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The 5-year functional outcomes after radical prostatectomy： a real-life experience in Korea

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Asian Journal of Andrology 2010年第6期12卷 835-840页

作者： Sung Kyu Hong Seung Hwan Doo Dae Sung Kim Won Ki Lee Hong Zoo park Ji Hyun park Seong jin Jeong Cheol Yong Yoon Seok-soo Byun Sang Eun Lee Department of Urology Seoul National University Bundang Hospital Seongnam Kyunggi-do 463-707 Korea

We investigated the functional outcomes regarding erectile function and urinary continence up to 5 years following radical prostatectomy （RP） in a cohort of Korean men. We retrospectively analyzed the clinicopathologic data of 85 Korean men who received open uni- or bilateral nerve-sparing RP for clinically localized prostate cancer and were followed up for at least 5 years postoperatively. From medical records, patients＇ status regarding urinary and erectile function at baseline and postoperative followups after RP was assessed. At 24 and 60 months after RP, proportions of subjects continent （no pads used） were 89.4% and 97.6%, respectively （P = 0.007）. Excluding subjects （n = 24） who preoperatively reported having severe erectile dysfunction or lacked relevant informations, proportions of subjects capable of having vaginal intercourse regardless of erectile aid usage were 47.5% and 37.7% at 24 and 60 months from RP, respectively （P = 0.022）. Patient＇s age at surgery （P = 0.047） and salvage radiation therapy （P = 0.026） were observed to be significant predictors of having erections sufficient for intercourse at 60 months from RP in multivariate analysis. Our results showed that while patients＇ postoperative status regarding urinary continence at 2 years from RP is generally maintained or improved at 5 year point, erectile function was observed to significantly declined from 2 years to 5 years following RP. Such decline in erectile function following RP may be more significant among men who were relatively older at surgery or those who received salvage therapy during postoperative follow-ups.

关键词： impotence prostatectomy prostatic neoplasm urinary incontinence

Formation behavior of anodic TiO_2 nanotubes in fluoride containing electrolytes

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中国有色金属学会会刊：英文版 2009年第4期19卷 842-845页

作者： Byung-Gwan LEE jin-Wook CHOI Seong-Eun LEE Yong-soo JEONG Han-Jun OH Choong-soo CHI School of Advanced Materials Engineering Kookmin University Korea Institute of Materials Science Department of Materials Science Han seo University

TiO2 nanotube layers can be formed with titanium in the electrolytes containing fluoride by electrochemical *** role of fluoride ion,the crystallinity of the anodic oxide,and the chemical state were *** results show the anodic film is composed of oxide and a little amount of *** presence of F- ions leads to chemical dissolution of Ti oxide layer and prevents hydroxide ***,chemical dissolution rate increases with increasing the fluoride content in the range of 0-2%(in mass fraction) because F- ions in electrolyte attack the interface and allow the ions of the electrolyte to easily penetrate into the *** as-anodized TiO2 nanotubes exhibit an amorphous *** treated nanotubes are composed of mixtures of the anatase and rutile phases.

关键词： TiO2纳米管阳极氧化处理氟离子电解质行为二氧化钛化学溶解电化学方法

Variability of the Dokdo Abyssal Current observed in the Ulleung Interplain Gap of the East/Japan Sea

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Acta Oceanologica Sinica 2013年第1期32卷 12-23页

作者： KIM Yun-Bae CHANG Kyung-Il park Jae-Hun park Jong jin East Sea Research Institute Korea Institute of Ocean Science and Technology Research Institute of Oceanography School of Earth and Environmental Sciences Seoul National University Ocean Science Research Department Korea Institute of Ocean Science and Technology Department of Oceanography Kyungpook National University

Subinertial fluctuation of a strong northward deep current, which is referred to the Dokdo Abyssal Current （DAC） by Chang et al. （2009）, is investigated from current records for about 16.5 and 8.0 months in the Ulle- ung Interplain Gap of the East/lapan Sea. The current below 300 m is bottom-intensified and has nearly depth-independent flow. Near bottom, the spectral peaks of the current were found near 10, 20, and 60 d. The DAC variability near 10 d and 20 d is reasonably consistent with the linear theory of topographic Rossby waves （TRWs） in the following aspects：（1） The motion is columnar and bottom-intensified; （2） the theo- retical cutoff frequency is similar to the observation; （3） The observation-based angles of the wavenumber vector are in good agreement with the theoretical ones. The wavelengths of the TRWs with periods of near 10 d and 20 d near Dokdo are significantly shorter than those with similar timescales in the open oceans （100-250 km）. It is primarily due to the weak stratification below 300 m in the East Sea. The deep cur- rent fluctuations with periods of near 10 d and 20 d were accompanied by warm events in the upper layer resulting from eddying processes and/or meandering of the Tsushima Warm Current.

关键词： East/Iapan Sea Ulleung Interplain Gap Deep currents Topographic Ressby waves

Cecal duplication cyst in an infant presenting as shock:A case report

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World Journal of Clinical Cases 2023年第28期11卷 6931-6937页

作者： Seung Mo Kim Sun Hyang Lee Ga Young park Sung Shin Kim Cheol Gu Lee soo Ji jin Department of Pediatrics Soonchunhyang University Bucheon HospitalSoochunhyang University College of MedicineBucheon 14584Gyeonggi-doSouth Korea Department of General Surgery Soonchunhyang University Bucheon HospitalSoonchunhyang University College of MedicineBucheon 14584GyeongGi-DoSouth Korea Department of Pathology Soonchunhyang University Bucheon HospitalSoonchunhyang University College of MedicineBucheon 14584GyeongGi-DoSouth Korea

BACKGROUND Although intestinal obstruction is one of the most common surgical emergencies in an infant,it is difficult to diagnose neonatal enteric duplication cysts(EDC)preoperatively owing to their rarity as a cause of intestinal *** describe a case report of a neonatal EDC presenting intestinal obstruction and *** SUMMARY A 32-d-old male infant with a prenatal sonographic finding of bladder distension was admitted to our hospital for a severely distended abdomen,fever,and *** first diagnostic hypothesis was septic shock and intestinal *** patient’s symptoms worsened;following an emergency surgical exploratory laparotomy and histopathological findings,the final diagnosis of cecal duplication cyst was *** patient’s postoperative course was uneventful,and on the fifth postoperative day,oral feeding *** days later,the patient was discharged from the *** Although EDC located in the cecum is exceptional,it should be considered when evaluating suspected intestinal obstruction and shock.

关键词： Duplication cyst Cecum Intestinal obstruction Infant Shock Case report

Electrolyte changes after bowel preparation for colonoscopy:A randomized controlled multicenter trial

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World Journal of Gastroenterology 2015年第10期21卷 3041-3048页

作者： Kyong Joo Lee Hong Jun park Hyun-soo Kim Kwang Ho Baik Yeon soo Kim Sung Chul park Hyun Il Seo Division of Gastroenterology and Hepatology Department of Internal Medicine Yonsei University Wonju College of Medicine Department of Internal Medicine Hallym University Chuncheon Sacred Heart Hospital Department of Internal Medicine Kangwon National University Hospital Department of Internal Medicine Ulsan Medical University Gangneung Asan Hospital

AIM:To investigate the electrolyte changes between 2-L polyethylene glycol with ascorbic acid 20 g(PEGAsc) and 4-L PEG ***:From August 2012 to February 2013,a total of 226 patients were enrolled at four tertiary *** patients were randomly allocated to a PEG-Asc group or a 4-L *** colonoscopy,patients completed a questionnaire to assess bowel preparation-related symptoms,satisfaction,and *** assessed the bowel preparation using the Boston Bowel Preparation Scale(BBPS).In addition,blood tests,including serum electrolytes,serum osmolarity,and urine osmolarity were evaluated both before and after the ***:A total of 226 patients were *** scores were similar and the adequate bowel preparation rate(BBPS≥6)was not different between the two groups(PEG-Asc vs 4-L PEG,73.2%vs 76.3%,P=0.760).Bowel preparation-related symptoms also were not different between the two *** taste of PEG-Asc was better(41.1%vs 16.7%,P<0.001),and the willingness to undergo repeated bowel preparation was higher in the PEG-Asc group(73.2%vs 59.3%,P=0.027)than in 4-L *** were no significant changes in serum electrolytes in either ***:In this multicenter trial,bowel preparation with PEG-Asc was better than 4-L PEG in terms of patient satisfaction,with similar degrees of bowel preparation and electrolyte changes.

关键词： Colonoscopy Bowel preparation Ascorbic acid Polyet

Scratch formation and its mechanism in chemical mechanical planarization (CMP)

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Friction 2013年第4期1卷 279-305页

作者： Tae-Young KWON Manivannan RAMACHANDRAN jin-Goo park Department of Materials Engineering Hanyang UniversityAnsan 426-791Korea

Chemical mechanical planarization(CMP)has become one of the most critical processes in semiconductor device fabrication to achieve global *** achieve an efficient global planarization for device node dimensions of less than 32 nm,a comprehensive understanding of the physical,chemical,and tribo-mechanical/chemical action at the interface between the pad and wafer in the presence of a slurry medium is *** the CMP process,some issues such as film delamination,scratching,dishing,erosion,and corrosion can generate defects which can adversely affect the yield and *** this article,an overview of material removal mechanism of CMP process,investigation of the scratch formation behavior based on polishing process conditions and consumables,scratch formation mechanism and the scratch inspection tools were extensively *** advantages of adopting the filtration unit and the jet spraying of water to reduce the scratch formation have been *** current research trends in the scratch formation,based on modeling perspective were also discussed.

关键词： Chemical mechanical planarization(CMP) defects,scratch post-CMP cleaning defect source

Fruit quality,anthocyanin and total phenolic contents,and antioxidant activities of 45 blueberry cultivars grown in Suwon,Korea

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第9期14卷 793-799页

作者： jin Gook KIM Hong Lim KIM Su jin KIM Kyo-Sun park Department of Horticulture College of Agriculture and Life SciencesGyeongsang National University Institute of Agriculture and Life Sciences Gyeongsang National University Namhae Sub-Station National Institute of Horticultural and Herbal Science Fruit Research Division National Institute of Horticultural and Herbal Science

Blueberry fruits from 45 commercial cultivars (39 northern highbush and 6 half highbush blueberry) grown in Suwon,Korea were analyzed for fruit size,soluble solids content,titratable acidity,total anthocyanin content,total phenolic content,and antioxidant *** characteristics varied widely among the 45 blueberry *** weight ranged from 0.9 to 3.6 g,soluble solids content from 8.3 to 14.3 °Brix,and titratable acidity from 0.8% to 3.6%.Antioxidant activity ranged from 0.7 to 2.1 mg of quercetin equivalents per gram of fresh berries in different blueberry *** the 45 blueberry cultivars,high amounts of anthocyanins and polyphenols,and high antioxidant activity were observed in 'Elliott','Rubel','Rancocas',and 'Friendship'.

关键词： Northern highbush blueberry Half highbush blueberry Functional food Fruit quality

Comparison of Antioxidant Activities in Black Soybean Preparations Fermented with Various Microorganisms

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Agricultural Sciences in China 2010年第7期9卷 1065-1071页

作者： QIN Yao jin Xiao-nan park Heui Dong Department of Food Science and Technology Kyungpook National University Daegu 702-701 Korea Applied Plant Stress Biology Lab/Divison of Biotechnology/College of Life Sciences and Biotechnology Korea University Seoul 136-713 Korea

Black soybeans [Glycine max（L.） Merrill] were fermented with various GRAS（generally recognized as safe） microorganisms,including Aspergillus sp.,Bacillus *** yeast（Issatchenkia orientalis） at 30°C for 3 *** antioxidant contents,including total phenolics and total flavonoids,and the antioxidant activities of 1,1-diphenyl-2-picrylhydrazine（DPPH）,ferric reducing antioxidant power（FRAP） and *** were analyzed in preparations of fermented black *** cultures proved to yield significant levels of antioxidants compared with non-fermented cultures（P 〈 0.05）.Fermented black soybean preparations possessed antioxidant activities could be attributed to the total phenolics and flavonoids present.

关键词： antioxidant activity black soybean microorganisms fermentation

Mobilization of monocytic myeloid-derived suppressor cells is regulated by PTH1R activation in bone marrow stromal cells

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Bone Research 2023年第2期11卷 354-367页

作者： Eun Jung Lee Kyoung jin Lee Seungpil Jung Kyong Hwa park Serk In park Department of Biochemistry and Molecular Biology Korea University College of MedicineSeoulRepublic of Korea The BK21 Graduate Program Department of Biomedical SciencesKorea University College of MedicineSeoulRepublic of Korea Division of Breast and Endocrine Surgery Department of SurgeryKorea University Anam HospitalSeoulRepublic of Korea Division of Oncology and Hematology Department of Internal MedicineKorea University Anam HospitalSeoulRepublic of Korea Vanderbilt Center for Bone Biology Vanderbilt University School of MedicineNashvilleTNUSA

Myeloid-derived suppressor cells(MDSCs)are bone marrow(BM)-derived immunosuppressive cells in the tumor microenvironment,but the mechanism of MDSC mobilization from the BM remains *** investigated how BM stromal cell activation by PTH1R contributes to MDSC ***1R activation by parathyroid hormone(PTH)or PTH-related peptide(PTHrP),a tumor-derived counterpart,mobilized monocytic(M-)MDSCs from murine BM without increasing immunosuppressive *** vitro cell-binding assays demonstrated thatα4β1 integrin and vascular cell adhesion molecule(VCAM)-1,expressed on M-MDSCs and osteoblasts,respectively,are key to M-MDSC binding to *** PTH1R activation,osteoblasts express VEGF-A and IL6,leading to Src family kinase phosphorylation in *** inhibitors suppressed PTHrP-induced MDSC mobilization,and Src activation in M-MDSCs upregulated two proteases,ADAM-17 and MMP7,leading to VCAM1 shedding and subsequent disruption of M-MDSC tethering to ***,our data provide the molecular mechanism of M-MDSC mobilization in the bones of tumor hosts.

关键词： MMP7 suppressor regulated