The 5-year functional outcomes after radical prostatectomy： a real-life experience in Korea
The 5-year functional outcomes after radical prostatectomy： a real-life experience in Korea作者机构：Department of Urology Seoul National University Bundang Hospital Seongnam Kyunggi-do 463-707 Korea
出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)
年 卷 期：2010年第12卷第6期
页 面：835-840页
核心收录：
学科分类：13[艺术学] 07[理学] 08[工学] 09[农学] 071007[理学-遗传学] 090102[农学-作物遗传育种] 1305[艺术学-设计学（可授艺术学、工学学位）] 0710[理学-生物学] 080203[工学-机械设计及理论] 081304[工学-建筑技术科学] 0802[工学-机械工程] 0813[工学-建筑学] 0901[农学-作物学] 0836[工学-生物工程] 080201[工学-机械制造及其自动化]
主 题：impotence prostatectomy prostatic neoplasm urinary incontinence
摘 要：We investigated the functional outcomes regarding erectile function and urinary continence up to 5 years following radical prostatectomy （RP） in a cohort of Korean men. We retrospectively analyzed the clinicopathologic data of 85 Korean men who received open uni- or bilateral nerve-sparing RP for clinically localized prostate cancer and were followed up for at least 5 years postoperatively. From medical records, patients＇ status regarding urinary and erectile function at baseline and postoperative followups after RP was assessed. At 24 and 60 months after RP, proportions of subjects continent （no pads used） were 89.4% and 97.6%, respectively （P = 0.007）. Excluding subjects （n = 24） who preoperatively reported having severe erectile dysfunction or lacked relevant informations, proportions of subjects capable of having vaginal intercourse regardless of erectile aid usage were 47.5% and 37.7% at 24 and 60 months from RP, respectively （P = 0.022）. Patient＇s age at surgery （P = 0.047） and salvage radiation therapy （P = 0.026） were observed to be significant predictors of having erections sufficient for intercourse at 60 months from RP in multivariate analysis. Our results showed that while patients＇ postoperative status regarding urinary continence at 2 years from RP is generally maintained or improved at 5 year point, erectile function was observed to significantly declined from 2 years to 5 years following RP. Such decline in erectile function following RP may be more significant among men who were relatively older at surgery or those who received salvage therapy during postoperative follow-ups.
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