Influence of cardiorespiratory fitness and body composition on resting and post-exercise indices of vascular health in young adults

作     者：Rian Q.Landers-Ramos Kathleen Dondero Ian Imery Nicholas Reveille Hannah A.Zabriskie Devon A.Dobrosielski 

作者机构：Towson UniversityDepartment of KinesiologyTowsonMDUSA University of Maryland School of MedicineDepartment of Physical Therapy and Rehabilitation SciencesBaltimoreMDUSA Johns Hopkins UniversityDepartment of Cell BiologyBaltimoreMDUSA University of FloridaDepartment of Applied Physiology and KinesiologyGainesvilleFLUSA 

出 版 物：《Sports Medicine and Health Science》 (运动医学与健康科学（英文）)

年 卷 期：2024年第6卷第1期

页      面：54-62页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：approved by the Towson University Institutional Review Board(IRB#1810041426) study was registed on Clinical Trials.gov public website(NCT06163456) 

主　　题：Cardiorespiratory fitness Flow mediated dilation Augmentation index Vascular Acute exercise Body composition 

摘      要：Poor cardiorespiratory fitness may mediate vascular impairments at rest and following an acute bout of exercise in young healthy *** study aimed to compare flow mediated dilation(FMD)and vascular augmentation index(AIx75)between young adults with low,moderate,and high levels of cardiorespiratory fitness before and after an acute bout of aerobic ***-three participants(22 men;21 women)between 18 and 29 years of age completed the *** were classified into low,moderate,and high health-related cardiorespiratory fitness groups according to age-and sex-based relative maximal oxygen consumption(V_O2 max)percentile *** was performed using Doppler ultrasound and AIx75 was performed using pulse wave analysis at baseline and 60-min after a 30-min bout of treadmill running at 70%V_O2 max.A significant interaction(p=0.047;ηp 2=0.142)was observed,with the moderate fitness group exhibiting a higher FMD post-exercise compared with baseline([6.7%3.1%]vs.[8.5%2.8%],p=0.028;d=0.598).We found a significant main effect of group for AIx75(p=0.023;ηp 2=0.168),with the high fitness group exhibiting lower AIx75 compared to low fitness group([10%10%]vs.[2%10%],respectively,p=0.019;g=1.07).This was eliminated after covarying for body fat percentage(p=0.489).Our findings suggest that resting FMD and AIx75 responses are not significantly influenced by cardiorespiratory fitness,but FMD recovery responses to exercise may be enhanced in individuals with moderate cardiorespiratory fitness levels.