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Managements of osteoporotic vertebral compression fractures:A narrative review

World Journal of Orthopedics 2022年第6期13卷 564-573页

作者： devon patel Jiayong Liu Nabil A Ebraheim College of Medicine and Life Sciences University of ToledoToledoOH 43614United States Department of Orthopedic Surgery University of Toledo Medical CenterToledoOH 43614United States

Osteoporotic vertebral compression fractures(OVCFs)are the most common fragility fracture and significantly influence the quality of life in the ***,the literature lacks a comprehensive narrative review of the management of *** purpose of this study is to review background information,diagnosis,and surgical and non-surgical management of the OVCFs.A comprehensive search of PubMed and Google Scholar for articles in the English language between 1980 and 2021 was *** of the following terms were used:compression fractures,vertebral compression fractures,osteoporosis,osteoporotic compression fractures,vertebroplasty,kyphoplasty,bisphosphonates,calcitonin,and osteoporosis *** articles were also included by examining the reference list of articles found in the ***,especially those that occur over long periods,can be *** of acute OVCFs include pain localized to the mid-line spine,a loss in height,and decreased *** primary treatment regimens are pain control,medication management,vertebral augmentation,and anterior or posterior decompression and *** control can be achieved with acetaminophen or nonsteroidal anti-inflammatory drugs for mild pain or opioids and/or calcitonin for moderate to severe *** and denosumab are the first-line treatments for *** and kyphoplasty are reserved for patients who have not found symptomatic relief through conservative methods and are effective in achieving pain *** is less technical and cheaper than kyphoplasty but could have more *** and vitamin D supplementation can have a protective and therapeutic *** of OVCFs must be combined with multiple *** exercises and activity modification are important in fracture *** with different mechanisms of action is a critical long-term causal treatment *** minimall

关键词： Vertebral body Osteoporosis Fragility fractures Osteoporotic vertebral compression fractures Kyphoplasty Vertebroplasty

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Influence of cardiorespiratory fitness and body composition on resting and post-exercise indices of vascular health in young adults

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Sports Medicine and Health Science 2024年第1期6卷 54-62页

作者： Rian Q.Landers-Ramos Kathleen Dondero Ian Imery Nicholas Reveille Hannah A.Zabriskie devon A.Dobrosielski Towson University Department of KinesiologyTowsonMDUSA University of Maryland School of Medicine Department of Physical Therapy and Rehabilitation SciencesBaltimoreMDUSA Johns Hopkins University Department of Cell BiologyBaltimoreMDUSA University of Florida Department of Applied Physiology and KinesiologyGainesvilleFLUSA

Poor cardiorespiratory fitness may mediate vascular impairments at rest and following an acute bout of exercise in young healthy *** study aimed to compare flow mediated dilation(FMD)and vascular augmentation index(AIx75)between young adults with low,moderate,and high levels of cardiorespiratory fitness before and after an acute bout of aerobic ***-three participants(22 men;21 women)between 18 and 29 years of age completed the *** were classified into low,moderate,and high health-related cardiorespiratory fitness groups according to age-and sex-based relative maximal oxygen consumption(V_O2 max)percentile *** was performed using Doppler ultrasound and AIx75 was performed using pulse wave analysis at baseline and 60-min after a 30-min bout of treadmill running at 70%V_O2 max.A significant interaction(p=0.047;ηp 2=0.142)was observed,with the moderate fitness group exhibiting a higher FMD post-exercise compared with baseline([6.7%3.1%]vs.[8.5%2.8%],p=0.028;d=0.598).We found a significant main effect of group for AIx75(p=0.023;ηp 2=0.168),with the high fitness group exhibiting lower AIx75 compared to low fitness group([10%10%]vs.[2%10%],respectively,p=0.019;g=1.07).This was eliminated after covarying for body fat percentage(p=0.489).Our findings suggest that resting FMD and AIx75 responses are not significantly influenced by cardiorespiratory fitness,but FMD recovery responses to exercise may be enhanced in individuals with moderate cardiorespiratory fitness levels.

关键词： Cardiorespiratory fitness Flow mediated dilation Augmentation index Vascular Acute exercise Body composition

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Forecasting tropical cyclone coastal and marine hazards and impacts

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Tropical Cyclone Research and Review 2024年第1期13卷 1-14页

作者： Nadao Kohno Cody Fritz Monica Sharma Robbie Berg Diana Greenslade devon Telford Sakeasi Rabitu P.L.N.Murty M.Mohapatra Maria Cristina C.Uson Japan Meteorological Agency TokyoJapan National Hurricane Center MiamiUSA India Meteorological Department New DelhiIndia Bureau of Meteorology MelbourneAustralia Environment and Climate Change Canada QuebecCanada Fiji Meteorological Service NadiFiji Philipine Atmospheric Geophysical and Astronomical Services AdministrationQuezon CityPhilippines

The report highlights the signiﬁcant progress over various regions with respect to understanding of coastal hazards,numerical modeling techniques and the generation&dissemination of coastal hazard warnings and *** developments over various regions in the globe during 2014–18 have been discussed in this report as presented during 10th Session of International Workshop on Tropical Cyclones(IWTC-X)at Bali,*** speciﬁcally,various regions have started to confront the uncertainty that cannot be removed from TC analyses and forecasts and further communicate those hazards within the context of risk[probabilistic]based *** also includes impact-based forecasts such as communicating coastal inundation information relative to total water level instead of storm surge,speciﬁcally(i.e.,anomaly from as-tronomical tide and waves).Lastly,updates to model grid conﬁguration,model resolution,and coupled dynamical systems continue to resolve the costal hazards more *** approaches have likely helped reduce loss of life relative to historical ***,regions agree that the generation and dissemination of coastal hazard information still need to be improved in view of growing population along the coast and thus increased exposure of life to coastal hazard.

关键词： Coastal inundation Storm surge Probabilistic forecast

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Burial and exhumation history of the Xigaze forearc basin, Yarlung suture zone. Tibet

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Geoscience Frontiers 2019年第3期10卷 895-908页

作者： devon A.Orme Department of Earth Sciences Montana State University

The Cretaceous-Eocene Xigaze forearc basin is a crucial data archive for understanding the tectonic history of the Asian continental margin prior to and following collision with India during the early Cenozoic Era. This study reports apatite and zircon(U-Th)/He thermochronologic data from fourteen samples from Albian-Ypresian Xigaze forearc strata to determine the degree and timing of heating(burial) and subsequent cooling(exhumation) of two localities along the Yarlung suture zone(YSZ) near the towns of Saga and Lazi. Thirty-seven individual zircon He ages range from 31.5 ± 0.8 Ma to6.06 ± 0.18 Ma,with the majority of grains yielding ages between 30 Ma and 10 Ma. Twenty apatite He ages range from 12.7 ± 0.5 Ma to 3.9 ± 0.3 Ma,with the majority of grains yielding ages between 9 Ma and 4 Ma. These ages suggest that the Xigaze forearc basin was heated to 140-200 ℃ prior to cooling in Oligocene-Miocene time. Thermal modeling supports this interpretation and shows that the samples were buried to maximum temperatures of ～140-200 0 C by 35-21 Ma, immediately followed by the onset of exhumation. The zircon He and apatite He dataset and thermal modeling results indicate rapid exhumation from ～21 Ma to 15 Ma, and at ～4 Ma. The 21-15 Ma thermochronometric signal appears to be regionally extensive, affecting all the lithotectonic units of the YSZ, and coincides with movement along the north-vergent Great Counter Thrust system. Thrusting, coupled with enhanced erosion possibly related to the paleo-Yarlung River, likely drove Early Miocene cooling of the Xigaze forearc *** contrast, the younger phase of rapid exhumation at ～4 Ma was likely driven by enhanced rock uplift in the footwall of north-striking rifts that cross-cut the YSZ.

关键词： Xigaze Tibet Forearc basin Thermochronology Yarlung

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Patterns of reproductive isolation in the Drosophila subquinaria complex： can reinforced premating isolation cascade to other species？

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Current Zoology 2016年第2期62卷 183-191页

作者： devon P. HUMPHREYS Howard D. RUNDLE Kelly A. DYER Department of Genetics University of Georgia Athens GA 30602 USA Department of Biology University of Ottawa Ottawa ON K1N 6N5 Canada

The reinforcement of premating barriers due to reduced hybrid fitness in sympatry may cause secondary sexual isolation within a species as a by-product. Consistent with this, in the fly Drosophila subquinaria, females that are sympatric with D. recens mate at very low rates not only with D. recens, but also with conspecific D. subquinaria males from allopatry. Here, we ask if these effects of re- inforcement cascade more broadly to affect sexual isolation with other closely related species. We assay reproductive isolation of these species with D. transversa and find that choosy D. subquinaria females from the region sympatric with D. recens discriminate strongly against male D. transversa, whereas D. subquinaria from the allopatric region do not. This increased sexual isolation cannot be explained by natural selection to avoid mating with this species, as they are allopatric in geographic range and we do not identify any intrinsic postzygotic isolation between D. subquinaria and D. transversa. Variation in epicuticular hydrocarbons, which are used as mating signals in D. subquinaria, follow patterns of premating isolation： D. transversa and allopatric D. subquinaria are most similar to each other and differ from sympatric D. subquinaria, and those of D. recens are distinct from the other two species. We suggest that the secondary effects of reinforcement may cascade to strengthen reproductive isolation with other species that were not a target of selection. These effects may enhance the divergence that occurs in allopatry to help explain why some species are already sexually isolated upon secondary contact.

关键词： epicuticular hydrocarbons hybrid sterility mate choice reinforcement speciation Wolbachia

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Parallel droplet microfluidics for high throughput cell encapsulation and synthetic microgel generation

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Microsystems & Nanoengineering 2018年第1期4卷 525-533页

作者： devon M.Headen JoséR.García Andrés J.García Woodruff School of Mechanical Engineering Georgia Institute of TechnologyAtlantaGA 30332USA Petit Institute for Bioengineering and Biosciences Georgia Institute of TechnologyAtlantaGA 30332USA

Cells can be microencapsulated in synthetic hydrogel microspheres(microgels)using droplet microfluidics,but microfluidic devices with a single droplet generating geometry have limited throughput,especially as microgel diameter *** we demonstrate microencapsulation of human mesenchymal stem cells(hMSCs)in small(o100μm diameter)microgels utilizing parallel droplet generators on a two-layer elastomer device,which has 600% increased throughput ***-nozzle *** of microgel diameters were compared between products of parallel ***-nozzle configurations for two square nozzle widths,35 and 100μ*** produced on parallel nozzles were equivalent to those produced on single nozzles,with substantially the same *** of hMSCs was compared for parallel nozzle devices of each *** five micrometer wide nozzle devices could be operated at twice the cell concentration of 100μm wide nozzle devices but produced more empty microgels than predicted by a Poisson *** micrometer wide nozzle devices produced microgels as predicted by a Poisson *** of microgels did not increase with the addition of cells for either nozzle *** encapsulated on 35μm wide nozzle devices had reduced viability(~70%)and a corresponding decrease in vascular endothelial growth factor(VEGF)secretion compared to hMSCs cultured on tissue culture(TC)*** hMSCs using 100μm wide nozzle devices mitigated loss of viability and function,as measured by VEGF secretion.

关键词： droplets microencapsulation microgel multilayer parallel

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Who Is the Best

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中小学外语教学（下半月） 2007年第2期30卷 48-48,F0003页

作者： devon 韩红北京市育鸿学校

人物：C—Crocodile E—ElephantG—Giraffe K—KangarooL—LionP—PenguinT—Tourist

关键词：剧场儿童人物道具

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Escapades in the East

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The World of Chinese 2012年第4期 94-95页

作者： devon HSIAO.G9.BCIS

The World of Chinese Creative Narrative Contest was created to build a bridge among international school students in Beijing,with an aim to promote creativity among native or international high school students based on their experiences living in *** contestants for the“My China”writing contest were all students from grades 8 to 12 at Beijing City International School

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Review of Infrared Detector Technology

Review of Infrared Detector Technology

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International Conference on Millimeter Wave and far-Infrared Technology

作者： devon G.Crowe Center for Optical Science and Engineering and Director Electromagnetics Laboratory Ceorgia Institute of Technology Atlanta Georgia 30332

＜正＞ This paper will review selected infrared detectors which offer （or have the potential to offer） the best signal-to-noise ratio achievable for some application. It is not, therefore, the intent to exhaustively review all types of infrared detectors. Future directions for progress in infrared detector performance will be covered.

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Inferior outcomes of liver transplantation for hepatocellular carcinoma during early-COVID-19 pandemic in the United States

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World Journal of Hepatology 2023年第4期15卷 554-563页

作者： Inkyu S Lee Kenji Okumura Ryosuke Misawa Hiroshi Sogawa Gregory Veillette devon John Thomas Diflo Seigo Nishida Abhay Dhand Department of Surgery Westchester Medical CenterValhallaNY 10595United States Department of Medicine Westchester Medical CenterValhallaNY 10595United States

BACKGROUND Early in the coronavirus disease 2019(COVID-19)pandemic,there was a significant impact on routine medical care in the United States,including in fields of transplantation and *** To analyze the impact and outcomes of early COVID-19 pandemic on liver transplantation(LT)for hepatocellular carcinoma(HCC)in the United *** WHO declared COVID-19 as a pandemic on March 11,*** retrospectively analyzed data from the United Network for Organ Sharing(UNOS)database regarding adult LT with confirmed HCC on explant in 2019 and *** defined pre-COVID period from March 11 to September 11,2019,and early-COVID period as from March 11 to September 11,*** Overall,23.5%fewer LT for HCC were performed during the COVID period(518 vs 675,P<0.05).This decrease was most pronounced in the months of March-April 2020 with a rebound in numbers seen from May-July *** LT recipients for HCC,concurrent diagnosis of non-alcoholic steatohepatitis significantly increased(23 vs 16%)and alcoholic liver disease(ALD)significantly decreased(18 vs 22%)during the COVID *** age,gender,BMI,and MELD score were statistically similar between two groups,while waiting list time decreased during the COVID period(279 days vs 300 days,P=0.041).Among pathological characteristics of HCC,vascular invasion was more prominent during COVID period(P<0.01),while other features were the *** the donor age and other characteristics remained same,the distance between donor and recipient hospitals was significantly increased(P<0.01)and donor risk index was significantly higher(1.68 vs 1.59,P<0.01)during COVID *** outcomes,90-day overall and graft survival were the same,but 180-day overall and graft were significantly inferior during COVID period(94.7 vs 97.0%,P=0.048).On multivariable Coxhazard regression analysis,COVID period emerged as a significant risk factor of post-transplant mortality(Hazard ratio 1.85;95%CI:1.28-2.68,P=0.001).CONCLUSION Durin

关键词： Liver transplantation Hepatocellular carcinoma COVID-19 Mortality Graft failure United Network for Organ Sharing database

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