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Two thin middle-crust low-velocity zones imaged in the Chuan-Dian region of southeastern Tibetan Plateau and their tectonic implications

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Science China Earth Sciences 2024年第5期67卷 1675-1686页

作者： Long LI Xin wang Guangbing hou Yuan ling Yinshuang AI Key Laboratory of Earth and Planetary Physics Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China Innovation Academy for Earth Science Chinese Academy of SciencesBeijing 100029China

Intracrustal low-velocity zones(LVZs)indicate a mechanically weak crust and are widely observed in the southeast margin of the Tibetan ***,their spatial distributions and formation mechanisms remain *** investigate their distribution and detailed morphology of the LVZs in the southeastern Tibetan Plateau,here we used teleseismic events and continuous waveform data recorded by 40 broadband seismic stations newly deployed in the Sichuan-Yunnan region from December 2018 to October 2020.A total of 12,924 high-quality P-wave receiver functions and 5–40 s fundamental Rayleigh surface wave phase velocity dispersion curves from ambient noise cross-correlation functions were *** Swave velocity model at a depth interval of 0–100 km in the study area was inverted by using the trans-dimensional Markov chain Monte Carlo strategy to jointly invert the complementary data of the receiver function waveform and Rayleigh surface wave phase velocity *** results show that there are two separate LVZs(~3.5 km/s)surrounding the rigid Daliangshan subblock at crustal depths of approximately 30–40 km,providing new constraints on the geometry of the LVZs in our study *** two LVZs obtained in this study may represent the middle crustal flow channels,through which the material in the center of the Tibetan Plateau extrudes to its southeast *** by the rigid Sichuan Basin and the spindle-like Daliangshan subblock,the material continues to flow southward through the mechanically weak middle crustal channels surrounding the Daliangshan *** addition,the existence of thin LVZs in the middle crust plays an important role in understanding the decoupling between the upper and lower crust in the study *** also provides new constraint on the complex tectonic deformation process of the southeastern margin of the Tibetan Plateau caused by the collision and compression of the Indian and the Eurasian plates.

关键词： Southeastern Tibetan Plateau Joint inversion Intracrustal low-velocity zone Mid-crustal channel flow

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Regulation of cytokinin biosynthesis using PtRD26pro-IPT module improves drought tolerance through PtARR10-PtYUC4/5-mediated reactive oxygen species removal in Populus

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Journal of Integrative Plant Biology 2022年第3期64卷 771-786页

作者： hou-ling wang Qi Yang Shuya Tan Ting wang Yi Zhang Yanli Yang Weilun Yin Xinli Xia Hongwei Guo Zhonghai Li National Engineering Laboratory for Tree Breeding College of Biological Sciences and TechnologyBeijing Forestry UniversityBeijing100083 China Department of Biology Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education InstitutesSouthern University of Science and Technology(SUSTech)Shenzhen518055 China

Drought is a critical environmental factor which constrains plant survival and *** engineering provides a credible strategy to improve drought tolerance of ***,we generated transgenic poplar lines expressing the isopentenyl transferase gene(IPT)under the driver of Pt RD26 promoter(PtRD26 pro-IPT).Pt RD26 is a senescence and drought-inducible NAC transcription *** RD26 pro-IPT plants displayed multiple phenotypes,including improved growth and drought *** analysis revealed that auxin biosynthesis pathway was activated in the PtRD26 pro-IPT plants,leading to an increase in auxin *** analysis revealed that ARABIDOPSIS RESPONSE REGULATOR10(PtARR10),one of the type-B ARR transcription factors in the cytokinin pathway,was induced in PtRD26 pro-IPT plants and directly regulated the transcripts of YUCCA4(Pt YUC4)and YUCCA5(PtYUC5),two enzymes in the auxin biosynthesis *** of PtYUC4 enhanced drought tolerance,while simultaneous silencing of PtYUC4/5 evidently attenuated the drought tolerance of Pt RD26 pro-IPT ***,Pt YUC4/5 displayed a conserved thioredoxin reductase activity that is required for drought tolerance by deterring reactive oxygen species *** work reveals the molecular basis of cytokinin and auxin interactions in response to environmental stresses,and shed light on the improvement of drought tolerance without a growth penalty in trees by molecular breeding.

关键词： auxin cytokinin drought tolerance leaf senescence PtARR PtYUC ROS

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Verticillium dahliae Secretory Effector PevD1 Induces Leaf Senescence by Promoting ORE1-Mediated Ethylene Biosynthesis

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Molecular Plant 2021年第11期14卷 1901-1917页

作者： Yi Zhang Yuhan Gao hou-ling wang Chengcheng Kan Ze Li Xiufen Yang Weilun Yin Xinli Xia Hong Gil Nam Zhonghai Li Hongwei Guo Beijing Advanced Innovation Center for Tree Breeding by Molecular Design National Engineering Laboratory for Tree BreedingCollege of Biological Sciences and TechnologyBeijing Forestry UniversityBeijing 100083China The State Key Laboratory for Biology of Plant Disease and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Center for Plant Aging Research Institute for Basic ScienceDaegu 42988Republic of Korea New Biology Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguSouth Korea Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes Department of BiologySouthern University of Science and Technology(SUSTech)ShenzhenGuangdong 518055China

Leaf senescence,the final stage of leaf development,is influenced by numerous internal and environmental *** far,how biotic stresses such as pathogen infection regulate leaf senescence is ***,we found that the premature leaf senescence caused by a soil-borne vascular fungus Verticillium dahliae in Arabidopsis was impaired by the mutation of a protein elicitor from *** 1(PevD1).Constitutive or inducible overexpression of PevD1 accelerated Arabidopsis leaf senescence.A senescence-associated NAC transcription factor,ORE1,was targeted by ***1 interacted with and stabilized ORE1 protein by disrupting its interaction with the RING-type ubiquitin E3 ligase *** of ORE1 suppressed the premature senescence caused by overexpressing *** of ORE1 or PevD1 led to enhanced ethylene production,and ORE1 mediated PevD1-induced ethylene biosynthesis by directly binding to the ACS6 ***-of-function of ACSs suppressed ***-induced leaf senescence in ORE1-overexpressing ***,PevD1 also interacted with Gossypium hirsutum ORE1(GhORE1),and virus-induced gene silencing of GhORE1 delayed ***-triggered leaf senescence in cotton,indicative of the existence of a conserved mechanism in ***,our study demonstrates that *** induces leaf senescence by secreting the effector PevD1 to regulate the ORE1-ACS6 cascade,providing new insight into biotic stress-induced senescence in plants.

关键词： ACS6 ORE1 PevD1 Verticillium dahliae leaf senescence

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In vitro investigations on the effects of graphene and graphene oxide on polycaprolactone bone tissue engineering scaffolds

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Bio-Design and Manufacturing 2024年第5期7卷 651-669页

作者： Yanhao hou Weiguang wang Paulo Bartolo School of Engineering Faculty of Science and EngineeringThe University of ManchesterManchesterUK Singapore Centre for 3D Printing School of Mechanical and Aerospace EngineeringNanyang Technological UniversitySingaporeSingapore

Polycaprolactone(PCL)scaffolds that are produced through additive manufacturing are one of the most researched bone tissue engineering structures in the *** to the intrinsic limitations of PCL,carbon nanomaterials are often investigated to reinforce the PCL *** several studies that have been conducted on carbon nanomaterials,such as graphene(G)and graphene oxide(GO),certain challenges remain in terms of the precise design of the biological and nonbiological properties of the *** paper addresses this limitation by investigating both the nonbiological(element composition,surface,degradation,and thermal and mechanical properties)and biological characteristics of carbon nanomaterial-reinforced PCL scaffolds for bone tissue engineering *** showed that the incorporation of G and GO increased surface properties(reduced modulus and wettability),material crystallinity,crystallization temperature,and degradation ***,the variations in compressive modulus,strength,surface hardness,and cell metabolic activity strongly depended on the type of ***,a series of phenomenological models were developed based on experimental results to describe the variations of scaffold’s weight,fiber diameter,porosity,and mechanical properties as functions of degradation time and carbon nanomaterial *** results presented in this paper enable the design of three-dimensional(3D)bone scaffolds with tuned properties by adjusting the type and concentration of different functional fillers.

关键词： Additive manufacturing Bone tissue engineering Carbon nanomaterial Graphene Graphene oxide Scaffold

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Preparation of Laser Cladding Coating Undercooling Cu-based Alloy and Co on Non-equilibrium Solidification Structure

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Journal of Wuhan University of Technology(Materials Science) 2024年第2期39卷 463-472页

作者：田徐铭 CAO Shichao hou Kai hou Xiaopeng wang Hongfu 张煜 Department of Outpatient Xinzhou People’s HospitalXinzhou 034099China School of Mechanical Engineering North University of ChinaTaiyuan 030051China Department of Neurosurgery Xinzhou People’s HospitalXinzhou 034099China Department of Orthopedics Xinzhou People’s HospitalXinzhou 034099China

The effect of the gradient content of Co element on the solidification process of Cu-based alloy under deep under cooling conditions was *** non-equilibrium solidification structure of the under cooled alloy samples were *** is found that the rapidly solidified alloy has undergone twice grain refinement during the undercooling *** and significance of the maximum undercooling refinement structure of Cu60Ni35Co5 at T=253 K were ***-density defects were observed,such as dislocations,stacking faults networks,and twinning *** standard FCC diffraction pattern represents that it is still a single-phase *** on the metallographic diagram,EBSD and TEM data analysis,it is illustrated that the occurrence of grain refinement under high undercooling is due to stress induced *** addition,the laser cladding technology is used to coat Co-based alloy(Stellite12) coating on 304 stainless steel substrate;the microstructure of the coating cross-section was *** was found that the microstructure of the cross-section is presented as columnar crystals,planar crystals,and disordered growth direction,so that the coating has better hardness and wear *** electrochemical corrosion of the substrate and coating,it can be seen that the Co and Cr elements present in the coating are more likely to form a dense passivation film,which improved the corrosion resistance of the coating.

关键词： non-equilibrium solidification structure undercooling recrystallization laser cladding coating

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Tailored energy absorption for a novel auxetic honeycomb structure under large deformation

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Science China(Physics,Mechanics & Astronomy) 2024年第5期67卷 63-80页

作者： Xiuhui hou Bin wang Zichen Deng School of Mechanics Civil Engineering and ArchitectureNorthwestern Polytechnical UniversityXi'an 710129China MIIT Key Laboratory of Dynamics and Control of Complex Systems Northwestern Polytechnical UniversityXi'an 710072China School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentDalian University of TechnologyDalian 116024China

In comparison to conventional hexagonal honeycomb structures,auxetic metamaterials with re-entrant configurations have exhibited superior mechanical properties in terms of energy *** further enhance the energy absorption capacity of these materials,a novel re-entrant honeycomb configuration,named novel auxetic re-entrant honeycomb(NARH),is developed by incorporating“”-shaped cell walls into the conventional auxetic re-entrant honeycomb(ARH).Two analytical models for the plateau stress are formulated to consider the plastic deformation of NARH during quasi-static compression and the dynamic impact using the linear momentum ***-static compression tests on 3D printed NARH honeycomb specimens and finite element simulations are performed to verify the effectiveness of the theoretical *** exhibits higher plateau stresses compared with ARH during compression,which can be attributed to the presence of more plastic hinges formed in *** hinges,the embedded parts with inclined cell walls,not only improve stability by forming stable triangles during compression but also enhance the energy absorption capacity.A parametric study is conducted to analyze the effect of impact velocity,thickness,and incline angle of cell walls on *** simulations demonstrate higher sensitivity of the mechanical properties to impact velocity and cell wall *** ribs to the“”-shaped cell walls in NARH further reduces the initial peak force during dynamic crushing while maintaining high energy *** research provides valuable guidelines for the design of energy absorption metamaterials.

关键词： absorption walls shaped

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Multidimensional coupled structure-activity relationship models for replacement of SF_(6)

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High Voltage 2024年第2期9卷 484-494页

作者： Mi Zhang Hua hou Baoshan wang College of Chemistry and Molecular Sciences Wuhan UniversityWuhanChina

Computational screening of single gases to replace SF_(6)for electrical insulation has been challenged by the difficulty in combining various mutually exclusive properties especially for dielectric performance with liquefaction and environmental *** reveal the inherent correlations between dielectric strength(Er),boiling point(Tb),and global warming potential(GWP)of dielectric materials,a coupled structure-activity relationship(CSAR)model has been proposed for the first *** means of the generic descriptors,as deduced from the electrostatic potentials,and the specific descriptors,as introduced from the respective microscopic mechanisms,the complex interdependence between Er,Tb,and GWP of the insulation gases is quantitatively characterised by the 3-D coupling *** coupling mechanism for the right balance of properties is uncovered in terms of the first-principle *** CSAR model outperforms the previous SAR models in predicting Er,Tb,and GWP simultaneously in a self-consistent *** importantly,the concept of CSAR could be extended readily to any multidimensional macroscopic *** replacement compounds have been identified tentatively to be the promising candidates to replace SF_(6)using the CSAR model.

关键词： properties. dielectric insulation

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Bioinspired nanofluidic iontronics for brain-like computing

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Nano Research 2024年第2期17卷 503-514页

作者： Lejian Yu Xipeng Li Chunyi Luo Zhenkang Lei Yilan wang Yaqi hou Miao wang Xu hou State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Institute of Artificial Intelligence Xiamen UniversityXiamen 361005China Department of Physics Research Institute for Biomimetics and Soft MatterFujian Provincial Key Laboratory for Soft Functional Materials ResearchJiujiang Research InstituteCollege of Physical Science and TechnologyXiamen UniversityXiamen 361005China The Higher Educational Key Laboratory for Biomedical Engineering of Fujian Province Department of BiomaterialsResearch Center of Biomedical Engineering of XiamenCollege of MaterialsXiamen UniversityXiamen 361005China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen 361005China Binzhou Institute of Technology Binzhou 256600China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361102China Engineering Research Center of Electrochemical Technologies of Ministry of Education Xiamen UniversityXiamen 361005China

The human brain performs computations via a highly interconnected network of *** inspiration from the information delivery and processing mechanism of the human brain in central nervous systems,bioinspired nanofluidic iontronics has been proposed and gradually engineered to overcome the limitations of the conventional electron-based von Neumann architecture,which shows the promising potential to enable efficient brain-like *** and tunable nanofluidic ion transport behaviors and spatial confinement show promising controllability of charge carriers,and a wide range of structural and chemical modification paves new ways for realizing brain-like ***,a comprehensive framework of mechanisms and design strategy is summarized to enable the rational design of nanofluidic systems and facilitate the further development of bioinspired nanofluidic *** review provides recent advances and prospects of the bioinspired nanofluidic iontronics,including ion-based brain computing,comprehension of intrinsic mechanisms,design of artificial nanochannels,and the latest artificial neuromorphic functions ***,the challenges and opportunities of bioinspired nanofluidic iontronics in the pioneering and interdisciplinary research fields are proposed,including brain–computer interfaces and artificial neurons.

关键词： human brain ion transport nanofluidics brain-like computing memristive effect

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PKC and PKA mediate LPS-induced release of CGRP in DRG neurons of neonatal rats

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Acta Pharmacologica Sinica 1999年第5期 87-88页

作者： hou ling-Fei, wang Xian(Institute of Vascular Medicine, Third Hospital, Beijing MedicalUniversity, Beijing 100083 , China)

Calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide, is produced in dorsal root ganglia (DRG) neurons, which extend nerves peripherally to different organs and centrally to the spinal *** have previously reported that plasma levels of CGRP are significantly elevated in rats after injection of lipopolysaccharide (LPS) in *** triggers CGRP release from capsaicin-sensitive sensory nerves in the isolated mesenteric arteial bed of the *** this work, we used the cultured DRG neurons of neonatal mrs to detemine whether or not LPS could trigger CGRP release and if it did so, what cellular signaling pathway was involved in the CGRP *** were disassociated from the DRG of 5- 7-d neonatal rat using

关键词： CGRP DRG PKC and PKA mediate LPS-induced release of CGRP in DRG neurons of neonatal rats PKA

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Multi-functional Hollow Structures for Intelligent Drug Delivery

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Chemical Research in Chinese Universities 2024年第3期40卷 394-412页

作者： hou Ping YANG Nailiang wang Dan State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190P.R.China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049P.R.China Key Laboratory of Biopharmaceutical Preparation and Delivery Chinese Academy of SciencesBeijing 100049P.R.China

Multi-fountional hollow structures have emerged as promising platforms for intelligent drug delivery due to their unique properties,such as high loading capacities and programmed drug *** particular,hollow multishell structures(HoMSs)with multilevel shell and space can regulate the molecular-level interaction between drugs and materials,so as to achieve the temporal-spatial order and sequential release of *** anisotropic hollow structures can control the drug diffusion process by inducing the macroscopic interface flow through autonomous movement,realizing the targeted drug transport and *** this paper,a key focus will be HoMSs with their temporal-ordered architectures and anisotropic hollow carriers with directional *** synthesis mechanisms,structure-property relationships,smartly programmed drug delivery and biomedical applications will be discussed,providing insights into designing next-generation intelligent drug carriers.

关键词： Hollow multishell structure Anisotropic hollow structure Intelligent drug carrier Temporal-spatial order Directional movement

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