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Effective Common Chinese Herbal Medicines Used in Treating Chronic Cholecystitis with Liver-Gallbladder Dampness-Heat Syndrome: A Review of Clinical Studies in the Past 10 Years

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World Journal of Traditional Chinese Medicine 2023年第1期9卷 8-20页

作者： Desmond Wei Kang Tee hon foong wong Centrefor Complementary and Alternative Medicine International Medical UniversityKuala LumpurMalaysia

The objective of the study is to identify the effective common Chinese herbal medicines used in treating chronic cholecystitis with liver-gallbladder dampness-heat syndrome(CCLGDHS) through reviewing relevant clinical studies published in the past 10 years. Data were collected from Science Direct and Chinese National Knowledge Infrastructure. Data screening was carried out for the abstracts and full texts of the data. The top 15 Chinese herbal medicines with the highest occurring frequency were selected, statistically analyzed, and classified by their medicinal properties, actions, and indications according to the Chinese Pharmacopoeia 2015 edition. The top 15 effective common Chinese herbal medicines comprise Chai Hu, Huang Qin, Jin Qian Cao, Bai Shao, Yin Chen, Yu Jin, Chuan Lian Zi, Yan Hu Suo, Zhi Shi, Ban Xia, Bai Zhu, Pu Gong Ying, Gan Cao, Zhi Zi, and Qing Pi. The predominant natures were cold, cool, and warm. This combination can clear stagnant heat, warm Yang, and regulate Qi dynamics. In addition, bitter, pungent, and sweet were the predominant flavors. They can clear dampness-heat, regulate Qi dynamics to relieve cramps and pain, as well as tonify the deficiency. Along with entering the liver and gallbladder meridians, these herbal medicines also entered the spleen, stomach, and lung meridians to prevent potential disease transmission. The combinatorial medicinal actions of the effective common Chinese herbal medicine highlight the importance of the holistic concept of traditional Chinese medicine when treating CCLGDHS. In addition, the inclusion of activating blood to promote blood circulation, relieving cramps and alleviating pain, and tonifying the spleen and stomach represents a new finding in the treatment principle for CCLGDHS.

关键词： Chronic cholecystitis common Chinese herbal medicines liver-gallbladder dampness-heat syndrome traditional Chinese medicine treatment

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Cupping,the Past and Present Application

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Chinese Medicine and Culture 2018年第3期1卷 121-126页

作者： Xun Lin hon foong wong Shih Chau Ng International Education College Shanghai University of Traditional Chinese MedicineChina Department of Chinese Medicine Centre for Complementary and Alternative MedicineInternational Medical UniversityMalaysia

Cupping is a therapy in which a cup is applied to the skin surface to cause local congestion through negative *** has a long history in many places such as China,Greece,Egypt,and the Middle *** ancient Chinese used animal horns as their cupping instrument,whereas in modern days there are a wide variety of choices ranging from bamboo cup to glass *** is simple,inexpensive and yet has wide *** has shown that it can promote blood circulation,stimulate nerve and muscle *** terms of application methods,fire cupping,liquid cupping and vaccum cupping were *** five application techniques(flashing,retaining,moving,needle retention and bleeding)and precautions of cupping are also discussed in ***,pathological reactions observed during the cupping process can be used to support Chinese Medicine diagnosis.

关键词： Application cupping history

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Traditional Chinese Medicine in Malaysia:A Brief Historical Overview of the Interactions between China and Malay Peninsula

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Chinese Medicine and Culture 2018年第2期1卷 60-63页

作者： Wen Tien Tan hon foong wong Shih Chau Ng Si Woei Goh Jun Liu Bao Ling Hoo Chyong En Chai Xun Lin Department of Golden Cabinet International Education CollegeShanghai University of Traditional Chinese MedicineShanghaiChina Department of Chinese Medicine Centre for Complementary and Alternative MedicineInternational Medical UniversityKuala LumpurMalaysia

Chinese Medicine was introduced to the Malay Peninsula during the colonial era circa 18th to 19th *** British imported Chinese immigrants mainly for tin *** early Chinese settlers had brought with them the knowledge of Traditional Chinese Medicine(TCM)to *** time goes by,TCM becomes one of the popular traditional medicines that are accepted by other *** has thus contributed to the welfare of *** 2016,a Traditional and Complementary Medicine(T and CM)Act was passed by the Malaysia *** is one of the T and CM practices that fall under the *** services are now offered in Malaysia’s public hospitals in addition to private *** article aims to provide a brief overview on the development of TCM in the precolonial and postindependent Malaysia.

关键词： Development history Malaysia Traditional Chinese Medicine

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Traditional Chinese Medicine in Malaysia: A Brief Historical Overview of Laws and Regulations

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Chinese Medicine and Culture 2019年第3期2卷 162-165页

作者： hon foong wong Shih Chau Ng Wen Tien Tan Huiying Wang Xun Lin Si Woei Goh Bao Ling Hoo Chyong En Chai Jun Liu International Education College Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Chinese Medicine Centre for Complementary and Alternative MedicineInternational Medical UniversityKuala LumpurMalaysia

Although traditional Chinese medicine(TCM)has been a part of the Malaya and the Malaysia people’s method of maintaining health and well-being for many centuries,it was never been enrolled in the public health-care ***,the rising cost of Western drugs and the increasing number of people frequenting TCM has driven the government to search for cheaper options and to look into its safe *** 1992,the government mandated all TCM herbal products to be registered with the National Pharmaceutical Control *** TCM products sold in Malaysia are now Good Manufacturing Practice *** government has also established a Traditional and Complementary Medicine Division within the Ministry of *** 2008 and 2014,a traditional and complementary medicine unit was set up in major hospitals in all *** is one of the main services offered by the *** 2016,the government enacted the Traditional and Complementary Medicine Act to regulate the TCM ***,a 10-vear blueprint has been drawn to support the development of all traditional and complementary medicines in *** article aims to provide a brief overview on the regulatory development of TCM in Malaysia.

关键词： Development of traditional Chinese medicine historical overview laws and regulations Malaysia Traditional Chinese medicine

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Traditional Chinese Medicine in Malaysia: A Brief Historical Overview of the Institutions

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Chinese Medicine and Culture 2019年第1期2卷 15-18页

作者： Shih Chau Ng hon foong wong Wen Tien Tan Jun Liu Huiying Wang Xun Lin Si Woei Goh Bao Ling Hoo Chyong En Chai International Education College Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Chinese Medicine Centre for Complementary and Alternative MedicineInternational Medical UniversityKuala LumpurMalaysia

Traditional Chinese Medicine(TCM)in British Malaya developed concurrently with the influx of Chinese *** cater for tins growing community,Chinese medical halls which sell Chinese herbs were established in major *** and various TCM treatments were also offered by contract TCM practitioners in some of these medical *** the needs for TCM services continued to grow,dedicated TCM institutions were set up *** establishment of these institutions marked the beginning of professional TCM services in the history of Malaysia.

关键词： Development history Malaysia medical institutions Traditional Chinese Medicine

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Quantum Realities and Observer-Dependent Universes: An Advanced Observer Model

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Journal of Quantum Information Science 2024年第3期14卷 69-121页

作者： Joseph hon Cheung wong Department of Computing The Hong Kong Polytechnic University Hung Hom Kowloon Hong Kong China

This paper presents a novel observer model that integrates quantum mechanics, relativity, idealism, and the simulation hypothesis to explain the quantum nature of the universe. The model posits a central server transmitting multi-media frames to create observer-dependent realities. Key aspects include deriving frame rates, defining quantum reality, and establishing hierarchical observer structures. The model’s impact on quantum information theory and philosophical interpretations of reality are examined, with detailed discussions on information loss and recursive frame transmission in the appendices.

关键词： Quantum Mechanics Observer Model Frame Rates Quantum Reality Hierarchical Observers Information Theory Simulation Hypothesis Recursive Frame Transmission Information Loss

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Thermal pyrolysis conversion of methane to hydrogen(H_(2)):A review on process parameters,reaction kinetics and techno-economic analysis

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Chinese Chemical Letters 2024年第8期35卷 62-73页

作者： Yi Herng Chan Zhe Phak Chan Serene Sow Mun Lock Chung Loong Yiin Shin Ying foong Mee Kee wong Muhammad Anwar Ishak Ven Chian Quek Shengbo Ge Su Shiung Lam PETRONAS Research Sdn.Bhd.(PRSB) Kawasan Institusi BangiLot 3288&3289Off Jalan Ayer ItamKajang 43000Malaysia PETRONAS Carbon Capture&Storage(CCS)Enterprise PETRONAS Twin TowersKuala Lumpur City CentreKuala Lumpur 50088Malaysia CO_(2)Research Center(CO2RES) Department of Chemical EngineeringUniversiti Teknologi PETRONASSeri Iskandar 32610Malaysia Department of Chemical Engineering and Energy Sustainability Faculty of EngineeringUniversiti Malaysia Sarawak(UNIMAS)Kota Samarahan 94300Malaysia Institute of Sustainable and Renewable Energy(ISuRE) Universiti Malaysia Sarawak(UNIMAS)Kota Samarahan 94300Malaysia Higher Institution Centre of Excellence(HICoE) Institute of Tropical Aquaculture and Fisheries(AKUATROP)Universiti Malaysia TerengganuKuala Nerus 21030Malaysia Co-Innovation Center of Efficient Processing and Utilization of Forest Resources College of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037China Center for Global Health Research(CGHR) Saveetha Medical CollegeSaveetha Institute of Medical and Technical Sciences(SIMATS)Saveetha UniversityChennai 602105India

Hydrogen(H_(2))is a promising renewable energy which finds wide applications as the world gears toward low-carbon ***,current H_(2) production via steam methane reforming of natural gas or gasification of coal are laden with high CO_(2) ***,methane(CH_(4))pyrolysis has emerged as a potential technology to generate low-carbon H_(2) and solid *** this review,the current state-of-art and recent progress of H_(2) production from CH_(4) pyrolysis are reviewed in *** such as funda-mental mechanism and chemistry involved,effect of process parameters on the conversion efficiency and reaction kinetics for various reaction media and catalysts are elucidated and critically ***-ature,among other factors,plays the most critical influence on the methane pyrolysis *** metal/salt could lower the operating temperature of methane pyrolysis to1000℃.Based on the reaction kinetics,metal-based cata-lysts were more efficient in lowering the activation energy of the reaction to 29.5-88 kJ/mol from that of uncatalyzed reaction(147-420.7 kJ/mol).Besides,the current techno-economic performance of the pro-cess reveals that the levelized cost of H_(2) is directly influenced by the sales price of carbon(by-product)generated,which could offset the overall ***,the main challenges of reactor design for efficient product separation and retrieval,as well as catalyst deactivation/poisoning need to be debottlenecked.

关键词： Pyrolysis Methane Hydrogen Reaction kinetics Techno-economic analysis

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Neighboring effect in single-atom catalysts for the electrochemical carbon dioxide reduction reaction

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eScience 2024年第1期4卷 1-16页

作者： hon Ho wong Mingzi Sun Tong Wu Cheuk Hei Chan Lu Lu Qiuyang Lu Baian Chen Bolong Huang Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARChina Research Centre for Carbon-Strategic Catalysis The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARChina

Although single-atom catalysts(SACs)have attracted enormous attention for their applications in the electrochemical reduction of CO_(2)(CO_(2)RR)due to their extraordinary catalytic activity and well-defined active centers,neighboring effects and their influence on the electrochemical performance of SACs have not been well *** this review,we present a summary of the neighboring effects on SACs for the CO_(2)RR process,where the surrounding atoms not only induce electronic modulation of the metal atom but also participate in the CO_(2)*** theoretical and experimental studies have pointed out that the neighboring sites of the anchored metal center can provide second active/adsorption locations during the catalytic process,enhancing CO_(2)RR performance *** review supplies advanced insights into the significant roles and impacts of neighboring effects on the catalytic process,which also benefit the development of advanced SACs to achieve efficient electrocatalysis.

关键词： Carbon dioxide reduction Neighboring effect Atomic catalysts Electronic modulations Active sites

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Immunoregulatory and Anti-cancer Activities of Combination Treatment of Novel Four-Herb Formula and Doxorubicin in 4T1-Breast Cancer Bearing Mice

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Chinese Journal of Integrative Medicine 2024年第4期30卷 311-321页

作者： Lea Ling-Yu Kan Ben Chung-Lap Chan Grace Gar-Lee Yue LI Pei-ting Sharon Sze-Man hon HUANG Dan-qi Miranda Sin-Man Tsang Clara Bik-San Lau Ping-Chung Leung Chun-Kwok wong Institute of Chinese Medicine The Chinese University of Hong KongHong Kong SARChina State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants The Chinese University of Hong KongHong KongChina Department of Chemical Pathology The Chinese University of Hong KongHong Kong SARChina China-Australia International Research Centre for Chinese Medicine School of Health and Biomedical SciencesSTEM CollegeRMIT UniversityBundooraVictoriaAustralia Li Dak Sum Yip Yio Chin R&D Centre for Chinese Medicine The Chinese University of Hong Kong SARHong KongChina

Objective To investigate the in vivo immunomodulatory and anti-tumor mechanisms of the combined treatment of novel Four-Herb formula(4HF)and doxorubicin in triple-negative breast cancer(TNBC).Methods Murine-derived triple-negative mammary carcinoma cell line,4T1 cells,was cultured and inoculated into mouse mammary ***-six mice were randomly assigned into 6 groups(n=11 in ench):naive,control,LD 4HF(low dose 4HF),HD 4HF(high dose 4HF),LD 4HF+D(low dose and doxorubicin),and D(doxorubicin).Apart from the naive group,each mouse received subcutaneous inoculation with 5×10^(5)4T1 cells resuspended in 100µL of normal saline in the mammary fat *** from the day of tumor cell inoculation,tumors were grown for 6 *** LD and HD groups received daily oral gavage of 658 and 2,630 mg/kg 4HF,*** LD 4HF+D group received daily oral gavage of 658 mg/kg 4HF and weekly intraperitoneal injection of doxorubicin(5 mg/kg).The D group received weekly intraperitoneal injections of doxorubicin(5 mg/kg).The treatment naive mice received daily oral gavage of 0.2 mL double distilled water and 0.1 mL normal saline via intraperitoneal injection once a *** control group received daily oral gavage of 0.2 mL double-distilled *** treatment period was 30 *** the end of treatment,mice organs were harvested to analyze immunological activities via immunophenotyping,gene and multiplex analysis,histological staining,and gut microbiota *** Mice treated with the combination of 4HF and doxorubicin resulted in significantly reduced tumor and spleen burdens(P<0.05),altered the hypoxia and overall immune lymphocyte landscape,and manipulated gut microbiota to favor the anti-tumor immunological ***,immunosuppressive genes,cytokines,and chemokines such as C-C motif chemokine 2 and interleukin-10 of tumors were significantly downregulated(P<0.05).4HF-doxorubicin combination treatment demonstrated synergetic activities and was most effective

关键词： adjunctivetherapy breast cancer cytokines Chinese medicine tumor microenvironment

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The“Ukiyo”of Moxibustion Reflected in the Ukiyo-e

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Chinese Medicine and Culture 2024年第3期7卷 213-221页

作者： JIANG Shan hong foong wong(Translated) School of Medical Humanities and Social Sciences Peking Union Medical CollegeBeijing 100730China International Research Center for Japanese Studies Kyoto 610-1192Japan 不详

Ukiyo-e(浮世絵)was a genre of popular art during the Edo and Meiji periods in ***,which was originally introduced from China,was also in its heyday and became one of the popular topics for ukiyo-e artists at that *** the images as historical evidence perspective,this article focuses on the moxibustion used in daily life in Japan depicted in the ukiyo-e *** the perspective of acu-moxa therapy,one may identify some specific issues in the acupoint selection,leading to the discovery of special application of moxibustion used by the group of yūjo(遊女)at that *** article concludes by exploring gender issues in ukiyo-e arts and the implications of punishment attached to moxibustion treatment.

关键词： Moxibustion Ukiyo-e(浮世絵) Edo period Utagawa Kunisada(歌川国貞)

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