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Journal of Integrative Agriculture 2013年第9期12卷 1551-1559页

作者： PENG Dian-liang CAI Tie YIN Yan-ping YANG Wei-bing NI Ying-li YANG Dong-qing WANG Zhen-lin National Key Laboratory of Crop Biology Shandong Agricultural University

Granule size distribution of wheat starch is an important characteristic that can affect its chemical composition and the functionality of wheat products. Two high-yield winter wheat cultivars were used to evaluate the effects of the application of exogenous ABA or ga during the reproductive phase of the initial grain filling on starch granule size distribution and starch components in grains at maturity. The results indicated that a bimodal curve was found in the volume and surface area distribution of grain starch granules, and a unimodal curve was observed for the number distribution under all treatments. The exogenous ABA resulted in a significant increase in the proportions （both by volume and by surface area） of B-type （〈9.9 Ixm in diameter） starch granules, with a reduction in those of A-type （〉9.9 ~tm） starch granules, while, the exogenous ga3 led to converse effects on size distribution of those starch granules. The exogenous ABA also increased starch, amylose and amylopectin contents at maturity but significantly reduced the ratio of amylose to amylopectin. Application of ga3 significantly reduced starch content, amylopectin content but increased the ratio of amylose to amylopectin. The ratio of amylose to amylopectin showed a significant and negative relationship with the volume proportion of granules 〈9.9 μm, but was positively related to the volume proportion of granules 22.8-42.8 μm.

关键词： abscisic acid gibberellin granule size distribution starch winter wheat (Triticum aestivum L.)

Identification of a novel gain-of-function mutant allele,slr1-d5,of rice DELLA protein

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Journal of Integrative Agriculture 2016年第7期15卷 1441-1448页

作者： ZHANG Yun-hui BIAN Xiao-feng ZHANG Suo-bing LING Jing WANG Ying-jie WEI Xiao-ying FANG Xian-wen The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm/Jiangsu Provincial Key Laboratory of Agrobiology/Institute of Food Crops Jiangsu Academy of Agricultural SciencesNanjing 210014P.R.China Shandong Business Institute Yantai 264670P.R.China

Controling the height of crops plays a crucial role for their yields. The large scale utilization of semi-dwarf varieties has greatly improved crop yield, providing an effective support for world food security. In rice, a main food for over half of the world’s population, a number of dwarf loci have been identiifed. However, most of them are recessive, such as the ‘green revolution’ genesd1. To gain more beneifcial loci for rice breeding programs, exploring new mutations is needed, especialy the dominant loci which can be used broadly for hybrid breeding. Here, we isolated a novel dominant dwarf rice mutant, slr1-d5. Al of the internodes ofslr1-d5are reduced. We ifnd that the responsiveness ofslr1-d5to gibberelin （ga）, ga3, was signiifcantly reduced. Map-based cloning revealed that the dominant dwarifsm ofslr1-d5was caused by an amino acid substitution in the N-terminal TVHYNP domain of rice DELLA protein, SLR1, where the conserved amino acid Pro （P） was substituted to His （H）. Our ifndings not only further prove the pivotal role of TVHYNP motif in regulating SLR1 stability, but also provide a new dwarf source for improvement of rice germplasms.

关键词： rice dominant dwarf DELLA protein gibberelin

Genome-wide antagonism between 5-hydroxymethylcytosine and DNA methylation in the adult mouse brain

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Frontiers in Biology 2014年第1期9卷 66-74页

作者： Junjie U. GUO Keith E. SZULWACH Yijing SU Yujing LI bing YAO Zihui XU Joo Heon SH1N bing XIE Yuan gaO Guo-li MING Peng JIN Hongjun SONG Institute for Cell Engineering Johns Hopkins University School of Medicine Baltimore MD 21205 USA The Solomon H. Snyder Department of Neuroscience Johns Hopkins University School of Medicine Baltimore MD 21205 USA Department of Neurology Johns Hopkins University School of Medicine Baltimore MD 21205 USA. Department of Human Genetics Emory University School of Medicine 615 Michael Street Atlanta GA 30322 USA Lieber Institute for Brain Development Johns Hopkins University School of Medicine Baltimore MD 21205 USA

Mounting evidence points to critical roles for DNA modifications, including 5-methylcytosine （5mC） and its oxidized forms, in the development, plasticity and disorders of the mammalian nervous system. The novel DNA base 5- hydroxymethylcytosine （5hmC） is known to be capable of initiating passive or active DNA demethylation, but whether and how extensively 5hmC functions in shaping the post-mitotic neuronal DNA methylome is unclear. Here we report the genome-wide distribution of 5hmC in dentate granule neurons from adult mouse hippocampus in vivo. 5hmC in the neuronal genome is highly enriched in gene bodies, especially in exons, and correlates with gene expression. Direct genome-wide comparison of 5hmC distribution between embryonic stem cells and neurons reveals extensive differences, reflecting the functional disparity between these two cell types. Importantly, integrative analysis of 5hmC, overall DNA methylation and gene expression profiles of dentate granule neurons in vivo reveals the genome-wide antagonism between these two states of cytosine modifications, supporting a role for 5hmC in shaping the neuronal DNA methylome by promoting active DNA demethylation.

关键词： dentate granule neuron active DNA demethylation TET methylome

Microstructure and giant baro-caloric effect induced by low pressure in Heusler Co_(51)Fe_(1)V_(33)ga_(15) alloy undergoing martensitic transformation

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Journal of Materials Science & Technology 2021年第14期73卷 76-82页

作者： Kai Liu Hai Zeng Ji Qi Xiaohua Luo Xuanwei Zhao Xianming Zheng Yuan Yuan Changcai Chen Shengcan Ma Ren Xie bing Li Zhenchen Zhong Jiangxi Key Laboratory for Rare Earth Magnetic Materials and Devices/Institute for Rare Earth Magnetic Materials and Devices(IREMMD) College of Rare EarthsJiangxi University of Science and TechnologyGanzhou341000China School of Materials Science and Engineering Faculty of Materials Metallurgy and ChemistryJiangxi University of Science and TechnologyGanzhou341000China Henan Key Laboratory of Photovoltaic Materials and School of Physics&Electronics Henan UniversityKaifeng475004China Shenyang National Laboratory(SYNL)for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefeiChina Guizhou Province Key Laboratory for Photoelectrics Technology and Application College of PhysicsGuizhou UniversityGuiyang550025China

Solid-state refrigeration based on the magneto-or mechano-caloric effect,including elasto-and barocaloric in ferroic phase transition materials is promising to replace the current vapor compression refrigeration in consideration of environmental-friendliness and ***,both high driven field and small thermal changes in all of these caloric materials hinder the development of solid-state *** we report a giant baro-caloric effect near room temperature induced by a low hydrostatic pressure in Co-based Co_(51)Fe_(1) V_(33)ga_(15) Heusler *** maximum adiabatic temperature change under the applied pressure change ofΔp=0.1-100 MPa can be as high asΔ_(Tad)^(Max)=7.7 K(Δ_(Tad)^(Max)/Δpreaches up to~7.7 K kbar-1),surpassing theΔ_(Tad)^(Max)/Δpvalue reported hitherto in baro-caloric *** addition,the microstructure is also studied by using the electron *** with the austenite and martensite,the submicron V-rich particles are precipitated in this alloy,which are believed to account for enhancing mechanical properties.

关键词： Solid-state refrigeration Barocaloric effect Adiabatic temperature change Isostatic pressure Martensitic transformation Co_(51)Fe_(1)V_(33)ga_(15)alloy

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马来酸酐改性高掺量橡胶沥青制备与性能

合成橡胶工业 2024年第3期47卷 197-202页

作者：张子轮景杰张国杰王寒冰王仕峰上海交通大学化学化工学院上海200240 甘肃公航旅建设集团有限公司兰州730000

使用高度降解的再生橡胶(DR)制备了高掺量橡胶沥青(HCRA),通过衰减全反射傅里叶变换红外光谱仪、凝胶渗透色谱仪、动态剪切流变仪和动态力学分析仪,对比研究了马来酸酐(MAH)预接枝DR改性与MAH和DR直接共混改性对HCRA结构与性能的影响,... 详细信息

使用高度降解的再生橡胶(DR)制备了高掺量橡胶沥青(HCRA),通过衰减全反射傅里叶变换红外光谱仪、凝胶渗透色谱仪、动态剪切流变仪和动态力学分析仪,对比研究了马来酸酐(MAH)预接枝DR改性与MAH和DR直接共混改性对HCRA结构与性能的影响,探讨了两种改性方法的改性机理。结果表明,MAH预接枝DR时发生了由烯烃双键和烯丙基碳氢原子提供活性位点的自由基取代反应,而MAH和DR与沥青直接共混时,存在自由基取代反应和酯化反应两种反应,并以后者为主;MAH改性HCRA的溶胶组分中以中低分子量组分为主;MAH改性显著改善了HCRA的高、低温流变性能。此外,两种改性方法对HCRA的结构与性能均有影响,且随MAH掺量的变化存在明显差异。

关键词：马来酸酐再生橡胶高掺量橡胶沥青接枝反应改性反应机理高低温性能

A High Performance In_(0.7)ga_(0.3)As MOSFET with an InP Barrier Layer for Radio-Frequency Application

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Chinese Physics Letters 2013年第3期30卷 143-145页

作者： CHANG Hu-Dong LIU Gui-Ming SUN bing ZHAO Wei WANG Wen-Xin LIU Hong-gang Microwave Device and IC Department Institute of MicroelectronicsChinese Academy of SciencesBeijing 100029 Institute of Physics Chinese Academy of SciencesBeijing 100190

We demonstrate a high performance implant-free n-type In_(0.7)ga_(0.3)As channel MOSFET with a 4-nm InP barrier layer fabricated on a semi-insulating substrate employing a 10-nm Al_(2)O_(3) as gate *** maximum effective channel mobility is 1862 cm^(2)/V·s extracted by the split C–V *** with 0.8μm gate length exhibit a peak extrinsic transconductance of 85 mS/mm and a drive current of more than 200 mA/mm.A short-circuit current gain cutoff frequency f_(T) of 24.5 GHz and a maximum oscillation frequency f_(max) of 54 GHz are achieved for the 0.8μm gate-length *** research is helpful to obtain higher performance In_(0.7)ga_(0.3)As MOSFETs for radio-frequency applications.

关键词： channel InP dielectric

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基于架构搜索的雷达回波降雨强度分类算法

信息技术 2024年第10期48卷 1-6页

作者：柴怡君陆冰鉴陆振宇颜诗洋南京信息工程大学人工智能学院南京210000 法国国家信息与自动化研究所法国巴黎75020

天气雷达是降雨监测的重要手段,基于天气雷达降雨回波特征实现准确的降雨强度分类至关重要。文中提出了基于3D注意力模块的CNN(EA-CNN)进化搜索算法,算法利用遗传算法(ga)自动搜索最优结构,快速优化CNN架构的宽度与深度,准确找到最佳CN... 详细信息

天气雷达是降雨监测的重要手段,基于天气雷达降雨回波特征实现准确的降雨强度分类至关重要。文中提出了基于3D注意力模块的CNN(EA-CNN)进化搜索算法,算法利用遗传算法(ga)自动搜索最优结构,快速优化CNN架构的宽度与深度,准确找到最佳CNN结构,具有很强的泛化能力。算法引入3D注意力模块有效抑制分类中的干扰像素问题,能够准确提取各强度降雨特征,帮助相关人士从雷达回波中快速获取降雨分级结果。实验表明,与4种经典的算法(KNN、SVM、VGG、ResNet12)相比,所提出的算法在人力、物力等成本上更具竞争性,分类准确率提升7.95%。

关键词：卷积神经网络(CNN) 神经架构搜索(NAS) 雷达降雨强度遗传算法(ga) 3D注意力模块

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基于混合优化算法的分块镜共相位误差校正

光学学报 2015年第11期35卷 104-110页

作者：孙雪董冰北京理工大学光电学院北京100081

对采用分块拼接式主镜的大口径空间望远镜,有必要研究适合在轨应用的共相位误差校正方法。以像清晰度函数作为评价函数,通过仿真分析了单色光和白光照明2种情况下分块镜共相位误差与评价函数的变化关系。仿真结果表明:采用单色光照明时... 详细信息

对采用分块拼接式主镜的大口径空间望远镜,有必要研究适合在轨应用的共相位误差校正方法。以像清晰度函数作为评价函数,通过仿真分析了单色光和白光照明2种情况下分块镜共相位误差与评价函数的变化关系。仿真结果表明:采用单色光照明时,分块镜平移误差校正的动态范围小于0.5λ;采用白光照明时,评价函数存在局部极值,必须采用全局最优化算法。仿真结果表明,当平移误差大于0.5λ时,采用随机并行梯度下降(SPGD)算法易陷入局部极值,而采用遗传算法(ga)可以搜索到全局最优解,但迭代速度较慢。提出了采用基于SPGD算法和遗传算法的混合优化算法校正分块镜共相位误差。当平移误差在[-λ,+λ]范围内时,混合优化算法的校正精度可优于10 nm。

关键词：成像系统自适应光学分块镜共相位误差混合优化算法随机并行梯度下降遗传算法

Risk stratification of hemodynamically significant patent ductus arteriosus by clinical and genetic factors

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World Journal of Pediatrics 2023年第12期19卷 1192-1202页

作者： Yu-Xi Chen Tian-Tian Xiao Hui-Yao Chen Xiang Chen Ya-Qiong Wang Qi Ni bing-bing Wu Hui-Jun Wang Yu-Lan Lu Li-Yuan Hu Yun Cao Guo-Qiang Cheng Lai-Shuan Wang Fei-Fan Xiao Lin Yang Xin-Ran Dong Wen-Hao Zhou Center for Molecular Medicine of Children’s Hospital of Fudan University Institutes of Biomedical SciencesFudan University138 Yi Xue Yuan RoadShanghaiChina Department of Neonatology Children’s Hospital of Fudan UniversityNational Children’s Medical CenterShanghaiChina Center for Molecular Medicine Children’s Hospital of Fudan University399 Wanyuan RoadShanghai201102China

Background Hemodynamically significant patent ductus arteriosus(hsPDA)is associated with increased comorbidities in *** evaluation of hsPDA risk is critical to implement individualized *** aim of the study was to provide a powerful reference for the early identification of high-risk hsPDA population and early treatment *** We enrolled infants who were diagnosed with PDA and performed exome *** collapsing analyses were used to find the risk gene set(RGS)of hsPDA for model *** credibility of RGS was proven by RNA *** logistic regression was performed to establish models combining clinical and genetic *** models were evaluated by area under the receiver operating curve(AUC)and decision curve analysis(DCA).Results In this retrospective cohort study of 2199 PDA patients,549(25.0%)infants were diagnosed with *** model[all clinical characteristics selected by least absolute shrinkage and selection operator regression(all CCs)]based on six clinical variables was acquired within three days of life,including gestational age(ga),respiratory distress syndrome(RDS),the lowest platelet count,invasive mechanical ventilation,and positive inotropic and vasoactive *** has an AUC of 0.790[95%confidence interval(CI)=0.749–0.832],while the simplified model(basic clinical characteristic model)including ga and RDS has an AUC of 0.753(95%CI=0.706–0.799).There was a certain consistency between RGS and differentially expressed genes of the ductus arteriosus in *** AUC of the models was improved by RGS,and the improvement was significant(all CCs *** CCs+RGS:0.790 vs.0.817,P<0.001).DCA demonstrated that all models were clinically *** Models based on clinical factors were developed to accurately stratify the risk of hsPDA in the first three days of *** features might further improve the model performance.

关键词： Exome sequencing-Hemodynamically significant patent ductus arteriosus Multivariate logistic regression Neonates Risk stratification

The Reaction Of Metal Trialkyls With Benzo[H]Quinolin-10-ol

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Chinese Chemical Letters 1999年第10期10卷 875-878页

作者： Xue Song WU Hong Sui SUN Yi PAN Hua bing CHEN Xiang Zhen SUN(Department of Chemistry, Nanjing University, Nanjing 210093) Department of Chemistry Nanjing University Nanjing 210093 China

The reaction of the trialkyl metals (R3M, R = Me, Et; M = ga, In) with benzo[h]quinolin-10-ol (HO-BQ) in a 1:1 molar ratio gave intramolecular N coordinated complexes R2M-O-BQ (M = ga, R = Me 1, Et 2) and (R2In-O-BQ)(2) (M = In, R = Et 3,) in 80-90% yield. The molecular structures of complexes 1 and 3 have been established by X-ray crystallography.

关键词： metal trialkyls gallium indium MOCVD precursors X-ray crystal structure