Thirty-day mortality of patients with hip fracture during COVID-19 pandemic and pre-pandemic periods:A systematic review and metaanalysis

作     者：Sujit Kumar Tripathy Paulson Varghese Sibasish Panigrahi Bijnya Birajita Panda Sandeep Velagada Samrat Smrutiranjan Sahoo Monappa A Naik Sharath K Rao 

作者机构：Department of OrthopedicsAll India Institute of Medical SciencesBhubaneswar 751019India Department of OrthopedicsAll India Institute of Medical SciencesBhubaneswarBhubaneswar 751019India Department of OphthalmologySCB Medical CollegeCuttack 753007India Department of OrthopedicsAll India Institute of Medical SciencesNagpur 441108India Department of OrthopedicsKasturba Medical CollegeManipal Academy of Higher EducationManipalUdupiKarnataka 576104India Department of OrthopedicsKasturba Medical CollegeManipal Academy of Higher EducationManipalUdupiKarnatakaManipal 576104India 

出 版 物：《World Journal of Orthopedics》 (世界骨科杂志（英文版）)

年 卷 期：2021年第12卷第1期

页      面：35-50页

学科分类：0403[教育学-体育学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Hip fracture Femur neck fracture Trochanter fracture Mortality Pandemic COVID-19 

摘      要：BACKGROUND Timely intervention in hip fracture is essential to decrease the risks of perioperative morbidity and ***,limitations of the resources,risk of disease transmission and redirection of medical attention to a more severe infective health problem during coronavirus disease 2019(COVID-19)pandemic period have affected the quality of care even in a surgical *** To compare the 30-d mortality rate and complications of hip fracture patients treated during COVID-19 pandemic and pre-pandemic *** The search of electronic databases on 1st August 2020 revealed 45 studies related to mortality of hip fracture during the COVID-19 pandemic and pre-pandemic *** careful screening,eight studies were eligible for quantitative and qualitative analysis of *** The pooled data of eight studies(n=1586)revealed no significant difference in 30-d mortality rate between the hip fracture patients treated during the pandemic and pre-pandemic periods[9.63%vs 6.33%;odds ratio(OR),0.62;95%CI,0.33,1.17;P=0.14].Even the 30-d mortality rate was not different between COVID-19 non-infected patients who were treated during the pandemic time,and all hip fracture patients treated during the pre-pandemic period(OR,1.03;95%CI,0.61,1.75;P=0.91).A significant difference in mortality rate was observed between COVID-19 positive and COVID-19 negative patients(OR,6.99;95%CI,3.45,14.16;P0.00001).There was no difference in the duration of hospital stay(OR,-1.52,95%CI,-3.85,0.81;P=0.20),overall complications(OR,1.62;P=0.15)and incidence of pulmonary complications(OR,1.46;P=0.38)in these two-time ***,the preoperative morbidity was more severe,and there was less use of general anesthesia during the pandemic *** There was no difference in 30-d mortality rate between hip fracture patients treated during the pandemic and pre-pandemic ***,the mortality risk was higher in COVID-19 positive patients compared to COVID-19 negativ