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Genetic Diversity Caused by Environmental Stress in Natural Populations of Niupidujuan as Revealed by RAPD Technique

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Chemical Research in Chinese Universities 2011年第4期27卷 641-645页

作者： DU Ying-da XING Ming yanG Zhi-yong LIU yan-fei chen Xia College of Life Science Jilin University Changchun 130012 P. R. China

Multiplex environmental factors are generally expected to have significant effects on genetic diversity of plant *** this study,randomly amplified polymorphic DNA（RAPD） technique was used to reveal the genetic diversity in the same species of four populations collected from Niupidujuan（Rhododendron chrysanthum） at different altitudes,an endangered species,endemic to Northeast ***,twenty informative and reproducible primers were chosen for final RAPD analysis.A total of 152 clear bands were obtained,including 143 polymorphic *** the help of POPGENE software,the poly rate was calculated to be 94.07% and the evenness of amplified bands for every primer was ***,the mean observed number of alleles was 1.7265 with an effective number of *** examination of the gene indicated a diversity of 0.2162 with an information diversity index of *** these data,the clustering blurred analysis was performed with the aid of NTSYS-pc software to define the Nei＇s gene diversity and the Shannon information diversity index of the four plant *** relationships between the genetic diversity indexes on the one hand and the geographic and climatic factors on the other hand were estimated by the Pearson correlation with SPSS 11.0 *** results of the correlation analysis show that there were significant（P〈0.05） or highly significant（P〈0.01） correlations between each of the genetic diversity indexes and the different temperature which were mainly caused by the altitude different populations *** data highlight the importance of native populations in shaping the spatial genetic structure in Niupidujuan.

关键词： Environmental stress Genetic diversity Randomly amplified polymorphic DNA(RAPD) Clustering blurred analysis

The role of intestinal microbiota,bile acids,and Th17/IL17 axis in hepatitis B virus-related liver fibrosis

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Chinese Medical Journal 2020年第24期133卷 2902-2904页

作者： yan-fei chen Jiu chen Lan-Juan Li State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesDepartment of Infectious DiseasesThe First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhouZhejiang 310003China Department of Traditional Chinese Medicine The First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhouZhejiang 310003China

Hepatitis B virus(HBV)infection,which affects 90 million people in China,remains a prominent cause of liver cancer and liver cirrhosis.[1]Chronic HBV infection has a complicated course,which is a dynamic process formed by the interaction between the virus and the immune system.[2,3]Hepatic fibrosis is the basis of liver cirrhosis and liver cancer.[4]In recent years,accumulating studies have indicated potential roles of intestinal microbiota,bile acids,and T helper(Th)17/interleukin(IL)-17 axis in the process of HBV-related liver *** microbiota actively communicates with bile acids and plays an important role in the pathogenesis of HBV-related liver *** the following content,we are going to summarize current evidence of the role of intestinal microbiota,bile acids,and Th17/IL-17 axis in HBV-related liver fibrosis.

关键词： Th17 bile IL17

Synergistic Performance Management System and Its Associated Structural Model

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Journal of Systems Science and Information 2009年第3期7卷 261-267页

作者： Xiaoyong Luo Gang Du Rui yan fei chen School of Management Tianjin University Tianjin 300072 China

Aiming at the widespread issues of synergistic performance management, a conceptual model of synergistic performance management system is built. The order parameter of system synergy and the main factors, as well as the degree of synergy and the concept of synergistic effect are proposed. An associated structural model of synergistic performance management system is established based on the method of structural equation modeling.

关键词： synergy performance management order parameter degree of synergy synergistic effect

Calmodulin regulates the post-anaphase reposition of centrioles during cytokinesis

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Cell Research 2005年第7期15卷 548-552页

作者： Yue Yue YU, Gu DAI, fei yan PAN, Jie chen, Chao Jun LI*Jiangsu Key Laboratory for Molecular & Medical Biotechnology, School of Life Sciences, Nanjing Normal University.Nanjing 210097, China Jiangsu Key Laboratory for Molecular & Medical Biotechnology School of Life Sciences Nanjing Normal University Nanjing China

A transient postanaphase repositioning of the centriole is found to control the completion of cytokinesis. Using agreen fluorescent protein-calmodulin fusion protein as a living cell probe, we have previously found that calmodulin isassociated with the initiation and progression of cytokinesis. In this study, we further studied the effect of calmodulinon the repositioning of the centriole and subsequent cell cycle progression. When activity of calmodulin is inhibited, theregression of the centriole from the intercellular bridge to the cell center is blocked, and thus the completion of celldivision is repressed and two daughter cells are linked by longer cell bridge in perturbed cells. W7 treatment duringcytokinesis also results in unfinished cytokinesis and stopped G1 phase. These results suggest that calmodulin activity isrequired for centriole repositioning and can affect the completion of cytokinesis and cell cycle progression.

关键词： CaM centriole reposition cytokinesis W7.

Numerical magnitude processing in abacus-trained children with superior mathematical ability: an EEG study

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2015年第8期16卷 661-671页

作者： Jian HUANG Feng-lei DU Yuan YAO Qun WAN Xiao-song WANG fei-yan chen Bio-X Laboratory Department of Physics Zhejiang University Department of Psychology and Behavioral Sciences Zhejiang University Heilongjiang Abacus Association

Distance effect has been regarded as the best established marker of basic numerical magnitude processes and is related to individual mathematical abilities. A larger behavioral distance effect is suggested to be concomitant with lower mathematical achievement in children. However, the relationship between distance effect and superior mathematical abilities is unclear. One could get superior mathematical abilities by acquiring the skill of abacus-based mental calculation （AMC）, which can be used to solve calculation problems with exceptional speed and high accuracy. In the current study, we explore the relationship between distance effect and superior mathematical abilities by examining whether and how the AMC training modifies numerical magnitude processing. Thus, mathematical competencies were tested in 18 abacus-trained children （who accepted the AMC training） and 18 non-trained children. Electroencephalography （EEG） waveforms were recorded when these children executed numerical comparison tasks in both Arabic digit and dot array forms. We found that：（a） the abacus-trained group had superior mathematical abilities than their peers; （b） distance effects were found both in behavioral results and on EEG wave- forms; （c） the distance effect size of the average amplitude on the late negative-going component was different between groups in the digit task, with a larger effect size for abacus-trained children; （d） both the behavioral and EEG distance effects were modulated by the notation. These results revealed that the neural substrates of magnitude processing were modified by AMC training, and suggested that the mechanism of the representation of numerical magnitude for children with superior mathematical abilities was different from their peers. In addition, the results provide evidence for a view of non-abstract numerical representation.

关键词： Electroencephalography (EEG) Abacus training Distance effect Numerical magnitude processing Child

Structures and Photoluminescent Properties of the Lanthanide Coordination Polymers with Carboxylate Ligand

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Structures and Photoluminescent Properties of the Lanthanide...

Human adenovirus(HAdV)infection in children with acute respiratory tract infections in Guangzhou,China,2010–2021:a molecular epidemiology study

中国化学会第九届全国无机化学学术会议

作者： fei-yan chen Zhen Liu Yun-Long Feng Zhejiang Key Laboratory for Reactive Chemistry on Solid Surfaces College of Chemistry and Life ScienceZhejiang Normal University

A series of lanthanide（Ⅲ）metal-organic coordination polymers[Ln（L）（H2O）2]·Solvent{Ln=Pr（1）,Sm（2）,Eu（3）,Gd（4）,Tb（5）,Dy（6）,Ho（7）}{H3L=5-（6-carboxynaphthalen-2-yl）isophtahalic acid}have been synthesized by reacting the corresponding rare earth salts with 5-（6-carboxynaphthalen-2-yl）isophtahalic acid under solvothermal *** polymers have been characterized by single crystal X-ray diffraction,IR spectrum,thermogravimetric analyses（TGA）,and X-ray powder diffraction.X-ray single crystal diffraction analyses reveal that all polymers are isostructural with a three-dimensional（3D）*** 1-7 are nine-coordinated with distorted tricapped trigonalprism geometry around each metal *** dinuclear units in 1-7 form the one-dimensional helix chain and furtherextend to three-dimensional framework with rectangular channels through bridged by H3L *** complexs of Eu（Ⅲ）exhibit the corresponding characteristic luminescence[1-2]in the visible region at an excitation of 390 nm.

关键词： 5-(6-carboxynaphthalen-2-yl) isophtahalic acid lanthanide coordination polymers photoluminescent properties

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World Journal of Pediatrics 2022年第8期18卷 545-552页

作者： Yi chen Tao Lin Chang‑Bing Wang Wan‑Li Liang Guang‑Wan Lian Mark Zanin Sook‑San Wong Xin‑Gui Tian Jia‑Yu Zhong Ying‑Ying Zhang Jia‑Hui Xie Ling‑Ling Zheng fei‑yan chen Run Dang Ming‑Qi Zhao Yi‑Yu yang Rong Zhou Bing Zhu Center Laboratory Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangzhou 510120China State Key Laboratory of Respiratory Diseases Guangzhou Institute of Respiratory HealthGuangzhou Medical UniversityGuangzhouChina Intensive Care Unit Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangzhou 510120China Guangzhou Medical University Guangzhou 510120China

Background Human adenovirus(HAdV)infection can cause a variety of *** is a major pathogen of pediatric acute respiratory tract infections(ARIs)and can be life-threatening in younger *** described the epidemiology and subtypes shifting of HAdV among children with ARI in Guangzhou,*** We conducted a retrospective study of 161,079 children diagnosed with acute respiratory illness at the Guangzhou Women and Children’s Medical Center between 2010 and *** specimens were detected by real-time PCR and the hexon gene was used for phylogenetic *** Before the COVID-19 outbreak in Guangzhou,the annual frequency of adenovirus infection detected during this period ranged from 3.92%to 13.58%,with an epidemic peak every four to fve *** demonstrated a clear seasonal distribution,with the lowest positivity in March and peaking during summer(July or August)every year.A signifcant increase in HAdV cases was recorded for 2018 and 2019,which coincided with a shift in the dominant HAdV subtype from HAdV-3 to *** latter was associated with a more severe disease compared to *** average mortality proportion for children infected with HAdV from 2016 to 2019 was 0.38%but increased to 20%in severe *** COVID-19 emerged,HAdV cases dropped to 2.68%,suggesting that non-pharmaceutical interventions probably reduced the transmission of HAdV in the *** Our study provides the foundation for the understanding of the epidemiology of HAdV and its associated risks in children in Southern China.

关键词： Acute respiratory tract infection Children Human adenovirus Severe acute hepatitis Southern China

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膜式水冷壁传热边界条件反演

中国电机工程学报 2012年第5期32卷 93-98页

作者：蒋文萍王广军严飞陈红低品位能源利用技术及系统教育部重点实验室(重庆大学) 重庆市沙坪坝区400044

膜式水冷壁传热边界条件对现代电站锅炉安全运行有重要影响。针对其难以直接测量的现状,采用共轭梯度法对膜式水冷壁的传热边界条件进行了反演,并讨论了测点数目、待反演参数的初始猜测值及测量误差对反演结果及向火侧金属外壁温度分布... 详细信息

膜式水冷壁传热边界条件对现代电站锅炉安全运行有重要影响。针对其难以直接测量的现状,采用共轭梯度法对膜式水冷壁的传热边界条件进行了反演,并讨论了测点数目、待反演参数的初始猜测值及测量误差对反演结果及向火侧金属外壁温度分布的影响。结果表明:增加测点数可提高反演精度,而3个测点即可达到较高精度;反演结果对初值有一定的依赖性;在一定的测量误差范围内,共轭梯度法仍能够得到较满意的结果。

关键词：膜式水冷壁传热边界条件共轭梯度法传热反问题

Morphology engineering of ZnO micro/nanostructures under mild conditions for optoelectronic application

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 498-503页

作者： Liang Chu Haoyu Shen Hudie Wei Hongyu chen Guoqiang Ma Wensheng yan Institute of Carbon Neutrality and New Energy&School of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China School of Applied Physics and Materials Wuyi UniversityJiangmen 529020China

Zinc oxide(ZnO)serves as a crucial functional semiconductor with a wide direct bandgap of approximately 3.37 *** reaction is commonly used in the synthesis of ZnO micro/nanostructures,given its low cost,simplicity,and easy ***,ZnO morphology engineering has become desirable through the alteration of minor conditions in the reaction process,particularly at room *** this work,ZnO micro/nanostructures were synthesized in a solution by varying the amounts of the ammonia added at low temperatures(including room temperature).The formation of Zn^(2+)complexes by ammonia in the precursor regulated the reaction rate of the morphology engineering of ZnO,which resulted in various structures,such as nanoparticles,nanosheets,microflowers,and single ***,the obtained ZnO was used in the optoelectronic application of ultraviolet detectors.

关键词： morphology engineering low temperature ZnO nanosheets microflowers ultraviolet detector