检索结果-南通市图书馆

A mitochondria-targeted H_(2)S-activatable fluorogenic probe for tracking hepatic ischemia-reperfusion injury

Chinese Chemical Letters 2024年第6期35卷 370-375页

作者： Bin fang Jiaqi Yang Limin Wang Haoqin Li Jiaying Guo Jiaxin Zhang Qingyuan Guo Bo Peng Kedi Liu Miaomiao Xi hua Bai Li Fu lin Li School of Materials Science and Engineering Northwestern Polytechnical UniversityXi’an 710072China Frontiers Science Center for Flexible Electronics Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Key laboratory of Flexible Electronics of Zhejiang Province Ningbo Institute of Northwestern Polytechnical UniversityNingbo 315103China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen 361005China Wuhan National Laboratory for Optoelectronics-Advanced Biomedical Imaging Facility Huazhong University of Science and TechnologyWuhan 430074China TANK Medicinal Biology Institute of Xi’an Xi’an 710032China

Hepatic ischemia-reperfusion injury(HIRI)is the cause of postoperative hepatic dysfunction and failure,and even *** an important biological effector molecule,hydrogen sulfide(H_(2)S)of mitochondria as a gasotransmitter that is usually used to protect against acute HIRI ***,the exact relationship between HIRI and mitochondrial H_(2)S remains tangled due to the lack of an effective analytical ***,we have fabricated a mitochondria-targeted H_(2)S-activatable fluorogenic probe(Mito-GW)to explore the stability of mitochondrial H_(2)S and track the changes of mitochondrial H_(2)S during the *** virtue of pyridinium electropositivity and its amphiphilicity,Mito-GW could accumulate in *** goes through an analyte-prompted immolation when reacts with H_(2)S,resulting in the releasing of the fluorophore(GW).Therefore,the extent of Mito-GW conversion to GW can be used to evaluate the changes of mitochondrial H_(2)S level in living cells and *** proof-of-principle,we have used MitoGW to demonstrate the mitochondria H_(2)S-levels increase and then decrease during HIRI in vitro and in *** research highlights the tremendous potential of Mito-GW as a mitochondrial H_(2)S fluorogenic probe in elucidating the pathogenesis of HIRI,providing a powerful tool for promoting future research on hepatology.

关键词： Mitochondria-targeted Bioimaging H2S-activatable Fluorogenic probe Hepatic ischemia-reperfusion injury(HIRI)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fracture network types revealed by well test curves for shale reservoirs in the Sichuan Basin,China

引用

Energy Geoscience 2024年第1期5卷 264-274页

作者： Yanyan Wang hua Liu Xiaohu Hu Cheng Dai Sidong fang State Key Laboratory of Shale Oil and Gas Enrichment Mechanisms and Effective Development Petroleum Exploration and Development Research InstituteSinopecBeijing100083China

Pressure buildup testing can be used to analyze fracture network characteristics and conduct quantitative interpretation of relevant parameters for shale gas wells,thus providing bases for assessing the well productivity and formulating proper development *** study establishes a new well test interpretation model for fractured horizontal wells based on seepage mechanisms of shale reservoirs and proposes a method for identifying fracturing patterns based on the characteristic slopes of pressure buildup curves and curve combination *** pressure buildup curve patterns are identified to represent three types of shale reservoirs in the Sichuan Basin,namely the moderately deep shale reservoirs with high pressure,deep shale reservoirs with ultra-high pressure,and moderately deep shale reservoirs with normal *** on this,the relationship between the typical pressure buildup curve patterns and the fracture network types are put *** effects of three types of shale gas reservoir are compared and *** results show that typical flow patterns of shale reservoirs include bilinear flow in primary and secondary fractures,linear flow in secondary fractures,bilinear flow in secondary fractures and matrix,and linear flow in *** fracture network characteristics can be determined using the characteristic slopes of pressure buildup curves and curve *** linear flow in early secondary fractures is increasingly distinct with an increase in primary fracture ***,the bilinear flow in secondary fractures and matrix and the subsequent linear flow in the matrix occur as the propping and density of secondary fractures *** increase in the burial depth,in-situ stress,and stress difference corresponds to a decrease in the propping of primary fractures that expand along different directions in the shale gas wells in the Sichuan *** pressure buildup curve patterns exist in the Sichuan Basin and it

关键词： Shale gas Fractured horizontal well Well testing interpretation Flow pattern characterization Parameter inversion Fracture network characteristics Sichuan basin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaluation of suitability,adaptability,and reserve potential of construction land on the Qinghai-Tibet Plateau

引用

Journal of Geographical Sciences 2024年第1期34卷 41-61页

作者： YANG hua XU Yong ZHOU Kan WANG Lijia XU lin Key Laboratory of Regional Sustainable Development Modeling Institute of Geographic Sciences and Natural Resources ResearchCASBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China

Construction land is the leading carrier of human activities such as production and *** the construction land suitability(CLS)on the Qinghai-Tibet Plateau(QTP)holds significant implications for harmonizing the relationship between ecological protection and human activity and promoting population and industry layout ***,no relevant studies provide a complete CLS assessment of the *** this study,we developed a model-based CLS evaluation framework coupling of pattern and process to calculate the global CLS on the QTP based on a previously developed CLS evaluation ***,using the land-use data of 1990,2000,2010,and 2020,we examined the adaptability of existing construction land(ECL)to the CLS assessment result through the adaptability index and vertical gradient index and further analyzed the limitations of maladaptive construction ***,we calculated the potential area of reserve suitable construction *** article includes four conclusions:(1)The highly suitable,suitable,moderately suitable,marginally suitable,and unsuitable CLS classes cover areas of 0.33×10^(4)km^(2),10.42×10^(4)km^(2),18.06×10^(4)km^(2),24.12×10^(4)km^(2),and 205.29×10^(4)km^(2),*** approximately 11%of the study area on the QTP is suitable for large-scale permanent construction land,and approximately 79.50%of the area is unsuitable under current economic and technological conditions.(2)The ECL adaptability index is 85.16%,85.93%,85.18%,and 78.01%during 1990–2020,respectively,with an average adaptability index exceeding 80%on the *** ECL distribution generally conforms to construction land suitable space characteristics but with a significant spatial difference.(3)From 1990 to 2020,the maladaptive ECL was dominated by rural settlement land,transport land,and special land,with a rapidly increasing proportion of urban and other construction *** maladaptive ECL is constrained by both elevation and slope in the southern Qinghai Pla

关键词： land resource construction land suitability existing construction land adaptability human activity Qinghai-Tibet Plateau

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tetraphenylethene-based hole transporting material for highly efficient and stable perovskite solar cells

引用

Science China Chemistry 2024年第6期67卷 2009-2015页

作者： Peng Wang Pei Yuan Chenghao Ge Rongjun Zhao lin Xie Yong hua School of Materials and Energy Yunnan UniversityKunming650091China

2,2,7,7-Tetrakis-(N,N-di-p-methoxyphenylamine)-9,9-spirobifluorene(Spiro-OMeTAD)has been identified as the most widely used and effective hole transporting material(HTM)in perovskite solar cells(PSCs).However,the complicated multistep synthesis and low intrinsic hole mobility of Spiro-OMe TAD limit its commercialized ***,developing highly efficient HTMs with less synthetic steps becomes increasingly ***,understanding hot carriers transfer dynamics at the interface of perovskite layer and hole transport layer is crucial for further enhancing PSCs performance towards Shockley-Queisser limit,which still lacks full investigation to ***,a new HTM based on tetraphenylethene(WP1)was successfully synthesized by a simple one-step reaction *** was found that WP1-based HTM exhibits more matched energy level,higher hole mobility and conductivity than those of the control Spiro-OMe *** femtosecond transient absorption results reveal that the transfer rate of hot holes in perovskite/WP1 sample is four times higher than that of perovskite/Spiro-OMeTAD,thereby helping enhance the device ***,the efficiency of PSCs is enhanced to 24.04%(WP1)from 22.85%(Spiro-OMeTAD).Moreover,the un-encapsulated device prepared with WP1 exhibits better long-term stability,retaining 87%of its initial PCE value after storing for 72 days under air environment,while the reference device shows76%of its initial *** work indicates that simple tetraphenylethene-based organic small molecule could be a very promising HTM candidate for highly efficient PSCs,and gives some significant insights for understanding intrinsic hot carriers transfer dynamics in device.

关键词： tetraphenylethene hole transporting material perovskite solar cells mobility hot carrier

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Salinity effect-induced ENSO amplitude modulation in association with the interdecadal Pacific Oscillation

引用

Journal of Oceanology and Limnology 2024年第4期42卷 1019-1036页

作者： Hai ZHI Xiaokun WANG Rong-hua ZHANG Pengfei lin Jifeng QI College of Atmospheric Sciences Nanjing University of Information Science and TechnologyNanjing 210044China School of Marine Sciences Nanjing University of Information Science and TechnologyNanjing 210044China Laoshan Laboratory Qingdao 266237China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric Physics(IAP)Chinese Academy of SciencesBeijing 100029China Key Laboratory of Ocean Circulation and Waves Institute of Oceanologyand Center for Ocean Mega-ScienceChinese Academy of SciencesQingdao 266071China

A 110-year ensemble simulation of an ocean general circulation model(OGCM)was analyzed to identify the modulation of salinity interdecadal variability on El Niño-Southern Oscillation(ENSO)amplitude in the tropical Pacific during *** simulating results show that sea surface salinity(SSS)variation in the region exhibits notable and coherent interdecadal variability signal,which is closely associated with the Interdecadal Pacific Oscillation(IPO).As salinity increases or reduces,the SSS modulations on ENSO amplitude during its warm/cold events vary asymmetrically with positive/negative IPO ***,salinity interdecadal variability can enhance or reduce ENSO-related conditions in upper-ocean stratification,contributing noticeably to ENSO *** anomalies associated with the mixed layer depth and barrier layer thickness can modulate ENSO amplitude during positive and negative IPO phases,resulting in the asymmetry of sea surface temperature(SST)anomaly in the tropical *** positive IPO phases,SSS interdecadal variability contributes positively to El Niño amplitude but negatively to La Niña amplitude by enhancing or reducing SSS interannual variability,and vice versa during negative IPO ***,the results indicate that the modulation of the ENSO amplitude by the SSS interdecadal variability is 15%-28%during negative IPO phases and 30%-20%during positive IPO phases,***,the SSS interdecadal variability associated with IPO and its modulation on ENSO amplitude in the tropical Pacific are among factors essentially contributing ENSO diversity.

关键词： El Niño-Southern Oscillation(ENSO)amplitude Interdecadal Pacific Oscillation(IPO) ocean salinity variability tropical Pacific upper-ocean stratification

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gigahertz-rate-switchable wavefront shaping through integration of metasurfaces with photonic integrated circuit

引用

Advanced Photonics 2024年第1期6卷 106-114页

作者： Haozong Zhong Yong Zheng Jiacheng Sun Zhizhang Wang Rongbo Wu ling-en Zhang Youting Liang Qinyi hua Minghao Ning Jitao Ji Bin fang lin Li Tao Li Ya Cheng Shining Zhu East China Normal University School of Physics and Electronic ScienceState Key Laboratory of Precision SpectroscopyShanghaiChina Nanjing University College of Engineering and Applied SciencesNational Laboratory of Solid State MicrostructuresNanjingChina China Jiliang University College of Optical and Electronic TechnologyHangzhouChina Shanxi University Collaborative Innovation Center of Extreme OpticsTaiyuanChina Chinese Academy of Sciences(CAS) Shanghai Institute of Optics and Fine Mechanics(SIOM)State Key Laboratory of High Field Laser Physics and CAS Center for Excellence in Ultra-Intense Laser ScienceShanghaiChina

Achieving spatiotemporal control of light at high speeds presents immense possibilities for various applications in communication,computation,metrology,and *** integration of subwavelength metasurfaces and optical waveguides offers a promising approach to manipulate light across multiple degrees of freedom at high speed in compact photonic integrated circuit(PIC)***,we demonstrate a gigahertz-rate-switchable wavefront shaping by integrating metasurface,lithium niobate on insulator photonic waveguides,and electrodes within a PIC *** proofs of concept,we showcase the generation of a focus beam with reconfigurable arbitrary polarizations,switchable focusing with lateral focal positions and focal length,orbital angular momentum light beams as well as Bessel *** measurements indicate modulation speeds of up to the gigahertz *** integrated platform offers a versatile and efficient means of controlling the light field at high speed within a compact system,paving the way for potential applications in optical communication,computation,sensing,and imaging.

关键词： metasurface photonic integrated circuit lithium niobate on insulator high-speed modulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synergistic catalysis of the N-hydroxyphthalimide on flower-like bimetallic metal-organic frameworks for boosting oxidative desulfurization

引用

Petroleum Science 2024年第1期21卷 674-682页

作者： Jing He Kun Zhu Wei Jiang Dong-Ao Zhu lin-hua Zhu Hai-Yan huang Wen-Shuai Zhu hua-Ming Li Institute for Energy Research Jiangsu UniversityZhenjiang212013JiangsuChina College of Chemistry and Chemical Engineering Hainan Normal UniversityKey Laboratory of Water Pollution Treatment and Resource Reuse of Hainan ProvinceHaikou571158HainanChina

Synergic catalytic effect between active sites and supports greatly determines the catalytic activity for the aerobic oxidative desulfurization of fuel *** this work,Ni-doped Co-based bimetallic metal-organic framework(CoNi-MOF)is fabricated to disperse N-hydroxyphthalimide(NHPI),in which the whole catalyst provides plentiful synergic catalytic effect to improve the performance of oxidative desulfurization(ODS).As a bimetallic MOF,the second metal Ni doping results in the flower-like morphology and the modification of electronic properties,which ensure the exposure of NHPI and strengthen the synergistic effect of the overall *** with the monometallic Co-MOF and naked NHPI,the NHPI@CoNi-MOF triggers the efficient activation of molecular oxygen and improves the ODS performance without an *** sulfur removal of dibenzothiophene-based model oil reaches 96.4%over the NHPI@CoNi-MOF catalyst in 8 h of ***,the catalytic product of this aerobic ODS reaction is sulfone,which is adsorbed on the catalyst surface due to the difference in *** work provides new insight and strategy for the design of a strong synergic catalytic effect between NHPI and bimetallic supports toward high-activity aerobic ODS materials.

关键词： Metal-organic frameworks Doped Bimetallic N-hydroxyphthalimide Aerobic processes Oxidative desulfurization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

More than just aligning the teeth:Clear aligners with multifunctional prowess

引用

Nano Research 2024年第8期17卷 7665-7674页

作者： Yang Chen Lei-Ming Cao Nian-Nian Zhong Zi-Zhan Li lin-lin Bu fang-Yi Huo Hong He State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration Key Laboratory of Oral Biomedicine Ministry of EducationHubei Key Laboratory of StomatologySchool and Hospital of StomatologyWuhan UniversityWuhan 430079China Department of Oral and Maxillofacial-Head Neck Oncology School and Hospital of StomatologyWuhan UniversityWuhan 430079China Department of Zhuankou Clinical Branches School and Hospital of StomatologyWuhan UniversityWuhan 430000China Department of Orthodontics School and Hospital of StomatologyWuhan UniversityWuhan 430079China

With the increasing demand for beauty and health,clear aligners(CAs)have been widely applied among patients with ***,patients treated with CAs also face some potential complications,such as demineralization,dental caries,and periodontal *** addition,some patients have additional needs to improve their quality of life,such as bleaching *** order to prevent or solve these problems,the modification of CAs is a promising method because their extensive long-term contact with tooth surfaces makes them ideal devices for implementing adjuvant medical *** this review,we discuss various advanced CAs with medical functions based on the clinical needs of *** far as we know,the additional functions of CAs mainly include antibacterial,remineralization,whitening,and accelerating tooth *** functions are achieved by two major pathways,the combination of CAs with drugs/biomaterials and increasing the capacity or affinity of *** addition,we discuss the current limitations of in vitro experiments which are designed to explore the effectiveness and properties of novel CAs,and the challenges of bringing a multifunctional appliance from proposal to clinical *** the end of this review,we provide insights into the broader prospects for the improvement of CAs.

关键词： advanced clear aligners medical device modification drug delivery system personalized medicine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cr-assisted low-temperature densification of(Ti,Zr,Nb,Ta,Mo)C high-entropy carbides with ultrafine grain and enhanced hardness

引用

Journal of Advanced Ceramics 2024年第6期13卷 780-788页

作者： Yang Liu Jiaji Liang Weiming Guo Shikuan Sun Yu Tian hua-Tay lin School of Electromechanical Engineering Guangdong University of TechnologyGuangzhou 510006China State Key Laboratory of High Performance Tools Guangdong University of TechnologyGuangzhou 510006China School of Material Science and Energy Engineering Foshan UniversityFoshan 528000China

While the use of low-melting-point metals as sintering aids for high-entropy carbide(HEC)ceramics has been well established,their existence can compromise hardness due to residual metallic *** study demonstrates an innovative strategy to meet this challenge,where(Ti,Zr,Nb,Ta,Mo)C high-entropy carbide ceramics with ultrafine grains and enhanced hardness are obtained through chromium(Cr)-metal-assisted spark plasma sintering(SPS)at a temperature as low as 1600℃.The results show that the addition of 5 vol%Cr promotes the formation of highly densified single HEC phase ceramics with a high relative density(98.4%)and an ultrafine-grained microstructure(0.17μm).This low-temperature densification mechanism can be attributed to Cr’s solid-solution effect within the matrix and the increased carbon vacancies generated during *** grain size of the(Ti,Zr,Nb,Ta,Mo)C ceramics with 5 vol%Cr metal addition is significantly smaller than that of Cr-free(Ti,Zr,Nb,Ta,Mo)C ceramics sintered at 2000℃(3.03μm)or via traditional low-temperature liquid-phase sintering(1.3–1.5μm).Importantly,the addition of 5 vol%Cr substantially increased the hardness of the ceramics,with a remarkable increase from 23.57 to 28.16 GPa compared to that of the pure(Ti,Zr,Nb,Ta,Mo)C ceramics,owing to the fine-grain strengthening and solid-solution strengthening *** work highlights the uniqueness of Cr metal as a sintering aid in achieving densification and hardness improvements in(Ti,Zr,Nb,Ta,Mo)C ceramics,offering a promising strategy for improving the properties of HEC materials for further development in the near future.

关键词： solid solution sinterability hardness enhancement (Ti,Zr,Nb,Ta,Mo)C high-entropy carbide(HEC)ceramics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sub-Seasonal Predictability of the Northeast China Cold Vortex in BCC and ECMWF S2S Model Forecasts for 2006-2021

引用

Journal of Meteorological Research 2024年第3期38卷 453-468页

作者： Yiqiu YU Jie WU Yihe fang Chunyu ZHAO Zongjian KE Yitong lin Liaoning Provincial Climate Centre Liaoning Provincial Meteorological AdministrationShenyang110166China Key Opening Laboratory for Northeast China Cold Vortex Research China Meteorological AdministrationShenyang110166China Panjin National Climate Observatory Panjin124000China China Meteorological Administration Key Laboratory for Climate Prediction Studies National Climate CentreChina Meteorological AdministrationBeijing100081China Jilin Provincial Climate Centre Jilin Provincial Meteorological AdministrationChangchun130062China

As an important atmospheric circulation system in the mid-high latitudes of East Asia,the Northeast China cold vortex(NCCV)substantially influences weather and climate in this *** far,systematic assessment on the performance of numerical prediction of the NCCVs has not been carried *** on the Beijing Climate Centre(BCC)and the ECMWF model hindcast and forecast data that participated in the Sub-seasonal to Seasonal(S2S)Prediction Project,this study systematically examines the performance of both models in simulating and forecasting the NCCVs at the sub-seasonal *** results demonstrate that the two models can effectively capture the seasonal variations in the intensity,active days,and spatial distribution of NCCVs;however,the duration of NCCVs is shorter and the intensity is weaker in the models than in the *** analysis shows that the differences in the intensity and location of the East Asian subtropical westerly jet and the wave train pattern from North Atlantic to East Asia may be responsible for the deficient simulation of NCCV events in the S2S ***,in the deterministic forecasts,BCC and ECMWF provide skillful prediction on the anomalous numbers of NCCV days and intensity at a lead time of 4-5(5-6)pentads,and the skill limit of the ensemble mean is 1-2 pentads longer than that of individual *** the probabilistic forecasts of daily NCCV activities,BCC and ECMWF exhibit a forecasting skill of approximately 7 and 11 days,respectively;both models show seasonal dependency in the simulation performance and forecast skills of NCCV events,with better performance in winter than in *** results from this study provide helpful references for further improvement of the S2S prediction of NCCVs.

关键词： Northeast China cold vortex(NCCV) predictability sub-seasonal to seasonal(S2S)prediction deterministic forecast probabilistic forecast

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：