More than just aligning the teeth:Clear aligners with multifunctional prowess
作者机构：State Key Laboratory of Oral and Maxillofacial Reconstruction and RegenerationKey Laboratory of Oral Biomedicine Ministry of EducationHubei Key Laboratory of StomatologySchool and Hospital of StomatologyWuhan UniversityWuhan 430079China Department of Oral and Maxillofacial-Head Neck OncologySchool and Hospital of StomatologyWuhan UniversityWuhan 430079China Department of Zhuankou Clinical BranchesSchool and Hospital of StomatologyWuhan UniversityWuhan 430000China Department of OrthodonticsSchool and Hospital of StomatologyWuhan UniversityWuhan 430079China
出 版 物：《Nano Research》 (纳米研究（英文版）)
年 卷 期：2024年第17卷第8期
页 面：7665-7674页
核心收录：
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1007[医学-药学(可授医学、理学学位)] 100706[医学-药理学] 1003[医学-口腔医学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 10[医学]
基 金：supported by Postdoctoral Science Foundation of China(Nos.2018M630883 and 2019T120688) Hubei Province Chinese Medicine Research Project(No.ZY2023Q015) Natural Science Foundation of Hubei Province(No.2023AFB665)
主 题：advanced clear aligners medical device modification drug delivery system personalized medicine
摘 要：With the increasing demand for beauty and health,clear aligners(CAs)have been widely applied among patients with ***,patients treated with CAs also face some potential complications,such as demineralization,dental caries,and periodontal *** addition,some patients have additional needs to improve their quality of life,such as bleaching *** order to prevent or solve these problems,the modification of CAs is a promising method because their extensive long-term contact with tooth surfaces makes them ideal devices for implementing adjuvant medical *** this review,we discuss various advanced CAs with medical functions based on the clinical needs of *** far as we know,the additional functions of CAs mainly include antibacterial,remineralization,whitening,and accelerating tooth *** functions are achieved by two major pathways,the combination of CAs with drugs/biomaterials and increasing the capacity or affinity of *** addition,we discuss the current limitations of in vitro experiments which are designed to explore the effectiveness and properties of novel CAs,and the challenges of bringing a multifunctional appliance from proposal to clinical *** the end of this review,we provide insights into the broader prospects for the improvement of CAs.
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