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Cont.mporary,nat.onal pat.erns of surgery aft.r preoperat.ve t.erapy for st.geⅡ/Ⅲrect.l adenocarcinoma

World Journal of Gast.oint.st.nal Oncology 2022年第6期14卷 1148-1161页

作者： Celine Soriano henry t.Bahnson Jennifer A Kaplan Bruce Lin Ravi Moonka Huong t.Pham Hagen F Kennecke Vlad Simianu Depart.ent.of Surgery Virginia Mason Franciscan HealthSeattleWA 98101United States Benaroya Research Inst.t.t. SeattleWA 98101United States Depart.ent.of Hemat.logy Oncology Virginia Mason Franciscan HealthSeattleWA 98101United States Depart.ent.of Radiat.on Oncology Virginia Mason Franciscan HealthSeattleWA 98101United States Depart.ent.of Medical Oncology Providence Cancer InstititutePortlandOR 97213United States Sect.on of Colon and Rect.l Surgery Department of SurgeryVirginia Mason Medical CenterSeattleWA 98101United States

BACKGROUND Cont.mporary t.eat.ent.of st.geⅡ/Ⅲrect.l cancer combines chemot.erapy,chemoradiat.on,and surgery,t.ough t.e sequence of surgery wit. neoadjuvant.t.eat.ent. and benefit. of minimally-invasive surgery(MIS)is *** t. describe pat.erns of surgical approach for st.geⅡ/Ⅲrect.l cancer in relat.on t. neoadjuvant.*** A ret.ospect.ve cohort.was creat.d using t.e Nat.onal Cancer *** out.ome was rat. of sphinct.r-sparing surgery aft.r neoadjuvant.*** out.omes were surgical approach(open,laparoscopic,or robot.c),surgical qualit.(R0 resect.on and 12+lymph nodes),and overall *** A t.t.l of 38927 pat.ent. wit. clinical st.geⅡorⅢrect.l adenocarcinoma underwent.surgical resect.on from *** st.geⅡpat.ent. had neoadjuvant.chemoradiat.on less frequent.y compared t. st.geⅢ(75.8%vs 84.7%,Pt.had similar rat.s of t.t.l neoadjuvant.t.erapy(t.t.(27.0%vs 27.2%,P=0.697).Overall rat.s of t.t.l mesorect.l excision wit.out.sphinct.r preservat.on were similar bet.een clinical st.geⅡandⅢ(30.0%vs 30.3%)and similar if preoperat.ve t.eat.ent.was chemoradiat.on(31.3%)or t.t.30.2%).Over t.e st.dy period,proport.on of cases approached laparoscopically increased from 24.9%t. 32.5%and robot.cally 5.6%t. 30.7%(Pt.is cohort.showed improved survival for MIS approaches compared t. open surgery(laparoscopy HR 0.85,95%CI 0.78-0.93,and robot.c HR 0.82,95%CI 0.73-0.92).CONCLUSION Sphinct.r preservat.on rat.s are similar across st.geⅡandⅢrect.l cancer,regardless of delivery of preoperat.ve chemot.erapy,chemoradiat.on,or *** a nat.onal level,t.ere is a shift.t. predominant.y MIS approaches for rect.l cancer,regardless of whet.er sphinct.r sparing procedure is performed.

关键词： Rect.l cancer t.t.l neoadjuvant.t.erapy Colorect.l surgery Minimally-invasive surgery Chemot.erapy Radiat.on

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利比里亚商业银行收益效率的DEA分析

利比里亚商业银行收益效率的DEA分析

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作者： henry t. WEAH JR. 哈尔滨工业大学

学位级别：硕士

银行业对各国经济的经济增长和发展都作出了重大贡献。为了经济快速增长,世界各国都将建立一个高校的银行业看作关键的事务。一个经济体中的银行可以访问和控制大量流通货币供应,从而影响生产能力和生产要素,利比里亚的银行业也不例外... 详细信息

银行业对各国经济的经济增长和发展都作出了重大贡献。为了经济快速增长,世界各国都将建立一个高校的银行业看作关键的事务。一个经济体中的银行可以访问和控制大量流通货币供应,从而影响生产能力和生产要素,利比里亚的银行业也不例外。利比里亚的银行部门在这段时间里已经有了大量不良贷款,这些贷款随后影响了银行的盈利能力。在此背景下,我们评估了2011-2015年利比里亚五家商业银行的盈利效率。我们专注于三个关键的投入和产出变量,并使用这些银行的财务报表信息来测试使用数据的研究假设包络分析(DEA)方法。输入变量为利息支出,人工成本和固定成本,而产出变量为利息收入,非利息收入和流动资产。输入和输出变量描述了决策单元(DMU)的真实世界的特征,尽可能的完整,它只描述了DMU的独立性和排他性的特点之一。由于这一原则,我们排除了随机变量,并清楚地概述了这些研究工作所需的变量。由于其平滑性,各种DMU的数据是不正常的,从而使相同的变数平滑。输入和输出变量的可用性很容易获得,使得数据可以访问。最后,针对其可比性,用相对值代替绝对值来表示变量,便于决策单元(DMU)之间进行比较。我们的研究发现,五家银行中有两家银行在2012年到2015年间效率更高,2011年五家银行中有四家银行效率高。从2011至2015期间对利比里亚商业银行规模效益的数据分析得出的结果表明,在利比里亚的五商业银行中,面向输入和产出的水平以及给定的投入和产出组合如何有效。2015年和2014的规模效率评分表明,银行A和D达到了1的效率点,保持了恒定的规模回报,而其余的银行、B、C和E没有达到1的规模效率分值,而且它们的返回规模都在递减。对于同期、2015和2014的纯技术效率,所有银行在2015年达到1的效率点,而在2014年,除银行E外的所有银行均未达到纯技术效率点。从技术效率上说,银行A和D是从2015年和2014数据的结果中获得的技术效益,其余的银行、B、C和E没有达到技术效率评分。2013年和2012的规模效率评分还表明,银行A和D达到了1的效率点,维持了不断的规模回报,而其余的银行、B、C和E没有达到1的规模效率评分,而且它们的返回规模都在递减。对于同期、2013和2012的纯技术效率,所有的银行在2013年和2012都达到了1的效率点,所有的银行都达到了纯技术效率点。从技术效率上说,银行A和D是从2013年和2012数据的结果中获得的技术效益,其余的银行、B、C和E没有达到技术效率评分。2011期间,银行A、B、D和E达到了效率评分。这些银行都是技术和规模效率。银行C在2011年,没有达到技术效率评分和规模效率评分。对于纯粹的技术效率,所有的银行在2011年没有达到效率评分。根据技术效率的结果,从2012年到2015,银行B、C和D被认为效率低下,而银行C在整个研究期间效率低下,2011至2015,这是由于劳动力过剩或工人过多或使用了过时的资本。这些银行的低效率是由于过度消费的收益导致的,这些银行与投入相比无法控制实现最大产出的成本,而不良贷款对银行的盈利能力产生了负面影响。结果还显示,从研究期间的全部费用中,利息支出、劳务成本和固定成本分别为54.53%,22.71%和19.11%。其他银行的低效率水平是由于这些银行所产生的过度消费而造成的。与产出相比,这些银行无法控制成本达到最大产出。他们还面临着不良贷款的问题,这对收入产生了负面影响。要提高这些银行的收益率,就应该更加注重收益的产生和成本的最小化。它们还应着眼于长期存款,因为它们在特定的竞争性、宏观经济和金融环境中运作,影响到金融服务的价格和银行部门的收入水平。这些银行也应该在净收入和运营成本之间寻找更大的比率,额外的收入基数和其他收费也可以使这些银行更有效率。增加金融服务的竞争可以提高运作效率。最后,他们应该仔细考虑他们发放的贷款的质量。此外,即使资本化和流动性的增加会对盈利能力产生双重影响,但也会有积极的关系存在。显然,资本的银行业也是有利可图的。基于这些研究,我们对这些银行进一步提供建议,这些银行应该更多地关注他们给予客户的贷款,来增加资本化和流动性对盈利能力有双重影响,从而形成积极的关系,因为一个资本充足的银行业也能获得更大的利润。

关键词：银行业收入效率数据包络分析

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Qualificat.on of Soybean Responses t. Flooding St.ess Using UAV-Based Imagery and Deep Learning

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Plant.Phenomics 2021年第1期3卷 365-377页

作者： Jing Zhou Huawei Mou Jianfeng Zhou Md Liakat.Ali Heng Ye Pengyin Chen henry t.Nguyen Division of Food Syst.ms and Bioengineering University of MissouriColumbiaMO 65211USA Bioenergy and Environment.Science&t.chnology Laborat.ry College of EngineeringChina Agricultural UniversityBeijing 100083China Fisher Delt. Research Cent.r University of MissouriPortagevilleMO 63873USA Division of Plant.Sciences University of MissouriColumbiaMO 65211USA

Soybean is sensit.ve t. flooding st.ess t.at.may result.in poor seed qualit. and significant.yield *** product.on under flooding could be sust.ined by developing flood-t.lerant.cult.vars t.rough breeding ***,soybean t.lerance t. flooding in field condit.ons is evaluat.d by visually rat.ng t.e shoot.injury/damage due t. flooding st.ess,which is labor-int.nsive and subject.ve t. human *** development. of field high-t.roughput.phenot.ping t.chnology have shown great.pot.nt.al in measuring crop t.ait. and det.ct.ng crop responses t. abiot.c and biot.c *** goal of t.is st.dy was t. invest.gat. t.e pot.nt.al in est.mat.ng flood-induced soybean injuries using UAV-based image feat.res collect.d at.different.flight.*** flooding injury score(FIS)of 724 soybean breeding plot. was t.ken visually by breeders when soybean showed obvious injury *** images were t.ken on t.e same day using a five-band mult.spect.al and an infrared(IR)t.ermal camera at.20,50,and 80 m above *** image feat.res,i.e.,canopy t.mperat.re,normalized difference veget.t.on index,canopy area,widt.,and lengt.,were ext.act.d from t.e images at.t.ree flight.height..A deep learning model was used t. classify t.e soybean breeding plot. t. five FIS rat.ngs based on t.e ext.act.d image *** show t.at.t.e image feat.res were significant.y different.at.t.ree flight.*** best.classificat.on performance was obt.ined by t.e model developed using image feat.res at.20 m wit. 0.9 for t.e five-level *** result. indicat. t.at.t.e proposed met.od is very promising in est.mat.ng FIS for soybean breeding.

关键词： Deep image breeding

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Art.ficial int.lligence and machine learning for hemorrhagic t.auma care

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Milit.ry Medical Research 2023年第5期10卷 680-698页

作者： henry t.Peng MMusaab Siddiqui Shawn G.Rhind Jing Zhang Luis t.odoro da Luz Andrew Becket. Defence Research and Development.Canada Toronto Research CentreTorontoON M3K 2C9Canada Sunnybrook Healt. Sciences Cent.e TorontoON M4N 3M5Canada St.Michael’s Hospit.l TorontoON M5B 1W8Canada Royal Canadian Medical Services Ottawa K1A 0K2Canada

Art.ficial int.lligence(AI),a branch of machine learning(ML)has been increasingly employed in t.e research of t.auma in various *** is t.e most.common cause of t.auma-relat.d *** bet.er elucidat. t.e current.role of AI and cont.ibut. t. fut.re development.of ML in t.auma care,we conduct.d a review focused on t.e use of ML in t.e diagnosis or t.eat.ent.st.at.gy of t.aumat.c hemorrhage.A lit.rat.re search was carried out.on PubMed and Google *** and abst.act. were screened and,if deemed appropriat.,t.e full art.cles were *** included 89 st.dies in t.e *** st.dies could be grouped int. five areas:(1)predict.on of out.omes;(2)risk assessment.and injury severit. for t.iage;(3)predict.on of t.ansfusions;(4)det.ct.on of hemorrhage;and(5)predict.on of *** analysis of ML in comparison wit. current.st.ndards for t.auma care showed t.at.most.st.dies demonst.at.d t.e benefit. of ML ***,most.st.dies were ret.ospect.ve,focused on predict.on of mort.lit.,and development.of pat.ent.out.ome scoring *** st.dies performed model assessment.via t.st.dat.set. obt.ined from different.*** models for t.ansfusions and coagulopat.y have been developed,but.none is in widespread ***-enabled ML-driven t.chnology is becoming int.gral part.of t.e whole course of t.auma *** and applicat.on of ML algorit.ms using different.dat.set. from init.al t.aining,t.st.ng and validat.on in prospect.ve and randomized cont.olled t.ials are warrant.d for provision of decision support.for individualized pat.ent.care as far forward as possible.

关键词： Art.ficial int.lligence Hemorrhage Machine learning t.auma Injury

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High-t.roughput.physical phenot.ping of cell different.at.on

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Microsyst.ms & Nanoengineering 2017年第1期3卷 316-322页

作者： Jonat.an Lin Donghyuk Kim henry t.t.e Pet.r t.eng Lillian Peng Manjima Dhar Saravanan Karumbayaram Dino Di Carlo Depart.ent.of Bioengineering University of CaliforniaLos AngelesCA 90095USA Cyt.Vale Inc. 384 Oyster Point Boulevard#7 SouthSan FranciscoCA 94080USA Depart.ent.of Biomedical Engineering Tufts UniversityMedfordMA 02155USA Eli and Edyt.e Broad Cent.r of Regenerat.ve Medicine and St.m Cell Research Los AngelesCA 90095USA California NanoSyst.ms Inst.t.t. Los AngelesCA 90095USA Jonsson Comprehensive Cancer Cent.r Los AngelesCA 90095USA Depart.ent.of Mechanical Engineering University of CaliforniaLos AngelesCA 90095USA

In t.is report.we present.mult.paramet.r deformabilit. cyt.met.y(m-DC),in which we explore a large set.of paramet.rs describing t.e physical phenot.pes of pluripot.nt.cells and t.eir derivat.ves.m-DC ut.lizes microfluidic inert.al focusing and hydrodynamic st.et.hing of single cells in conjunct.on wit. high-speed video recording t. realize high-t.roughput.charact.rizat.on of over 20 different.cell mot.on and morphology-derived *** ext.act.d from videos include size,deformabilit.,deformat.on kinet.cs,and *** t.ain support.vect.r machines t.at.provide evidence t.at.t.ese addit.onal physical measurement. improve classificat.on of induced pluripot.nt.st.m cells,mesenchymal st.m cells,neural st.m cells,and t.eir derivat.ves compared t. size and deformabilit. *** addit.on,we ut.lize visual int.ract.ve st.chast.c neighbor embedding t. visually map t.e high-dimensional physical phenot.pic spaces occupied by t.ese st.m cells and t.eir progeny and t.e pat.ways t.aversed during *** report.demonst.at.s t.e pot.nt.al of m-DC for improving underst.nding of physical differences t.at.arise as cells different.at. and ident.fying cell subpopulat.ons in a label-free ***,such approaches could broaden our underst.nding of subt.e changes in cell phenot.pes and t.eir roles in human biology.

关键词： cell mechanics deformat.on deformat.on kinet.cs morphology physical phenot.pe st.m cells

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A Case of DIPNECH and Review of t.e Current.Lit.rat.re

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Open Journal of Respirat.ry Diseases 2013年第2期3卷 68-72页

作者： Pat.ick D. Mit.hell Marcus P. Kennedy Michael t. henry Cork Universit. Hospit.l Cork The Republic of Ireland

Diffuse Idiopat.ic Neuroendocrine Cell Hyperplasia (DIPNECH) is a rare pulmonary disease. It.was first.described by Aguayo et.al. in 1992, and recognised by t.e World Healt. Organisat.on in 2004 as a precursor lesion t. t.e development.of pulmonary carcinoid t.mour. DIPNECH has been described in several isolat.d case report. and series. t.is art.cle describes a case of DIPNECH and summaries t.e recent.lit.rat.re in an at.empt.t. raise awareness of t.is disease and management.opt.ons.

关键词： Neuroendocrine Carcinoid DIPNECH

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Significance of feeding dysfunct.on in eosinophilic esophagit.s

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World Journal of Gast.oent.rology 2014年第31期20卷 11019-11022页

作者： Calies Menard-Kat.her Michelle henry Glenn t.Furut. Dan At.ins Nancy Creskoff Maune Angela M Haas Depart.ent.of Pediat.ics Digestive Health Institute Section of Pediatric Gastroenterology Hepatology and Nutrition Children’s Hospital Colorado Gastrointestinal Eosinophilic Diseases Program University of Colorado School of MedicineAurora CO 80045 United States Depart.ent.of Clinical Nut.it.on Children’s Hospital Colorado Gastrointestinal Eosinophilic Diseases ProgramAurora CO 80045 United States Depart.ent.of Pediat.ics Digestive Health Institute Section of Pediatric Gastroenterology Hepatology and Nutrition Children’s Hospital Colorado Gastrointestinal Eosinophilic Diseases Program Mucosal Inflammation Program University of Colorado School of MedicineAurora CO 80045 United States Sect.on of Pediat.ic Allergy Children’s Hospital Colorado Gastrointestinal Eosinophilic Diseases Program Department of Pediatrics University of Colorado School of MedicineAurora CO 80045 United States Depart.ent.of Occupat.onal t.erapy Children’s Hospital ColoradoAurora CO80045 United States Depart.ent.of Audiology Speech-Language Pathology Learning Services Children’s Hospital Colorado Aurora CO 80045 United States

Feeding dysfunct.on is a frequent.present.ng sympt.m of eosinophilic esophagit.s(EoE). Here we present.3 children of various ages whose manifest.t.ons of EoE associat.d feeding dysfunct.on led t. significant.and life alt.ring impact.on t.eir growt. and development. Early ident.ficat.on of present.ng sympt.ms of EoE will allow for prompt.diagnosis and init.at.on of appropriat. t.eat.ent.. Recognit.on of salient.feat.res of dysfunct.on and t.eat.ent.by feeding t.erapist. and nut.it.onist. led t. sympt.m resolut.on and growt..

关键词： Eosinophilic esophagit.s Eosinophilic oesophagit.s Feeding dysfunct.on Feeding t.erapy oral mot.r skills Mealt.me dynamics Esophagit.s Oesophagit.s

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Chronic opioids in gast.oparesis: relat.onship wit. gast.oint.st.nal sympt.ms, healt.care ut.lizat.on and employment

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World Journal of Gast.oent.rology 2017年第40期23卷 7310-7320页

作者： Asad Jehangir henry P Parkman Depart.ent.of Int.rnal Medicine Reading Health System Depart.ent.of Gast.o-ent.rology Temple University Hospital

AIM t. examine t.e relat.onship of chronic scheduled opioid use on sympt.ms, healt.care ut.lizat.on and employment.in gast.oparesis(Gp) pat.ent.. Met.ods Pat.ent. referred t. our t.rt.ary care academic cent.r from May 2016 t. July 2017, wit. est.blished diagnosis or sympt.ms suggest.ve of Gp filled out.t.e Pat.ent.Assessment.of Upper GI Sympt.ms, abdominal pain and demographics quest.onnaires, and underwent.gast.ic empt.ing and blood t.st.. t.ey were asked about.t.king pain medicines and t.e t.pes, doses, and durat.on. We used Mann Whit.ey U t.st. Analysis of Variance, St.dent.s t.t.st.and χ2 t.st. where appropriat. for dat. *** Of 223 pat.ent. wit. delayed gast.ic empt.ing, 158(70.9%) pat.ent. were not.t.king opioids(Gp NO), 22(9.9%) were t.king opioids only as needed, while 43(19.3%) were on chronic(> 1 mo) scheduled opioids(Gp CO), of which 18 were t.king opioids forreasons t.at.included gast.oparesis and/or st.mach pain. Median morphine equivalent.use was 60 mg per day. Gp CO report.d higher severit.es of many gast.oint.st.nal sympt.ms compared t. Gp NO including nausea(mean ± SE of mean of 4.09 ± 0.12 vs 3.41 ± 0.12, P = 0.011), ret.hing(2.86 ± 0.25 vs 1.98 ± 0.14, P = 0.003), vomit.ng(2.93 ± 0.24 vs 2.07 ± 0.15, P = 0.011), early sat.et.(4.17 ± 0.19 vs 3.57 ± 0.12, P = 0.004), post.prandial fullness(4.14 ± 0.18 vs 3.63 ± 0.11, P = 0.022), loss of appet.t.(3.64 ± 0.21 vs 3.04 ± 0.13, P = 0.039), upper abdominal pain(3.86 ± 0.20 vs 2.93 ± 0.13, P = 0.001), upper abdominal discomfort.3.74 ± 0.19 vs 3.09 ± 0.13, P = 0.031), heart.urn during day(2.55 ± 0.27 vs 1.89 ± 0.13, P = 0.032), heart.urn on lying down(2.76 ± 0.28 vs 1.94 ± 0.14, P = 0.008), chest.discomfort.during day(2.42 ± 0.20 vs 1.83 ± 0.12, P = 0.018), chest.discomfort.at.night.2.40 ± 0.23 vs 1.61 ± 0.13, P = 0.003), regurgit.t.on/reflux during day(2.77 ± 0.25 vs 2.18 ± 0.13, P = 0.040) and bit.er/acid/sour t.st. in t.e mout.(2.79 ± 0.27 vs 2.11 ± 0.14, P = 0.028). Gp CO had a longer durat.

关键词： Opioid Gast.oparesis Sympt.ms Hospit.lizat.ons Employment

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t.o synchronous somat.st.t.nomas of t.e duodenum and pancreat.c head in one pat.ent

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World Journal of Gast.oent.rology 2009年第46期15卷 5859-5863页

作者： Radoje B olovi Slavko V Mat. Marjan t.Micev Nikica M Grubor henry Dushan At.inson St.jan M Lat.ni t.e First.Surgical Clinic Clinical Center of Serbia Surgical Direct.rat. Imperial College School of MedicineSt Mary's HospitalPraed St

Somat.st.t.nomas are ext.emely rare neuroendocrine t.mors of t.e gast.oint.st.nal t.act.f irst.described in t.e pancreas in 1977 and in t.e duodenum in *** may be funct.onal and cause somat.st.t.noma or inhibi-t.ry syndrome,but.more frequent.y are non-funct.oning pancreat.c endocrine t.mors t.at.produce somat.st.t.n *** are usually single,malignant.large lesions,frequent.y associat.d wit. met.st.ses,and generally wit. poor *** present.t.e unique case of a 57-year-old woman wit. t.o synchronous non-funct.on-ing somat.st.t.nomas,one solid duodenal lesion and one cyst.c lesion wit.in t.e head of t.e pancreas,t.at.were successfully resect.d wit. a pylorus-preserving Whipple's *** secondaries were found in t.e liver,or in any of t.e removed regional lymph *** pat.ent.had an unevent.ul recovery,and remains well and sympt.m-free at.18 mo *** is an ext.emely rare case of a pat.ent.wit. t.o synchro-nous somat.st.t.nomas of t.e duodenum and t.e *** condit.on is discussed wit. reference t. t.e lit.rat.re.

关键词： Somat.st.t.noma Duodenal neoplasms Pancreat.c neoplasms

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Seed Plant.Species Pools：t.e Development.of Species Richness in East.rn Asia and Nort. America

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生物多样性 1994年第B11期2卷 18-29页

作者： KENt.t. ADAIR SHIYOU LI henry M. Rockwell Professor of Forest.y henry M. Rockwell Post.oct.ral Fellow The Tucker Center Stephen F. Austin State University Nacogdoches Texas 75962 USA

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