk UniversitySeoulSouth Korea Advanced Analysis&Data Center Korea Institute of Science and Technology(KIST)SeoulSouth Korea Advanced Energy and Electronic Materials Research Center Dongguk UniversitySeoulSouth Korea

Carbon super-heterostructures with high nitrogen contents from the covalent hybrid precursors of covalent triazine frameworks(CTFs)and zeolitic imidazolic frameworks(ZIFs)are scarcely explored because of CTF's ordered structure and toxic superacid that dissolves or destabilizes the metal *** solve this problem,herein,we report a straightforward two-step pathway for the covalent hybridization of disordered CTF(d–CTF)–ZIF composites via preincorporation of an imidazole(IM)linker into ordered CTFs,followed by the imidazole-site-specific covalent growth of *** carbonization of these synthesized d–CTF−IM−ZIF hybrids results in unique hollow carbon super-heterostructures with ultrahigh nitrogen content(>18.6%),high specific surface area(1663m^(2)g^(−1)),and beneficial trace metal(Co/Zn NPs)contents for promoting the redox *** proof of concept,the obtained carbon super-heterostructure(Co–Zn–NC_(SNH)–800)is used as a positive electrode in an asymmetric supercapacitor,demonstrating a remarkable energy density of 61Wh kg^(−1)and extraordinary cyclic stability of 97%retention after 30,000 cycles at the cell *** presynthetic modifications of CTF and their covalent hybridization with ZIF crystals pave the way toward new design strategies for synthesizing functional porous carbon materials for promising energy applications.

关键词： asymmetric supercapacitor defective covalent triazine frameworks hollow carbon superheterostructures linker defect

Effect of Isothermal Annealing on Nano Ti-Carbides Precipitation

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Journal of Iron and Steel Research International 2011年第S1期18卷 287-289页

作者： Cheol-ho Park Woo-jin Kim nam-hyun Kang Hyung-hyup Do kyung-Mox Cho Department of Materials Science and Engineering Pusan National UniversityBusan 609-735Korea Technical Research Laboratories Hyundai steelsDangjinChungnam 343-711Korea

Transmission electron microscopy was used to investigate the effect of isothermal holding temperature and time on the nano Ti-precipitates.A holding temperature was varied systematically from 400℃ to 1200℃.The isothermal holding was continued for 30s,300s and 900s,*** carbides of (Ti,Nb)C were precipitated significantly at 900℃.The size of carbides was approximately 10nm at 30s holding and increased to 20～30nm at 900s *** holding at 1000℃ showed the increased amount of carbides larger than *** 800℃,nano (Ti,Nb)C was not observed at 30s and it was examined at *** size of nano (Ti,Nb)C was smaller than that of 900℃.As the isothermal temperature decreased to 700 ℃,the nano (Ti,Nb)C was only seen at 900s holding and the size of carbides was smaller than *** (Ti,Nb)C was disappeared at isothermal holding below 600℃.The kinetics of nano (Ti,Nb)C precipitation were studied as a function of isothermal holding temperature and time,respectively,using the precipitate growth equations.

关键词： Ti carbide hot rolled steel hole expansion ratio isothermal holding nano precipitates

Lesion localization of global aphasia without hemiparesis by overlapping of the brain magnetic resonance images

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Neural Regeneration Research 2014年第23期9卷 2081-2086页

作者： Woo jin Kim nam-Jong Paik Department of Rehabilitation Medicine Seoul National University Bundang Hospital Department of Physical Medicine and Rehabilitation Haeundae Paik Hospital Inje University of Medicine Department of Rehabilitation Medicine Seoul National University College of Medicine

Global aphasia without hemiparesis is a striking stroke syndrome involving language impairment without the typically manifested contralateral hemiparesis, which is usually seen in patients with global aphasia following large left perisylvian lesions. The objective of this study is to elucidate the specific areas for lesion localization of global aphasia without hemiparesis by retrospectively studying the brain magnetic resonance images of six patients with global aphasia without hemiparesis to define global aphasia without hemiparesis-related stroke lesions before overlapping the images to visualize the most overlapped area. Talairach coordinates for the most overlapped areas were converted to corresponding anatomical regions. Lesions where the images of more than three patients overlapped were considered significant. The overlapped global aphasia without hemiparesis related stroke lesions of six patients revealed that the significantly involved anatomi- cal lesions were as follows： frontal lobe, sub-gyral, sub-lobar, extra-nuclear, corpus callosum, and inferior frontal gyrus, while caudate, claustrum, middle frontal gyrus, limbic lobe, temporal lobe, superior temporal gyrus, uncus, anterior cingulate, parahippocampal, amygdala, and subcallosal gyrus were seen less significantly involved. This study is the first to demonstrate the heterogeneous anatomical involvement in global aphasia without hemiparesis by overlapping of the brain magnetic resonance images.

关键词： nerve regeneration global aphasia without hemiparesis global aphasia stroke hemiparesis brain magnetic resonance imaging neural regeneration

Spatio-temporal variability in sea surface wind stress near and off the east coast of Korea

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Acta Oceanologica Sinica 2005年第1期24卷 107-114页

作者： nam SungHyun KIM Young Ho PARK kyung-Ae KIM Kuh Ocean Laboratory/RIO School of Earth and Environmental Sciences Seoul National University Seoul 151-742 KoreaOcean Laboratory/RIO School of Earth and Environmental Sciences Seoul National University Seoul 151-742 KoreaOcean Laboratory/RIO School of Earth and Environmental Sciences Seoul National University Seoul 151-742 KoreaOcean Laboratory/RIO School of Earth and Environmental Sciences Seoul National University Seoul 151-742 Korea

Sea surface wind stress variabilities near and off the east coast of Korea, are examined using 7 kinds of wind datasets from measurements at 2 coastal (land) stations and 2 ocean buoys,satellite scatterometer (QuikSCAT), and global reanalyzed products (ECMWF,NOGAPS,and NCEP/NCAR). Temporal variabilities are analyzed at 3 frequency bands; synoptic (2-20 d), intra-seasonal (20-90 d),and seasonal (>90 d).Synoptic and intra-seasonal variations are predominant near and off the Donghae City due to the passage of the mesoscale weather system. Seasonal variation is caused by southeastward wind stress during Asian winter monsoon. The sea surface wind stress from reanalyzed *** and KMA-B measurements off the coast show good agreement in the magnitude and direction,which are strongly aligned with the alongshore *** the land-based sites,wind stresses are much weaker by factors of 3-10 due to the mountainous landmass on the east parts of Korea *** first EOF modes(67%-70%) of wind stresses from reanalyzed and QuikSCAT data have similar structures of the strong southeastward wind stress in winter along the coast but show different curl structures at scales less than 200 km due to the orographic *** second EOF modes (23%-25%) show southwestward wind stress in every September along the east coast of the North Korea

关键词： sea surface wind stress spatio-temporal variability monsoon seasonal intra-seasonal synoptic band orographic effect