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Wafer scale direct-write of Ge and Si nanostructures with conducting stamps and a modified mask aligner

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Nano Research 2013年第4期6卷 263-268页

作者： hideki Sato Stephanie E. Vasko Marco Rolandi Department of Materials Science and Engineering University of Washington Seattle WA 9819S USA Japan Patent Office Tokyo 100-8915 Japan Department of Chemistry University of Washington Seattle WA 98195 USA

The broad availability of high throughput nanostructure fabrication is essential for advancement in nanoscale science. Large-scale manufacturing developed by the semiconductor industry is often too resource-intensive for medium scale laboratory prototyping. We demonstrate the inexpensive wafer scale direct- write of Ge and Si nanostructures with a 4-inch mask aligner retrofitted with a conducting microstructured stamp. A bias applied between the stamp and an underlying silicon substrate results in the reaction of diphenylgermane and diphenylsilane precursors at the stamp--substrate interface to yield the direct- write of Ge and Si nanostructures in determined locations. With the increasing number of outdated mask aligners available from the semiconductor industry and an extensive library of liquid precursors, this strategy provides facile, inexpensive, wafer scale semiconductor direct-write for applications such as electronics, photonics, and photovoltaics.

关键词： Ge Si nanolithography microcontact printing scanning probe lithography

Quantum information entropies of the eigenstates for the Pschl-Teller-like potential

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Chinese Physics B 2013年第5期22卷 113-117页

作者： Guo-Hua Sun M. Avila aoki Shi-Hai Dong Centro Universitario Valle de Chalco Universidad Autónoma del Estado de México Departamento de Física Escuela Superior de Física y MatemáticsInstituto Politécnico Nacional

Shannon entropy for lower position and momentum eigenstates of Ptschl-Teller-like potential is evaluated. Based on the entropy densities demonstrated graphically, we note that the wave through of the position information entropy density p （x） moves right when the potential parameter V1 increases and its amplitude decreases. However, its wave through moves left with the increase in the potential parameter 丨V2丨. Concerning the momentum information entropy density p（p）, we observe that its amplitude increases with increasing potential parameter V1, but its amplitude decreases with increasing丨V2丨. The Bialynicki-Birula-Mycielski （BBM） inequality has also been tested for a number of states. Moreover, there exist eigenstates that exhibit squeezing in the momentum information entropy. Finally, we note that position information entropy increases with V1, but decreases with 丨V2丨, However, the variation of momentum information entropy is contrary to that of the position information entropy.

关键词： bound states quantum information entropy Poschl-Teller-like potential

On Using Physico-Chemical Properties of Amino Acids in String Kernels for Protein Classification via Support Vector Machines

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Journal of Systems Science & Complexity 2015年第2期28卷 504-516页

作者： LI Limin aoki-KINOSHITA Kiyoko F CHING Wai-Ki JIANG Hao Institute of Information and System Science Xi'an Jiaotong University Department of Bioinformatics Faculty of EngineeringSoka University Advanced Modeling and Applied Computing Laboratory Department of MathematicsThe University of Hong Kong Department of Mathematics School of InformationRenmin University of China

String kernels are popular tools for analyzing protein sequence data and they have been successfully applied to many computational biology problems. The traditional string kernels assume that different substrings are independent. However, substrings can be highly correlated due to their substructure relationship or common physico-chemical properties. This paper proposes two kinds of weighted spectrum kernels： The correlation spectrum kernel and the AA spectrum kernel. We evMuate their performances by predicting glycan-binding proteins of 12 glycans. The results show that the correlation spectrum kernel and the AA spectrum kernel perform significantly better than the spectrum kernel for nearly all the 12 glycans. By comparing the predictive power of AA spectrum kernels constructed by different physico-chemical properties, the authors can also identify the physico- chemical properties which contributes the most to the glycan-protein binding. The results indicate that physico-chemical properties of amino acids in proteins play an important role in the mechanism of glycamprotein binding.

关键词： AAindex AA spectrum kernel correlation spectrum kernel physico-chemical properties string kernel weighted spectrum kernel.

Influences of the Exhaust Flow on the Boundary Layer Flow on the Wafer Surface in Spin Coating System

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Journal of Thermal Science 2005年第2期14卷 130-135页

作者： Seiichi KIMURA Mizue MUNEKATA Hiroaki KURISHIMA Kazuyoshi MATSUZAKI hideki OHBA Graduate School of Science and Technology Kumamoto University Mechanical Engineering and Materials Science Kumamoto UniversityTokyo Electron Kyushu LTDTokyo Electron AT LTDMechanical Engineering and Materials Science Kumamoto University

Recently, development of high technology has been required for the formation of thin uniform film in manufacturing processes of semiconductor as the semiconductor become more sophisticated. Spin coating is usually used for spreading photoresist on a wafer surface. However, since rotating speed of the disk is very high in spin coating, the dropped resist scatters outward and reattaches to the film surface. So, the scattered resist is removed by the exhaust flow generated at the gap between the wafer edge and the catch cup. It is seriously concerned that the stripes called Ekman spiral vortices appears on the disk in the case of high rotating speed and the film thickness increases near the wafer edge in the case of low rotating speed, because it prevent the formation of uniform film. The purpose of this study is to make clear the generation mechanism of Ekman spiral vortices and the influence of exhaust flow on it Moreover the influence of the catch cup geometry on the wafer surface boundary layer flow is investigated.

关键词： rotating disk flow spin coating boundary layer flow hot-wire measurement

Relation between the Three-dimensional Flow Structure and Aerodynamic Sound Generated from Inclined Circular Cylinder

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Journal of Thermal Science 2004年第2期13卷 127-132页

作者： Mitsuru SHINGAI Yasutake HARAMOTO Kazuyoshi MATSUZAKI Mizue MUNEKATA hideki OHBA Dept. of Mechanical Engineering and Materials Science Kumamoto University Kurokami 2-39-1 Kumamoto 860-8555 Japan Mitsui Miike Machinery Co. LTD Asahi-machi 2-28 Ohmuta Fukuoka 836-8588 Japan

The major causes of the sound pressure level (SPL) variation due to the changes of the inclined angle of a circular cylinder and the aspect ratio (ratio of distance between endplates to cylinder diameter) were investigated. The velocity fluctuation of the wake and the surface pressure fluctuation of the cylinder were measured in a low noise wind tunnel to find the correlation length, coherent output power and Strouhal number. The results show that the changes of these values qualitatively correspond with the change of SPL. Flow visualization tests are performed to clarify the variation of wake in relation with inclined angle and aspect ratio. It is found that the spanwise structure of Karman’s vortex street is broken down by the upward flows generated around the bottom endplate, and the degree of the interference between the upward flow and Karman’s vortex street is smaller when the aspect ratio is larger.

关键词： aerodynamic sound correlation length coherent output power Strouhal number flow visualization.

Micronization of curcumin with biodegradable polymer by supercritical anti-solvent using micro swirl mixer

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Frontiers of Chemical Science and Engineering 2018年第1期12卷 184-193页

作者： Kimthet Chhouk Wahyudiono hideki Kanda Shin-Ichro Kawasaki Motonobu Goto Department of Chemical Engineering Nagoya University Nagoya 464-8603 Japan Department of Chemical Engineering and Food Technology Institute of Technology of Cambodia Phnom Penh Cambodia Department of Materials Process Engineering Nagoya University Nagoya 464-8603 Japan Research Institute for Chemical Engineering Process Technology National Institute of Advanced Industrial Science and Technology Sendai 983-8551 Japan

Curcumin is a hydrophobic polyphenol compound exhibiting a wide range of biological activities such as anti-inflammatory, anti-bacterial, anti-fungal, anti-carcinogenic, anti-human immunodeficiency virus, and antimicrobial activity. In this employed to produce the work, a swirl mixer was micronized curcumin with polyvinylpyrrolidone （PVP） by the supercritical antisolvent process to improve the bioavailability of curcumin. The effects of operating parameters such as curcumin/PVP ratio, feed concentration, temperature, pressure, and CO2 flow rate were investigated. The characterization and solubility of particles were determined by using scanning electron microscopy, Fourier Transform Infrared spectroscopy, and ultra-violet-visible spectroscopy. The result shows that the optimal condition for the production of curcumin/PVP particles is at curcumin/PVP ratio of 1：30, feed concentration of 5 mg·mL^-1, temperature of 40 ℃, pressure of 15 MPa, and CO2 flow rate of 15 mL·min^-1. Moreover, the dissolution of curcumin/PVP particles is faster than that of raw curcumin.

关键词： micronization curcumin polyvinylpyrrolidone supercritical anti-solvent swirl mixer

Application of yeast spores as β-glucan particles

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Particuology 2022年第12期71卷 34-40页

作者： Guoyu Liu Yan Yang Hiroyuki Tachikawa Xiao-Dong Gao hideki Nakanishi Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of EducationSchool of BiotechnologyJiangnan UniversityWuxi 214122China Department of Applied Biological Chemistry Graduate School of Agricultural and Life SciencesUniversity of TokyoTokyo 113-8657Japan Collaborative Research Institute for Innovative Microbiology University of TokyoTokyo 113-8657Japan

β-Glucan exhibits various beneficial biological activities including *** polysaccha-ride is present in the cell wall of microorganisms including the yeast Saccharomyces *** vegetative yeast cells are used as dietary supplements,β-glucan in the vegetative cell wall is covered with *** nutrient starvation,yeast cells differentiate into dormant cell spores.β-Glucan is also present in the spore wall,but spores have been poorly studied as application *** spore wall consists of four layers andβ-glucan forms the third layer from the ***,unlike vegeta-tive cells,theβ-glucan layer can be exposed to the cell surface in spores by genetic *** example,chs3Δmutant spores exhibit such a spore wall ***-1 is the primary receptor forβ-glucan in mammals and,its activation induces phagocytosis and proinflammatory cytokine *** found that chs3Δspores are phagocytosed in mammalian cells in a manner dependent on dectin-1 and induce higher levels of TNF-αand IL-6 than vegetative *** results demonstrate that chs3Δspores areβ-glucan particles with immunostimulatory ***,they would be attractive materials for application in the food industry.

关键词： Saccharomycescerevisiae Sporewall β-glucan Dectin-1 Immunostimulation

Preoperative portal vein embolization for hepatocellular carcinoma: consensus and controversy

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World Journal of Hepatology 2016年第9期8卷 439-445页

作者： Taku aoki Keiichi Kubota Second Department of Surgery Dokkyo Medical University

Thirty years have passed since the first report of portal vein embolization(PVE),and this procedure is widely adopted as a preoperative treatment procedure for patients with a small future liver remnant(FLR).PVE has been shown to be useful in patients with hepatocellular carcinoma(HCC)and chronic liver ***,special caution is needed when PVE is applied prior to subsequent major hepatic resection in cases with cirrhotic livers,and volumetric analysis of the liver segments in addition to evaluation of the liver functional reserve before PVE is mandatory in such *** in the embolic material and selection of the treatment approach,and combined use of PVE and transcatheter arterial embolization/chemoembolization have yielded improved outcomes after PVE and major hepatic resections.A novel procedure termed the associating liver partition and portal vein ligation for staged hepatectomy has been gaining attention because of the rapid hypertrophy of the FLR observed in patients undergoing this procedure,however,application of this technique in HCC patients requires special caution,as it has been shown to be associated with a high morbidity and mortality even in cases with essentially healthy livers.

关键词： Hepatocellular carcinoma Future liver remnant Poral vein embolization Liver functional reserve The associating liver partition and portal vein ligation for staged hepatectomy

Introduction to a Major Project of the National Social Science Fund:Research on China's Industrial Heritage Conservation System

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Built Heritage 2018年第1期2卷 3-18页

作者： Subin Xu Nobuo aoki School of Architecture Tianjin UniversityTianjinChina

Since the 1980s,China has undergone a series of important changes including industrial restructuring,land transfer,and *** have given rise to the issue of how to address industrial heritage within many *** author’s research team has undertaken a National Social Science’s Major Project(the highest level of Chinese national social science research)titled‘Systematic Research on the Protection of Urban Industrial Heritage in Modern China’.This is the first nationwide and systematic study of industrial heritage in *** paper provides a brief introduction to the study’s framework and current research achievements,including:(1)the study of industrial modernisation processes,including international perspectives;(2)industrial heritage information acquisition and database setup;(3)estimation of industrial heritage value;(4)studies of the planning and design strategy of industrial heritage reutilisation;and(5)the transition from industrial heritage conservation to the development of a cultural industry.

关键词： China industrial heritage technological history database value evaluation adaptive reuse cultural industry