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Tsinghua Science and Technology 2008年第2期13卷 152-156页

作者： S. M. Yoo Y. S. Cho C. C. Lee j. H. Kim C. H. Kim j. K. choi Center for E-Design Korea Institute of Industrial Technology Kwanghee Casting Mfg. Co. R&D Center Doosan Engine Co. Ltd.

Numerical simulations were used to optimize the casting design and conditions for large cast iron castings for marine engines, Simulations of the mold filling and solidification sequences were used to analyze the problems of previous casting conditions with marked improvements for large cylinder liner parts, The amount and positions of chills were optimized to improve the mechanical properties and to minimize the shrinkage and micro porosity in the castings. Ultra sonic testing, penetration testing, and mechanical property testing show no defects in the castings with the productivity significantly increased.

关键词： gray cast iron numerical simulation marine engine cylinder liner chill casting design optimization

Effect of Nucleases on the Cellular Internalization of Fluorescent Labeled DNA-Functionalized Single-Walled Carbon Nanotubes

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Nano Research 2008年第4期1卷 351-360页

作者： Hye Kyung Moon Chan Il Chang Dong-Ki Lee Hee Cheul choi Department of Chemistry Pohang University of Science and Technology(POSTECH)San 31Hyoja-DongNam-guPohang 790-784Korea Department of Chemistry Sungkyunkwan UniversityNatural Science CampusSuwon 440-746Korea

Nuclease effects on the cell internalization of single-walled carbon nanotubes(SWNTs)functionalized with fluorescent-labeled DNA in serum containing cell growth media were *** Cy3-labeled DNA-functionalized SWNT conjugates(Cy3DNA-SWNTs)were incubated with HeLa cells in a fatal bovine serum(FBS)medium,a high fl uorescence intensity was obtained from the cells,indicative for the high level inclusion of ***,the fluorescence intensity was remarkably reduced if Cy3DNA-SWNTs were incubated with cells in the FBS-free *** systematic control experiments revealed that Cy3 dye molecules were released from Cy3DNA-SWNT conjugates by nuclease,and the free Cy3 dyes penetrate into HeLa cell with high *** the actual amounts of SWNTs internalized in the cells were almost identical for both cells incubated in the FBS-present and FBS-absent media according to the Raman measurements,one should be cautious to determine the degree of SWNT internalization based on the fl uorescence intensities especially when the coloring dye molecules were linked to oligonucleotides in nuclease containing media.

关键词： Single-walled carbon nanotube oligonucleotide cellular delivery molecular transporter nuclease

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人体足部三维多结构光声定量和超声成像

国际医学放射学杂志 2022年第4期 480-481页

作者： W.choi E.Park S.jeon Y.Yang B.Park j.Ahn 吴姿倩

摘要目的研究一种三维（3D）无需对比剂双峰光声（PA）/超声（US）成像系统，该系统可在形态上对人类足部可视化，并且还可以无创可靠地量化足部血管参数。资料与方法一

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Current Status of the KSTAR Engineering

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Plasma Science and Technology 2004年第1期6卷 2159-2165页

作者： j.S.Bak K.Kim C.H.choi Y.K.Oh B.C.Kim N.I.Her H.L.Yang G.S.Lee the KSTAR Team Korea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 Korea

As there is substantial progress in the KSTAR tokamak engineering, all themajor structures and sub-systems are under fabrication and in procurement phase. The vacuum vessel,port, cryostat cylinder, lid, and bellows are being rigorously fabricated in the factory. The lowerpart of the KSTAR such as cryostat base and gravity support has been almost finished in itsfabrication. There are also great progresses and significant results in manufacturing of thesuperconducting magnet, including four Toroidal Field (TF) coils, lower and upper PF7 coils whichare the largest Poloidal Field (PF) coils. The TFOO coil, which has been made for test and back-upof the TF magnet system, was successfully tested in the cool-down and current charging. As thefabrications and procurements of major structures have been actively proceeded, assembly works werealso launched from Aug. 2003. More detailed description on these status, results, and plans will bedescribed in this paper.

关键词： KSTAR tokamak vacuum vessel magnet cryostat tokamak assembly

Plasma density measurement and downstream etching of silicon and silicon oxide in Ar/NF3 mixture remote plasma source

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Plasma Science and Technology 2019年第6期21卷 52-57页

作者： H j YEOM D H choi Y S LEE j H KIM D j SEONG S j YOU H C LEE Korea Research Institute of Standards and Science(KRISS) Daejeon 34113 Republic of Korea Department of Physics Chungnam National University Daejeon 34134 Republic of Korea

In this study,plasma density measurements were performed near the plume region of the remote plasma source (RPS) in Ar/NF3 gas mixtures using a microwave cutoff *** measured plasma density is in the range of 1010-1011 cm-3 in the discharge conditions with RPS powers of 2-4 kW and gas pressures of 0.87-4 *** plasma density decreased with increasing gas pressures and RPS powers under various Ar/NF3 mixing *** decrease in the plasma density measured at the fixed measurement position (plume region) can be understood by the reduction of the electron energy relaxation length with increases in the gas pressures and mixing ratio of NF3/(Ar/NF3).We also performed downstream etching of silicon and silicon oxide films in this *** etch rate of the silicon films significantly increases while the silicon oxide is slightly etched with the gas pressures and *** was also found that the etch rate strongly depends on the wafer position on the processing chamber electrode,and that the etch selectivity reached 96-131 in the discharge conditions of RF powers (3730-4180 W) and gas pressures (3.6-4 Torr).

关键词： remote plasma source electron density cutoff probe downstream etch

【评论】单孔机器人系统辅助全直肠系膜切除术与多孔机器人系统辅助全直肠系膜切除术治疗直肠癌的疗效对比:基于一项病例匹配研究的短期结果得出的初步实践经验

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结直肠肛门外科 2023年第5期29卷 521-522页

作者：池诏丞 jEONG M H KIM H j.choi G S 吉林省肿瘤医院结直肠胃腹部肿瘤外二科吉林长春130012 不详

目的:达芬奇单孔(single-port,SP)机器人系统已用于包括结直肠手术在内的多种外科手术。然而,关于其安全性和可行性的实践报道有限。本研究旨在探讨SP机器人系统对比多孔(multiport,MP)机器人系统辅助治疗直肠癌的短期结果。方法:回顾... 详细信息

目的:达芬奇单孔(single-port,SP)机器人系统已用于包括结直肠手术在内的多种外科手术。然而,关于其安全性和可行性的实践报道有限。本研究旨在探讨SP机器人系统对比多孔(multiport,MP)机器人系统辅助治疗直肠癌的短期结果。方法:回顾性分析于2020年接受根治性切除术的直肠癌患者的临床资料,共有43例患者接受了机器人系统辅助全直肠系膜切除术,其中26例(SP组与MP组各13例)被纳入病例匹配队列进行分析。比较两组患者的术中情况、术后结局及病理结果。

关键词：全直肠系膜切除术机器人系统根治性切除术结直肠手术病理结果外科手术直肠癌患者术后结局

Characterization of the plasma mirror system at the j-KAREN-P facility

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High Power Laser Science and Engineering 2022年第4期10卷 26-35页

作者： Akira Kon Mamiko Nishiuchi Yuji Fukuda Kotaro Kondo Koichi Ogura Akito Sagisaka Yasuhiro Miyasaka Nicholas P.Dover Masaki Kando Alexander S.Pirozhkov Izuru Daito Liu Chang Il Woo choi Chang Hee Nam Tim Ziegler Hans-Peter Schlenvoigt Karl Zeil Ulrich Schramm Hiromitsu Kiriyama Kansai Photon Science Institute National Institutes for Quantum Science and TechnologyKyoto 619-0215Japan Center for Relativistic Laser Science Institute for Basic ScienceGwangju 61005Republic of Korea Advanced Photonics Research Institute Gwangju Institute of Science and TechnologyGwangju 61005Republic of Korea Department of Physics and Photon Science Gwangju Institute of Science and TechnologyGwangju 61005Republic of Korea Helmholtz-ZentrumDresden-Rossendorf 01328 DresdenGermany Technische Universitat Dresden 01062 DresdenGermany

We report on the design and characterization of the plasma mirror system installed on the j-KAREN-P laser at the Kansai Photon Science Institute,National Institutes for Quantum Science and *** reflectivity of the single plasma mirror system exceeded 80%.In addition,the temporal contrast was improved by two orders of magnitude at 1 ps before the main ***,the laser near-field spatial distribution after the plasma mirror was kept constant at plasma mirror fluence of less than 100 kj/cm^(2).We also present the results of investigating the difference and the fluctuation in energy,pulse width and pointing stability with and without the plasma mirror system.

关键词： high-powerlasers laser plasma plasma mirror

One hundred and seventy-eight consecutive pancreatoduodenectomies without mortality:role of the multidisciplinary approach

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Hepatobiliary & Pancreatic Diseases International 2011年第4期10卷 415-421页

作者： jaswinder S Samra Raul Alvarado Bachmann julian choi Anthony Gill Michael Neale Vikram Puttaswamy Cameron Bell Ian Norton Sarah Cho Steven Blome Ritchie Maher Sivakumar Gananadha Thomas j Hugh Upper Gastrointestinal Surgical Unit University of SydneyRoyal North Shore HospitalSt LeonardsNSW2065SydneyAustralia Department ofAnatomical Pathology University of SydneyRoyal North Shore HospitalSt LeonardsNSW2065SydneyAustralia Department of Vascular Surgery University of SydneyRoyal North Shore HospitalSt LeonardsNSW2065SydneyAustralia Department of Gastroenterology University of SydneyRoyal North Shore HospitalSt LeonardsNSW2065SydneyAustralia Department of Radiology University of SydneyRoyal North Shore HospitalSt LeonardsNSW2065SydneyAustralia

BACKGROUND:Pancreatoduodenectomy offers the only chance of cure for patients with periampullary ***,however,is a major undertaking in most patients and is associated with a significant morbidity and mortality.A multidisciplinary approach to the workup and follow-up of patients undergoing pancreatoduodenectomy was initiated at our institution to improve the diagnosis,resection rate,mortality and *** undertook the study to assess the effect of this approach on diagnosis,resection rates and short-term outcomes such as morbidity and ***:A prospective database of patients presenting with periampullary cancers to a single surgeon between April 2004 and April 2010 was *** cases were discussed at a multidisciplinary meeting comprising surgeons,gastroenterologists,radiologists,oncologists,radiation oncologists,pathologists and nursing staff.A standardized investigation and management algorithm was *** were graded according to the Clavien-Dindo ***:A total of 295 patients with a periampullary lesion were discussed and 178 underwent pancreatoduodenectomy (resection rate 60%).Sixty-one patients (34%) required either a vascular or an additional organ ***-nine patients experienced complications,of which the commonest was blood transfusion (12%).Thirty-four patients (19%) had major complications,*** 3 or *** was no in-hospital,30-day or 60-day ***:Pancreatoduodenectomy can safely be performed in high-volume centers with very low *** surgeon’s role should be careful patient selection,intensive preoperative investigations,use of a team approach,and an unbiased discussion at a multidisciplinary meeting to optimize the outcome in these patients.

关键词： pancreatoduodenectomy multidisciplinary vascular resection

Light-stabilized FHA2 suppresses miRNA biogenesis through interactions with DCL1 and HYL1

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Molecular Plant 2021年第4期14卷 647-663页

作者： Seung jun Park Suk Won choi Gu Min Kim Christian Moller Hyun-Sook Pai Seong Wook Yang Department of Systems Biology College of Life Science and BiotechnologyYonsei UniversitySeoul 120749Korea EDepartment of Systems Biology Institute of Life Science and BiotechnologyYonsei UniversitySeoul 120-749Korea Department of Plant and Environnental Sciences Faculty of ScienceUniversity of CopenhagenThorvaldsensvei 40DK-1871 FrederiksbergCopenhagenDenmark Pohang University of Science and Technology(POSTECH) 77 Cheongam-RoNam-GuPohangGyeongbuk37673.Korea These authors contributed equally to this article.

The precise regulation of microRNA(miRNA)biogenesis is crucial for plant development,which requires core microprocessors and many fine tuners to coordinate their miRNA processing activity/specificity in fluctuating cellular *** de-etiolation,light triggers a dramatic accumulation of core microprocessors and primary miRNAs(pri-miRNAs)but decreases pri-miRNA processing activity,resulting in relatively constant miRNA *** mechanisms underlying these seemingly contradictory regulatory changes remain *** this study,we identified forkhead-associated domain 2(FHA2)as a light-stabilized suppressor of miRNA *** found that FHA2 deficiency increased the level of mature miRNAs,accompanied by a reduction in pri-miRNAs and target *** assays showed that FHA2 associates with the core microprocessors DCL1,HYL1,and SE,forming a complex to suppress their pri-miRNA processing *** analyses revealed that FHA2 promotes HYL1 binding but inhibits the binding of DCL1-PAZ-RNase-RNA-binding domains(DCL1-PRR)to miRNAs,whereas FHA2 does not directly bind to these ***,we found that FHA2 protein is unstable in the dark but stabilized by light during ***,disruption of FH A led to defects in light-triggered changes in miRNA expression and reduced the survival rate of deetiolated seedlings after prolonged light ***,these data suggest that FHA2 is a novel light-stabilized suppressor of miRNA biogenesis and plays a role in fine-tuning miRNA processing during de-etiolation.

关键词： miRNA biogenesis Suppressor of the microprocessor miRNA-biogenetic inconsistency