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Global concerns related to water biology and security:The need for language and policies that safeguard living resources versus those that dilute scientific knowledge

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Water Biology and Security 2023年第4期2卷 136-146页

作者： Robert M.Hughes james R.Karr Robert L.Vadas Dominick A.DellaSala Marcos Callisto Maria joao Feio Teresa Ferreira Neels Kleynhans Renata Ruaro Chris O.Yoder j.hal michael Amnis Opes Institute 2895 SE GlennCorvallisOR97333USA Department of Fisheries Wildlife&Conservation SciencesOregon State UniversityCorvallisOR97331USA School of Aquatic and Fishery Sciences University of WashingtonSeattleWA98915USA Karr Consulting 102 Galaxy View CourtSequimWA98382USA 2909 Boulevard Rd.SE OlympiaWA98501-3971USA Wild Heritage a Project of Earth Island Institute2150 Allston WayBerkeleyCA94704-1346USA Departamento de Genetica Ecologia e EvolucaoInstituto de Ciencias BiologicasUniversidade Federal de Minas GeraisAvenida Antonio Carlos 6627CEP 31270-901Belo HorizonteMGBrazil Associate Laboratory ARNET Marine and Environmental Sciences CentreDepartment of Life SciencesUniversity of CoimbraCoimbraPortugal Forest Research Centre&Associate Laboratory TERRA University of LisbonTapada da Ajuda1349-017LisbonPortugal Department of Water Affairs and Forestry(retired) 8th Avenue 771Wonderboom South0084PretoriaSouth Africa Graduate Program in Environmental Science and Technology Federal Technological University of Parana81280-340CuritibaPRBrazil Midwest Biodiversity Institute 4673 Northwest ParkwayHilliardOH43026USA Ecologists Without Borders OlympiaWAUSA

Increasingly,scientists and non-scientists,especially employees of government agencies,tend to use weak or equivocal language when making statements related to science policy and governmental *** use recent publications to provide examples of vague language versus examples of strong language when authors write about regulating anthropogenic pressures on natural *** language is common in agency reports,policy documents,and even scientific papers published by *** language limits success in regulating anthropogenic pressures on natural *** challenge must be recognized and countered as a driver of the condition of water and associated *** also list sources of vague wording,provide global examples of how ambiguous language and political influences have contributed to water resource degradation,discuss the recent history of science censorship,and offer possible solutions for more direct scientific *** found that:(1)equivocal language was especially common in concluding statements and not only by government employees;(2)authors discussed confusing language concerns in an agency publication;and(3)agency employees sometimes used active,strong *** drivers of weak language include:(1)holding on to old paradigms and resisting new knowledge;(2)scientific uncertainty;(3)institutional manuscript review policies;(4)employment and funding insecurity;and(5)avoiding the appearance of *** associated with euphemistic language included climate change,flow and physical habitat alteration,dams,agriculture,mining,forestry,and fisheries,as well as resistance towards monitoring,assessing,and reporting ecological *** for mitigating equivocal language involve employment protections and greater focus on scientific *** conclude that natural resource scientists should resist calls to employ imprecise ***,they should be strong advocates for prescriptive and protective natura

关键词： Corruption Ethics Science censoring Science policy Water resource degradation

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Design and synthesis of synthetic promoters for consistency of gene expression across growth phases and scale in ***

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Synthetic and Systems Biotechnology 2024年第2期9卷 330-339页

作者： Kristin V.Presnell Omar Melhem Sarah M.Coleman Nicholas j.Morse hal S.Alper McKetta Department of Chemical Engineering The University of Texas at Austin200E Dean Keeton St.Stop C0400AustinTX78712USA Institute for Cellular and Molecular Biology The University of Texas at Austin2500 Speedway AvenueAustinTX78712USA

Metabolic engineering and synthetic biology endeavors benefit from promoters that perform consistently(or robustly)with respect to cellular growth phase(exponential and stationary)and fermentation scale(microtiter plates,tubes,flasks,and bioreactors).However,nearly all endogenous promoters(especially in Saccharomyces cerevisiae)do not perform in this *** this work,a hybrid promoter engineering strategy is leveraged to create novel synthetic promoters with robustness across these *** a multi-dimensional RNA-seq dataset,promoters with specific phase dependencies were *** enriched with functional transcription factors were identified using MEME *** motif-containing fragments could impart activity dependence in the opposing ***,we obtain two new promoters with high and consistent expression across both phases by increasing the exponential phase activity of the starting stationary-phase scaffold by 38 and 23-fold ***,we show that these promoters function consistently across various laboratory growth scales over time in a microtiter plate and in ***,this work presents and validates a new strategy for engineering promoters in *** with high levels of expression that are robust to cellular growth phase and the scale of the culture.

关键词： endogenous synthetic stationary

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日本真牡蛎(Grassostrea gigas)抗夏季死亡的育种试验

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国外水产 1981年第1期 25-29页

作者： j.hal Beattie 王颖洁

迄今为止所取得的试验结果表明,选育能够抗高温的牡蛎子代具有很大的潜力.子一代是从日本愿种牡蛎产生的,它可以耐受21℃的高温.7个子代中的两个在高温下的成活率显著地要比同龄的日本原种的成活率高.而且,每一个子代都显示了较好的成活... 详细信息

迄今为止所取得的试验结果表明,选育能够抗高温的牡蛎子代具有很大的潜力.子一代是从日本愿种牡蛎产生的,它可以耐受21℃的高温.7个子代中的两个在高温下的成活率显著地要比同龄的日本原种的成活率高.而且,每一个子代都显示了较好的成活率.性腺成熟度的变化可能是本报告所描述的,影响到晚秋试验结果的一个易变因子.进一步的试验将在仲夏到晚夏性腺发育成熟期间进行.

关键词：亲贝苗种子一代 Grassostrea gigas 子代杂交后代后期幼体诱导产卵原种日本

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Transporting droplets through surface anisotropy

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Microsystems & Nanoengineering 2015年第1期1卷 74-81页

作者： hal R.Holmes Karl F.Böhringer Department of Bioengineering University of WashingtonSeattleWA 98195USA Department of Electrical Engineering University of WashingtonSeattleWA 98195USA

This review article examines digital microfluidic systems that manipulate droplets through surface *** systems are categorized as surface tension driven or contact line *** tension driven systems include electrowetting on dielectric,Marangoni flow on microheater arrays,and chemical gradient surfaces,whereas contact line driven systems include anisotropic ratchet conveyors,nanostructured Parylene ratchets,and tilted pillar *** article describes the operating principles and outlines the fabrication procedures for each *** also present new equations that unify several previous models of contact line driven *** strengths and weaknesses of each system are compared,with a focus on their ability to perform the generation,switching,fusion,and fission of ***,we discuss current and potential future applications of these systems.

关键词： droplets digital microfluidics electrowetting thermocapillary forces contact line oscillation

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Applying Downscaled Global Climate Model Data to a Groundwater Model of the Suwannee River Basin, Florida, USA

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American journal of Climate Change 2016年第4期5卷 526-557页

作者： Eric Swain j. hal Davis Caribbean-Florida Water Science Center U.S. Geological Survey Davie FL USA Retired US Geological Survey Davie FL USA

The application of Global Climate Model (GCM) output to a hydrologic model allows for comparisons between simulated recent and future conditions and provides insight into the dynamics of hydrology as it may be affected by climate change. A previously developed numerical model of the Suwannee River Basin, Florida, USA, was modified and calibrated to represent transient conditions. A simulation of recent conditions was developed for the 372-month period 1970-2000 and was compared with a simulation of future conditions for a similar-length period 2039-2069, which uses downscaled GCM data. The MODFLOW groundwater-simulation code was used in both of these simulations, and two different MODFLOW boundary condition “packages” (River and Streamflow-Routing Packages) were used to represent interactions between surface-water and groundwater features. The hydrologic fluxes between the atmosphere and landscape for the simulation of future conditions were developed from dynamically downscaled precipitation and evapotranspiration (ET) data generated by the Community Climate System Model (CCSM). The downscaled precipitation data were interpolated for the Suwannee River model grid, and the downscaled ET data were used to develop potential ET and were interpolated to the grid. The future period has higher simulated rainfall (10.8 percent) and ET (4.5 percent) than the recent period. The higher future rainfall causes simulated groundwater levels to rise in areas where they are deep and have little ET in either the recent or future case. However, in areas where groundwater levels were originally near the surface, the greater future ET causes groundwater levels to become lower despite the higher projected rainfall. The general implication is that unsaturated zone depth could be more spatially uniform in the future and vegetation that requires a range of conditions (substantially wetter or drier than average) could be detrimentally affected. This vegetation would include wetland species,

关键词： Groundwater Climate Model River System Downscaling

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火花源光发射光谱法分析中测量不确定度的表述及原材料规格一致性概率的计算

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冶金分析 2012年第1期32卷 19-22页

作者： Edmund halász j-M Bhlen 赛默飞世尔科技有限公司瑞士埃库布朗

根据ISO 17025,每年有越来越多的实验室开始使用光发射光谱仪(OES)。ISO17025的遵守提升了评估和报道测量不确定度的重要性。《测量不确定度表示指南》(GUM)提供了不确定度分析的指导方法。不过,这些指导方针的实施是一项艰巨的任务,尤... 详细信息

根据ISO 17025,每年有越来越多的实验室开始使用光发射光谱仪(OES)。ISO17025的遵守提升了评估和报道测量不确定度的重要性。《测量不确定度表示指南》(GUM)提供了不确定度分析的指导方法。不过,这些指导方针的实施是一项艰巨的任务,尤其是不熟悉必要的数学和统计学概念时。因此,试验和校准人员必须经常寻找现成的工具以满足分析需求。本文报道了赛默飞世尔科技有限公司实施的分析软件,用于测量不确定度的计算。此外,还描述了基于不确定度知识的应用,以用于计算产品一致性的概率。

关键词：火花源光发射光谱测量不确定度置信区间一致性测试风险分析

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DETERMINATION OF VLF PATHS IN 3D FIELD-ALIGNED DUCTS

DETERMINATION OF VLF PATHS IN 3D FIELD-ALIGNED DUCTS

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1997 International Symposium on Radio Propagation(ISRP’97)

作者： hal j.Strangeways Department of Electronic and Electrical Engineering University of Leeds

＜正＞Ducted VLF waves can interact via cyclotron resonance with counterstreaming electrons in or near the equatorial plane resulting in particle precipitation giving localised electron density enhancements in the D-region（LIEs） which then cause phase and amplitude perturbations on subionosphere VLF propagation（Trimpi effect）. Satellite observations have been made of precipitating electrons associated with ducted whistlers and the extent of the precipitation region at the satellite altitude in the lower ionosphere has been estimated by the length of satellite orbit for which the precipitation events were *** size of precipitation regions has also been estimated by monitoring perturbations of two or more VLF transmitters for sub-ionosphere propagation using a network of receiving *** is found, however,that the dimensions of both typical LIE enhancements and the extent of precipitation regions in the lower ionosphere appear to be larger than might be expected from observations of ducted whistlers both on the ground and in situ aboard *** investigate this,the paths of VLF signals in ducts（geomagnetic field aligned enhancements of electron density） are determined using a 3D magnetospheric ray-tracing model including 3D *** calculations show that the ray path excursions are reduced in bothΔL andΔΦ（longitude） as the rays propagate upwards in the duct from low altitude（～1000 km） to the equatorial *** implies that precipitation regions and LIEs would typically have smaller dimensions in L-value that low altitude whistler duct widths measured by the spatial extent of the whistler-mode ***,this appears to be contrary to general *** account for this discrepancy,ray paths are also determined for ducts which widen between low altitude and the equatorial *** show that a better fit with experimental observations is obtained but the calculations can still not easily explain significantly wider ducts in L-value in the

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Elevated miR-33a and miR-224 in steatotic chronic hepatitis Cliver biopsies

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World journal of Gastroenterology 2014年第41期20卷 15343-15350页

作者： Gabor Lendvai Katalin jármay Gizella Karácsony Tünde halász Ilona Kovalszky Kornélia Baghy Tibor Wittmann Zsuzsa Schaff András Kiss MTA-SE Tumor Progression Research Group Semmelweis University 1st Department of Medicine University of Szeged 2nd Department of Pathology Semmelweis University 1st Department of Pathology and Experimental Cancer Research Semmelweis University

AIM: To assess the expression of selected microRNAs (miRNA) in hepatitis C, steatotic hepatitis C, noninfected steatotic and normal liver tissues.

关键词： Chronic hepatitis C Steatosis MicroRNA Expression miR-33a miR-224

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德语艺术歌曲选高音卷

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2006年

作者：美国hal Leonard公司编路旦俊译

每一个声乐学生都必须要学习德国艺术歌曲，《德语艺术歌曲选》收集了舒伯特、舒曼、勃拉姆斯等大师最为经典的作品，包括译词和德语发音指导，配以CD，适合各层次水平的声乐学生。

ISBN: (纸本)7540436913

关键词：艺术音乐各国音乐作品

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实在的回归

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作者： (美)哈尔·福斯特(hal Foster)

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