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Journal of Geographical Sciences 2006年第1期16卷 116-118页

作者： katri makkonen Zhao Xin

The International Workshop on ＂Expanding Transboundary Cooperation for Water and Environment Security in Asia＇s International Rivers＂ was held on December 10-14, 2005, Dali, Yunnan, China. It was organized by Tsinghua University, the World Bank Institute （WBI）, the United Nations University （UNU） and Asian International Rivers Center （AIRC）. A total of over 60 scholars from the USA, Canada, Australia, Finland, Japan, Thailand, Vietnam, Laos, India, Sri Lanka, Iran and China participated in this workshop. The topics include seeking reasonable utilization and sustainable conflict resolutions related to transboundary water resources, and transboundary ecosecurity maintenance; expanding cooperation between Asia and the rest of the world on international river issues, identifying potential opportunities; and possibility of a common research agenda for addressing environment changes in Mekong River Basin.

关键词：亚洲国际河流跨境生态安全合作国际学术研讨会 the world water resources United Nations Mekong River

Modeling the dynamics of innovation ecosystems

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International Journal of Innovation Studies 2023年第2期7卷 142-158页

作者： Jaakko Paasi Henri Wiman Tina Apilo katri Valkokari VTT Technical Research Centre of Finland Ltd. P.O.Box 1000FI-02044VTTFinland

Demand for solving systemic problems has resulted in the need for new forms of ***,the concept of innovation ecosystem has *** are intrinsically more fluid than networks,which set ups the need to understand and orchestrate the internal dynamics of innovation ecosystem in order to have successful innovation *** dynamics of ecosystems,however,is not well *** this paper the dynamics of innovation ecosystems has been studied by applying the methodology of system *** purpose of the study is to support the creation of innovation ecosystems and the orchestration of existing ecosystems so that they could be more *** factors generating dynamics in innovation ecosystems were *** form the elements of the system dynamics model of innovation *** causal loop structure between the model elements indicates how the key factors of dynamics influence the outcome of ecosystem.

关键词： Ecosystem Innovationecosystem Open innovation Systemdynamics Modeling

Antibodies in celiac disease:implications beyond diagnostics

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Cellular & Molecular Immunology 2011年第2期8卷 103-109页

作者： Sergio Caja Markku Maki katri Kaukinen katri Lindfors Pediatric Research Centre University of Tampere and Tampere University HospitalTampereFinland Medical School University of Tampere and Department of Gastroenterology and Alimentary Tract SurgeryTampere University HospitalTampereFinland

Celiac disease is a multisystemic dietary,gluten-induced autoimmune disorder characterized by the presence of transglutaminase(TG)2 serum *** autoantibodies targeting members of the TG family(TG2,TG3 and TG6)are found deposited in small-bowel mucosa and in extraintestinal tissues affected by the *** autoantibodies against other self-antigens also emerge in untreated celiac disease *** villous atrophy and crypt hyperplasia in small-bowel biopsy samples are still the gold standards in diagnostics,celiac disease-specific antibodies are widely used as diagnostic ***-induced small-bowel mucosal T-cell response is the cornerstone in the pathogenesis of the disorder,but humoral immunity may also play a central *** review article is focused on the autoantibodies that occur in the context of celiac *** article summarizes the diagnostic utility of different celiac-related antibodies and discusses their roles in the pathogenesis of the disease.

关键词： antibody celiacdisease diagnostics pathogenesis

Even low-grade inflammation impacts on small intestinal function

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World Journal of Gastroenterology 2010年第9期16卷 1057-1062页

作者： katri Peuhkuri Heikki Vapaatalo Riitta Korpela Institute of Biomedicine University of Helsinki Netnut Nutrition Information Services Company Valio Research Centre PO Box 30FI-00039 HelsinkiFinland

Independent of the cause and location,inflammation-even when minimal-has clear effects on gastrointestinal morphology and *** result in altered digestion,absorption and barrier *** is evidence of reduced villus height and crypt depth,increased permeability,as well as altered sugar and peptide absorption in the small intestine after induction of inflammation in experimental models,which is supported by some clinical *** of inflammatory factors which may promote the process of gastrointestinal dysfunction as well as clinical research to verify experimental observations of inflammatory modulation of gastrointestinal function are ***,nutritional strategies to support functional restitution are needed.

关键词： Small intestine Digestion Absorption Motility Permeability Low-grade inflammation Cytokines

Endomysial antibodies predict celiac disease irrespective of the titers or clinical presentation

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World Journal of Gastroenterology 2012年第20期18卷 2511-2516页

作者： Kalle Kurppa Tiia Rsnen Pekka Collin Sari Iltanen Heini Huhtala Merja Ashorn Pivi Saavalainen katri Haimila Jukka Partanen Markku Mki katri Kaukinen Pediatric Research Centre University of Tampere and Tampere University HospitalFin-33014Tampere Finland Department of Gastroenterology and Alimentary Tract Surgery Tampere University Hospital and School of MedicineUniversity of TampereFin-33014 TampereFinland Tampere School of Public Health University of TampereFin-33014TampereFinland Department of Medical Genetics and Research Program for Molecular Medicine University of Helsinki Fin-00014HelsinkiFinland Research and Development Finnish Red Cross Blood ServiceFin-00310HelsinkiFinland

AIM:To investigate the association between serum antibody levels and a subsequent celiac disease diag-nosis in a large series of children and adults. METHODS:Besides subjects with classical gastrointestinal presentation of celiac disease,the study cohort included a substantial number of individuals with extraintestinal symptoms and those found by screening in at-risk *** 405 patients underwent clinical,serological and histological *** collection of data,the antibody values were further graded as low[endomysial(EmA)1:5-200,transglutaminase 2 antibodies(TG2-ab)5.0-30.0 U/L]and high (EmA 1:≥500,TG2-ab≥30.0 U/L),and the serological results were compared with the small intestinal mucosal histology and clinical presentation. RESULTS:In total,79%of the subjects with low and 94%of those with high serum EmA titers showed small-bowel mucosal villous ***, 96%of the 47 EmA positive subjects who had normal mucosal villi and remained on follow-up either subsequently developed mucosal atrophy while on a glutencontaining diet,or responded positively to a glutenfree diet. CONCLUSION:Irrespective of the initial serum titers or clinical presentation,EmA positivity as such is a very strong predictor of a subsequent celiac disease diagnosis.

关键词：疾病诊断临床表现抗体水平腹腔滴度预测内膜转谷氨酰胺酶

Impact of nurse staffing on reducing infant, neonatal and perinatal mortality rates: Evidence from panel data analysis in 35 OECD countries

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International Journal of Nursing Sciences 2020年第2期7卷 161-169页

作者： Arshia Amiri katri Vehviläinen-Julkunen Tytti Solankallio-Vahteri Sirpa Tuomi School of Health and Social Studies JAMK University of Applied SciencesJyväskyläFinland Department of Nursing Science University of Eastern FinlandKuopioFinland

Objectives:To investigate the magnitude of effect nurse staffing had on decreasing the newborn mortality rates in member countries of Organisation for Economic Co-operation and Development(OECD).Methods:The statistical technique of panel data analysis was applied to explore the possibility of association between the number of nurses'density per 1,000 population and infant,neonatal and perinatal mortality rates(IMR,NMR and PMR)per 1000 *** observations of 35 OECD countries were collected over the period of 2000 through ***:There were significant associations between nurse staffing and IMR,NMR and PMR i.e.a 1%increase in nurse-staffing level reduced IMR,NMR and PMR by 0.98%,0.97%and 0.96%,***,the role of nursing-related services in declining the average of newborn mortality rates were investigated at the highest level in Slovenia(-5.50),Sweden(-3.34),Iceland(-2.51),Czech Republic(-1.86),Japan(-1.64)and Finland(-1.64).Moreover,if the current relationship between nursestaffing level and newborn mortality rates are disturbed with nursing shortage(*** Slovak Republic and Israel),then it takes about 17 years for the mortality rates to reduce and restore back to the previous ***:A higher proportion of nurses'density per 1,000 population is associated with lower newborn mortality *** addition,the nursing-related services of Slovenia,Sweden,Iceland,Czech Republic,Japan and Finland with the highest impact on improving the health level of newborns would be good patterns for other developed countries in maternity and child health care.

关键词： Health manpower Infant mortality Nursing staff Organisation for Economic Co-operation and Development Perinatal mortality

Immunogenetic characteristics of patients with autoimmune gastritis

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World Journal of Gastroenterology 2010年第3期16卷 354-358页

作者： Aino Mirjam Oksanen katri Eerika Haimila Hilpi Iris Kaarina Rautelin Jukka Antero Partanen Herttoniemi Hospital Health Centre Finnish Red Cross Blood Service Clinical Laboratory Department of Bacteriology and Immunology Haartman InstituteUniversity of Helsinki HUSLAB Helsinki University Central Hospital Department of Medical Sciences University and University Hospital of Uppsala Finnish Red Cross Blood Service Research and Development

AIM:To explore whether predisposition to autoimmune gastritis (AIG) is found in human leukocyte antigen (HLA), cytokine or killer cell immunoglobulin-like receptor (KIR) gene ***: Twelve Finnish patients with autoimmunetype severe atrophy of the gastric corpus were included. The patients' serum was analyzed for pepsinogen-interleukin (IL)-1 gene cluster, IL-2, IL-4, IL-6, IL-10, IL-12, interferon γ, transforming growth factor β, and tumor necrosis factor α. Variation in KIR genes was also explored. The results were compared with prevalence of the polymorphisms in Finnish or European ***: All patients had pepsinogen-CONCLUSION: As explored with modern DNA-based methods, HLA-DRB1*04 and DQB1*03 alleles, but not HLA-B8-DRB1*03, may predispose to AIG.

关键词： Atrophic gastritis Autoimmune diseases Cytokines Genetic polymorphisms Human leukocyte antigens Killer cell immunoglobulin-like receptor

Visual Literacy From the Perspective of the VTS Method

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Journal of Literature and Art Studies 2017年第8期7卷 1071-1082页

作者： katri-Helena Rautiainen Aija Jappinen University of Jyvaskyla Jyvaskyla Finland

Associations between rehabilitants’ functional limitations and conclusions made by a multidisciplinary team during vocational rehabilitation evaluation: Turku ICF Study

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Open Journal of Therapy and Rehabilitation 2013年第2期1卷 36-39页

作者： Mikhail Saltychev Aila Kinnunen katri Laimi Department of Brain Trauma and Rehabilitation Turku University Hospital and University of Turku Turku Finland Department of Physical and Rehabilitation Medicine Turku University Hospital and University of Turku Turku Finland Department of Physical and Rehabilitation Medicine Turku University Hospital and University of Turku Turku Finland

Purpose: To investigate associations between functional limitations experienced by rehabilitants and multidisciplinary team’s recommendations during vocational rehabilitation evaluation. Methods: The descriptions of functional limitations were retrospectively identified for 32 patients with chronic musculoskeletal disorders. Vocational rehabilitation evaluation was conducted by a multidisciplinary team in an outpatient clinic of a university hospital. The descriptions were converted to ICF second-level categories. Square contingency coefficient Phi (φ) was calculated to describe the associations between ICF-categories appearing ≥10 times in the study sample and the recommendations given by a professional team. Results: In the study sample, 84 different ICF second-level categories were identified (average 18 codes/subject, range 9 - 25). Of them, 18 categories were observed for at least in 10 rehabilitants. Three statistically significant correlations were observed between these 18 categories and recommendations given by a rehabilitation team. Of them, positive association of moderate strength was found between joint mobility and muscle power functions and recommendation for retirement. Difficulties in walking showed weak negative correlation with recommendation for vocational rehabilitation. Conclusions: During vocational rehabilitation evaluation, the final recommendations given by rehabilitation professionals were only weakly correlated with functional limitations experienced by rehabilitants.

关键词： Occupational Rehabilitation Rehabilitation Assessment Work Ability Work Capacity Correlation

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对非药物方法减轻儿童术后疼痛的调查研究

中华护理杂志 2004年第3期39卷 161-164页

作者：何红姑姜小鹰 katri Vehvilinen-Julkunen Anna-MaijaPietil 福建医科大学护理学院 350004 Department of Nursing Science

采用芬兰TarjaP lkki博士设计的问卷对福建省 5所省级医院 178名护士进行调查 ,了解护士使用非药物方法减轻学龄儿童术后疼痛情况 ,探讨减轻儿童术后疼痛的最佳护理方法。结果提示护士常用的方法有提供术前准备知识、安慰、创造舒适环... 详细信息

采用芬兰TarjaP lkki博士设计的问卷对福建省 5所省级医院 178名护士进行调查 ,了解护士使用非药物方法减轻学龄儿童术后疼痛情况 ,探讨减轻儿童术后疼痛的最佳护理方法。结果提示护士常用的方法有提供术前准备知识、安慰、创造舒适环境、转移注意力和改变体位。护士的年龄、受教育程度、职称、护理经验、有无子女、有无陪伴子女住院经历以及所在医院和科室注重减轻儿童术后疼痛护理的程度 ,均与某些非药物方法的使用存在显著相关。因此 ,应加强护士对使用非药物方法减轻儿童术后疼痛重要性和必要性的认识。

关键词：非药物方法术后疼痛学龄儿童疼痛护理方法