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Outcome of meniscal r.pair. in paediatr.c population:A ter.iar. centr. exper.ence

作者： (美)david r. hanson

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Wor.d Jour.al of Or.hopedics 2024年第6期15卷 547-553页

作者： Ayman Gabr.Samson Williams Sophie Dodd Nick Bar.on-hanson Depar.ment of Tr.uma&Or.hopaedics West Suffolk HospitalSuffolk IP332QZUnited Kingdom Depar.ment of Tr.uma and Or.hopaedics Alder Hey Children's HospitalLiverpool L145ABUnited Kingdom

BACKGr.UND Meniscal spar.ng sur.er. is a widely utilised tr.atment option for.unstable meniscal tear. with the aim of minimising the r.sk of pr.gr.ssion towar.s ***,ther. is limited data in the liter.tur. on meniscal r.pair.outcomes in skeletally immatur. *** To evaluate the r.-oper.tion r.te and functional outcomes of meniscal r.pair. in childr.n and *** We per.or.ed a r.tr.spective r.view of all patients who under.ent ar.hr.scopic meniscal r.pair.sur.er. between Januar. 2007 and Januar. *** patients wer. under.the age of 18 at the time of *** wer. all per.or.ed by a single *** was gather.d fr.m our.hospital Electr.nic Patient r.cor.s *** pr.mar. outcome measur. was r.-oper.tion r.te(need for.fur.her.sur.er. on the same meniscus).Secondar. outcome measur.s wer. sur.ical complications and patient r.por.ed outcome measur.s that wer. Inter.ational Knee Documentation Committee(IKDC),Tegner.and Lysholm *** We identified 59 patients who under.ent 66 All-inside meniscal r.pair.(32 medial meniscus and 34 Later.l meniscus).Meniscal r.pair. wer. per.or.ed utilizing FasT-Fix(Smith and Nephew)*** wer. 37 males and 22 females with an aver.ge age of 14 year.(r.nge 6-16).The aver.ge follow-up time was 53 months(r.nge 26-140).Six patients had concomitant anter.or.cr.ciate ligament r.constr.ction sur.er. along with the meniscal *** wer. no r.quir.ng fur.her.meniscal r.pair. and 9 patients under.ent par.ial *** mean postoper.tive IKDC scor. was 88(44-100),Tegner.scor. was 7(2-10)and Lysholm scor. was 94(57-100).CONCLUSION Our.r.sults showed that ar.hr.scopic r.pair.of meniscal tear. in the paediatr.c population is an effective tr.atment option that has a low failur. r.te and good postoper.tive clinical with the advantage of pr.ser.ing meniscal tissues.

关键词： Meniscus Meniscal r.pair Outcome Meniscal pr.ser.ation

A Myosin XI Tail Domain Homologous to the Yeast Myosin Vacuole-Binding Domain Inter.cts with Plastids and Str.mules in Nicotiana benthamiana

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Molecular.Plant 2009年第6期2卷 1351-1358页

作者： Amir.Sattar.adeh Johanna Kr.hmer.Ar.aud D. Ger.ain Maur.en r. hanson Depar.ment of Molecular.Biology and Genetics Biotechnology Building Cornell University Ithaca NY 14853 USA

The actin cytoskeleton plays a r.le in mobility of many differ.nt or.anelles in plant cells, including chlor.plasts, mitochondr.a, Golgi, and per.xisomes. While pr.gr.ss has been made in identifying the myosin motor. involved in tr.fficking of var.ous plant or.anelles, not all of the car.oes mobilized by differ.nt member. of the myosin XI family have yet been identified. The involvement of myosins in chlor.plast positioning and mitochondr.al movement was demonstr.ted by expr.ssion of a vir.s-induced gene silencing （VIGS） constr.ct in tobacco. When VIGS with two differ.nt conser.ed sequences fr.m a myosin Xl motor.was per.or.ed in plants with either.GFP-labeled plastids or.mitochondr.a, chlor.plast positioning in the dar. was abnor.al, and mitochondr.al movement ceased. Because these and pr.or.obser. vations have implicated a r.le for.myosins and the actin cytoskeleton in plastid and str.mule movement, we sear.hed for.myosin tail domains that could associate with plastids and str.mules. While a yellow fluor.scent pr.tein （YFP） fusion with the entir. tail r.gion of myosin XI-F was usually found only in the cytoplasm, we obser.ed that an Ar.bidopsis or.Nicotiana benthamiana YFP：：myosin XI-F tail domain homologous to the yeast myo2p vacuole-binding domain associated with plastids and str.mules after.tr.nsient expr.ssion in N. benthamiana. Taken together. these obser.ations implicate myosin motor.pr.teins in dynamics of plastids and str.mules.

关键词： Chlor.plast biology cytoskeleton dynamics mitochondr.a gene silencing fluor.scent pr.tein.

Evaluating the quality of feed fats and oils and their.effects on pig gr.wth per.or.ance

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Jour.al of Animal Science and Biotechnology 2016年第3期7卷 330-340页

作者： Ger.ld C Shur.on Br.an J Ker. Andr.a r.hanson Depar.ment of Animal Science University of MinnesotaStPaulMN 55018USA usda-ar.-national labor.tor. for.agr.cultur. and the envir.nment Ames IA 50011USA svc-r.sear.h St PeterMN 56082USA

Feed fats and oils pr.vide significant amounts of ener.y to swine diets, but ther. is lar.e var.ation in composition,quality, feeding value, and pr.ce among sour.es. Common measur.s of lipid quality include moistur., insolubles,and unsaponifiables（MIU）, titer. and fr.e fatty acid content, but pr.vide limited infor.ation r.gar.ing their.feeding value. Lipid per.xidation is an impor.ant quality factor.r.lated to animal gr.wth per.or.ance and health, but maximum toler.ble limits in var.ous lipids have not been established. Sever.l indicative assays can be used to detect the pr.sence of var.ous per.xidation compounds, but due to the complexity and numer.us compounds pr.duced and degr.ded dur.ng per.xidation pr.cess, no single method can adequately deter.ine the extent of per.xidation. Until fur.her.infor.ation is available, using a combination of per.xide value, thiobar.itur.c acid r.active substances（TBAr.）, and anisidine value appear.to pr.vide a r.asonable assessment of the extent of per.xidation in a lipid at a r.asonable cost. However. fatty acid composition of the lipid being evaluated should be consider.d when selecting specific assays. Pr.dictive tests can also be used to estimate the stability or.susceptibility of lipids to per.xidation and include active oxygen method, oil stability index, and oxygen bomb method. A r.view of 16 published studies with pigs has shown an aver.ge decr.ase of 11.4% in gr.wth r.te, 8.8% feed intake fed isocalor.c diets containing per.xidized lipids compar.d to diets containing unper.xidized lipids of the same ***, ser.m vitamin E content was gener.lly r.duced and ser.m TBAr. content was incr.ased when per.xidized lipids wer. fed in these studies, suggesting that feeding per.xidized lipids negatively affects metabolic oxidative status of pigs. However. it is unclear.if antioxidants ar. useful additions to lipids to maintain optimal nutr.tional value, or.if their.addition to swine diets is beneficial in over.oming a met

关键词： Gr.wth Indicative tests Lipids Metabolic oxidation Per.xidation Pigs

Chinese Sour.es for.After.ar.s:Fr.m Pr.moder. Poetr.,Paintings,and Medical Texts to Moder. Novels,Film,and Documentar.es

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Chinese Medicine and Cultur. 2023年第2期6卷 127-138页

作者： Mar.a hanson Independent Scholar Max Planck Institute for the History of ScienceBerlin 14195Germany

This paper.focuses on Chinese sour.es suggested for.a nar.ative medicine(NM)pr.gr.m,called *** Laur.n Small established After.ar.s in 2014 and has been coor.inating it since out of the Pediatr.cs Depar.ment at Johns Hopkins *** ear.y 2019,she star.ed giving a ser.es of lectur.s and wor.shops about After.ar.s to Chinese medical educator. and clinicians in Beijing and *** cr.ated an After.ar.s Facilitator.s Guide based on Wester.-language sour.es for.wor.shop *** also star.ed to or.anize with Jiang Yuhong(Peking Union Medical College)a wor.shop for.Chinese colleagues to be held at Johns Hopkins Medicine in October.*** invited the author.to *** idea was hatched then to develop Chinese sour.e mater.als following the After.ar.s str.ctur. for.an updated Facilitator.s Guide that Dr.Small had initially wr.tten.A typical one-hour.After.ar.s session consists of a specific five-par. str.ctur.:a liter.r. text or.ar.wor.,an associated theme,discussion topics,a wr.ting exer.ise,and shar.d *** the content of the pr.gr.m always changes fr.m session to session,the basic str.ctur. r.mains the *** paper.summar.zes the types of Chinese sour.es and their.r.lated nar.ative-medicine themes that wer. or.ginally selected for.inclusion in the updated After.ar.s Facilitator.s Guide intended for.Chinese *** sour.es about coping with sick family member.,aging,and illness r.nged fr.m the textual(classical Chinese poems on aging and diagnostic for.s for.tr.ining students)and visual(pr.moder. Chinese paintings and mur.ls of medical encounter.)to the fictive(novels)and per.or.ative(contempor.r. Asian-Amer.can film in English and Chinese-language film and documentar.es).

关键词： Documentar.es Films Mur.ls Nar.ative medicine Novels Paintings Poetr.

Gr.sping Heaven and Ear.h(Qian Kun Zai Wo):The Body-as-Technology in Classical Chinese Medicine

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中医药文化(英文) 2023年第3期6卷 233-246页

作者： Mar.a hanson Independent Scholar Affiliate Max Planck Institute for the History of ScienceBerlin 14195Germany

Shifting focus fr.m the patient’s body to the healer.s body,this essay focuses on how Chinese physicians instr.mentalized their.bodies to heal(ie,body-as-technology)and their.hands to think with(ie,hand-memor. techniques or.simply,hand mnemonics).When physicians used their.hands to memor.ze concepts r.lated to clinical pr.ctice,calculate with time var.ables,and car.y out r.tual gestur.s intended to r.duce r.sk,impr.ve for.une,and even cur.,their.hands became extensions of their.*** essay has thr.e par.s that follow the discover. pr.cess of the author.s r.sear.h on hand-memor. techniques found in Chinese medical *** fir.t par.“Divination and r.velation”explains the significance of how the author.fir.t lear.ed about Chinese divination pr.ctices that used hand *** second par.“Or.ginal Fr.me”intr.duces the scholar.hip on ar.s of memor. in Eur.pe that infor.ed inter.r.tations of the ear.iest hand mnemonics found in Chinese medical *** thir. par.“Expanded Fr.me”deploys some concepts fr.m cognitive science to help situate Chinese medical hand mnemonics mor. br.adly as an example of extended *** essay concludes with an impor.ant distinction:sometimes Chinese healer.’hands wer. used separ.tely fr.m their.bodies to think thr.ugh things and sometimes hand and body had to be integr.ted in or.er.for.the healer.s body-as-technology to act as a ther.peutically effective instr.ment.

关键词： Ar.s of memor. Body-as-technology Extended cognition Hand mnemonics

Olfactor. r.ceptor.gene evolution is unusually r.pid acr.ss Tetr.poda and outpaces chemosensor. phenotypic change

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Cur.ent Zoology 2020年第5期66卷 505-514页

作者： Laur.l r.Yohe Matteo Fabbr. Michael hanson Bhar.-Anjan S.Bhullar Depar.ment of Ear.h&Planetar. Science Peabody Museum of Natural HistoryYale UniversityNew HavenCT06511USA

Chemosensation is the most ubiquitous sense in animals,enacted by the pr.ducts of complex gene families that detect envir.nmental chemical cues and lar.er.scale sensor. str.ctur.s that pr.cess these *** ther. is a gener.l conception that olfactor. r.ceptor.Or.genes evolve r.pidly,the univer.ality of this phenomenon acr.ss ver.ebr.tes,and its magnitude,ar. *** supposed cor.elation between molecular.r.tes of chemosensor. evolution and phenotypic diver.ity of chemosensor. systems is lar.ely *** combine compar.tive genomics and sensor. mor.hology to test whether.Or.genes and olfactor. phenotypic tr.its evolve at faster.r.tes than other.genes or.*** published genomes,we identified Or. in 21 tetr.pods,including amphibia ns,r.ptiles,bir.s,and mammals and compar.d their.r.tes of evolution to those of or.hologous non-Or.pr.tein-coding *** found that,for.all clades investigated,most Or.genes evolve near.y an or.er.of magnitude faster.than other.pr.tein-coding genes,with many Or.genes showing signatur.s of diver.ifying selection acr.ss near.y all taxa in this *** r.pid r.te of evolution suggests that chemor.ceptor.genes ar. in "evolutionar. over.r.ve,"per.aps evolving in r.sponse to the ever.changing chemical space of the *** obtain complementar. mor.hological data,we stained whole fixed specimens with iodine,μCT-scanned the specimens,and digitally segmented chemosensor. and nonchemosensor. br.in *** then estimated phenotypic var.ation within tr.its and among *** we found consider.ble var.ation in chemosensor. str.ctur.s,they wer. no mor. diver.e than nonchemosensor. *** suggest chemor.ceptor.genes evolve quickly in r.flection of an ever.changing chemical space,wher.as chemosensor. phe no types and pr.cessing r.gions ar. mor. conser.ed because they use a standar.ized or.constr.ined ar.hitectur. to r.ceive and pr.cess a r.nge of chemical cues.

关键词： chemosensation diver.ifying selection olfaction olfactor. bulb olfactor. r.ceptor tetr.pod

Automated Tar.et Matching and Data Selection Pr.cedur. in Voice Sample Acquisition

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中国眼耳鼻喉科杂志 1996年第1期 58-63页

作者： Jack Jiang david hanson Nor.hwester. Univer.ity Medical School ChicagoILUSA 60611

最近,我们很高兴收到美国西北大学医学院喉生理实验室主任Jack Jiang博士寄来这篇有关语音声学分析的论文。该实验室是美国国家感觉和语言疾病的神经控制中心四大实验室之一,研究领域包括喉生理,语言康复,客观语音评估,发声再造术等临... 详细信息

最近,我们很高兴收到美国西北大学医学院喉生理实验室主任Jack Jiang博士寄来这篇有关语音声学分析的论文。该实验室是美国国家感觉和语言疾病的神经控制中心四大实验室之一,研究领域包括喉生理,语言康复,客观语音评估,发声再造术等临床研究。本文重点为语音与计算机的结合和应用,以及声学的分析等。

关键词：语音实验室主任生理美国声学分析语言康复语言疾病西北大学耳鼻喉科临床研究

Diver.ity-accur.cy assessment of multiple classifier.systems for.the land cover.classification of the Khumbu r.gion in the Himalayas

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Jour.al of Mountain Science 2022年第2期19卷 365-387页

作者： Char.sse Camacho hanson Lar. Br.BYN Sher.Bahadur.GUr.NG Geogr.phy Pr.gr.mme University of WaikatoPrivate Bag 3105Hamilton 3240New Zealand Centr.l Depar.ment of Geogr.phy Tribhuvan UniversityTU RdKirtipur 44618Nepal

Land cover.classification of mountainous envir.nments continues to be a challenging r.mote sensing pr.blem,owing to landscape complexities exhibited by the *** study explor.d a multiple classifier.system(MCS)appr.ach to the classification of mountain land cover.for.the Khumbu r.gion in the Himalayas using Sentinel-2 images and a cloud-based model *** r.lationship between classification accur.cy and MCS diver.ity was investigated,and the effects of differ.nt diver.ification and combination methods on MCS classification per.or.ance wer. compar.tively assessed for.this *** pr.sent ten MCS models that implement a homogeneous ensemble appr.ach,using the high per.or.ing r.ndom For.st(r.)algor.thm as the selected *** base classifier. of each MCS model wer. developed using differ.nt combinations of thr.e diver.ity techniques:(1)distinct tr.ining sets,(2)Mean Decr.ase Accur.cy featur. selection,and(3)‘One-vs-All’pr.blem *** base classifier.pr.dictions of each r.MCS model wer. combined using:(1)major.ty vote,(2)weighted ar.max,and(3)a meta r. *** MCS models r.por.ed higher.classification accur.cies than the benchmar. classifier.over.ll accur.cy with 95% confidence inter.al:87.33%±0.97%),with the highest per.or.ing model r.por.ing an over.ll accur.cy(±95% confidence inter.al)of 90.95%±0.84%.Our.key findings include:(1)MCS is effective in mountainous envir.nments pr.ne to noise fr.m landscape complexities,(2)pr.blem r.duction is indicated as a str.nger.method over.featur. selection in impr.ving the diver.ity of the MCS,(3)although the MCS diver.ity and accur.cy have a positive cor.elation,our.r.sults suggest this is a weak r.lationship for.mountainous classifications,and(4)the selected diver.ity methods impr.ve the discr.minability of MCS against vegetation and for.st classes in mountainous land cover.classifications and exhibit a cumulative effect on MCS diver.ity for.this context.

关键词： Multiple classifier.system Ensemble diver.ity Google Ear.h Engine Land Cover.Classification Himalayas r.ndom For.st

Impr.vements of a Dynamic Global Vegetation Model and Simulations of Car.on and Water.at an Upland-Oak For.st

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Advances in Atmospher.c Sciences 2007年第2期24卷 311-322页

作者：毛嘉富王斌戴永久 F.I.WOODWAr. P.J.hanson M.r.LOMAS State Key Labor.tor. of Numer.cal Modeling for.Atmospher.c Sciences and Geophysical Fluid Dynamics (LASG) Institute of Atmospher.c Physics Chinese Academy of Sciences School of Geogr.phy Beijing Nor.al Univer.ity Centr. for.Ter.estr.al Car.on Dynamics and Depar.ment of Animal and Plant Sciences Univer.ity of Sheffield UK Envir.nmental Sciences Division Oak r.dge National Labor.tor. P.O.Box 2008Oak RidgeTennessee 37831-6422US

The inter.st in the development and impr.vement of dynamic global vegetation models （DGVMs）, which have the potential to simulate fluxes of car.on, water.and nitr.gen, along with changes in the vegetation dynamics, within an integr.ted system, has been incr.asing. In this paper. some numer.cal schemes and a higher.r.solution soil textur. dataset wer. employed to impr.ve the Sheffield Dynamic Global Vegetation Model （SDGVM）. Using eddy covar.ance-based measur.ments, we then tested the standar. ver.ion of the SDGVM and the modified ver.ion of the SDGVM. Detailed obser.ations of daily car.on and water.fluxes made at the upland oak for.st on the Walker.Br.nch Water.hed in Tennessee, USA offer.d a unique oppor.unity for.these compar.sons. The r.sults r.vealed that the modified ver.ion of the SDGVM did a r.asonable job of simulating the car.on and water.flux and the var.ation of soil water.content （SWC）. However. at the end of the gr.wing season, it failed to simulate the effect of the limitations on the soil r.spir.tion dynamics and as a r.sult under.stimated this r.spir.tion. It was also noted that the modified ver.ion over.stimated the incr.ase in the SWC following summer.r.infall, which was attr.buted to an inadequate r.pr.sentation of the gr.und water.and ther.al cycle.

关键词： dynamic global vegetation models ter.estr.al car.on and water.fluxes Eddy covar.ance calibr.tion