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技师学院“工学一体化”人才培养路径研究

时代汽车 2024年第6期 50-52页

作者：李楚楚唐敬文浙江交通技师学院浙江省金华市321000

在产业转型升级的背景下,高素质技能人才培养亟待理论与实践紧密结合。技师学院要实现“工学一体化”人才培养,需要从专业设置、课程体系、教学模式等方面进行改革创新。文章首先概括阐述了“工学一体化”人才培养的内涵,分析了其对技... 详细信息

在产业转型升级的背景下,高素质技能人才培养亟待理论与实践紧密结合。技师学院要实现“工学一体化”人才培养,需要从专业设置、课程体系、教学模式等方面进行改革创新。文章首先概括阐述了“工学一体化”人才培养的内涵,分析了其对技师学院的重要意义,指出了当前技师学院在人才培养过程中存在的一些突出问题,然后从调整专业设置、构建工学一体化的课程体系、实施项目驱动教学法、强化实训条件建设等方面探讨了实现路径,最后对推进技师学院“工学一体化”人才培养提出了建议。

关键词：技师学院工学一体化人才培养

Drag Reduction in the Mouthpart of a Honeybee Facilitated by Galea Ridges for Nectar-Dipping Strategy

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Journal of Bionic Engineering 2015年第1期12卷 70-78页

作者： chuchu li Jianing Wu Yunqiang Yang Rengao Zhu Shaoze Yan Division of Intelligent and Biomechanical Systems State Key Laboratory of Tribology Department of Mechanical Engineering Tsinghua University Beijing 100084 China School of Engineering and Technology China University of Geosciences Beijing 100083 China

Some nectarivorous animals have evolved highly specialized tongues to gather nectar from flowers. Here we show that the Italian honeybee, Apis mellifera ligustica, uses the uniformly-distributed ridges on the internal wall of the mouthpart to reduce drag while drinking nectar. We discovered that the tip of the tongue is covered with bushy setae and resembles a brush, and the ridges are parallel distributed on the inner wall of the galeae. Using high-speed camera, we recorded the morphology of the mouthpart when dipping the sucrose water. Considering the ridges and the movement rule of the glossa, we proposed a model for analyzing the mechanism of drag reduction. Theoretical estimation of the friction coefficient with respect to the dipping frequency indicates that the erectable bushy hairs and the ridges can significantly reduce friction when a honeybee drinks nectar. Results show that dimensions of the ridges play a key role in reducing friction. It can be concluded that the ridges on the galeae of honeybee＇s mouthpart can reduce the friction coefficient by 86% compared with the case of the transverse distribution co- efficient S = 40. Finally, the capability of drag reduction in the mouthpart of honeybee may inspire a creative concept for de- signing efficient viscous micropumps.

关键词： honeybee mouthpart ridges drag reduction micropump

The Honeybee＇s Protrusible Glossa is a Compliant Mechanism

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Journal of Bionic Engineering 2017年第4期14卷 607-615页

作者： Yunqiang Yang Jianing Wu Rengao Zhu chuchu li Shaoze Yan School of Engineering and Technology China University of Geosciences (Beijing) Beijing 100083 China Division of lntelligent and Biomechanical Systems State Key Laboratory of Tribology Department of Mechanical Engineering Tsinghua University Beijing 100084 China

Many biological structures can perform highly-dexterous actions by using dynamic surfaces. To deal with the contradictive demands of high feeding efficiency and low energy expenditure during nectar feeding, the glossal surface of a honeybee un- dergoes shape changes, in which glossal hairs erect together with segment elongation in a drinking cycle. In this paper, we extracted a transmission link embedded in the glossa from postmortem examination and found that the compliance of the in- tersegmental membranes provides more possibilities for this highly kinematic synchronicity. According to the morphing phe- nomena of honeybee＇s glossa, we proposed a compliant mechanism model to predict the deformation behavior of honeybee considering elastic properties of the glossal intersegmental membranes. The increase of membrane stiffness may improve the capacity of elastic potential energy transfer, but will still result in the increase of mass. An index is introduced to evaluate the contradiction for optimizing structural parameters. This work may arouse new prospects for conceptual design of mi- cro-mechanical systems equipped with bio-inspired compliant mechanisms.

关键词： honeybee glossal membrane compliant mechanism stiffness evaluation

新型冠状病毒原始株和流行株IgG抗体组合识别Omicron BA.5流行株感染的研究

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中华预防医学杂志 2024年第9期58卷 1354-1359页

作者：储金金田华李楚楚李志锋董晨孔筱筱彭杰夫许可胡建利鲍倡俊朱立国江苏省疾病预防控制中心急性传染病防制所南京210009 江苏省现场流行病学培训项目南京210009 江苏省新发突发重大传染病病原微生物重点实验室江苏省疾病预防控制中心南京210009

目的探讨新型冠状病毒特异性IgG抗体组合在识别Omicron BA.5流行株感染的应用。方法选择新冠高强度流行后的Omicron BF.7/BA.5自然感染人群、疫苗免后健康人群和免疫突破感染Omicron BF.7/BA.5病例为研究对象,应用间接EliSA法检测血清... 详细信息

目的探讨新型冠状病毒特异性IgG抗体组合在识别Omicron BA.5流行株感染的应用。方法选择新冠高强度流行后的Omicron BF.7/BA.5自然感染人群、疫苗免后健康人群和免疫突破感染Omicron BF.7/BA.5病例为研究对象,应用间接EliSA法检测血清原始株和流行株特异性IgG抗体滴度,并比较不同人群血清特异性IgG抗体水平。应用ROC曲线探索新型冠状病毒原始型Spike IgG抗体(WT-S-IgG)和新型冠状病毒Spike(Omicron BA.5)IgG抗体(BA.5-S-IgG)两种抗体滴度以及两种抗体滴度比值在识别流行Omicron BA.5株感染中的应用价值,为病原体诊断提供技术支撑。结果免疫突破感染Omicron BF.7/BA.5病例的WT-S-IgG和BA.5-S-IgG两种抗体滴度水平明显高于Omicron BF.7/BA.5自然感染人群和疫苗免后健康人群(均P30 d流行株感染的ROC曲线下面积分别为0.887和0.863,灵敏度和特异度均达到80%以上。结论BA.5-S-IgG和WT-S-IgG两种血清抗体滴度及其比值在识别Omicron BA.5流行株感染具有较高应用价值。

关键词：新型冠状病毒间接EliSA IgG抗体抗体组合

G Ⅱ.17[P17]型诺如病毒基因系统发育聚类特征分析

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国际病毒学杂志 2024年第1期31卷 8-11页

作者：李楚楚艾静秦圆方朱立国胡建利鲍倡俊付建光江苏省疾病预防控制中心卫健委肠道病原微生物重点实验室南京210009

目的了解GⅡ.17[P17]型诺如病毒不同基因的发育聚类特征,为GⅡ.17[P17]序列的准确聚类提供依据.方法收集2023年3月至5月聚集性疫情中的GⅡ.17[P17]阳性标本,二代测序获得全基因组序列,与GenBank下载的参考株序列共同构建进化树,分别对... 详细信息

目的了解GⅡ.17[P17]型诺如病毒不同基因的发育聚类特征,为GⅡ.17[P17]序列的准确聚类提供依据.方法收集2023年3月至5月聚集性疫情中的GⅡ.17[P17]阳性标本,二代测序获得全基因组序列,与GenBank下载的参考株序列共同构建进化树,分别对各基因(Nterm、NTP、P22、VPg、Pro、RdRp、VP1和VP2)序列进行系统发育聚类分析及熵值分析.结果16个GⅡ.17[P17]阳性标本中共14个获得了全基因组序列,测序深度及覆盖度均较高.首先构建RdRp及VP1基因的系统发育进化树,发育聚类均为6个簇(ClusterⅠ~Ⅵ),其中ClusterⅠ~Ⅳ聚类相同,Cluster V~Ⅵ聚类有少量差异.2023年的标本株序列位于Cluster V.以RdRp聚类为基准,对病毒的8个基因片段进行聚类分析,发现NTP、RdRp和VP1基因聚类效果较好,6个簇均未形成新的分支.此外,这三个基因的熵值位点构成比也处于较低水平.结论诺如病毒GⅡ.17[P17]型别不同基因的系统发育聚类有一定差异,其中NTP、RdRp和VP1基因聚类效果较好.

关键词：诺如病毒基因系统发育聚类

PHONOLOGICAL PERCEPTION AND PROCESSING IN A SECOND LANGUAGE

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当代外语研究 2012年第12期384卷 94-109页

作者： MIN WANG chuchu li University of Maryland College Park

Phonological perception and processing is not only important in spoken language recognition and comprehension,but also important in the development of reading *** review paper examined phonological perception and processing in a second language(L2 )among infants,school-aged children,and *** are born with the ability to discriminate universal sets of phonetic distinctions,but this ability may decline or be lost later on due to lack of corresponding linguistic *** both children and adults,their L2 phonological processing skill is influenced by their L1 knowledge and not only L1 phonology but also the orthography impacts the L2 phonological processing.L1 phonological skills contribute to the development of L2 reading skills over and above the within-L2 phonological *** and future research direction are discussed.

关键词：英语教学教学方法课堂教学阅读教学

Spermine increases bactericidal activity of silver-nanoparticles against clinical methicillin-resistant Staphylococcus aureus

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Chinese Chemical Letters 2018年第12期29卷 1824-1828页

作者： Chang liu Han Shen Su Wang Xiaoli Cao Hongpan Xu Yanyan Xia Tingting Bai Yufeng liu lijun Peng chuchu li Zhirui Guo Zhiyang li Department of Clinical Laboratory The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Department of Geriatrics The Second Affiliated HospitalKey Laboratory for Aging&DiseaseNanjing Medical UniversityNanjing 210011China College of life Science Yangtze UniversityJingzhou 434025China Department of Technical Services Jiangsu Provincial Center for Disease Prevention and ControlNanjing 210009China

Methicillin-resistant Staphylococcus aureus(MRSA) has emerged worldwide as a major multidrugresistant pathogen that causes notable morbidity and mortality. Fast emerging of MRSA prevalence requires special attention for strengthening the inventory of antimicrobial compounds. Silver nanoparticles(AgNPs) have been widely used to treat multi-drug resistant pathogens due to the unique antibacterial properties, meanwhile spermine has been proven to exert outstanding inhibition effect to *** with not yet fully understood mechanisms. The aim of this study was to investigate the synergistic effect of AgNPs and spermine as well as to determine the antibacterial activity of their combination against MRSA strains. Several clinical MRSA isolates and ATCC BAA-1026 were used to determine minimum inhibitory concentration(MIC) and fractional inhibitory concentration indices(FICI) of AgNPs and spermine, and a synergistic effect was observed. This phenomenon was further confirmed by growth curve and time-killing assays, showed that spermine could be used as an adjuvant for AgNPs in the treatment of MRSA infections.

关键词： Spermine Silver nanoparticles Staphylococcus aureus Synagistic effect Antimicrobial

A New Heat Transfer Model for Multi-Gradient Drilling with Hollow Sphere Injection

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Fluid Dynamics & Materials Processing 2024年第3期20卷 537-546页

作者： Jiangshuai Wang chuchu Cai Pan Fu Jun li Hongwei Yang Song Deng School of Petroleum and Natural Gas Engineering Changzhou UniversityChangzhouChina CNPC Research Institute of Engineering Technology Co. Ltd.BeijingChina National Engineering Research Center for Oil&Gas Drilling and Completion Technology BeijingChina College of Petroleum Engineering China University of Petroleum(Beijing)BeijingChina College of Petroleum Karamay CampusChina University of Petroleum(Beijing)BeijingChina

Multi-gradient drilling is a new offshore drilling *** accurate calculation of the related wellbore temperature is of great significance for the prediction of the gas hydrate formation area and the precise control of the wellbore *** this study,a new heat transfer model is proposed by which the variable mass flow is properly taken into *** this model,the effects of the main factors influencing the wellbore temperature are *** results indicate that at the position where the separation injection device is installed,the temperature increase of the fluid in the drill pipe is mitigated due to the inflow/outflow of hollow spheres,and the temperature drop of the fluid in the annulus also *** addition,a lower separation efficiency of the device,a shallower installation depth and a smaller circulating displacement tend to increase the temperature near the bottom of the annulus,thereby helping to reduce the hydrate generation area and playing a positive role in the prevention and control of hydrates in deepwater drilling.

关键词： Multi-gradient drilling wellbore temperature hydrate separate injection device variable mass

A Novel Feature-based Method for Sentiment Analysis of Chinese Product Reviews

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China Communications 2014年第3期11卷 154-164页

作者： liU lizhen SONG Wei WANG Hanshi li chuchu LU Jingli Information and Engineering College Capital Normal University Beijing 100048 P. R. China Agresearch Ltd New Zealand

Sentiment analysis of online reviews and other user generated content is an important research problem for its wide range of *** this paper,we propose a feature-based vector model and a novel weighting algorithm for sentiment analysis of Chinese product ***,an opinionated document is modeled by a set of feature-based vectors and corresponding *** from previous work,our model considers modifying relationships between words and contains rich sentiment strength descriptions which are represented by adverbs of degree and *** parsing is applied to construct the feature vectors.A novel feature weighting algorithm is proposed for supervised sentiment classification based on rich sentiment strength related *** experimental results demonstrate the effectiveness of the proposed method compared with a state of the art method using term level weighting algorithms.

关键词： sentiment analysis sentimentstrength opinion mining dependency parsing