Managements of osteoporotic vertebral compression fractures:A narrative review

作     者：Devon Patel Jiayong Liu Nabil A Ebraheim 

作者机构：College of Medicine and Life SciencesUniversity of ToledoToledoOH 43614United States Department of Orthopedic SurgeryUniversity of Toledo Medical CenterToledoOH 43614United States 

出 版 物：《World Journal of Orthopedics》 (世界骨科杂志（英文版）)

年 卷 期：2022年第13卷第6期

页      面：564-573页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Vertebral body Osteoporosis Fragility fractures Osteoporotic vertebral compression fractures Kyphoplasty Vertebroplasty 

摘      要：Osteoporotic vertebral compression fractures(OVCFs)are the most common fragility fracture and significantly influence the quality of life in the ***,the literature lacks a comprehensive narrative review of the management of *** purpose of this study is to review background information,diagnosis,and surgical and non-surgical management of the OVCFs.A comprehensive search of PubMed and Google Scholar for articles in the English language between 1980 and 2021 was *** of the following terms were used:compression fractures,vertebral compression fractures,osteoporosis,osteoporotic compression fractures,vertebroplasty,kyphoplasty,bisphosphonates,calcitonin,and osteoporosis *** articles were also included by examining the reference list of articles found in the ***,especially those that occur over long periods,can be *** of acute OVCFs include pain localized to the mid-line spine,a loss in height,and decreased *** primary treatment regimens are pain control,medication management,vertebral augmentation,and anterior or posterior decompression and *** control can be achieved with acetaminophen or nonsteroidal anti-inflammatory drugs for mild pain or opioids and/or calcitonin for moderate to severe *** and denosumab are the first-line treatments for *** and kyphoplasty are reserved for patients who have not found symptomatic relief through conservative methods and are effective in achieving pain *** is less technical and cheaper than kyphoplasty but could have more *** and vitamin D supplementation can have a protective and therapeutic *** of OVCFs must be combined with multiple *** exercises and activity modification are important in fracture *** with different mechanisms of action is a critical long-term causal treatment *** minimall