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Frontiers of Materials Science 2017年第4期11卷 395-409页

作者： Mathew JOY SrividhyaJ. IYENGAR jui CHAKRABORTY Swapankumar GHOSH Project Management Division CSIR-Central Glass & Ceramic Research Institute Kolkata-700032 India Bioceramics & Coating Division CSIR-Central Glass & Ceramic Research Institute Kolkata-700032 India

The present work demonstrates the possibilities of hydrothermal trans- formation of Zn-AI layered double hydroxide （LDH） nanostructure by varying the synthetic conditions. The manipulation in washing step before hydrothermal treatment allows control over crystal morphologies, size and stability of their aqueous solutions. We examined the crystal growth process in the presence and the absence of extra ions during hydrothermal treatment and its dependence on the drug （diclofenac sodium （Dic- Na）） loading and release processes. Hexagonal plate-like crystals show sustained release with -90% of the drug from the matrix in a week, suggesting the applicability of LDH nanohybrids in sustained drug delivery systems. The fits to the release kinetics data indicated the drug release as a diffusion-controlled release process. LDH with rod-like morphology shows excellent colloidal stability in aqueous suspension, as studied by photon correlation spectroscopy.

关键词： layered double hydroxide crystal morphology hydrothermal treatment drug loading

Reversible ischemia on treadmill exercise in left main coronary artery vasospasm

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Chinese Medical Journal 2011年第24期124卷 4364-4367页

作者： HUNG Ming-yow CHANG Nen-chung HUNG Ming-jui Division of Cardiology Department of Internal Medicine Shuang Ho Hospital Taipei Medical University Taipei 235 Taiwan China Department of Internal Medicine School of Medicine College of Medicine Taipei Medical University Taipei 110 Taiwan China Division of Cardiology Department of Internal Medicine Taipei Medical University Hospital Taipei 110 Taiwan China Department of Cardiology Chang Gung Memorial Hospital Keelung Chang Gung University College of Medicine Keelung city 20401 Taiwan China

Coronary vasospasm of the left main coronary artery （LMCA） is a rare condition with potentially devastating consequences. We present 2 patients with LMCA vasospasm-related angina, the first being a 46-year-old woman and the second a 51-year-old woman. Both of them developed ST-segment ischemic changes on treadmill exercise tests. Coronary angiography showed spontaneous LMCA vasospasm in one patient and methylergonovine-induced LMCA vasospasm in the other patient. Follow-up treadmill exercise tests revealed no exercise-induced ischemia after calcium antagonist monotherapy. These cases demonstrate the importance of identifying LMCA vasospasm, as the treatment of choice varies in patients with angina pectoris. Reversible myocardial ischemia caused by LMCA vasospastic angina can be controlled by calcium antagonist monotherapy and detected by repeat non-invasive stress testing.

关键词： ischemia treadmill left main coronary artery coronary vasospasm

Applying ionic liquids as oil additives for gearboxes:Going beyond the state of the art by bridging the nano-scale and component level

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Friction 2023年第6期11卷 1057-1078页

作者： Azhaarudeen ANIFA MOHAMED FARUCK Philipp G.GRÜTZMACHER Chia-jui HSU Dominik DWORSCHAK Hsiu-Wei CHENG Markus VALTINER Kristof STAGEL Philipp MIKSOVSKY Apurba Ranjan SAHOO Aitor SAINZ MARTINEZ Katharina BICA-SCHRODER Michael WEIGAND Carsten GACHOT Institut für Konstruktionswissenschaften und Produktentwicklung(IKP) Tribology Research DivisionTU WienVienna1060Austria Institut für Angewandte Physik(IAP) Applied Interface Physics research groupTU WienVienna1040Austria Institut für Angewandte Synthesechemie(IAS) Sustainable Organic Synthesis and Catalysis research groupTU WienVienna1060Austria

Ionic liquids(ILs)have been used effectively in many applications for reducing problems related to friction and *** this work,the potential of ILs as an anti-wear and extreme pressure lubricant additive for high load-carrying gearbox applications such as helicopter transmissions has been *** halide-free ILs:P_(8881)(BuO)_(2)PO_(2)^(-)(1)and P_(8881)(MeO)_(2)PO_(2)^(-)(2),which are blended at 5 wt%each into a standard non-additivated FVA2 base oil(BO)are *** solid-liquid interface,friction and load-carrying capacity,and wear(scuffing)behavior are studied on the nano-,lab-,and component-scale,respectively,at a different range of temperature and loading conditions by using the atomic force microscopy(AFM),Schwing-Reib-Verschleiβ(SRV)friction tests,and Brugger tests,as well as forschungsstelle für zahnrader und getriebebau(FZG)back-to-back gear test *** AFM analysis shows nearly no change of adhesion over the full range of studied temperature for the IL blends compared to the ***,IL blends demonstrate a very stable coefficient of friction(COF)of around 0.16,which even decreases with increasing test temperatures ranging from 40 to 120℃.A clear reduction in COF up to 25%is achieved by adding only 5 wt%of the investigated Ils in the BO,and the Brugger tests also show a pronounced enhancement of load-carrying ***,on the component-scale,a significant improvement in gear scuffing performance has been observed for both used IL blends.A detailed characterization of the wear tracks from the SRV friction tests via the transmission electron microscopy(TEM)revealed the formation of a phosphate(P-O)-based amorphous tribo-chemical layer of about 20 nm ***,this work may present an approach for Ils to be used as an additive in conventional lubricants due to their ability to enhance the lubrication properties,making them an alternative lubricant solution for high load-carrying gearbox applications.

关键词： ionic liquids(ILs) additives gears scuffing friction load-carrying capacity

FinTech in Taiwan:a case study of a Bank’s strategic planning for an investment in a FinTech company

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Financial Innovation 2016年第1期2卷 186-201页

作者： jui-Long Hung Binjie Luo Boise State University BoiseUSA Agricultural Bank of China SichuanChina

Introduction:Since 2015 is the year of FinTech in Taiwan,it is worth investigating the challenges that emerged when banks were encouraged to invest in FinTech companies for *** study aims to identify the strategic considerations in the process of searching for FinTech investment *** description:This study used a case study investigation of a top-5 bank in *** major data sources include the meeting notes of the FinTech investment task force and interviews with the team ***-opetition theory was adopted as the theoretical framework and interview questions were derived from the PARTS strategies in co-petition *** results relate to:(1)the strategic goals of FinTech investment,(2)the added value from FinTech companies,(3)criteria in selecting candidates in the same FinTech area,(4)choosing to work as either a cooperator or a competitor,and(5)barriers from policies and *** and evaluation:This study has several findings:(1)regulations and policies shape FinTech’s development;(2)banks,technology companies,and customers are not“FinTech ready;”(3)Compare top-down with bottom up strategies;(4)banks and FinTech companies have complex relationships;(5)it is unlikely that Taiwan will produce FinTech disruptors in the near ***:The findings and discussion can benefit researchers and administrators in finance-related *** studies are desired to observe long-term development in terms of how companies collaborate or compete in specific FinTech areas.

关键词： FinTech Taiwan FinTech Industry Investment in FinTech Bank 3.0 Taiwan bank industry Co-opetition Theory PARTS

Correlation analysis and multiple regression formulas of refractive errors and ocular components

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International Journal of Ophthalmology(English edition) 2019年第5期12卷 858-861页

作者： Chao-Kai Chang jui-Teng Lin Yong Zhang Nobel Eye Institute New Vision Inc. Gong-Rui Medical Technology Department of Ophthalmology Shandong Provincial HospitalShandong University

The multiple regression formulas and correlation of ocular components with refractive errors are presented by Gaussian optics. The refractive error changing rate for the cornea and lens power, the axial length, anterior chamber depth(ACD) and vitreous chamber depth(VCD) are calculated, including nonlinear terms for more accurate rate functions than the linear theory. Our theory, consistent with the empirical data, shows that the Pearson correlation coefficients for spherical equivalent(SE) and ocular components are highest for SE with axial length, ACD and VCD and weakest for corneal power, lens power and lens thickness. Moreover, our regression formulas show the asymmetric feature of the correlation that the axial length, ACD and VCD are more strongly correlated(with higher negative regression constants) with refractive errors in eyes with hyperopia than in eyes with myopia, particularly for severe hyperopia.

关键词： human eye ocular components refractive errors regression formulas correlation

Human eye ocular component analysis for refractive state and refractive surgery

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International Journal of Ophthalmology(English edition) 2017年第7期10卷 1076-1080页

作者： Chao-Kai Chang jui-Teng Lin Yong Zhang Nobel Eye Institute New Vision Inc Gong-Rui Medical Technology Department of Ophthalmology Shandong Provincial Hospital

AIM： To analyze the clinical factors influencing the human vision corrections via the changing of ocular components of human eye in various applications; and to analyze refractive state via a new effective axial ***： An effective eye model was introduced by the ocular components of human eye including refractive indexes, surface radius（r1, r2, R1, R2） and thickness（t, T） of the cornea and lens, the anterior chamber depth（S1） and the vitreous length（S2）. Gaussian optics was used to calculate the change rate of refractive error per unit amount of ocular components of a human eye（the rate function M）. A new criterion of myopia was presented via an effective axial ***： For typical corneal and lens power of 42 and 21.9 diopters, the rate function Mj（j=1 to 6） were calculated for a 1% change of r1, r2, R1, R2, t, T（in diopters） M1=＋0.485, M2=-0.063, M3=＋0.053, M4=＋0.091, M5=＋0.012, and M6=-0.021 diopters. For 1.0 mm increase of S1 and S2, the rate functions were M7=＋1.35, and M8=-2.67 diopter/mm, respectively. These rate functions were used to analyze the clinical outcomes in various applications including laser in situ keratomileusis surgery, corneal cross linking procedure, femtosecond laser surgery and scleral ablation for ***： Using Gaussian optics, analytic formulas are presented for the change of refractive power due to various ocular parameter changes. These formulas provide useful clinical guidance in refractive surgery and other related procedures.

关键词： Gaussian optics human eye ocular components refractive errors vision correction laser in situ keratomileusis corneal collagen crosslinking

Does laser surface texturing really have a negative impact on the fatigue lifetime of mechanical components?

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Friction 2021年第6期9卷 1766-1775页

作者： Chia-jui HSU Andreas STRATMANN Simon MEDINA Georg JACOBS Frank MÜCKLICH Carsten GACHOT Institute for Engineering Design and Product Development TU WienLehárgasse 6Campus GetreidemarktVienna 1060Austria Chair of Functional Materials Saarland UniversityCampus D3.3Saarbrücken 66123Germany AC2T Research GmbH Viktor-Kaplan-Straße 2/CWiener Neustadt 2700Austria Institute for Machine Elements and Systems Engineering RWTH AachenSchinkelstraße 10Aachen 52062Germany

Laser surface texturing(LST)has been proven to improve the tribological performance of machine *** micro-scale patterns manufactured by LST may act as lubricant reservoirs,thus supplying oil when encountering insufficient ***,not many studies have investigated the use of LST in the boundary lubrication regime,likely due to concerns of higher contact stresses that can occur with the increasing surface *** study aims to examine the influence of LST on the fatigue lifetime of thrust rolling bearings under boundary lubrication.A series of periodic patterns were produced on the thrust rolling bearings,using two geometrically different designs,namely cross and dimple *** oil ISO VG 100 mixed with 0.05 wt%P of zinc dialkyldithiophosphate(ZDDP)was *** bearings with cross patterns reduce the wear loss by two orders of *** patterns not only retain lubricant in the textured pockets but also enhance the formation of an anti-wear *** tribofilm generation may be improved by the higher contact stresses that occur when using the textured ***,in contrast to the negative concerns,the ball bearings with cross patterns were instead found to increase the fatigue life by a factor of three.

关键词： thrust rolling bearing laser surface texturing direct laser interference patterning zinc dialkyldithiophosphate(ZDDP) tribofilm

Helicobacter pylori infection concomitant with metabolic syndrome further increase risk of colorectal adenomas

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World Journal of Gastroenterology 2010年第30期16卷 3841-3846页

作者： Ying-Lung Lin jui-Kun Chiang Shih-Min Lin Chih-En Tseng Department of Family Medicine Buddhist Tzu-Chi Dalin General Hospital Department of Biological Sciences University of Waikato Department of Anatomic Pathology Buddhist Dalin Tzu Chi General Hospital School of Medicine Buddhist Tzu Chi University

AIM: To investigate the association of colorectal adenomas with both Helicobacter pylori (H. pylori) infection and metabolic syndrome. METHODS: Using a cross-sectional hospital-based study, we analyzed physical examination data from 9311 healthy subjects with overnight physical examinations performed between January 2004 and December 2006. Examined data included gender, age, life style, anthropometric measurements, blood pressure, biochemical and hematological studies, H. pylori infection detected by esophagogastroduodenoscopy and biopsy urease tests, and colorectal adenomas detected with a complete total colonoscopy. RESULTS: The prevalence values for H. pylori infection, metabolic syndrome, and colorectal adenoma were39.2%, 18.7%, and 20.7%, respectively. Colorectal adenoma risk factors included male gender [odd ratio (OR): 2.005, 95% conf idence interval (CI): 1.740-2.310, P < 0.001], advanced age (OR: 1.046, 95% CI: 1.040-1.052, P < 0.001), smoking (OR: 1.377, 95% CI: 1.146-1.654, P = 0.001), increased body fat (OR: 1.016, 95% CI: 1.007-1.026, P = 0.001), higher white blood cell count (OR: 1.038, 95% CI: 1.005-1.073, P = 0.025), H. pylori infection (OR: 1.366, 95% CI: 1.230-1.517, P < 0.001), and metabolic syndrome (OR: 1.408, 95% CI: 1.231-1.610, P < 0.001). In addition, concomitant H. pylori infection with metabolic syndrome further increased the probability of colorectal adenomas. CONCLUSION: Our study revealed H. pylori infection with concomitant metabolic syndrome might further increase the risk of colorectal adenomas.

关键词： Biopsy urease test Colorectal adenoma Colorectal cancer Helicobacter pylori Metabolic syndrome

Oxaliplatin-induced severe anaphylactic reactions in metastatic colorectal cancer: Case series analysis

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World Journal of Gastroenterology 2012年第38期18卷 5427-5433页

作者： jui-Ho Wang Tai-Ming King Min-Chi Chang Chao-Wen Hsu Division of Colorectal Surgery Department of Surgery Kaohsiung Veteran General Hospital Kaohsiung 81346 Taiwan China Faculty of Medicine School of Medicine National Yang-Ming UniversityTaipei 112 Taiwan China

AIM: To investigate oxaliplatin-induced severe anaphylactic reactions (SAR) in metastatic colorectal cancer in a retrospective case series analysis and to conduct a systemic literature review. METHODS: During a 6-year period from 2006 to 2011 at Kaohsiung Veterans General Hospital, a total of 412 patients exposed to oxaliplatin-related chemotherapy were retrospectively reviewed. Relevant Englishlanguage studies regarding life-threatening SAR following oxaliplatin were also reviewed in MEDLINE and PubMed search. RESULTS: Eight patients (1.9%, 8 of 412 cases) were identified. Seven patients were successful resuscitated without any sequelae and one patient expired. We changed the chemotherapy regimen in five patients and rechallenged oxaliplatin use in patient 3. Twenty-three relevant English-language studies with 66 patients were reported. Patients received a median of 10 cycles of oxaliplatin (range, 2 to 29). Most common symptoms were respiratory distress (60%), fever (55%), and hypotension (54%). Three fatal events were reported (4.5%). Eleven patients (16%) of the 66 cases were rechallenged by oxaliplatin. CONCLUSION: SAR must be considered in patients receiving oxaliplatin-related chemotherapy, especially in heavily pretreated patients. Further studies on the mechanism, predictors, preventive methods and management of oxaliplatin-related SAR are recommended.

关键词：奥沙利铂结直肠癌转移性过敏反应病例 PubMed 过敏性反应 SAR

Hepatocellular carcinoma diagnosis and treatment: An overview

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Liver Research 2020年第4期4卷 159-160页

作者： Steven D.Colquhoun yu-jui Yvonne Wan Department of Surgery University of California DavisSacramentoCAUSA Department of Pathology and Laboratory Medicine University of California DavisSacramentoCAUSA

For decades,chronic liver disease has remained an increasing global health *** vaccines and antiviral therapies,both hepatitis B and C remain enormous clinical *** steatosis has become a rapidly increasing worldwide concern that can be appropriately characterized as an evolving epidemic.1 Aroundtheworld alcohol consumption is onthe rise,while autoim-mune conditions and environmental toxins all continue contrib-uting to this seemingly universal health *** common denominator of chronic liver disease is progressive hepatic inflam-mation leading to fibrosis and cirrhosis.

关键词： diagnosis clinical treatment