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含贯通小孔和排列微槽的血管组织工程用仿真支架制备

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含贯通小孔和排列微槽的血管组织工程用仿真支架制备

2007年全国高分子学术论文报告会

作者：冯杰 Mary chan-park B 浙江工业大学高分子科学与工程研究所 SCBE Nanyang Technological University（NTU） Singapore639798

＜正＞血管平滑肌细胞（SMC）在管壁上的周向排列以及内皮细胞（EC）在管内腔的纵向致密排列是体外或部分体内工程化血管时面临的两个主要问题。在以往的研究中,我们发现排列微槽可以很好地诱导 SMC 延其长轴方向伸展、排列甚至表型转变... 详细信息

＜正＞血管平滑肌细胞（SMC）在管壁上的周向排列以及内皮细胞（EC）在管内腔的纵向致密排列是体外或部分体内工程化血管时面临的两个主要问题。在以往的研究中,我们发现排列微槽可以很好地诱导 SMC 延其长轴方向伸展、排列甚至表型转变,其他人则证实支架中

关键词：血管组织工程小孔仿生支架微构建技术冷冻干燥

New anti-mesenteric delta-shaped stapled anastomosis: Technical report with short-term postoperative outcomes in patients with Crohn’s disease

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2592-2601页

作者： Jong Lyul Lee Yong Sik Yoon Hyun Gu Lee Young Il Kim Min Hyun Kim chan Wook Kim In Ja park Seok-Byung Lim chang Sik Yu Division of Colon and Rectal Surgery Department of SurgeryUniversity of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea Department of Surgery Gangdong Kyung Hee University HospitalSeoul 05278South Korea

BACKGROUND Medical treatment for Crohn’s disease(CD)has continuously improved,which has led to a decrease in surgical recurrence *** these advancements,25%of patients will undergo repeat intestinal *** of CD com-monly occurs on the mesentery side of the anastomosis *** To compare the new anti-mesenteric side-to-side delta-shaped stapled anasto-mosis(DSA)with the conventional stapled functional end-to-end anastomosis(CSA).METHODS This retrospective study included CD patients who underwent ileo-ileal or ileo-colic anastomosis between January 2020 and December *** DSA technique employed a stapler to maintain the concept of anti-mesentery side-to-side ana-stomosis by performing a 90°vertical closure of the open window compared with the CSA *** the corner where the open window is closed,the DSA avoids forming a pouch and creates an anastomosis resembling a delta shape within the intestinal *** compared demographics,preoperative condition,operative findings,and operative outcomes for the two *** The study included 175 patients,including 92 in the DSA group and 83 in the CSA *** two groups were similar in baseline characteristics,preoperative medical treatment,and operative findings except for the Montreal classification *** 30-days postoperative complication rate was signi-ficantly lower in the DSA group compared with the CSA group(16.3%vs 32.5%,P=0.009).Ileus incidence was significantly lower in the DSA group than in the CSA group(4.3%vs 14.5%,P=0.033),and the hospital stay was shorter in the DSA group than in the CSA group(5.67±1.53 days vs 7.39±3.68 days,P=0.001).CONCLUSION The DSA technique was feasible and showed comparable postoperative outcomes with lower short-term complic-ations compared with the CSA *** studies on CD recurrence and long-term complications are warranted.

关键词： Crohn’s disease Surgery Anastomosis Complication Recurrence

A Parallel Hopfield Neural Network Guaranteeing the Convergence

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A Parallel Hopfield Neural Network Guaranteeing the Converge...

IJCNN International Joint Conference on Neural Networks

作者： chan Hee park Jong H.Nang Jin S.Kim H.Yoon Jung W.Cho Department of Computer Science and Center for AI Research Korea Advanced Institute of Science and Technology（KAIST） 373-1 Kusong-Dong Yusung-Gu Taejon 305-701Korea

＜正＞This paper aims to operate the Hopfield neural network model in parallel by means of a new state updating rule,called the majority *** rule is characterized by that a neuron in a parallel Hopfield model changes its state only when the net-input is considerably larger（or smaller） than its threshold regardless of the states of other neurons that operate simultaneously. While the original Hopfield network may not converge if it operate in parallel,the convergence of the proposed parallel Hopfield network is guaranteed thanks to the novel concept of majority *** convergence property of the proposed network is theoretically proved by showing that the energy of network is always monotonically non-decreasing when a state transition with majority protocol is *** addition,this paper demonstrates its usefulness by applying the parallel Hopfield model to well-known combinatorial optimization problems.

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Exploring the synergy of the eyebrain connection:neuromodulation approaches for neurodegenerative disorders through transcorneal electrical stimulation

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Neural Regeneration Research 2024年第10期19卷 2097-2098页

作者： Antara Verma Stephen K.Agadagba Leanne Lai-Hang chan Department of Electrical Engineering City University of Hong KongKowloonHong Kong Special Administrative RegionChina Centre for Eye and Vision Research Ltd. Hong Kong Special Administrative RegionChina Pennsylvania State University University ParkPAUSA

The connection and interaction between the eye and the brain are crucial to understanding brain disorders(Marchesi et al.,2021).Both the eye and the brain have a limited regenerative capacity as there are few progenitor cells,and nerve cells do not ***,neurodegeneration implicates irreversible damage to the central nervous system,as observed in several neurodegenerative diseases(Marchesi et al.,2021).

关键词： stimulation degenerative

EM STUDIES OF MISFIT STRAIN AND STRUCTURE EVOLUTION OF SELF-ASSEMBLED InAs/GaAs QUANTUM DOT HETEROSTRUCTURES

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EM STUDIES OF MISFIT STRAIN AND STRUCTURE EVOLUTION OF SELF-...

第十一届北京分析测试学术报告会暨展览会(BCEIA 2005)

作者： Hyung Seok Kim Ju Hyung Suh chan Gyung park Sang Jun Lee Sam Gyu Noh Jin Dong Song Yong Ju park Won Jun Choi Jung Il Lee Department of Materials Science and Engineering Pohang University of Science and Technology (POSTECH) Quantum Dot Technology Laboratory Korea Research Institute of Standards and Science (KRISS)

Compound semiconductor heterostructures which have different energy band gaps have recently been grown easily owing to the technical development of epitaxial thin film ***,extensive studies have been carried out on th...

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药品监管和可专利性环境中“新化学单体”的定义

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药品监管和可专利性环境中“新化学单体”的定义

作者： chan S.park 李雪莹世界卫生组织国家知识产权局专利局

"新化学单体"(new chemical entity)的概念出现在TRIPS协议第39.3条中,但没有给出定义。如何定义"新化学单体"目前仍缺乏明确共识。本文探讨了"新化学单体"在药品监管等不同环境中已有的定义,并说明采用不同定义对数据保护/独占范围的...

"新化学单体"(new chemical entity)的概念出现在TRIPS协议第39.3条中,但没有给出定义。如何定义"新化学单体"目前仍缺乏明确共识。本文探讨了"新化学单体"在药品监管等不同环境中已有的定义,并说明采用不同定义对数据保护/独占范围的潜在影响。进(?)地,分析了定义该概念中存在灵活性的参数,发展中国家可以充分利用这些灵活性,采用一种最能有效地促进廉价仿制药的快速上市的定义。

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近地轨道编队飞行航天器利用CDGPS和星间通信系统的测量技术

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控制工程（北京） 2005年第4期 47-59页

作者： chan—Woo park Jonathan P．How Larry Capots

本文介绍近地轨道（LEO）编队飞行航天器利用载波相位差分GPS（CDGPS）敏感器和GPS类无线电收发两用机这些测量技术的有关研究工作。编队飞行需要采用高级的星间通信系统。目前，已开发了用于编队飞行的几种无线电通信设备，这些设备也... 详细信息

本文介绍近地轨道（LEO）编队飞行航天器利用载波相位差分GPS（CDGPS）敏感器和GPS类无线电收发两用机这些测量技术的有关研究工作。编队飞行需要采用高级的星间通信系统。目前，已开发了用于编队飞行的几种无线电通信设备，这些设备也可作为星上测距系统。若采用辅助的星间测距和多谱勒测量手段提供导航解，这些星上发射机就有助于CDGPS在用户星对导航星星座的可观性／几何配置不良的轨道上使用。另外，载波相位周期模糊度可利用卫星相对运动快速初始化。本文详细讨论了这种改进方案，并推荐前人的研究成果，这就显著地改善了偏差初始化过程。文章中提出了被长基线（10～100kin）间隔的编队飞行航天器的主要测量误差。最后介绍了新型地面试验台的试验数据。该地面试验台已经研制出来，它与导航星和星上GPS发射机组合在一起，用来研究相对导航和编队飞行。结果表明，编队卫星可以实现快速初始化和编队机动。

关键词：编队飞行测量技术近地轨道通信系统航天器无线电通信设备载波相位差分初始化过程测距系统导航星

碳纳米管的表面改性——迈向聚合物基复合材料高性能化的第一步

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碳纳米管的表面改性——迈向聚合物基复合材料高性能化的第一步

2007年全国高分子学术论文报告会

作者：闫业海崔健 Mary B.chan-park 青岛科技大学高分子科学与工程学院橡塑材料与工程教育部重点实验室青岛科技大学高分子科学与工程学院橡塑材料与工程教育部重点实验室 School of Chemical and Biomedical Engineering Nanyang Technological University Singapore637459

＜正＞欲制备出高性能化的聚合物基碳纳米管复合材料,解决碳纳米管于基体树脂中的分散和界面粘合问题是关键。对碳纳米管表面进行有针对性的化学改性被广泛视为解决该问题的一个较好切入点。为此,本文将报道两个对碳纳米管进行表面化学... 详细信息

＜正＞欲制备出高性能化的聚合物基碳纳米管复合材料,解决碳纳米管于基体树脂中的分散和界面粘合问题是关键。对碳纳米管表面进行有针对性的化学改性被广泛视为解决该问题的一个较好切入点。为此,本文将报道两个对碳纳米管进行表面化学改性的实例其一,通过等离

关键词：碳纳米管表面改性等离子体辅助紫外接枝改性分散性

Inhibition of pacemaker activity in interstitial cells of Cajal by LPS via NF-κB and MAP kinase

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World Journal of Gastroenterology 2013年第8期19卷 1210-1218页

作者： Dong Chuan Zuo Seok Choi Pawan Kumar Shahi Man Yoo Kim chan Guk park Young Dae Kim Jun Lee In Yeoup chang Insuk So Jae Yeoul Jun Department of Physiology College of MedicineChosun UniversityGwangju 501-759South Korea Department of Internal Medicine College of MedicineChosun UniversityGwangju 501-759South Korea Department of Anatomy College of MedicineChosun UniversityGwangju 501-759South Korea Department of Physiology and Biophysics College of MedicineSeoul National UniversitySeoul 56-1South Korea

AIM:To investigate lipopolysaccharide(LPS) related signal transduction in interstitial cells of Cajal(ICCs) from mouse small ***:For this study,primary culture of ICCs was prepared from the small intestine of the *** was treated to the cells prior to measurement of the membrane currents by using whole-cell patch clamp *** was used to examine the expression of the proteins in ***:LPS suppressed the pacemaker currents of ICCs and this could be blocked by AH6809,a prostaglandin E2-EP2 receptor antagonist or NG-Nitro-Larginine Methyl Ester,an inhibitor of nitric oxide(NO) ***-like receptor 4,inducible NO synthase or cyclooxygenase-2 immunoreactivity by specific antibodies was detected on ***(antioxidant agent) had no action on LPS-induced action in *** actions were blocked by nuclear factor kB(NF-kB) inhibitor,actinomycin D(a gene transcription inhibitor),PD 98059(a p42/44 mitogen-activated protein kinases inhibitor) or SB 203580 [a p38 mitogen-activated protein kinases(MAPK) inhibitor].SB 203580 also blocked the prostaglandin E2-induced action on pacemaker currents in ICCs but not ***:LPS inhibit the pacemaker currents in ICCs via prostaglandin E2-and NO-dependent mechanism through toll-like receptor 4 and suggest that MAPK and NF-kB are implicated in these actions.

关键词： Interstitial cells of Cajal Lipopolysaccharide Mitogen-activated protein kinases Nuclear factor kB Small intestine