检索结果-南通市图书馆

Novel interface regulation of Sn1.0Ag0.5Cu composite solders reinforced with modified ZrO_(2):Microstructure and mechanical properties

引用

Journal of Materials Science & Technology 2022年第30期125卷 157-170页

作者： Fupeng Huo Zhi Jin Duy Le Han Jiahui Li Keke Zhang hiroshi nishikawa Joining and Welding Research Institute Osaka UniversityIbarakiOsaka 565-0047Japan Graduate School of Engineering Osaka UniversitySuitaOsaka 565-0871Japan School of Materials Science and Engineering Henan University of Science and TechnologyLuoyang 471023China Department of Welding Engineering and Metals Technology School of Mechanical EngineeringHanoi University of Science and TechnologyNo.1 Dai Co VietHai Ba TrungHanoiViet Nam

With the trends of miniaturization and high density of electronic packaging,there has been an urgent demand to open up lead-free solders with high strength and *** this study,a ZrO_(2)-reinforced Sn1.0Ag0.5Cu composite solder was ***,surface modification on ZrO_(2) was conducted with ball milling-pyrolysis ***,NiO modified ZrO_(2)(NiO/ZrO_(2))was added to the solder matrix with ultrasonic *** morphology and interface of NiO/ZrO_(2) were ***,the microstructure,interface and mechanical properties of the composite solders were systematically *** results showed that NiO nanoparticles were evenly adhered to the ZrO_(2) surface,and the interface relationship between them was semi-coherent and ***,an appropriate addition of NiO/ZrO_(2) could refine the microstructure of composite *** refinement mechanism was systematically ***,a micro-mechanical lock and non-micropored clean interface was formed between NiO/ZrO_(2) and the solder *** Sn/NiO/ZrO_(2) interface system based on mutual solid solution was ingeniously *** ultimate tensile strength and elongation were increased synergistically,and the fracture mechanism transformed from a ductile−brittle mixed fracture mode to a ductile fracture ***,a lead-free solder with high strength and ductility was obtained.

关键词： SnAgCu composite solder ZrO_(2)nanoparticles Refinement mechanism Surface modification Interface Reinforcements

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of elements Ni and Co on morphology and type of IMC at Sn-3Ag-0.5Cu solder joint interface

引用

Journal of Harbin Institute of Technology(New Series) 2009年第5期16卷 648-651页

作者：孟工戈 TAKEMOTO Tadashi nishikawa hiroshi School of Material Science & Engineering Harbin University of Science and Technology Joining and Welding Research Institute Osaka University

The intermetallic compound (IMC) is hard and brittle,and its forming and growth at soldering joint interface is an important issue in joint *** data obtained by digital optical electronic microscope indicate that the addition of element Co changes the IMC morphology from ball-like and bar-like to distinct and sharp in crest lines and *** addition of elements Ni and Co in Sn-3Ag-0.5Cu solder promotes the nucleation and makes the IMC size *** electron probe microanalysis (EPMA) determines the chemical compositions and confirms that the IMC is changed into the (Cu,Co,Ni)6Sn5+(Cu,Co,Ni)3Sn4 mixed type from the type of Cu6Sn5 with the elements Ni and Co in the solder.

关键词：钴元素镍元素 Sn5 类型形态界面焊点金属间化合物

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Stage at diagnosis of colorectal cancer through diagnostic route:Who should be screened?

引用

World Journal of Gastroenterology 2024年第10期30卷 1368-1376页

作者： Nobukazu Agatsuma Takahiro Utsumi Yoshitaka nishikawa Takahiro Horimatsu Takeshi Seta Yukitaka Yamashita Yukari Tanaka Takahiro Inoue Yuki Nakanishi Takahiro Shimizu Mikako Ohno Akane Fukushima Takeo Nakayama hiroshi Seno Department of Gastroenterology and Hepatology Kyoto University Graduate School of MedicineKyoto 606-8507Japan Department of Gastroenterology and Hepatology Japanese Red Cross Wakayama Medical CenterWakayama 640-8558Japan Department of Health Informatics Kyoto University School of Public HealthKyoto 606-8501Japan Institute for Advancement of Clinical and Translational Science(iACT) Kyoto University HospitalKyoto 606-8507Japan Medical Support Section Medical Affairs DivisionKyoto University HospitalKyoto 606-8507Japan

BACKGROUND Colorectal cancer(CRC)is a global health concern,with advanced-stage diagnoses contributing to poor *** efficacy of CRC screening has been well-established;nevertheless,a significant proportion of patients remain unscreened,with>70%of cases diagnosed outside *** identifying specific subgroups for whom CRC screening should be particularly recommended is crucial owing to limited resources,the association between the diagnostic routes and identification of these subgroups has been less *** the Japanese cancer registry,the diagnostic routes for groups discovered outside of screening are primarily categorized into those with comorbidities found during hospital visits and those with CRC-related *** To clarify the stage at CRC diagnosis based on diagnostic *** We conducted a retrospective observational study using a cancer registry of patients with CRC between January 2016 and December 2019 at two *** diagnostic routes were primarily classified into three groups:Cancer screening,follow-up,and *** early-stage was defined as Stages 0 or *** and univariate logistic regressions were exploited to determine the odds of early-stage diagnosis in the symptomatic and cancer screening groups,referencing the follow-up *** adjusted covariates were age,sex,and tumor *** Of the 2083 patients,715(34.4%),1064(51.1%),and 304(14.6%)belonged to the follow-up,symptomatic,and cancer screening groups,*** the 2083 patients,CRCs diagnosed at an early stage were 57.3%(410 of 715),23.9%(254 of 1064),and 59.5%(181 of 304)in the follow-up,symptomatic,and cancer screening groups,*** symptomatic group exhibited a lower likelihood of early-stage diagnosis than the follow-up group[P<0.001,adjusted odds ratio(aOR),0.23;95%confidence interval(95%CI):0.19-0.29].The likelihood of diagnosis at an early stage was similar between the follow-up and cancer screening gro

关键词： Colorectal neoplasms Cancer registry Diagnostic route Cancer screening Stage at diagnosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Heat Input Energy to Anode for Hollow Cathode Arc

Heat Input Energy to Anode for Hollow Cathode Arc

引用

The Fourth International Conference on Physical and Numerical Simulation of Materials Processing (ICPNS’2004)

作者： hiroshi nishikawa Shinichiro Shobako Masashi Ohta Takayoshi Ohji Collaborative Research Center for Advanced Science and Technology Osaka University Yamadaoka 2-1 Suita Osaka 565-0871 Japan Department of Adaptive Machine Systems Graduate School of Engineering Osaka University Yamadaoka 2-1 Suita Osaka 565-0871 Japan Collaborative Research Center for Advanced Science and Technology Osaka University Yamadaoka 2-1 Suita Osaka 565-0871 Japan Department of Adaptive Machine Systems Graduate School of Engineering Osaka University Yamadaoka 2-1 Suita Osaka 565-0871 Japan Collaborative Research Center for Advanced Science and Technology Osaka University Yamadaoka 2-1 Suita Osaka 565-0871 Japan Department of Adaptive Machine Systems Graduate School of Engineering Osaka University Yamadaoka 2-1 Suita Osaka 565-0871 Japan Collaborative Research Center for Advanced Science and Technology Osaka University Yamadaoka 2-1 Suita Osaka 565-0871 Japan Department of Adaptive Machine Systems Graduate School of Engineering Osaka University Yamadaoka 2-1 Suita Osaka 565-0871 Japan

In order to elucidate whether Hollow Cathode Arc (HCA) can be used for a welding heat source in space, the investigations into fundamental characteristics of the HCA have been experimentally performed under low pressure conditions. The HCA method enables an arc discharge to ignite and maintain under low pressure conditions, where it is extremely difficult for the conventional GTA method to form an arc *** the previous paper, it has been shown that the melting process by the HCA is very sensitive to process parameters, such as gas flowrate and arc length, and a huge penetration has been formed under the condition that the arc length is long and the gas flowrate is *** the present paper, the current distribution on anode surface and plasma property of the HCA under low pressure conditions has been made clear and the total heat energy to the anode has been discussed to understand the melting property of HCA welding. Result shows that HCA in the case of low gas flowrate is a high energy source and the high-energy input to the anode contributes to the huge penetration.

关键词： Hollow cathode arc Input energy Penetration Plasma property Low pressure arc

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Whole-exome sequencing for a more accurate diagnosis of intraductal papillary neoplasms of the bile duct

引用

Gastroenterology Report 2022年第1期10卷 618-621页

作者： Tomoaki Matsumori Norimitsu Uza Nobuyuki Kakiuchi Toshihiro Morita Yoshihiro nishikawa Masahiro Shiokawa Kojiro Taura Yuzo Kodama hiroshi Seno Department of Gastroenterology and Hepatology Graduate School of MedicineKyoto UniversityKyotoJapan Department of Phathology and Tumor Biology Kyoto UniversityKyotoJapan Department of Hepato-Biliary-Pancreatic Surgery Graduate school of MedicineKyoto UniversityKyotoJapan Department of Gastroenterology Kobe UniversityKobeJapan

Introduction According to the World Health Organization(WHO,2018),intraductal papillary neoplasms of the bile duct(IPNB)are characterized as polypoid masses in dilated bile ducts;additionally,invasive IPNB occasionally presents with a nodular surface or mass formation[1,2].The IPNB diagnostic criteria are,however,often ambiguous,*** IPNB is considered a type of cancer and whether it must have mucus production are debatable[3].Therefore,establishing new IPNB diagnostic criteria based on an alternative approach,such as whole-exome sequencing,is ***,we present a case of IPNB with atypical features on which we performed a detailed genetic analysis to determine the genetic,morphological,and histological features of IPNB in this case.

关键词： neoplasms bile diagnosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atomic force microscopy analysis of orientation and bending of oligodeoxynucleotides in polypod-like structured DNA

引用

Nano Research 2015年第12期8卷 3764-3771页

作者： Tomoki Shiomi Mengmeng Tan Natsuki Takahashi Masayuki Endo Tomoko Emura Kumi Hidaka hiroshi Sugiyama Yuki Takahashi Yoshinobu Takakura Makiya nishikawa Department of Biopharmaceutics and Drug Metabolism Graduate School of Pharmaceutical Sciences Kyoto University Sakyo-ku Kyoto 606-8501 Japan Institute for Integrated Cell-Material Sciences (WPI-iCeMS) Kyoto University Sakyo-ku Kyoto 606-8501 Japan Department of Chemistry Graduate School of Science Kyoto University Sakyo-ku Kyoto 606-8502 Japan

我们以前证明象多足一样组织了 DNA，或 polypodna，与三或更构造了 oligodeoxynucleotides (ODN ) ，被象树枝状的房间和巨噬细胞那样的有免疫力的房间高效地收起，取决于它的结构的复杂性。包括 polypodna 的 ODN 应该弯曲形成象多足... 详细信息

我们以前证明象多足一样组织了 DNA，或 polypodna，与三或更构造了 oligodeoxynucleotides (ODN ) ，被象树枝状的房间和巨噬细胞那样的有免疫力的房间高效地收起，取决于它的结构的复杂性。包括 polypodna 的 ODN 应该弯曲形成象多足一样结构，并且可以那么由采用 bendtype 符合构造或跨类型的符合构造做。这里，我们试着阐明取向并且用原子力量显微镜学(AFM ) 在 polypodnas ODN 弯曲。我们设计了 pentapodnas 的二种类型(即，有五个豆荚的 polypodna ) 使用 60- 到 88 底 ODN，它然后在 DNA origami 上被使不能调动装裱。AFM 成像证明在 pentapodna 的 ODN 采用了拐弯类型符合构造。当他们在非强迫的条件下面在框架上被使不能调动时， Tetrapodna 和 hexapodna 也采用了拐弯类型符合构造。这些调查结果提供向协调设计的有用信息，和 structureactivity 关系为，许多 DNA nanostructures。

关键词：原子力显微镜分析反义寡核苷酸弯曲型结构 DNA 取向树突状细胞免疫细胞巨噬细胞

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In-situ evaluation for activated concrete in accelerator facility with scintillation-type gamma-ray spectrometer

引用

辐射防护 2020年第6期40卷 545-549页

作者： Go Yoshida hiroshi Matsumura Koichi nishikawa Akihiro Toyoda Yoshiharu Miyazaki Kazuyoshi Masumoto Hajime Nakamura Taichi Miura High Energy Accelerator Research Organization(KEK) 1-1 OhoTsukubaIbaraki 305-0801Japan The Medical and Pharmacological Research Center Foundation Wo-32Inoyama-machiHakuiIshikawa 925-0613Japan

The assessment of activated concrete is particularly difficult during the decommissioning of an accelerator *** analysis by core boring is the only method of investigating the activity of concrete *** address this problem,an in-situ and nondestructive analysis method was developed to determineγ-ray-emitting nuclides and their specific activities in the concrete walls and floor by using a portable germanium semiconductor *** this work,we examined a substitute for Ge detector to establish a simpler and more convenient *** candidates,we focused on some scintillation type spectrometers,and the possibility of a substitute for a Ge detector was examined by both simulation and *** detection limits were roughly estimated through Monte Carlo simulation for various scintillation crystals,and it was found that 1.5-inch LaBr3,CeBr3,and SrI2 could distinguish the clearance *** was confirmed that the 1.5-inch LaBr3 could reproduce the calibration curve of the Ge detector in the *** required thickness and length of the radiation shield for suppressing the background radiation during the measurement was also determined for the convenience of an actual decommissioning work.

关键词： activation accelerator concrete scintillation detector PHITS code

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Human epidermal growth factor receptor 2 targeted therapy in endometrial cancer:Clinical and pathological perspectives

引用

World Journal of Clinical Oncology 2021年第10期12卷 868-881页

作者： Ayumi Saito hiroshi Yoshida Tadaaki nishikawa Kan Yonemori Department of Breast and Medical Oncology National Cancer Center HospitalTokyo 1040045Japan Department of Diagnostic Pathology National Cancer Center HospitalTokyo 1040045Japan

Endometrial cancer is the most common gynecological cancer in developed countries,and its incidence has *** majority of patients with endometrial cancer have an early disease and favorable prognosis;however,a significant proportion of endometrial cancer,which mainly comprises high-grade or type II endometrial cancer such as serous,clear cell,and carcinosarcoma,shows advanced/recurrent disease and dismal *** therapeutic development is required for patients with aggressive endometrial *** genomic and immunohistochemical analyses revealed human epidermal growth factor receptor 2(HER2)overexpression/gene amplification in 20%-40%of patients with type II endometrial ***,HER2 targeted therapy has been developed for various major cancers,including breast and gastric ***,recent advances in HER2 targeted therapy for patients with type II endometrial cancer are also expected to ***,an optimized HER2 test for endometrial cancer as companion diagnostics should be *** this review,we summarize the recent findings on endometrial cancer,current treatment,optimized HER2 testing,key clinical trials on HER2 targeted therapy,and future directions in aggressive endometrial cancer,including serous carcinoma and carcinosarcoma.

关键词： Endometrial cancer Serous carcinoma Carcinosarcoma Human epidermal growth factor receptor 2 Chemotherapy Antibody-drug conjugates

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nondestructive high-sensitivity measurement method for activation estimation in accelerator room concrete

引用

辐射防护 2020年第6期40卷 677-682页

作者： hiroshi Matsumura Go Yoshida Akihiro Toyoda Kazuyoshi Masumoto Hajime Nakamura Taichi Miura Koichi nishikawa Kotaro Bessho Kimikazu Sasa Tetsuaki Moriguchi Fumiyoshi Nobuhara Yoko Nagashima High Energy Accelerator Research Organization(KEK) Oho 1-1Tsukuba Ibaraki 305-0801Japan University of Tsukuba 1-1-1 TennodaiTsukubaIbaraki 305-8577Japan Tokyo Nuclear Services Co. Ltd.1-3-5.TaitoTaito-kuTokyo 110-0016Japan

This study established a method for easily and quickly estimating the specific activity produced in the concrete walls and floors of accelerator rooms during long-term operation of accelerator,for advanced zoning of activated/nonactivated areas in planning the decommissioning of an *** propose a new,highly sensitive method for nondestructively estimating the specific activity in concrete that can be applied to activation *** this method,instead of direct determination of the specific activities of important long-half-life radionuclides for decommissioning,such as 152 Eu and 60 Co,we determine the specific activities of short-half-life radionuclides,24 Na and 56 Mn,in situ to obtain neutron *** obtained neutron flux and accelerator operation history yield the specific activities of 152 Eu and 60 Co for the advance zoning of activated/non-activated *** method is a powerful long-term prediction tool for concrete activation.

关键词： accelerator activation concrete specific activity decommissioning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bone Formation in a Scaffold Composed of Cylindrical Hydroxyapatite and Tryptophan- or Lysine-Coated Sponge <i>in Vivo</i>

引用

Journal of Biomedical Science and Engineering 2015年第6期8卷 389-398页

作者： Masataka Yoshikawa Hideyuki Kakigi hiroshi Maeda Ikuo nishikawa Hideaki Ikenaga Takeshi Inamoto Norimasa Tsuji Department of Endodontics Osaka Dental University Osaka Japan

Because of the three-dimensional structure of bone or hard tissue such as a tooth, a scaffold is necessary for its regeneration by cellular engineering. Commonly, for in vivo examination, hydroxyapatite (HA) has been used as such a scaffold. Cylindrical HA with a hollow center, which included a columnar formalin-treated polyvinyl alcohol sponge, was used in this examination as a scaffold. The sponge had been coated with L-tryptophan or L-lysine before insertion into the hollow center of the HA. Rat bone marrow cells (rBMCs) derived from the femur were seeded in the sponge before insertion into the hollow center of HA. The number of rBMCs seeded in each sponge was 1.5 × 106. These scaffolds were implanted subcutaneously into the backs of Fischer 344 rats for 6 weeks. In the amino-acid-coated sponge in HA, osteogenesis was found histologically. An osteocalcin level of approximately 10 ug was measured in the scaffolds with L-tryptophan-coated formalized poly-vinyl alcohol sponge containing rBMCs, 4 ug on average in the scaffolds with L-lysine-coated sponge containing the cells and about 2 ug in each scaffold with uncoated sponge containing the cells. The structure of the scaffolds used in this study was thought to be suitable for osteogenesis by rBMCs. It was concluded that tryptophan, as a factor for bone formation by stem cells, functioned by promoting cell adhesion and the differentiation of stem cells into osteoblasts.

关键词： Scaffold Hydroxyapatite Bone Marrow Cells L-Tryptophan L-Lysine Poly-Vinyl Formal Sponge

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：