Even low-grade inflammation impacts on small intestinal function

作     者：Katri Peuhkuri Heikki Vapaatalo Riitta Korpela 

作者机构：Institute of BiomedicineUniversity of Helsinki Netnut Nutrition Information Services Company Valio Research CentrePO Box 30FI-00039 HelsinkiFinland 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2010年第16卷第9期

页      面：1057-1062页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Small intestine Digestion Absorption Motility Permeability Low-grade inflammation Cytokines 

摘      要：Independent of the cause and location,inflammation-even when minimal-has clear effects on gastrointestinal morphology and *** result in altered digestion,absorption and barrier *** is evidence of reduced villus height and crypt depth,increased permeability,as well as altered sugar and peptide absorption in the small intestine after induction of inflammation in experimental models,which is supported by some clinical *** of inflammatory factors which may promote the process of gastrointestinal dysfunction as well as clinical research to verify experimental observations of inflammatory modulation of gastrointestinal function are ***,nutritional strategies to support functional restitution are needed.