Multi-functional Hollow Structures for Intelligent Drug Delivery
作者机构：State Key Laboratory of Biochemical EngineeringInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190P.R.China School of Chemical EngineeringUniversity of Chinese Academy of SciencesBeijing 100049P.R.China Key Laboratory of Biopharmaceutical Preparation and DeliveryChinese Academy of SciencesBeijing 100049P.R.China
出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)
年 卷 期：2024年第40卷第3期
页 面：394-412页
核心收录：
学科分类：1007[医学-药学(可授医学、理学学位)] 10[医学]
基 金：This work was supported by the National Natural Science Foundation of China(Nos.92163209,21821005 and 51932001) the Beijing Natural Science Foundation,China(No.JQ22004)
主 题：Hollow multishell structure Anisotropic hollow structure Intelligent drug carrier Temporal-spatial order Directional movement
摘 要：Multi-fountional hollow structures have emerged as promising platforms for intelligent drug delivery due to their unique properties,such as high loading capacities and programmed drug *** particular,hollow multishell structures(HoMSs)with multilevel shell and space can regulate the molecular-level interaction between drugs and materials,so as to achieve the temporal-spatial order and sequential release of *** anisotropic hollow structures can control the drug diffusion process by inducing the macroscopic interface flow through autonomous movement,realizing the targeted drug transport and *** this paper,a key focus will be HoMSs with their temporal-ordered architectures and anisotropic hollow carriers with directional *** synthesis mechanisms,structure-property relationships,smartly programmed drug delivery and biomedical applications will be discussed,providing insights into designing next-generation intelligent drug carriers.
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