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Thirty-day mortality of patients with hip fracture during COVID-19 pandemic and pre-pandemic periods:A systematic review and metaanalysis

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World journal of Orthopedics 2021年第1期12卷 35-50页

作者： Sujit kumar Tripathy Paulson Varghese Sibasish Panigrahi Bijnya Birajita Panda Sandeep Velagada Samrat Smrutiranjan Sahoo Monappa A Naik sharath K Rao Department of Orthopedics All India Institute of Medical SciencesBhubaneswar 751019India Department of Orthopedics All India Institute of Medical SciencesBhubaneswarBhubaneswar 751019India Department of Ophthalmology SCB Medical CollegeCuttack 753007India Department of Orthopedics All India Institute of Medical SciencesNagpur 441108India Department of Orthopedics Kasturba Medical CollegeManipal Academy of Higher EducationManipalUdupiKarnataka 576104India Department of Orthopedics Kasturba Medical CollegeManipal Academy of Higher EducationManipalUdupiKarnatakaManipal 576104India

BACKGROUND Timely intervention in hip fracture is essential to decrease the risks of perioperative morbidity and ***,limitations of the resources,risk of disease transmission and redirection of medical attention to a more severe infective health problem during coronavirus disease 2019(COVID-19)pandemic period have affected the quality of care even in a surgical *** To compare the 30-d mortality rate and complications of hip fracture patients treated during COVID-19 pandemic and pre-pandemic *** The search of electronic databases on 1st August 2020 revealed 45 studies related to mortality of hip fracture during the COVID-19 pandemic and pre-pandemic *** careful screening,eight studies were eligible for quantitative and qualitative analysis of *** The pooled data of eight studies(n=1586)revealed no significant difference in 30-d mortality rate between the hip fracture patients treated during the pandemic and pre-pandemic periods[9.63%vs 6.33%;odds ratio(OR),0.62;95%CI,0.33,1.17;P=0.14].Even the 30-d mortality rate was not different between COVID-19 non-infected patients who were treated during the pandemic time,and all hip fracture patients treated during the pre-pandemic period(OR,1.03;95%CI,0.61,1.75;P=0.91).A significant difference in mortality rate was observed between COVID-19 positive and COVID-19 negative patients(OR,6.99;95%CI,3.45,14.16;P<0.00001).There was no difference in the duration of hospital stay(OR,-1.52,95%CI,-3.85,0.81;P=0.20),overall complications(OR,1.62;P=0.15)and incidence of pulmonary complications(OR,1.46;P=0.38)in these two-time ***,the preoperative morbidity was more severe,and there was less use of general anesthesia during the pandemic *** There was no difference in 30-d mortality rate between hip fracture patients treated during the pandemic and pre-pandemic ***,the mortality risk was higher in COVID-19 positive patients compared to COVID-19 negativ

关键词： Hip fracture Femur neck fracture Trochanter fracture Mortality Pandemic COVID-19

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Combustion synthesis of Ce^(3+), Eu^(3+) and Dy^(3+) activated NaCaPO_4 phosphors

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journal of Rare Earths 2011年第6期29卷 527-535页

作者： K N Shinde S j Dhoble Animesh kumar Department of Physics RTM Nagpur University National Environmental Engineering Research Institute

The preparation of NaCaPO4 doped with rare earth （RE） ions Ce3＋, Eu3＋ and Dy3＋ by combustion method was described. Under UV excitation （251 nm） of NaCaPO4：Ce3＋ showsd emission （367 nm） in UV range. When NaCaPO4：Dy3＋ phosphor was excited at 349 nm, the emission spectrum showed intense bands at 482 nm （blue） and 576 nm （yellow）. In Eu activated NaCaPO4 phosphor, the emission spectrum showed a dominant peak at 594 nm （orange） while others were at 614 and 621 nm （red） when excited at 393 nm. The prepared phosphor was characterized by X-ray diffraction （XRD）, scanning electron microscope （SEM） and photoluminescence （PL） measurement. Thus, the photoluminescence behavior of NaCaPO4：Ce3＋ was strongly suggested for scintillator. Likewise, Eu3＋ and Dy3＋ activated NaCaPO4 phosphors were recommended for near-UV white light-emitting diodes （LEDs）.

关键词： combustion synthesis photoluminescence phosphor scintillator solid state lighting rare earths

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Engineering polymer nanoparticles using cell membrane coating technology and their application in cancer treatments:Opportunities and challenges

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Nano Materials Science 2022年第4期4卷 295-321页

作者： Kai Guo Nanyang Xiao Yixuan Liu Zhenming Wang judit Tóth jános Gyenis Vijay kumar Thakur Ayako Oyane Quazi T.H.Shubhra Stomatology Hospital of Guangzhou Medical University Guangzhou Medical UniversityGuangzhou510140China Department of Microbiology The University of ChicagoChicagoIL60637USA Department of Pathology School of Basic Medical SciencesNanjing Medical UniversityNanjing21116China State Key Laboratory of Oral Diseases West China Hospital of StomatologySichuan UniversityChengdu610041China Research Centre for Natural Sciences Institute of Materials and Environmental Chemistry1117BudapestMagyar Tudósok Körútja 2Hungary University of Pannonia Egyetem u.10H-8200VeszprémHungary Nanomaterials Research Institute National Institute of Advanced Industrial Science and Technology(AIST)Tsukuba305-8565Japan School of Engineering University of Petroleum&Energy Studies(UPES)Dehradun 248007India

Nanotechnology has revolutionized cancer drug delivery,and recent research continues to focus on the development of“one-size-fits-all,”i.e.,“all-in-one”delivery *** nanomedicines can address significant shortcomings of conventional therapy,biological barriers remain a challenge in their delivery and accumulation at diseased *** achieve long circulation time,immune evasion,and targeted accumulation,conventional nanocarriers need modifications,e.g.,PEGylation,peptide/aptamer attachment,*** such modification is a biomimetic coating using cell membrane(CM),which can offer long circulation or targeting,or *** top-down CM coating process is facile and can provide some advantageous features over surface modification by synthetic ***,an overview is provided on the engineering of CM camouflaged polymer nanoparticles.A short section on CM and the development of CM coating technology has been *** description of the preparation and characterization of CM camouflaged polymer NPs and their applications in cancer treatment has been reported.A brief comparison between CM coating and PEGylation has been *** targeting approaches to achieve tumor-specific delivery of CM coated NPs have been summarized ***,this review will give the readers a nice picture of CM coated polymer NPs,along with their opportunities and challenges.

关键词： Cell membrane(CM) Nanoparticles(NPs) Cancer Camouflage Biomimetic coating Drug delivery

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Effect of wood dust type on mechanical properties, wear behavior, biodegradability, and resistance to natural weathering of wood-plastic composites

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Frontiers of Structural and Civil Engineering 2019年第6期13卷 1446-1462页

作者： Sawan kumar Ajitanshu VEDRTNAM S.j.PAWAR Department of Applied Mechanics Motilal Nehru National Institute of Technology AllahabadAllahabadUP 211004India Department of Mechanical Engineering Invertis UniversityBareillyUP 243001India Vinoba Bhave Research Institute AllahabadUP 211004India Translational Research Centre Institute of Advanced MaterialsVBRIL inkoping 58330Sweden

The present work reports the inclusion of different proportions of Mango/Sheesham/Mahogany/Babool dust to polypropylene for improving mechanical,wear behavior and biodegradability of wood-plastic composite(WPC).The wood dust(10%,15%,20%by weight)was mixed with polypropylene granules and WPCs were prepared using an injection molding *** mechanical,wear,and morphological characterizations of fabricated WPCs were carried out using standard ASTM methods,pin on disk apparatus,and scanning electron microscopy(SEM),***,the biodegradability and resistance to natural weathering of WPCs were evaluated following ASTM D5338-11 and ASTM D1435-99,*** WPCs consisting ofBabool and Sheesham dust were having superior mechanical properties whereas the WPCs consisting of Mango and Mahogany were more wear *** was found that increasing wood powder proportion results in higher Young's modulus,lesser wear rate,and decreased stress at *** WPCs made of Sheesham dust were least *** was noticed that the biodegradability corresponds with resistance to natural weathering;more biodegradable WPCs were having the lesser resistance to natural weathering.

关键词： wood-plastic composites mechanical testing wear biodegradability injection molding weathering

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Tsc2 mutation induces renal tubular cell nonautonomous disease

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Genes & Diseases 2022年第1期9卷 187-200页

作者： Prashant kumar Fahad Zadjali Ying Yao Daniel johnson Brian Siroky Aristotelis Astrinidis Peter Vogel Kenneth W.Gross john j.Bissler Department of Pediatrics University of Tennessee Health Science Center and Le Bonheur Children's HospitalMemphisTN 38103USA Children's Foundation Research Institute(CFRI) Le Bonheur Children's HospitalMemphisTN 38105USA Department of Clinical Biochemistry College of Medicine&Health SciencesSultan Qaboos UniversityMuscat 123Oman Molecular Bioinformatics Center University of Tennessee Health Science CenterMemphisTN 38163USA Department of Veterinary Pathology St.Jude Children's Research HospitalMemphisTN 38105USA Department of Molecular and Cellular Biology Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Pediatric Medicine Department St.Jude Children's Research HospitalMemphisTN 38105USA

TSC renal cystic disease is poorly understood and has no approved *** a new principal cell-targeted murine model of Tsc cystic disease,the renal cystic epithelium is mostly composed of type A intercalated cells with an intact Tsc2 gene confirmed by sequencing,although these cells exhibit a Tsc-mutant disease *** used a newly derived targeted murine model in lineage tracing and extracellular vesicle(EV)characterization experiments and a cell culture model in EV characterization and cellular induction experiments to understand TSC *** lineage tracing experiments,we found principal cells undergo clonal expansion but contribute very few cells to the *** determined that cystic kidneys contain more interstitial EVs than noncystic kidneys,excrete fewer EVs in urine,and contain EVs in cyst ***,the loss of Tsc2 gene in EV-producing cells greatly changes the effect of EVs on renal tubular epithelium,such that the epithelium develops increased secretory and proliferative pathway *** demonstate that the mTORC1 pathway activity is independent form the EV production,and that the EV effects for a single cell line can vary *** cystogenesis involves significant contribution from genetically intact cells conscripted to the mutant phenotype by mutant cell derived EVs.

关键词： Cell nonautonomous trait Polycystic kidney disease Renalcystogenesis Tuberous sclerosis complex

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Recombinase Polymerase Amplification Based Rapid Detection of Aroma Gene in Rice

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Rice science 2023年第2期30卷 96-99,I0010-I0013页

作者： Amrita BANERjEE S.BHARTI j.kumar P.SAR PRIYAMEDHA N.P.MANDAL S.SARKAR Somnath ROY Central Rainfed Upland Rice Research Station Indian Council of Agricultural Research(ICAR)-National Rice Research InstituteHazaribagJharkhand 825301India Department of Biotechnology Vinoba Bhave UniversityHazaribagJharkhand 825301India Crop Improvement Division ICAR-National Rice Research InstituteCuttackOdisha 753006India

Recombinase polymerase amplification(RPA) has been emerged as an alternative to PCR due to its high specificity and sensitivity in diagnostics of animal and plant pathogens. In this study, an RPA protocol was develope... 详细信息

关键词： specificity Rec emerged

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Comparison of the‘Seattle’and‘International’Criteria Electrocardiogram Interpretation in Division II Female Collegiate Athletes:A Preliminary Study

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journal of Science in Sport and Exercise 2023年第3期5卷 274-279页

作者： Ludmila Cosio-Lima N.kumar Brooke L.Adlof j.Simpson A.Crawley Y.Lee University of West Florida 11000 University Parkway#72/220PensacolaFL 32514USA

Purpose A 12-lead electrocardiogram(ECG)is a screening tool to detect abnormalities that may predispose athletes to sud-den cardiac *** standardized criteria have been introduced to better interpret ECG data,however this research has predominantly focused on male *** is important to include female athletes in research to better define ECG character-istics in this *** purpose of this study was to compare the Seattle and International Criteria ECG abnormalities in Division II female collegiate athletes of various *** Fifty-six females(age 20.2±1.4 years;height 1.70±0.7 m;weight 69.5±8.9 kg)completed a resting 12-lead ECG *** data was classified as‘normal’and‘abnormal’according to the parameters of each criterion and abnormal conditions were ***-square analysis was used to assess statistical comparisons between *** There was a significant difference in abnormal classifications as the total number of ECGs identified as abnormal using the Seattle Criteria decreased from 12(21.4%)to 2(3.6%)when using the International Criteria(P<0.05).African American athletes had a higher number of abnormal ECG’s compared to White and Latina athletes using the Seattle Criteria(P=0.03).Conclusions The International Criteria significantly reduces the total number of abnormal ECG readings in female collegiate athletes compared to the Seattle Criteria and did not overly identify African American athletes with *** research is necessary to expand on this study and clearly define criteria for female athletes of various ethnicities.

关键词： 12-lead ECG Female athletes Sudden cardiac death ECG abnormalities

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Breast Cancer Detection Using Breastnet-18 Augmentation with Fine Tuned Vgg-16

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Intelligent Automation & Soft Computing 2023年第5期36卷 2363-2378页

作者： S.j.K.jagadeesh kumar P.Parthasarathi Mofreh A.Hogo Mehedi Masud jehad F.Al-Amri Mohamed Abouhawwash Department of Computer Science and Engineering Kathir College of EngineeringCoimbatore641062India Department of Computer Science and Engineering Bannari Amman Institute of TechnologySathyamangalam638401TamilnaduIndia Electrical Engineering Department Faculty of EngineeringBenha UniversityBenha13518Egypt Department of Computer Science College of Computers and Information TechnologyTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Department of Information Technology College of Computers and Information TechnologyTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Department of Mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational Mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA

Women from middle age to old age are mostly screened positive for Breast cancer which leads to *** over the past decades,the overall sur-vival rate in breast cancer has improved due to advancements in early-stage diag-nosis and tailored *** all hospital brings high awareness and early detection technologies for breast *** increases the survival rate of *** traditional breast cancer treatment takes so long,early cancer techniques require an automation *** research provides a new methodol-ogy for classifying breast cancer using ultrasound pictures that use deep learning and the combination of the best ***,after successful learning of Convolutional Neural Network(CNN)algorithms,data augmentation is used to enhance the representation of the feature *** it uses BreastNet18 withﬁne-tuned VGG-16 model for pre-training the augmented *** feature classiﬁcation,Entropy controlled Whale Optimization Algorithm(EWOA)is *** features that have been optimized using the EWOA were utilized to fuse and optimize the *** identify the breast cancer pictures,training classiﬁers are *** using the novel probability-based serial technique,the best-chosen characteristics are fused and categorized by machine learning *** main objective behind the research is to increase tumor prediction accuracy for saving human *** testing was performed using a dataset of enhanced Breast Ultrasound Images(BUSI).The proposed method improves the accuracy com-pared with the existing methods.

关键词： Deep learning classiﬁcation data augmentation feature extraction the fusion of features breast cancer optimization classiﬁcation

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QoS Constrained Network Coding Technique to Data Transmission Using IoT

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Computer Systems Science & Engineering 2022年第11期43卷 531-544页

作者： A.Sathishkumar T.Rammohan S.Sathish kumar j.Uma K.Srujan Raju Aarti Sangwan M.Sivachitra M.Prabu Department of ECE The Kavery Engineering CollegeMecheri636453TamilnaduIndia Department of EEE Karpagam College of EngineeringCoimbatore641032India Department of EEE M.Kumarasamy College of EngineeringKarur639113India Department of Computer Science and Engineering CMR Technical CampusHyderabad501401India Department of CST Manav Rachna UniversityFaridabad121004India Department of EEE Kongu Engineering CollegePerundurai638060India Department of EEE Nandha Engineering CollegePerunduraiTamilnadu638052India

The research work presents,constrained network coding technique to ensure the successful data transmission based composite channel cmos technology using dielectric *** charge fragmentation and charge splitting are two components of the filtered switch domino(FSD)*** behavior of selected switching is achieved using generator called conditional pulse generator which is employed in Multi Dynamic Node Domino(MDND)*** FSD and MDND technique need wide area compared to existing single nodekeeper domino *** aim of this research is to minimize dissipation of power and to achieve less consumption of *** proposed research,works by introducing the method namely Interference and throughput aware Optimized Multicast Routing Protocol(IT-OMRP).The main goal of this proposed research method is to introduce the system which can forward the data packets towards the destination securely and *** achieve the bandwidth and throughput in optimized data transmission,proposed multicast tree is selected by Particle Swarm Optimization which will select the most optimal host node as the branches of multi cast *** node selection is done by considering the objectives residual energy,residual bandwidth and *** node selection multi cast routing is done with the concern of interference to ensure the reliable and successful data *** case of transmission range size is higher than the coverage sense range,successful routing is ensured by selecting secondary host forwarders as a backup which will act as intermediate relay *** NS2 simulator is used to evaluate research outcome from which it is proved that the proposed technique tends to have increased packet delivery ratio than the existing work.

关键词： Multicast routing optimal node selection secondary relay nodes probability of interference residual energy bandwidth throughput

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Escherichia coli O157:H7 sepsis following fecal microbiota transplant in an IgA-deficient inflammatory bowel disease patient

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Gastroenterology Report 2022年第1期10卷 609-611页

作者： Landen S.Burstiner jared Silver Logan j.Burstiner Arian Teymoorian kumar Pallav Demarre jones Anna Owings Sarah Glover Nova Southeastern University Dr.Kiran C.Patel College of Osteopathic Medicine DavieFLUSA Department of Gastroenterology University of Mississippi Medical CenterJacksonMSUSA Department of Medicine Division of RheumatologyImmunologyand AllergyBrigham and Women’s HospitalHarvard Medical SchoolBostonMAUSA Department of Medicine Memorial Healthcare SystemHollywoodFLUSA Department of Gastroenterology GI Associates&Endoscopy CenterFlowoodMSUSA

Introduction Clostridioides difficile infection(CDI)is a common gastrointestinal illness worldwide,with increased prevalence and worse outcomes in patients with inflammatory bowel disease(IBD)[1].Fecal microbiota transplant(FMT)is an effective treatment for recurrent CDIs(RCDIs)with minimal serious adverse events(SAEs)reported[2].While immunosuppressive medications increase susceptibility to infections,studies have shown that FMT does not increase SAE risk in immunocompromised patients(including IBD patients on immunosuppressive therapy)[3].

关键词： O157:H7 inflammatory patients

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