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Ligand-binding properties of three odorant-binding proteins of the diamondback moth Plutella xylostella

Journal of Integrative Agriculture 2016年第3期15卷 580-590页

作者： zhu Jiao Paolo Pelosi LIU Yang LIN Ke-jian YUAN Hai-bin WANG Gui-rong College of Agriculture Jilin Agricutural University State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection Chinese Academy of Agricultural Sciences

Strategies for insect population control are currently targeting chemical communication at the molecular level. The diamondback moth Plutella xylostella represents one of the most serious pests in agriculture, however detailed information on the proteins mediating olfaction in this species is still poor. This species is endowed with a repertoire of a large number of olfactory receptors and odorant binding proteins（OBPs）. As a contribution to map the specificities of these chemical sensors in the moth and eventually unrave l the complexity of chemodetection, we have measured the affinities of three selected OBPs to a series of potential odorants. Three proteins are highly divergent in their amino acid sequences and show markedly different expression profiles. In fact, PxylOBP3 is exclusively expressed in the antennae of both sexes, PxylOBP9 is male specific and present only in antennae and reproductive organs, while PxylOBP19, an unusual OBP with nine cysteines, is ubiquitously present in all the organs examined. Such expression pattern suggests that the last two proteins may be involved in non-chemosensory functions. Despite such differences, the three OBPs exhibit similar binding spectra, together with high selectivity. Among the 26 natural compounds tested, only two proved to be good ligands, retinol and coniferyl aldehyde. This second compound is particularly interesting being part of the chemical pathway leading to regeneration of lignin, one of the defense strategies of the plant against insect attack, and might find applications as a repellent for P. xylostella and other pests.

关键词： odorant-binding protein Plutella xylostella ligand-binding tryptophan quenchin molecular docking

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The Classification of 2 and 3 Torsion Free Polyhedra

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Acta Mathematica Sinica,English Series 2015年第11期31卷 1659-1682页

作者： jian Zhong PAN Zhong jian zhu Academy of Mathematics and Systems Science Chinese Academy of Sciences

We classify the stable homotopy types of （n- 1）-connected, （n ＋ k）-dimensional polyhedra with 2 and 3-torsion free homologies for k 〈 6. The technique used is matrix problem （bimodule categories） which is give... 详细信息

关键词： Homotopy indecomposable matrix problem

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A Combinatorial Auction-Based Collaborative Cloud Services Platform

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Tsinghua Science and Technology 2015年第1期20卷 50-61页

作者： Xiaowei Zhang bin Li Junwu zhu School of Information Engineering Yangzhou University State Key Laboratory for Novel Software Technology Nanjing University

In this paper, we present a novel, dynamic collaboration cloud platform in which a Combinatorial Auction（CA）-based market model enables the platform to run effectively. The platform can facilitate expense reduction and improve the scalability of the cloud, which is divided into three layers： The user-layer receives requests from end-users, the auction-layer matches the requests with the cloud services provided by the Cloud Service Provider（CSP）, and the CSP-layer forms a coalition to improve serving ability to satisfy complex requirements of *** fact, the aim of the coalition formation is to find suitable partners for a particular CSP. However, identifying a suitable combination of partners to form the coalition is an NP-hard problem. Hence, we propose approximation algorithms for the coalition formation. The Breadth Traversal Algorithm（BTA） and Revised Ant Colony Algorithm（RACA） are proposed to form a coalition when bidding for a single cloud service in the auction. The experimental results show that RACA outperforms the BTA in bid price. Other experiments were conducted to evaluate the impact of the communication cost on coalition formation and to assess the impact of iteration times for the optimal bidding price. In addition, the performance of the market model was compared to the existing CA-based model in terms of economic efficiency.

关键词： cloud computing coalition formation combinatorial auction ant colony algorithm communication cost

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Wnt pathway antagonists and angiogenesis

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Protein & Cell 2010年第10期1卷 898-906页

作者： bin Zhang jian-xing Ma Department of Physiology Department of MedicineThe University of Oklahoma Health Sciences CenterOklahoma CityOk 73104USA

Dysregulation of the Wnt pathway has been extensively studied in multiple diseases,including some angiogenic *** signaling activation is a major stimulator in pathological angiogenesis and thus,Wnt antagonists are believed to have therapeutic potential for neovascular ***,some Wnt antagonists have been identified directly from the anti-angiogenic factor *** review summarizes the recent progress toward understanding of the roles of Wnt pathway antagonists in angiogenic regulation and their mechanism of action,and exploring their therapeutic potential.

关键词： sFRPs Dkk WIF-1 endostatin SERPINA3K curcumin

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Tunable Emission and Energy Transfer of the Novel KY_(1-x)(MoO_(4))_(2-y)(WO_(4))y:xLn^(3+)(Ln^(3+)=Dy^(3+),Eu^(3+),and Tm^(3+))Single-phase White Luminescence Phosphor for White LEDs

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Journal of Wuhan University of Technology(Materials Science) 2023年第6期38卷 1278-1286页

作者： zhu Hai HE bin HUANG Weigang Department of Oncology The Third People's Hospital of ChengduAfiliated Hospital of Southwest Jiaotong University&The Second Affiliated Hospital of ChengduChongqing Medical UniversityChengdu 610031China Medical Research Center The Third People's Hospital of ChengduAfiliated Hospital of Southwest Jiaotong University&The Second Afiliated Hospital of ChengduChongqing Medical UniversityChengdu 610031China National Engineering Research Center for Biomaterials College of Biomedical MaterialsSichuan UniversityChengdu 610064China College of Materials Science and Engineering Sichuan UniversityChengd 610064China

The phosphors of KY_(1-x)(MoO_(4))_(2-y)(WO_(4))y:xLn^(3+)(Ln^(3+)=Tm^(3+),Dy^(3+),Eu^(3+))were synthesized by using a sol-gel ***,the crystal structure,luminescence properties,energy transfer,and white emission of the prepared materials were *** molar ratio of the anion group on the photoluminescence(PL)emission and excitation intensity were investigated,revealing that the optimum intensity could be obtained by using=3:*** optimal Dy^(3+) doping concentration of KY(MoO_(4))1.5(WO4)0.5was *** addition,the color-tunable emissions of Dy^(3+)/Eu^(3+)-codoped KY(MoO_(4))1.5(WO4)0.5phosphors were observed because of the effective energy transfer(ET)from Dy^(3+)to Eu^(3+)***,by doping appropriate concentrations of Tm^(3+),Dy^(3+),and Eu^(3+)and different concentrations of(WO_(4))^(2-),white light emitting phosphors KY_(0.92)(WO_(4))2:0.01Tm^(3+),0.06Dy^(3+),0.01Eu^(3+)with excellent color-rending properties were *** chromaticity coordinate was calculated as(x=0.3238,y=0.3173),closing to the artificial daylight(D65,x=0.313,y=0.329)illuminant,and which indicates the potential application of near ultraviolet White light-emitting diodes(WLEDs).

关键词： rare earth phosphors white LEDs energy transfer sol-gel method

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Strength and ductility synergy of Nb-alloyed Ni_(0.6)CoFe_(1.4) alloys

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International Journal of Minerals,Metallurgy and Materials 2023年第4期30卷 707-714页

作者： jian Wu Heguo zhu Zonghan Xie College of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing 210094China School of Mechanical Engineering University of AdelaideSA 5005Australia

Designing strong, yet ductile, and body-centered cubic(BCC) medium-entropy alloys(MEAs) remains to be a challenge *** this study, the strength–ductility trade-off of Ni_(0.6)CoFe_(1.4)MEAs was tackled via introducing a BCC + face-centered cubic(FCC) dual-phase microstructure. Ni_(0.6)CoFe_(1.4)Nbx(x = 0, 0.05, 0.08, 0.10, and 0.15, in molar ratio) MEAs were prepared using vacuum induction melting. Results show that the new alloy is composed of BCC plus FCC dual phases featuring a network-like structure, and the BCC phase is the main phase in this alloy system. Moreover, the Nb0.10 MEA shows high strength and respectable tensile ductility, representing the best combination of the strength and fracture elongation among the alloys studied here. The remarkable strength of the Nb0.10 MEA is attributed to the combined effect of the solid solution strengthening, the precipitation hardening effect and the interface strengthening effect.

关键词： medium-entropy alloys alloying microstructure mechanical properties strengthening

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An improved bound on accelerated light dark matter

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 105-118页

作者： Liangliang Su Lei Wu bin zhu Department of Physics and Institute of Theoretical Physics Nanjing Normal UniversityNanjing 210023China School of Physics Yantai UniversityYantai 264005China

Light(sub-GeV)dark matter has gained increasing interest in terms of direct *** dark matter is a promising candidate that can generate detectable nuclear recoil energy within the sub-GeV *** of the large kinetic energy,its interactions with the nucleus are predominantly governed by inelastic scattering,including quasi-elastic and deep inelastic *** this work,we calculated the inelastic effects in dark matter-Earth scattering mediated by a vector *** analysis revealed that the impact of inelastic scattering relies on the mediator mass and the kinetic energy spectrum of dark *** results exhibited considerable disparity:the upper bounds of the exclusion limit for the spin-independent cross-section between accelerated dark matter and nuclei via a heavy mediator differ by several tens of times when inelastic scattering is considered.

关键词： accelerated dark matter inelastic scattering direct detection experiment

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Algorithm for complex network diameter based on distance matrix

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Journal of Systems Engineering and Electronics 2018年第2期29卷 336-342页

作者： CHEN bin zhu Weixing LIU Ying Institute of Command Information System PLA University of Science and Technology College of Computer Science and Engineering Sanjiang University Institute of Field Engineering PLA University of Science and Technology

The network diameter is an important characteristic parameter of a complex network. Calculation for a large-scale complex network’s diameter has been an important subject in the study of complex networks. If the network diameter is calculated directly, the problem mainly exists in efficiency for searching and counting the shortest paths. If the network diameter is calculated indirectly by studying the statistical function about the relationship between the network diameter and parameters affecting the diameter, the problems not only exist in the efficiency of statistic, but also exist in the function which may be not applicable to all kinds of networks. An algorithm for the complex network diameter based on the k order distance matrix is proposed with a matrix multiplication approach, and a mathematical proof for the algorithm correctness is given as well. Furthermore, some relevant propositions and deductions for reducing the complexity of this algorithm are put forward. With a good theoretical basis and a simple calculation process, this algorithm can be used to calculate the diameter of a large-scale complex network with small-world effect more accurately and efficiently. Two cases about the advanced research projects agency(ARPA) network model and the Chinese airline network model are adopted to verify the effect of this algorithm.

关键词： complex network network diameter distance matrix

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Shear behaviours of cohesionless mixed soils using the DEM:The influence of coarse particle shape

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Particuology 2021年第2期19卷 151-165页

作者： Yangui zhu jian Gong Zhihong Nie School of Civil Engineering Central South UniversityChangsha 410075China

The coarse particles in mixed soils can be cobbles or gravels,with the main difference being their roundness(an indicator describing particle shape characteristics at an intermediate scale).The influence of coarse particle shape(i.e.,roundness)on the macroscopic and microscopic shear behaviours of cohesionless mixed soils with various fines contents(FCs)was investigated via the discrete element method in this *** shapes of coarse particles were formed using the rotation-invariant spherical harmonic method proposed by previous *** equation was proposed to predict the initial void ratios of samples in this study.A decrease in the roundness of coarse particles can increase the peak friction angle(FC≤40%)and critical friction angle(FC≤30%).As the roundness of coarse particles decreases,the peak dilatancy angle initially increases and then decreases(FC≤20%).Furthermore,it was found that the roundness of coarse particles hardly affects the classification of cohesionless mixed soils,as determined by probing the percentage contributions of coarse-coarse,coarse-fine,and fine-fine *** cohesionless mixed soils change from an underfilled structure to an interactive-underfilled structure at the critical state,the main forms of coarse-coarse contacts were ***,the force-fabric anisotropy mechanisms of the influences of the roundness and rolling resistance coefficient of coarse particles on the shear strengths of cohesionless mixed soils were found to be different.

关键词： Cohesionless mixed soils Particle shape Roundness Shear behaviours Discrete element method

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Mean estimation over numeric data with personalized local differential privacy

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Frontiers of Computer Science 2022年第3期16卷 183-192页

作者： Qiao XUE Youwen zhu jian WANG College of Computer Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 211106China Guangxi Key Laboratory of Trusted Software Guilin University of Electronic TechnologyGuilin 541004China School of Cyber Security Gansu University of Political Science and LawLanzhou 730070China

The fast development of the Internet and mobile devices results in a crowdsensing business model,where individuals(users)are willing to contribute their data to help the institution(data collector)analyze and release useful ***,the reveal of personal data will bring huge privacy threats to users,which will impede the wide application of the crowdsensing *** settle the problem,the definition of local differential privacy(LDP)is ***,to respond to the varied privacy preference of users,resear-chers propose a new model,i.e.,personalized local differential privacy(PLDP),which allow users to specify their own privacy *** this paper,we focus on a basic task of calculating the mean value over a single numeric attribute with *** on the previous schemes for mean estimation under LDP,we employ PLDP model to design novel schemes(LAP,DCP,PWP)to provide personalized privacy for each *** then theoretically analysis the worst-case variance of three proposed schemes and conduct experiments on synthetic and real datasets to evaluate the performance of three *** theoretical and experimental results show the optimality of PWP in the low privacy regime and a slight advantage of DCP in the high privacy regime.

关键词： personalized local differential privacy mean estimation crowdsensing model

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